result 1938 件
| JaLCDOI | 10.18926/AMO/56649 |
|---|---|
| FullText URL | 73_2_135.pdf |
| Author | Maeba, Takahiro| Yonezawa, Tomoko| Ono, Mitsuaki| Tomono, Yasuko| Heljasvaara, Ritva| Pihlajaniemi, Taina| Inagawa, Kiichi| Oohashi, Toshitaka| |
| Abstract | The basement membrane (BM) is composed of various extracellular molecules and regulates tissue regeneration and maintenance. Here, we demonstrate that collagen XVIII was spatiotemporally expressed in the BM during skin wound healing in a mouse excisional wound-splinting model. Re-epithelialization was detected at days 3 and 6 post-wounding. The ultrastructure of epidermal BM was discontinuous at day 3, whereas on day 6 a continuous BM was observed in the region proximal to the wound edge. Immunohistochemistry demonstrated that collagen XVIII was deposited in the BM zone beneath newly forming epidermis in day 3 and 6 wounds. Laminin-332, known to be the earliest BM component appearing in wounds, was colocalized with collagen XVIII in the epidermal BM zone at days 3 and 6. The deposition of α1(IV) collagen and nidogen-1 in the epidermal BM zone occurred later than that of collagen XVIII. We also observed the short isoform of collagen XVIII in the epidermal BM zone at day 3 post-wounding. Collectively, our results suggested that collagen XVIII plays a role in the formation of the dermal-epidermal junction during re-epithelialization, and that it is the short isoform that is involved in the early phase of re-epithelialization. |
| Keywords | collagen XVIII basement membrane wound healing re-epithelialization skin |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-04 |
| Volume | volume73 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 135 |
| End Page | 146 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31015748 |
| JaLCDOI | 10.18926/CTED/56543 |
|---|---|
| Title Alternative | Consideration of morality concerning "communication of the heart" : Effects of Presentation Software in Teacher Training Course Effects of Morality on Conversation Students' Conversation Form |
| FullText URL | cted_009_085_098.pdf |
| Author | Sakamoto, Kiyomi| Sakuda, Kiyokazu| Nakayama, Yoshikazu| |
| Abstract | 今日の教員への課題を取り上げ、意思疎通のあるコミュニケーションを導入した教員養成課程の必要性を検討した。なお、大学3年生(男性：10名、女性：15名)を対象として4種類の会話形態を行い、最も意思の疎通を感じ取ることのできるコミュニケーションが推認された。さらに、教職を目指す大学生を対象にして、プレゼンテーションソフトを活用した異コミュニケーションを行い、将来自分たちのえがいている教師像を目標として実施することにより、教員を志としての道徳観を抱くことが明確化された。そして、本研究における結果からこの会話形態により、道徳教育をはじめとする授業等を含めた学校教育活動全体に関わり、意思疎通による道徳性を高める効果が予測された。また、これからの倫理観と道徳観を培うための教員養成課程の在り方について明らかとした。 |
| Keywords | 目指す教師像 コミュニケーション 道徳性を深める会話形態 意思の疎通 倫理観と道徳観 |
| Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
| Published Date | 2019-03-20 |
| Volume | volume9 |
| Start Page | 85 |
| End Page | 98 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2019 岡山大学教師教育開発センター |
| File Version | publisher |
| JaLCDOI | 10.18926/AMO/56456 |
|---|---|
| FullText URL | 73_1_29.pdf |
| Author | Matsumoto, Atsushi| Nakamura, Takehiro| Shinomiya, Aya| Kawakita, Kenya| Kawanishi, Masahiko| Miyake, Keisuke| Kuroda, Yasuhiro| Keep, Richard F.| Tamiya, Takashi| |
| Abstract | Cerebral vasospasm (CVS) is a major contributor to the high morbidity and mortality of aneurysmal subarachnoid hemorrhage (aSAH) patients. We measured histidine-rich glycoprotein (HRG), a new biomarker of aSAH, in cerebrospinal fluid (CSF) to investigate whether HRG might be an early predictor of CVS. A total of seven controls and 14 aSAH patients (8 males, 6 females aged 53.4±15.4 years) were enrolled, and serial CSF and serum samples were taken. We allocated these samples to three phases (T1-T3) and measured HRG, interleukin (IL)-6, fibrinopeptide A (FpA), and 8-hydroxy-2’-deoxyguanosine (8OHdG) in the CSF, and the HRG in serum. We also examined the release of HRG in rat blood incubated in artificial CSF. In contrast to the other biomarkers examined, the change in the CSF HRG concentration was significantly different between the nonspasm and spasm groups (p<0.01). The rat blood/CSF model revealed a time course similar to that of the human CSF samples in the non-spasm group. HRG thus appears to have the potential to become an early predictor of CVS. In addition, the interaction of HRG with IL-6, FpA, and 8OHdG may form the pathology of CVS. |
| Keywords | biomarker histidine-rich glycoprotein predictor subarachnoid hemorrhage vasospasm |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-02 |
| Volume | volume73 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 29 |
| End Page | 39 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30820052 |
| reference | Sabri M, Ai J, Lakovic K and Macdonald RL: Mechanisms of microthrombosis and microcirculatory constriction after experimental subarachnoid hemorrhage. Acta Neurochir Suppl (2013) 115: 185-192.| Loch MR: Management of cerebral vasospasm. Neurosurg Rev (2006) 29: 179-193.| Vestergaard AB, Andersen HF, Magnusson S and Halkier T: Histidine-rich glycoprotein inhibits contact activation of blood coagulation. Thromb Res (1990) 60: 385-396.| MacQuarrie JL, Stafford AR, Yau JW, Leslie BA, Vu TT, Fredenburgh JC and Weitz JI: Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact initiated coagulation. Blood (2011) 117: 4134-4141.| Tsuchida-Straeten N, Ensslen S, Schafer C, Woltje M, Denecke B, Monser M, Gräber S, Wakabayashi S, Koide T and Jahnen- Dechent W: Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG). J Thromb Haemost (2005) 3: 865-872.| Poon IK, Hulett MD and Parish CR: Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via FcgammaRI on phagocytes. Blood (2010) 115: 2473-2482.| Doñate F, Juarez JC, Guan X, Shipulina NV, Plunkett ML, Tel- Tsur Z, Shaw DE, Morgan WT and Mazar AP: Peptides derived fromthe histidine-proline domain of the histidine-proline-rich glycoprotein bind to tropomyosin and have antiangiogenic and antitumor activities. Cancer Res (2004) 64: 5812-5817.| Wake H, Mori S, Liu K, Takahashi HK and Nishibori M: Histidinerich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis inmatrigel plug assay. Eur J Pharmacol (2009) 623: 89-95.| Dixelius J, Olsson AK, Thulin A, Lee C, Johansson I and Claesson-Welsh L: Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein. Cancer Res (2006) 66: 2089-2097.| Lee C, Dixelius J, Thulin A, Kawamura H, Claesson-Welsh L and Olsson AK: Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions. Exp Cell Res (2006) 312: 2547-2556.| Shannon O, Rydengård V, Schmidtchen A, Mörgelin M, Alm P, Sørensen OE and Björck L: Histidine-rich glycoprotein promotes bacterial entrapment in clots and decreases mortality in a mouse model of sepsis. Blood (2010) 116: 2365-2372.| Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H and Nishibori M: Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation. EBioMedicine (2016) 9: 180-194.| Hijdra A, Brouwers PJ, Vermeulen M and van Gijn J: Grading the amount of blood on computed tomograms after subarachnoid hemorrhage. Stroke (1990) 21: 1156-1161.| Koide T, Foster D, Yoshitake S and Davie EW: Amino acid sequence of human histidine-rich glycoprotein derived from the nucleotide sequence of its cDNA. Biochemistry (1986) 25: 2220- 2225.| Anderson GB, Ashforth R, Steinke DE and Findlay JM: CT angiography for the detection of cerebral vasospasm in patients with acute subarachnoid hemorrhage. Am J Neuroradiol (2000) 21: 1011-1015.| Brown JM, Grosso MA and Harken AH: Cytokines, sepsis and the surgeon. Surg Gynecol Obstet (1989) 169: 568-575.| Tiit M, Birger A, Annika L and Hans VH: Increased interleukin-6 levels in cerebrospinal fluid following subarachnoid hemorrhage. J Neurosurg (1993) 78: 562-567.| Chaichana KL, Pradilla G, Huang J and Tamargo RJ: Role of inflammation (leukocyte-endothelial cell interactions) in vasospasm after subarachnoid hemorrhage. World Neurosurg (2010) 73: 22- 41.| Tang QF, Lu SQ, Zhao YM and Qian JX: The changes of von willebrand factor/a disintegrin-like and metalloprotease with thrombospondin type I repeats-13 balance in aneurysmal subarachnoid hemorrhage. Int J Clin Exp Med (2015) 8: 1342-1348.| Kao HW, Lee KW, Kuo CL, Huang CS, Tseng WM, Liu CS and Lin CP: Interleukin-6 as a Prognostic Biomarker in Ruptured Intracranial Aneurysms. PLoS ONE (2015) 10: e0132115.| Fassbender K, Hodapp B, Rossol S, Bertsch T, Schmeck J, Schutt S, Fritzinger M, Horn P, Vajkoczy P, Kreisel S, Brunner J, Schmiedek P and Hennerici M: Inflammatory cytokines in subarachnoid haemorrhage: association with abnormal blood flow velocities in basal cerebral arteries. J Neurol Neurosurg Psychiatry (2001) 70: 534-537.| Niwa A, Osuka K, Nakura T, Matsuo N, Watabe T and Takayasu M: Interleukin-6, MCP-1, IP-10, and MIG are sequentially expressed in cerebrospinal fluid after subarachnoid hemorrhage. J Neuroinflammation (2016) 13: 217.| Osuka K, Watanabe Y, Yamauchi K, Nakazawa A, Usuda N, Tokuda M and Yoshida J: Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage. Brain Res (2006) 1072: 1-7.| Nakahara T, Tsuruta R, Kaneko T, Yamashita S, Fujita M, Kasaoka S, Hashiguchi T, Suzuki M, Maruyama I and Maekawa T: High-mobility group box 1 protein in CSF of patients with subarachnoid hemorrhage. Neurocrit Care (2009) 11: 362-368.| Ni W, Gu YX, Song DL, Leng B, Li PL and Mao Y: The relationship between IL-6 in CSF and occurrence of vasospasm after subarachnoid hemorrhage. Acta Neurochir Suppl (2011) 110: 203- 208.| Osuka K, Suzuki Y, Tanazawa T, Hattori K, Yamamoto N, Takayasu M, Shibuya M and Yoshida J: Interleukin-6 and development of vasospasm after subarachnoid haemorrhage. Acta Neurochir (Wien) (1998) 140: 943-951.| Blomback B: Fibrinogen and fibrin-proteins with complex roles in hemostasis and thrombosis. Thromb Res (1996) 83: 1-75.| Weisel JW: Fibrin assembly. Lateral aggregation and the role of the 2 pairs of fibrinopeptides. Biophys J (1986) 50: 1079-1093.| Weisel JW, Veklich Y and Gorkun O: The sequence of cleavage of fibrinopeptides from fibrinogen is important for protofibril formation and enhancement of lateral aggregation in fibrin clots. J Mol Biol (1993) 232: 285-297.| Yong JI, Meng QH and Wang ZG: Changes in the coagulation and fibrinolytic system of patients with subarachnoid hemorrhage. Neurol Med Chir (Tokyo) (2014) 54: 457-464.| Kasuya H: Complement components in cerebrospinal fluid and vasospasm after subarachnoid hemorrhage. Journal Tokyo Womanʼs Medical University (1990) 60: 63-68 (in Japanese).| Kasuya H, Shimizu T, Okada T, Takahashi K, Summerville T and Kitamura K: Activation of the coagulation system in the subarachnoid space after subarachnoid hemorrhage: Serial measurement of fibrinopeptide A and bradykinin of cerebrospinal fluid and plasma in patients with subarachnoid hemorrhage. Acta Neurochir (1988) 38 Matsumoto et al. Acta Med. Okayama Vol. 73, No. 1 91: 120-125.| Blat Y and Seiffert D: A renaissance for the contact system in blood coagulation? Thromb Haemost (2008) 99: 457-460.| Colman RW: Are hemostasis and thrombosis two sides of the same coin? J Exp Med (2006) 203: 493-495.| Kasai H: Analysis of a form of oxidative DNA damage, 8-hydroxy-2ʼ-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res (1997) 387: 147-163.| Lunec J, Holloway KA, Cooke MS, Steve F, Helen RG and Mark DE: Urinary 8-oxo2ʼ-deoxyguanosine: redox regulation of DNA repair in vivo? Free Radic Biol Med (2002) 33: 875-885.| Ayer RE and Zhang JH: Oxidative stress in subarachnoid haemorrhage: significance in acute brain injury and vasospasm. Acta Neurochir (Suppl) (2008) 104: 33-41.| Zhao M, Ikeda Y, Jimbo H, Fukuda A, Sugiyama K, Ishihara K and Matsumoto K: The correlation between DNA damage and cell membrane damage based on the analysis of the new oxidative stress marker in patients with subarachnoid hemorrhage. J Showa Univ Soc (2002) 62: 50-56 (in Japanese).| Mori T, Nagata K, Town T, Tan J, Matsui T and Asano T: Intracisternal increase of superoxide anion production in a canine subarachnoid hemorrhage model. Stroke (2001) 32: 636-642.| Steelman SM, Hein TW, Gorman A and Bix GJ: Effects of histidine- rich glycoprotein on cerebral blood vessels. J Cereb Blood Flow Metab (2013) 33: 1373-1375.| Leung LL, Harpel PC, Nachman RL and Rabellino EM: Histidinerich glycoprotein is present in human platelets and is released following thrombin stimulation. Blood (1983) 62: 1016-1021.| Blank M and Shoenfeld Y: Histidine-rich glycoprotein modulation of immune/autoimmune, vascular, and coagulation systems. Clin Rev Allergy Immunol (2008) 34: 307-312.| |
| FullText URL | OJE_2019021915240510.pdf |
|---|---|
| Author | Kato, Sadahisa| Hishiyama, Kosuke| Anak Agung Ketut Darmadi| Ngakan Ketut Acwin Dwijendra| Dewa Ngurah Suprapta| |
| Keywords | Telajakan Bali Urban Green Spaces |
| Published Date | 2019-02-20 |
| Publication Title | Open Journal of Ecology |
| Volume | volume9 |
| Publisher | Scientific Research Publishing |
| Start Page | 15 |
| End Page | 24 |
| ISSN | 2162-1993 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | http://creativecommons.org/licenses/by/4.0/ |
| File Version | publisher |
| DOI | 10.4236/oje.2019.92002 |
| Related Url | isVersionOf https://doi.org/10.4236/oje.2019.92002 |
| Title Alternative | Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus Species |
|---|---|
| FullText URL | srfa_108_001_004.pdf |
| Author | Kiyota, Hiromasa| Saito, Akihito| Takai, Momoko| Kuwahara, Shigefumi| |
| Abstract | Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus sp., are described. Buchwald‒Hartwig coupling reaction between the dihydroisoquinoline and the naphthyl triflate failed. The main framework of ancistrocladinium A was constructed by 1,2‒addition of the amine to the naphthoquinone in the presence of celium trichloride as a catalyst. On the other hand, 1,4‒addition of the amine to the naphthoquinone proceeded without catalyst to form the framework of B. These products will be valuable leads for antileishmanial agents. |
| Keywords | ancistrocladinium A and B synthetic studies leishmania, Ancistrocladus isoquinoline |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2019-02-01 |
| Volume | volume108 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| JaLCDOI | 10.18926/56349 |
|---|---|
| Title Alternative | On the Description of the Adjective -ku Form in Japanese Language Dictionaries and Word List by Semantic Principles, Revised and Enlarged Edition |
| FullText URL | hss_046_125_141.pdf |
| Author | Kato, Kazumi| |
| Publication Title | Journal of Humanities and Social Sciences |
| Published Date | 2018-11-26 |
| Volume | volume46 |
| Start Page | 125 |
| End Page | 141 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2018 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120006540166 |
| JaLCDOI | 10.18926/56348 |
|---|---|
| Title Alternative | How Advanced Learners of Japanese Manage the Use of Non-Finite Forms of Verbs : Analysis of Relational Meanings in Predications |
| FullText URL | hss_046_107_123.pdf |
| Author | Miyazaki, Satoko| |
| Publication Title | Journal of Humanities and Social Sciences |
| Published Date | 2018-11-26 |
| Volume | volume46 |
| Start Page | 107 |
| End Page | 123 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2018 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120006540165 |
| JaLCDOI | 10.18926/56346 |
|---|---|
| Title Alternative | On Complex Sentences Formed by ima |
| FullText URL | hss_046_073_091.pdf |
| Author | Ma, Xiaofei| |
| Publication Title | Journal of Humanities and Social Sciences |
| Published Date | 2018-11-26 |
| Volume | volume46 |
| Start Page | 73 |
| End Page | 91 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2018 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120006540163 |
| JaLCDOI | 10.18926/56341 |
|---|---|
| Title Alternative | Toward a J-Form Theory of Knowledge-Creating Firms |
| FullText URL | hss_046_001_011.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Journal of Humanities and Social Sciences |
| Published Date | 2018-11-26 |
| Volume | volume46 |
| Start Page | 1 |
| End Page | 11 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2018 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120006540158 |
| FullText URL | mjou_061_075_084.pdf |
|---|---|
| Author | Izadi, Farzali| Baghalaghdam, Mehdi| |
| Keywords | Diophantine equations Cubes Quintics Elliptic curves Rank |
| Published Date | 2019-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume61 |
| Issue | issue1 |
| Publisher | Department of Mathematics, Faculty of Science, Okayama University |
| Start Page | 75 |
| End Page | 84 |
| ISSN | 0030-1566 |
| NCID | AA00723502 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright©2019 by the Editorial Board of Mathematical Journal of Okayama University |
| FullText URL | Nature_556_209.pdf |
|---|---|
| Author | Yu, Long-Jiang| Suga, Michihiro| Wang-Otomo, Zheng-Yu| Shen, Jian-Ren| |
| Note | This is an Accepted Manuscript of an article published by Springer Nature| |
| Published Date | 2018-04-04 |
| Publication Title | Nature |
| Volume | volume556 |
| Publisher | Springer Nature |
| Start Page | 209 |
| End Page | 213 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 29618814 |
| DOI | 10.1038/s41586-018-0002-9 |
| Web of Science KeyUT | 000430082000040 |
| Related Url | isVersionOf https://doi.org/10.1038/s41586-018-0002-9 |
| FullText URL | PhysRevB_97_104503.pdf |
|---|---|
| Author | He, Tong| Yang, Xiaofan| Terao, Takahiro| Uchiyama, Takaki| Ueno, Teppei| Kobayashi, Kaya| Akimitsu, Jun| Miyazaki, Takafumi| Nishioka, Takumi| Kimura, Koji| Hayashi, Kouichi| Happo, Naohisa| Yamaoka, Hitoshi| Ishii, Hirofumi| Liao, Yen-Fa| Ota, Hiromi| Goto, Hidenori| Kubozono, Yoshihiro| |
| Note | This is an article published by American Physical Society| This study was partly supported by Grants-in-Aid (Grants No. 26105004 and No. 17K05500) from MEXT, by JST ACT-C Grant No. JPMJCR12YW| |
| Published Date | 2018-03-07 |
| Publication Title | Physical Review B |
| Volume | volume97 |
| Issue | issue10 |
| Publisher | American Physical Society |
| Start Page | 104503 |
| ISSN | 01631829 |
| NCID | AA11187113 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1103/PhysRevB.97.104503 |
| Web of Science KeyUT | 000426776800003 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevB.97.104503 |
| FullText URL | PhysRevB_97_094505.pdf |
|---|---|
| Author | Terao, Takahiro| Yang, Xiaofan| Miao, Xiao| Zheng, Lu| Goto, Hidenori| Miyazaki, Takafumi| Yamaoka, Hitoshi| Ishii, Hirofumi| Liao, Yen-Fa| Kubozono, Yoshihiro| |
| Keywords | Superconductors 2-dimensional systems 4-terminal techniques Pressure effects X-ray diffraction |
| Note | This is an article published by American Physical Society| This study was partly supported by Grants-in-Aid (26105004 and 26400361) from MEXT, by JST ACT-C Grant No. JPMJCR12YW, Japan, and by the Program for Promoting the Enhancement of Research Universities.| |
| Published Date | 2018-03-09 |
| Publication Title | Physical Review B |
| Volume | volume97 |
| Issue | issue9 |
| Publisher | American Physical Society |
| Start Page | 094505 |
| ISSN | 01631829 |
| NCID | AA11187113 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1103/PhysRevB.97.094505 |
| Web of Science KeyUT | 000427010000003 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevB.97.094505 |
| FullText URL | elife_7_30246.pdf |
|---|---|
| Author | Takeda, Tetsuya| Kozai, Toshiya| Yang, Huiran| Ishikuro, Daiki| Seyama, Kaho| Kumagai, Yusuke| Abe, Tadashi| Yamada, Hiroshi| Uchihashi, Takayuki| Ando, Toshio| Takei, Kohji| |
| Keywords | EM HS-AFM amphiphysin biophysics cell biology dynamin human in vitro reconstitution membrane remodeling structural biology |
| Published Date | 2018-01 |
| Publication Title | eLife |
| Volume | volume7 |
| Publisher | eLife Sciences Publications |
| Start Page | e30246 |
| ISSN | 2050-084X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 29357276 |
| DOI | 10.7554/eLife.30246 |
| Web of Science KeyUT | 000423036500001 |
| Related Url | isVersionOf https://doi.org/10.7554/eLife.30246 |
| JaLCDOI | 10.18926/AMO/56169 |
|---|---|
| FullText URL | 72_4_343.pdf |
| Author | Nishie, Hiroyuki| Tetsunaga, Tomoko| Kanzaki, Hirotaka| Oda, Koji| Inoue, Shinichiro| Ryuo, Yuta| Ota, Haruyuki| Miyawaki, Takuya| Arakawa, Kyosuke| Tetsunaga, Tomonori| Kitamura, Yoshihisa| Sendo, Toshiaki| Morimatsu, Hiroshi| Ozaki, Toshifumi| Nishida, Keiichiro| |
| Abstract | We conducted this study to determine the short-term treatment outcomes of multidisciplinary approaches to chronic pain management for outpatients in Japan. We evaluated pain reduction and improvement in quality of life (QOL) after treatment. We analyzed 32 patients who had experienced intractable chronic pain for > 3 months. The patients received multidisciplinary therapeutic self-managed exercise instructions and then underwent evaluations 1 and 3 months after the treatment. We used the Pain Disability Short Form-36 (SF-36), Pain Catastrophizing Scale (PCS), and Pain Disability Assessment Scale (PDAS) to evaluate QOL. Although the pain levels were the same before and after the physical exercise program, the patients showed significant improvements in physical function on the SF-36 (48.5 vs. 54.5, 3 months vs. 1 month; p=0.0124), the magnification subscale on the PCS (6.8 vs. 5.9, 1 month vs. before; p=0.0164) and the PDAS (29.2 vs. 23.4, 3 months vs. before; p=0.0055). Chronic pain should be treated with a biopsychosocial approach, but time constraints and costs have limited the implementation of multidisciplinary and behavioral approaches to chronic pain management. Our findings demonstrate that clinical improvements are possible for patients with chronic pain, using multidisciplinary team resources widely available in Japanese clinical practice. |
| Keywords | multidisciplinary treatment pain management quality of life biopsychosocial approach chronic pain |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 343 |
| End Page | 350 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140081 |
| Title Alternative | Periodical structure of vortices in a semiconductor single wafer spin cleaner |
|---|---|
| FullText URL | TransJSME_81_829_2015.pdf |
| Author | KOUCHI, Toshinori| FUKUDA, Naoya| NAKANO, Yusuke| SHIMIZU, Yoshiya| NAGATA, Yasunori| YANASE, Shinichiro| |
| Keywords | Rotating disk Flow stability Large-scale structure PIV LES |
| Published Date | 2015 |
| Publication Title | Transactions of the JSME |
| Volume | volume81 |
| Issue | issue829 |
| Publisher | 日本機械学会 |
| Start Page | 15-00273 |
| ISSN | 00290270 |
| NCID | AN00187419 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2015 The Japan Society of Mechanical Engineers |
| File Version | author |
| DOI | 10.1299/transjsme.15-00273 |
| Related Url | isVersionOf https://doi.org/10.1299/transjsme.15-00273 |
| FullText URL | PlosOne_2018_e0191109.pdf |
|---|---|
| Author | Eguchi, Takanori| Sogawa, Chiharu| Okusha, Yuka| Uchibe, Kenta| Iinuma, Ryosuke| Ono, Kisho| Nakano, Keisuke| Murakami, Jun| Itoh, Manabu| Arai, Kazuya| Fujiwara, Toshifumi| Namba, Yuri| Murata, Yoshiki| Ohyama, Kazumi| Shimomura, Manami| Okamura, Hirohiko| Takigawa, Masaharu| Nakatsura, Tetsuya| Kozaki, Kenichi| Okamoto, Kuniaki| Calderwood, Stuart K.| |
| Published Date | 2018-02-07 |
| Publication Title | PlosOne |
| Volume | volume13 |
| Issue | issue2 |
| Publisher | Public Library Science |
| Start Page | e0191109 |
| ISSN | 19326203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 29415026 |
| DOI | 10.1371/journal.pone.0191109 |
| Web of Science KeyUT | 000424325300015 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0191109 |
| JaLCDOI | 10.18926/AMO/56076 |
|---|---|
| FullText URL | 72_3_297.pdf |
| Author | Yamamoto, Hirotsugu| Naito, Hiromichi| Osako, Takaaki| Tsukahara, Kohei| Yamada, Taihei| Yumoto, Tetsuya| Iida, Atsuyoshi| Kosaki, Yoshinori| Oka, Makio| Endo, Fumika| Gochi, Akira| Nakao, Atsunori| |
| Abstract | A healthy 10-year-old boy vomited during sleep and later complained of abdominal pain; he became drowsy and uncommunicative. At the nearby hospital E.R., he deteriorated rapidly, and his respiratory movements were absent with cardiac arrest. He was immediately resuscitated. Brain MRI showed no abnormalities. EEG revealed an abnormal pattern with recurrent multifocal epileptiform activity over the bilateral occipital and frontal regions during sleep. Based on the clinical/radiological findings we diagnosed Panayiotopoulos syndrome (PS), a benign form of early-onset pediatric epilepsy characterized by autonomic symptoms. Lifethreating cardiopulmonary arrest is rare in PS, but long seizure duration of PS may associate with apnea and bradycardia. |
| Keywords | pediatric epilepsy autonomic symptom cardiac arrest afebrile seizure EEG |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-06 |
| Volume | volume72 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 297 |
| End Page | 300 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29926008 |
| FullText URL | PlosOne_2016_e0162394.PDF |
|---|---|
| Author | Arai, Kazuya| Eguchi, Takanori| Rahman, M. Mamunur| Sakamoto, Ruriko| Masuda, Norio| Nakatsura, Tetsuya| Calderwood, Stuart K.| Kozaki, Ken-ichi| Itoh, Manabu| |
| Published Date | 2016-09-13 |
| Publication Title | PLoS One |
| Volume | volume11 |
| Issue | issue9 |
| Publisher | Public Library of Science |
| Start Page | e0162394 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 27622654 |
| DOI | 10.1371/journal.pone.0162394 |
| Web of Science KeyUT | 000383681000029 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0162394 |
| Title Alternative | Avian coccidiosis : Toward the understanding of pathophysiology in Eimeria tenella infection |
|---|---|
| FullText URL | poalas_034_017.pdf |
| Author | Hatabu, Toshimitsu| |
| Abstract | Avian coccidiosis is most important entero-parasitic disease in the world. Eimeria parasite is causative agent of this disease. In Japan, this parasite species were widely spread and the positive rates are about 50 in layer and 70 % in broiler. The symptoms of coccidiosis are diarrhea, bloody excretion, weight loss, and die. Eimeria tenella is the most pathogenic protozoa. The sporozoites, infection form of this parasite, entry to epithelial cells around the crypt of cecum in early infection. After infection, parasites proliferate in epithelial cells, and form to sexual stage finally. However, we have less information about the pathophysiology, especially invasive mechanisms and infection route, by E. tenella infection. We have focused to analyze the invasive mechanism and route of this parasite because this phenomenon is first event to cause the pathophysiological changes in the infection. I would like to inform about Eimeria parasite and introduce our research in this paper. |
| Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
| Published Date | 2018-04 |
| Volume | volume34 |
| Start Page | 17 |
| End Page | 20 |
| language | Japanese |
| File Version | publisher |
