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JaLCDOI 10.18926/21229
Title Alternative A report on the physically handicapped persons caused by rheumatoid arthritis in Tottori Prefecture, Japan
FullText URL 044_055_060.pdf
Author Kitayama, Minoru|
Abstract The physically handicapped persons caused by rheumatoid arthritis were studied in Tottori prefecture in July 1973. The following results were obtained ; 1. The hand i capped per sons of 265, who were recognized as the handicapped by the government authori ties, were observed. The prevalence rate was 4.7 to 10,000 of the population and 15 to 1, 000 of the total number of the hand i capped. 2. The prevalence rate of the handicapped to the total number of patients with rheumatoid arthritis was 15.4%. 3. On a reginal distribution, the prevalence rate of the handicapped to the regional population were calculated between from 0.20‰ to 0.77‰. The result showed that it was higher at rural than at urban districts. 4. The prevalence rate to population gradually increased with aging, especially over the fiftieth years. The prevalence rate of the number of serious handicapped (class 1+2) to the total number of handicapped was regnlarly at 40% between 30 and 60 years of age, but it increased over 70 years of age. 5. The sex ratio of fernIe to male was 3.3 : 1 on the total handicapped and 2.9 : 1 on the serious handicapped persons. On the other hand, the ratio was 5.1 : 1 on the group under 59 year s of age and 2.4 : 1 on the groupe over 60 years of age at the total handicapped. And then, the ratio was 5.0 : 1 on the younger group and 2.6 : 1 on the older group at the serious handicapped persons.
Publication Title 岡山大学温泉研究所報告
Published Date 1975-03-25
Volume volume44
Start Page 55
End Page 60
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310975
JaLCDOI 10.18926/21228
Title Alternative Continuous in-vIvo measurement of the brain tissue and the ischemic muscle gas tension using MEDSPECT, MS-8
FullText URL pitsr_043_029_036.pdf
Author Kawakami, Shunji| Yamane, Yoshihisa| Noishiki, Yasuharu| Komoto, Yoshiaki| Teramoto, Shigeru| Senoh, Yoshimasa| Kaneko, Katsuya| Sugimoto, Seiki| Takahashi, Shunjiro|
Abstract I MEDSPECT is a medical mass spectrometer for continuous in-vivo measurement of tissue, blood and respiratory gases. Interfacing catheter for tissue in measurement has Teflon membrane. The permeability and perfusion rate for various gases through its membrane varied with temperature. The temperature coefficient of Teflon catheter in the range of 15℃-40℃ is approximately constant with -2% of correction per degree for oxygen and carbon dioxide. Linear correlation was confirmed experimentally. II The brain tissue gas tensions were measured in ten dogs with intra-venous anesthesia at normothermia and deep hypothermia using perfusion cooling, including circulatory arrest for 30 minutes at 20°C of cerebral temperature. On average, the brain tissue P(O2) was 15mmHg in normothermia when the arterial P(O2) showed 95mmHg and the brain tissue P(CO2) was 49mmHg when the arterial PC02 showed 30mmHg. The brain tissue carbon dioxide tension gradually decreased by cooling and increased during circulatory arrest for 30 minutes; from 45mmHg to 72mmHg. The brain tissue oxygen tension increased during cooling from 15mmHg to 41mmHg and decreased in the circulatory arrest; from 41mmHg to 36mmHg. III The ischemic muscle gas tension was measured in a 22-year-old man, who was suffered from thromboangiitis obliterans bilaterally, and had the popliteal autovein bypass surgery 3 months ago. Control oxygen tensions in the both anterior tibial muscles showed about the same; 35mmHg and 36mmHg respectivelly, and the P(O2) of the non-operated side showed remarkable low level of 18mmHg as compared with the side of arterial reconstruction surgery after 5-minutes ankle exercise.
Publication Title 岡山大学温泉研究所報告
Published Date 1974-03-25
Volume volume43
Start Page 29
End Page 36
ISSN 0369-7142
Related Url http://eprints.lib.okayama-u.ac.jp/21235
language Japanese
File Version publisher
NAID 120002311036
JaLCDOI 10.18926/21225
Title Alternative Some new data on granophyres (the Namariyama quarts-diorites) in the Ningyo-toge area
FullText URL pitsr_044_021_032.pdf
Author Honma, Hiroji|
Abstract A new occurrence of granophyric body was described and its geological significance was discussed with regard to classification of Late Cretaceous to Early Tertiary plutonic activities in the area.
Publication Title 岡山大学温泉研究所報告
Published Date 1975-03-25
Volume volume44
Start Page 21
End Page 32
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311029
JaLCDOI 10.18926/21215
Title Alternative Studies on lithium in the field of balneology : Effects of lithium salts on analgesic activity of aminopyrine
FullText URL pitsr_045_025_031.pdf
Author Furuno, Katsushi| Mifune, Masaaki|
Abstract The authors studied the effect of pretreatment with internal use of lithium salts on analgesic activity of aminopyrine by hot-plate test in mice. The male mice at 4 weeks of age weighting 17-19 g were divided into 7 groups. Earch group being composed of 9-10 mice was given oraBy 0.1 ml of LiCI-solution per 10 g of body weight for 35 days, LiCl was dissolved in 0.9% saline solution, in such concentrations that each group received 0 mg, 50 mg, 100mg, 200 mg and 400mg of LiCl for each kg of body weight of mouse, respectively, Control group received only 0.9% saline solution. On the 1st, 3rd, 7th, 14th, 21st, 28th and 35th days of this experiment, 0.1 ml of 1% solution of aminopyrine per 109 of body weight was injected intraperitoneaJly and then tested 30 minutes later. In the hot-plate test, a mouse is placed on a hot plate being adjusted with the thermostat at 55°±1℃, and the response is licking or lifting the hind feet or an outright attempt to escape from the plate, The increase in response time is used to quantify the analgesic effect of aminopyrine, The results were as follows : 1. The response time in groups receiving 0-50 mg of LiCl per kg of body weight had decreased on the 14 th day, but it tended to return to the initial level after the 21st day of experiment. 2. The response time in groups receiving 100-400 mg of LiCl per kg of body weight had also decreased on the 14 th day, and the degree of the decrease in response time was greater than that of the former and then remained faily constant at this level to the end of the observation period. These results would indicate that LiCl inhibits the analgesic activity of aminopyrine.
Publication Title 岡山大学温泉研究所報告
Published Date 1976-03-25
Volume volume45
Start Page 25
End Page 31
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311002
JaLCDOI 10.18926/21213
Title Alternative The effect of radioactive thermal bathing upon catecholamines of the whole brain of male mice
FullText URL pitsr_045_007_010.pdf
Author Ito, Keiko|
Abstract The author studied the changes of catecholamine levels of the whole brain of male mice weighing 15-20g before and after a single bathing for 20 minutes, 37±1℃ in temperature, in the radioactive hot spring in Misasa (Rn content : 74.83×10(-10)C/l), and compared the results obtained with those of the plain hot water bathing. The catecholamines (dopamine and noradrenaline) were measured by gaschromatographic method using electrone capture detector. It may be summarized as follows : 1. No significant change of dopamine and noradrenaline levels of the whole brain of mice was recognized before and after the plain hot water bathing used as a control. 2. Noradrenaline levels of the whole brain of mice had increased following the radioactive hot spring bath, and remained at same levels for 30 minutes after bathing. Dopamine levels had no change immediately after bathing, but had lowered at 30 minutes from the time of the bath. 3. Causes of these results are under investigation.
Publication Title 岡山大学温泉研究所報告
Published Date 1976-03-25
Volume volume45
Start Page 7
End Page 10
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310996
JaLCDOI 10.18926/21205
Title Alternative Hydrogen and oxygen isotopic ratios of thermal and mineral springs in Arima area
FullText URL pitsr_043_015_028.pdf
Author Matsubaya, Osamu| Sakai, Hitoshi| Tsurumaki, Michiji|
Abstract Saline waters of thermal and mineral springs in Arima area, at Takarazuka, and in Ishibotoke area of Kawachinagano City indicate wide ranges of δD and δ(18)O values (Table 1). Excellent linearity exists between the δD and δ(18)O values (Fig. 1) and between the δ(18)O value and the chloride concentration (Fig. 2). These facts as well as the chemical evidence of the previous investigators strongly support the view that Arima springs are admixtures of a single deep brine and local ground water (TSURUMAKI, 1964). The deep brine may have the δ(18)O value of +8.0~+8.5‰, the δD value of -25~-30‰, and the chloride concentration of 1.20~1.25 eq/l, which were estimated from the water of the maximum salinity so far reported. Because the thermal and mineral springs in Arima area closely associate with the upper Cretaceous granitic rocks, and the estimated δ(18)O value of the deep brine is similar to a value of water in isotopic equilibrium with those granitic rocks at 500~600℃, the deep brine of Arima might have been the magmatic water of those granitic rocks. The mineral springs at Takarazuka and in Ishibotoke area also show the similar linearity among Cl(-), δ(18)O and δD to those in Arima area. Therefore it is assumed that the mineral springs at Takarazuka may be of the same origin as that in Arima area, and the mineral springs in Ishibotoke area might have been the fluid associated with Ryoke metamorphic rocks. Alternatively, the deep brine in Arima area may be isotopically and chemically similar to the saline formation waters in Illinois basin (GRAF et al., 1966). The high δD values and salinities of those formation waters were attributed to the isotopic and chemical fractionation during the passage of water through sediments. The deep brine in Arima area may be genetically similar to those saline formation waters. If such a saline water could have formed in Osaka basin, it is not surprising to find out the similar brines at Arima and Ishibotoke which are the northwestern and southeastern rims of the basin, respectively. At the present, it cannot be answered which of these two models is more probable. Further studies on other saline springs fluid inclusions of Cretaceous granitic rocks may be useful in order to solve this problem.
Publication Title 岡山大学温泉研究所報告
Published Date 1974-03-25
Volume volume43
Start Page 15
End Page 28
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310971
JaLCDOI 10.18926/21204
Title Alternative Determination of manganese in serum by atomic absorption spectrophotometry
FullText URL pitser_046_037_043.pdf
Author Furuno, Katsushi|
Abstract The manganese (Mn) concentrations in serum of 40 healthy controls (9 males and 31 females), and of 26 patients with rheumatoid arthritis (4males and 22 females) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Wavelength of Mn determination was setted at 2795 A. Flow rate of acetylene was setted at 3.0 l/min and lamp current was setted at 10 rnA. The serum samples were ashed by IPC MODEL 1003plasma machine, and dissolved in 3N-HCl and evapolate on the hot plate, and redissolved in constant volume of 0.1 N-HCl. These sample solution were aspirated directly into the burner. Mn levels in serum were estimated by standard curve. The mean recoverry rate of ashedsample solution was 100.1%, and that of serum by ashing process was 101.6%. The serum Mn levels in 40 healthy controls and 26 patients with rheumatoid arthritis were 2.19 ± 0.34 (S.D.), 3.04 ± 1.01 (S.D.) μg/100ml respectively. The serum Mn levels in rheumatoid arthritis were significantly higher than healthy control levels (p<0.001). In 10 of 26 cases (38%) with rheumatoid arthritis, the serum Mn levels were shown to be above the upper limit of 5% rejection limit of healthy controls.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 37
End Page 43
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310997
JaLCDOI 10.18926/21203
Title Alternative Determination of copper and zinc in serum by atomic absorption spectrophotometry
FullText URL pitser_046_025_035.pdf
Author Furuno, Katsushi|
Abstract Copper (Cu) and Zinc (Zn) in serum of 113 healthy controls (43 males and 70 females) and of 68 patients with rheumatoid arthritis (19 males and 49 females) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Wavelength and lamps current of Cu and Zn were setted at 3247 A, 2139 A, and 10mA, 9mA respectively. Flow rate of acetylene and air were setted at 3.0 l/min, and 13.0 l/min. The stock standard solutions of Cu and Zn were 0.5 mg, 1.0mg, 2.0mg and 3.0mg per 100mE in 0.01 N·HCl. For working standard solutions, these stock standard solutions were diluted to 50μg/100ml. 100μg/100ml, 200μg/100ml and 300μg/100ml with 20% glycerine. Serum and working standard so· lutions of Cu and Zn were diluted five fold with deionized distillation water, then aspirated directly into the burner. The relative absorbance was expressed as scale reading by a HITACHI MODEL QPD-54 recorder. Various acids and other elements had few influences on the determi· nations of Cu and Zn. The mean recovery rate of Cu and Zn in serum were 100.5% and 100.8% respectively. By this method, the levels of Cu and Zn in healthy controls were 103.0±14.5 (S.D.), 116.2±18.6 (S.D.) μg/100ml in males and 108.7±19.6 (S. D.), 110.3±14.7 (S.D.) μg/100ml in females respectively. No sex difference were observed. The ratio of Cu and Zn (Cu/Zn ratio) of healthy controls were 0.89±0.17 (S. D.) in males and O.99±0.25 in (S.D.) females. The sex differrences of Cu/Zn ratio were statistically significant (p<0.05). The levels of Cu and Zn in rheumatoid arthritis were 141.7±25.2 (S.D.). 89.1±14.5 (S.D.) /-Lg/100 mP and 154.l±29.7 (S.D.), 86.7±18.1 (S.D.) μg/100ml in females respectively. No sex differren· ces were observed. The Cu/Zn ratio were 1.64±0.43 (S.D.) in males and 1.82±0.48 (S.D.) in females, wich showed no sex differrences. In patients with rheumatoid arthritis, serum Cu levels were significantly higher (P<0.001) and serum Zn levels were significantly lower (P<0.001) than in healthy controls in both sexes. The Cu/Zn ratio were significantly higher (P<0.001) rheumatoid arthritis than in controls. The serum Cu in 13 of 19 males (68%), and 30 of 49 females (61 %), with rheumatoid arthritis were shown to be above the upper limit of 5% rejection limit in healthy controls. The serum Zn in 3 of 19 males (16%), and in 24 of 49 (47%) with rheumatoid arthritis were shown to be below the lower limit 5% rejection limit in healthy controIs. The Cu/Zn ratio in rheumatoid arthritis, in 14 of 19 males (74%), and in 35 of 49 females (71%) were shown to be above the upper limit of 5% rejection limit in healthy of males and females. So, differences in Cu/Zn ratio between healthy controls and rheumatoid arthritis were proved to be more pronounced.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 25
End Page 35
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311019
JaLCDOI 10.18926/21202
Title Alternative Circulatory changes in rheumatoid fingers as estimated by thermography and photoelectric plethysmography
FullText URL pitser_046_015_023.pdf
Author Ohta, Takamasa| Tokioka, Masaaki| Takasugi, Kiyoshi|
Abstract In an attempt to evaluate circulatory changes in patients with rheumatoid arthritis (RA), 20 patients with classical or definite RA as determined by ARA criteria and twenty healthy volunteers serving as control were randomly selected. None of the patients showed the clinical signs suggesting Raynaud's phenomenon. Thermograms as well as photoelectric plethysmograms were obtained solely from the right middle finger tip of each examinee. The whole hand was then immersed in the cold (10℃) water and kept there for one minute. After wiping away the wet hand with a dry towel very gently, we followed the sequential changes of the tempe· rature of the third finger tip and the period of time necessary for the tip to return to the original temperature prior to the cold water immersion was measured and expressed as 'return time' in minute. Before exposure to the cold, the mean values of temperature of the finger tips between the two groups were not significantly different. As opposed to the normal pattern in which one can find the warmest point at the finger tip and which was more frequently found in the control group of the current study, a type in which the distal part of the finger was much cooler than the proximal area (so-called 'distal cold type') was observed in 8 RA patients, whereas only four demonstrated this pattern in the control group. After brief exposure to the cold, eight out of 20 rheumatoid patients showed much prolonged return time (longer than 20 minutes), while only three of 20 controls remained with prolonged cool periphery, The difference between the two, however, was not statistically significant. Studies of the digital plethysmograph revealed that 70% of all the rheumatoids showed abnormal patterns: sclerotic and monophasic waves were discovered in 55% of the patients. In contrast, seventy percent of the normal control demonstra· ted normal wave pattern. Although the significant difference was not noted, the mean height of the systolic peak of the plethysmograph derived from the rheumatoid group tended to be much reduced, suggesting the reduced blood volume at the finger tips. Six RA patients and 13 normals who showed normal plethysmographic pattern before immersion in the cold water, demonstrated rapid return to the original temperature. Only in one normal control with a normal wave pattern, prolonged return time was observed, although the height of the systolic peak of the plethysmogram in this particular case was well within normal limit. Digital circulatory disturbance, however, was strongly suspected in eight RA patients with severely prolonged return time, They all showed abnormal wave patterns of the plethysmogram, including 2 cases with peripheral plateau wave, Markedly reduced heights of the systolic peaks were also demonstrated in all. Further elaborate studies including digital arteriography were indicated to implicate any organic change in the digital vessels, such as digital arteritis in RA first reported by Bywaters in 1957.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 15
End Page 23
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310966
JaLCDOI 10.18926/21201
Title Alternative A case of cancer in the gastric remnant
FullText URL pitser_046_011_014.pdf
Author Noishiki, Yasuharu| Nakahara, Yasuhiro|
Abstract This is a report of cancer of the stomach encountered in a 71-year-old man who admitted to the hospital with complain of epigastralgia. He had undergo a two third gastrectomy with gastroduodenostomy 24 years before because of severe gastritis. For several years he had ambulatory treatment for diabetes mellitus, which was under good control. Laboratory examination revealed that red-cell count was 4,800,000, white-cell count 11,500 ; hemoglobin was 12.7gr. per 100ml, hematocrit 49.5 per cent. Total serum protein was 8.2%. The stool was positive for occult blood and the urine negative for protein. X-ray studies in barium filled stomach in upright position revealed a filling defect in the lessor curvature side. In the prone and supine double contrast studies, a lesion was visualized of irregular outline with marked surface unevenness. Endoscopically, a rough tumor resembling Borrman Type III cancer was found near the stoma on the anterior wall of gastric remnant. Marginal blending and convergency of the folds showing sudden cessation around the ulcer were recognized as well. These findings led the authors to the diagnosis of the cancer developing in the gastric remnant and total gastrectomy with esophagojejunostomia was performed. Reports of cancer in the gastric remnant detected more than 20 years after the first operation are so small in number.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 11
End Page 14
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310947
JaLCDOI 10.18926/21200
Title Alternative Fundamental study of post operative intestinal adhesion -Findings on early stage of peritoneal inflammation by ultraviolet irradiation-
FullText URL pitser_046_001_009.pdf
Author Noishiki, Yasuharu|
Abstract Early process of peritoneal inflammation on rat by ultraviolet irradiation was studied histologically and scanning electron microscopic· ally. After 1 minute irradiation of ultraviolet, minimal exudation on mesothelium was found. After 15 minutes irradiation, microvillies on mesothelium were covered with exudate. After 20 minutes, fibrin fibers appeared on intact mesothelium. Though the fibers wafted in exudate, the fibers could be cleared up by irrigation of saline. After 30 minutes, white and red cells appeared on the nest of fibrin fibers. After 45 minutes, edema came out at subserosal layer. After 1 hour, mesothelium was covered with fibrin fibers, white and red cells. But the coated fur could be washed off by jet irrigation of saline and intact mesothelium benearth the fur appeared. These results indicate that washing a peritoneal cavity by saline after abdominal operation is of practical value to prevent a intestinal adhesion due to post operative intestinal inflammation. Inflammatory changes of intestinal mesothlium was clearly demonstrated by scanning electron microscope and these observations revealed that scanning electron microscope was very useful for the study of inflammation which occured on the surfaces of organs.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 1
End Page 9
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310943
JaLCDOI 10.18926/21192
Title Alternative Enumeration of T-cells in peripheral blood as well as in joint fluid from patients with rheumatoid arthritis (RA) and the effect of cyclophosphamide
FullText URL pitsr_047_041_048.pdf
Author Tokioka, Masaaki| Takasugi, Kiyoshi|
Abstract Gradient centrifugation was quite useful in obtaining "mononuclear" cell fractions from synovial fluids derived from patients with rheumatoid arthritis. The ratio of lymphocytes to monocytoid cells was similar to that seen in peripheral blood. Prior treatment of the fluid with hyaluronidase was found to be necessary to obtain a satisfactory yield of the cells. Sheep erythrocyte rosette-forming lymphocytes (T-cells) were studied in 18 paired samples of synovial fluid and blood in RA and 15 control blood samples from normal persons were also examined. In the paired synovial fluid and blood samples from the RA patients, the mean percentages of the T-cells were 56.6 and 47.1 respectively and the difference was statistically significant (0.01
Publication Title 岡山大学温泉研究所報告
Published Date 1978-03-25
Volume volume47
Start Page 41
End Page 48
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310963
JaLCDOI 10.18926/21191
Title Alternative Petrological study of the Okutsu granodioritic mass in the northern part of Okayama Prefecture. Japan - Part 1 Geology and petrography
FullText URL pitsr_047_033_040.pdf
Author Sakiyama, Tooru|
Abstract The Late Mesozoic granitic rocks have been studied in the Okutsu area, northern Okayama Prefecture. Main portion of the area is occupied by the Okutsu granodioritic mass. It consists of mediumgrained hornblende-biotite granodiorite, mediumgrained biotite granite, fine-grained biotite granite, and aplitic granite in the succeeding order of intrusion. Contacts between these rock-types are generally gradational and An-contents of both core and margin of the plagioclase progressively decrease with increasing acidity of the rocks. These facts indicate a cognate origin of various rock-types of this mass. The Kamisaibara granite, rather uniform coarse-grained hornblende-biotite granite, occurs in large batholith. It is inferred petrographically that the Kamisaibara granite is a member of the Ningy6,t6ge granite widely distributed on the north of this area. Field evidence suggests that the Ningyo-toge granite was intruded by the Okutsu granodioritic mass.
Publication Title 岡山大学温泉研究所報告
Published Date 1978-03-25
Volume volume47
Start Page 33
End Page 40
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310948
JaLCDOI 10.18926/21189
Title Alternative The involvement of ear and throat in rheumatoid arthritis I. Hearing in patients with rheumatoid arthritis
FullText URL 047_005_024.pdf
Author Oda, Rei|
Abstract Since Copeman's report on patients with hearing impairment as "rheumatoid otoarthritis?" has introduced, there have been a few reports on hearing impairment in patients with rheumatoid arthritis such as Goodwill et al. and Djupesland et aI. in European countries. On the contrary in our country there is no reference in association with hearing impairment of rheumatoid arthritis in rheumatic or otological literatures. An audiometric survey was carried out in 76 patients admitted in the Misasa branch hospital of Okayama university school of medicine on the classical or definite rheumatoid arthritis. Patients were excluded from the series if they had scarred or perforated tympanic membrane and history of otorrhea. Thus 67 patients have come to study. As control group, 15 healthy persons in hearing for each ten years, 15-24, 25-34, 35-44, 45-54, 55-64, and over 60 years, were selected and as a physiological hearing limit, rejection limit of hearingloss in dB. was made. Among 67 patients, 111 ears had hearingloss within the above mentioned rejection limit. In 23 ears, hearingloss in dB. were partial or as a whole out of the limit. They have all air-bone-conduction gap. After inflation of Eustachien tube, in most of them air conduction ability showed nearly the same level of bone conduction. In three cases even by inflation, airconduction level did not move. In one case the left side had effusion liquid and its RAreaction was positive. TwO of the former patients and the one whose effusion liquid had positive RA-test followed up for about 3 years. In the former two cases, hearing impairment got worse little by little and recovery by inflation was not seen. On both cases Gelle's test was positive. In the latter hearing impairment slowly got worse. This had lasted for about two months and had recoverd. In the se four cases heairng impairment was probably related to the rheumatoid arthritis and no other causes could be found.
Publication Title 岡山大学温泉研究所報告
Published Date 1978-03-25
Volume volume47
Start Page 5
End Page 24
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311022
JaLCDOI 10.18926/21188
Title Alternative A useful procedure for taking photograph of resected specimens
FullText URL pitsr_047_001_003.pdf
Author Noishiki, Yasuharu|
Abstract Histochemical, biochemical, and electron microscopic investigations on resected specimen have expanded in almost exponential manner in the past ten years and taking photograph of the specimens is also of importance for the examination of them. The specimens are, however, damaged during the time of taking photograph by various factors such as heat, dryness, light etc. For the investigations of this kind, the most important requirement for preservation of protoplasmic structure is to interrupt the dynamic process of the cell as prompt as possible and to stabilize the structure with a minimum of change. To prevent the damage of the specimens during the time of taking photograph, the following procedure is proposed: The specimen is dipped into cold saline solution, phosphate buffer, or cacodylate buffer. as soon as possible after operation. Photographic procedure is carried out upon the specimen dipped into the solution. By this procedure, the specimens can be protected from being damaged by heating and drying. Furthermore, the specimen can be preserved in its original shape due to the aid of buoyancy. This procedure has an another advantage : The photograph is in principle free from halation on the surface of the specimens. Thus, the proposed procedure is very useful for taking photograph of resected specimens in general.
Publication Title 岡山大学温泉研究所報告
Published Date 1978-03-25
Volume volume47
Start Page 1
End Page 3
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311000
JaLCDOI 10.18926/21181
Title Alternative A case of SLE with non-erosive joint deformity -Jaccoud's type arthropathy-
FullText URL 048_043_048.pdf
Author Tanaka, Juntaro| Domyo, Michihiro| Takasugi, Kiyoshi| Irino, Shozo| Morinaga, Hiroshi|
Abstract A case of SLE in a twenty-eight year old woman, who had polyarthritis with non-erosive joint deformity, was reported. Differential diagnosis in this case included (1) rheumatoid arthritis (2) postrheumatic fever arthritis (Jaccoud's arthritis) and (3) the overlap syndrome between SLE and rheumatoid arthritis. Laboratory findings on this patient and review on literature, however, strongly suggested that this lady had been suffering from Jaccoud's type arthropathy of SLE. Corticosteroid therapy was initiated and the clinical course of the patient thereafter has been more than favorable.
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 43
End Page 48
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40000321139
JaLCDOI 10.18926/21180
Title Alternative Determination of boron in thermal waters by emission spectrophotometry using "Spectraspan"
FullText URL pitsr_048_035_041.pdf
Author Mifune, Masaaki| Aoki, Hiroko| Tetsumoto, Junko| Furuno, Katsushi| Morinaga, Hiroshi|
Abstract A plasma emission spectrophotometer "Spectraspan" (low power d. c. plasma arc, operating on argon) was evaluated for boron determination in thermal waters. The influence of acids (hydrochloric, nitric and sulfuric acids) and several metallic ions (Na(+). K(+), Mg(2+). Ca(2+)) on emission intensity was studied. There was a linear relationship between emission intensity and boron content from 0 to 500 mg/l. Boron in thermal waters was easily determined by standard addition method. Precision. coefficient of variance and recoveries of known amount of boron added to the sample for 11 repricate analyses were 0.12μg/ml, 2.02%, 95.0-101.7%, respectively. Boron content of 27 thermal waters in the Sanin district was determined. and the highest B content in the sample waters were 8.8 mg/l (Tottori spa) in Tottori Prefecture and 14.6-25.0 mg/l (the thermal springs at the foot of Mt. Sanbe. a non-active quaternary volcano) in Shimane Prefecture. The relationships between B content and water temperature, B content and pH value were not recognized. Significantly positive correlationship was observed between Band Li contents.
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 35
End Page 41
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311017
JaLCDOI 10.18926/21179
Title Alternative Studies on sinter deposit Misasa radioactive hot springs
FullText URL pitsr_048_025_033.pdf
Author Furuno, Katsushi| Tetsumoto, Junko| Aoki, Hiroko| Mifune, Masaaki| Morinaga, Hiroshi| Fukushima, Satoru| Wada, Hiroaki|
Abstract Sinter deposit in a distributing pipe used for about fifteen years in Misasa radioactive hot springs was investigated. The results were as follows; 1. The metal elements in this deposit were quaIi. tatively analysed by spectraspan plasma emission spectrophotometry (SPES), by fluorescent X-ray spectrometry, and following elements were detected; B, Na, Mg, AI, K, Ca, Mn, Fe, Cu, Zn, As, Sr, Ba and Pb. 2. The metal elements in this deposit were quantatively analysed by SPES and atomic absorption spectrophotometry, and following elements were determined; Fe : 508.7, As: 26.40, Ca: 7.85, Mn : 2.00, Al : 1.80, Na: 1.60, Zn: 1.33, K: 0.80, Cu: 0.67, Sr: 0.47, Mg: 0.35, Ba: 0.33 and B : 0.30 mg per gram. The color of this deposit was red brown, and the main component was ferric oxide. 3. Radioactive elements in this deposit were detected by autoradiography and radioluxography. Among the radioactive elements, concentration of radium was 320.5×10(-12)g/g (313.0×10(-12)Ci/g).
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 25
End Page 33
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310949
JaLCDOI 10.18926/21178
Title Alternative Determination of copper and zinc in synovial fluid by atomic absorption spectrophotometry
FullText URL pitsr_048_013_023.pdf
Author Furuno, Katsushi|
Abstract Copper (Cu) and zinc (Zn) in synovial fluids of 52 patients with rheumatoid arthritis (RA) and of 53 patients with osteoarthritis (OA) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Standard solution of Cu and Zn were 50μg, 100μg, 200μg and 300μg per 100 ml 20 v/v % glycerine containing 0.01 N-HCl. To 0.5ml synovial fluid, 50 units of hyaluronidase was added and then the mixture were incubated for 20 minutes at 37℃. Synovial fluid treated with hyaluronidase and standard solution of Cu and Zn were diluted five fold with deionized distillation water, then aspirated directly into the burner. The relative absorbance was expressed as scale reading by a HITACHI MODEL QPD-54 recoder. The mean recovery rate of Cu and Zn in synovial fluids were 102.0% and 101.9%. By this method the concentrations of Cu and Zn in 52 RA (12 males, 40 females) were 97.6±29.0 (S.D.) μg/100 ml and 83.9±40.1 (S.D.) μg/100 ml ; 97.3±27.1 (S.D.)μg/100 ml, 78.7±29.9 (S.D.) μg /100 ml in 12males and 97.7±29.5 (S.D.) μg/100 ml, 85.5±42.6 (S.D.) μg /100 ml in 40 females respectively. The concentrations of Cu and Zn in 53 OA (14 males, 39 females) were 46.9±14.5 (S.D.) μg/100 ml and 40.8±14.3 (S.D.) μg/100 ml; 47.3±9.7 (S.D.) JLg/100 ml, 45.1±19.0 (S.D.) μg/ 100 ml in 14 males and 46.8±15.8 (S.D.) μg/100 ml, 39.3±11.8 (S.D.) μg/100 ml in 39 females respectively. No sex differences of Cu and Zn values were observed in both RA and OA. In patients with RA, concentrations of Cu and Zn in synovial fluids were signifcantly higher than in OA in both sexes. There were positive correlation between the concentrations of Cu and Zn in 105 patients (RA and OA, r=0.74, p<0.01) , in 52 RA (r=0.54, p<0.01), in 53 OA (r=0.81, p<0.01). In patients with RA, there were no correlation between stage and concentrations of Cu and Zn in synovial fluids.
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 13
End Page 23
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311026
JaLCDOI 10.18926/21176
Title Alternative Application of the ultra-thin section method for high resolution electron microscopy of clay minerals
FullText URL pitsr_048_001_006.pdf
Author Tazaki, Kazue| Noishiki, Yasuharu|
Abstract Clay mineral specimen for electron microscopy have usually been prepared by air-drying of a small drop of the suspensoin on a microgrid. The suspension method is, however, not always preferable for the observation of lattice images of clay minerals because of their preferred orientation in the air-drying process. The present writers proved that the embedding method is excellent in preservation of the nonorientated part of the crystal than that of susp, ension method. The interstratified kaolin/montmorillonite which was collected from clay bed at Itoigawa, Niigata prefecture is dehydrated progressively replacing H(2)O by ethanol, propylene oxide and Epon mixture solution and is lastly embedded in Epon 812. Ultra-thin sections are prepared with an LKB Ultratome, and are examined in a JEM-100C type electron microscope at an accelerating voltage of 100 kV. High resolution electron micrographs show lattice images reflecting irregular layer structures of kaolin and montmorillonite. Clear layer structure and lattice images can be well observed from everywhere of ultra-thin section of clay mineral (Fig. 1). Lattice images of 4.5 and 10A spacings can be observed in Fig. 2. Microstructures show some differences in spacing which emerged from combination of dehydrated montmorillonite and kaolin layers (Fig. 3).
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 1
End Page 6
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311001