result 47530 件
| Author | 吉岡 伸一| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14981 |
| Author | 金 錦萍| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14980 |
| JaLCDOI | 10.18926/14979 |
|---|---|
| Title Alternative | 気管支喘息症例における臨床的特徴と鼻腔･副鼻腔のCT所見の関連について |
| FullText URL | 068_034_040.pdf |
| Author | Mifune, Takashi| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine| |
| Abstract | Extent of nasal and maxillary mucosa lesion was estimated in 26 asthmatics using computed tomographic scan in relation to clinical features of the disease. 1. No significant differences were present in nasal mucosal thickening between atopic and non-atopic subjects. No significant differences were also present in occupancy rate of mucosa in maxillary sinuses between the two asthma types. 2. Nasal mucosal thickening was not significant different between subjects with steroid-dependent intractable asthma (SDIA) and those without SDIA. Maxillary mucosal lesions were more extensive in subjects with SDIA than in those without SOIA. However, no significant differences were observed in occupancy rate between the two types. 3. No significant differences were observed in nasal mucosal thickenings between in subjects with and without aspirin-induced asthma (AlA). Although maxillary mucosa lesion in subjects with AlA was more extensive than that in those without AlA, the differences was not significant. 4. There was not any correlation between nasal mucosal thickening and amount of expectoration per day. However, significant differences were observed in maxillary sinus lesion between subjects with less amount (<50mℓ/day) and those with large amount of expectoration (100mℓ/day≦)(p<0.002), and between subjects with moderate amount (50-99mℓ/ day) and those with large amount of expectoration (p<0.002). The results might suggest that in asthmatics with large amount of expectoration, sinus diseases affect pathophysiology of asthma, and asthmatics with large amount of expectoration should have therapy for sinus disease to improve asthmatic status. |
| Keywords | bronchial asthma sinusitis nasal disease CT scan expectoration |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 34 |
| End Page | 40 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308538 |
| JaLCDOI | 10.18926/14978 |
|---|---|
| Title Alternative | Effect of spa therapy on peak expiratory flow in patients with bronchial asthma |
| FullText URL | 068_028_033.pdf |
| Author | Mifune, Takashi| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine| |
| Abstract | 気管支喘息に対する温泉療法の効果をピークフローメーターを用いて継時的(第1週,第5過,第9週)に検討した｡1.軽症･中等症では,第5週で有意にピークフロー (PEF)値は上昇した.重症気管支喘息例では第9週に有意な改善を認めた｡2.20%以上のPEF値の改善を認めた症例の割合は第5週では,軽症･中等症･重症群で40～50%であったが,第9週では軽症群で80%,重症群で54.5%に増加していた｡中等症群では第5週と同等であった｡3.第1週のPEFが200(L/m)以下の症例では第5週,第9過とPEFの有意な改善を示したが,200 |
| Keywords | bronchial asthma spa therapy peak expiratory flow (PEF) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 28 |
| End Page | 33 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308119 |
| Author | 楼 建波| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14977 |
| Author | 荒木 勝| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14976 |
| JaLCDOI | 10.18926/14975 |
|---|---|
| Title Alternative | 気管支喘息におけるHRCTによるLow attenuation area(LAA)と平均CT numberとの関連 |
| FullText URL | 068_015_021.pdf |
| Author | Mitsunobu, Fumihiro| Ashida, Kozo| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Tanizaki, Yoshiro| Nakai, Mutsuo| Akiyama, Tsuneo| Hasegawa, Harumi| |
| Abstract | The maximal percent low attenuation area < -950 HU (% LAA) among three anatomic lung levels on high resolution computed tomography (HRCT) was examined in patients with asthma, classified by the degree of % LAA, in relation to the mean CT number, % FVC of the predicted value, and FEV 1/FVC (FEV1%). 1 . The mean CT number was closely related to the degree of % LAA of the lungs. The mean CT number was significantly lower in patients with high % LAA (mean CT number-915.3HU, % LAA 37.6%) than in those with low % LAA (-852.9HU, 4.7%). 2. The FEV1% value was significantly lower in patients with high % LAA (47.8%) than in those with low % LAA (62.2%)(p<0.05). The % FVC value was also significantly lower in patients with high % LAA (77.1%) compared to the value in those with low % LAA (101.2%). The results suggest that a large volume of LAA<-950HU of the lungs can be observed in patients with asthma, and the % LAA is closely correlated with mean CT number and the values of FEV1% and % FVC. |
| Keywords | bronchial asthma % LAA mean CT number FEV1 FVC |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 15 |
| End Page | 21 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308351 |
| JaLCDOI | 10.18926/14974 |
|---|---|
| Title Alternative | 気管支喘息におけるCTによる気腫性変化｡喫煙症例と非喫煙症例の比較｡ |
| FullText URL | 068_008_014.pdf |
| Author | Tanizaki, Yoshiro| Mitsunobu, Fumihiro| Ashida, Kozo| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Nakai, Mutsuo| Akiyama, Tsuneo| |
| Abstract | The percentage of attenuation area < -950HU (% LAA) on high resolution computed tomography (HRCT) was compared between 17 smoking and 24 nonsmoking patients with asthma. 1. FEV1/FVC value was lower in smoking patients (56.4%) than in nonsmoking patients (66.0%), however, the difference was not significant. 2. The percentage of LAA of the lung was larger in smoking patients compared with that in nonsmoking patients in all the three anatomic levels: the % LAA was 14.4% in nonsmoking and 20.3% in smoking patients at lower lung level (3cm above the top of the diaphragm). However, this was not significant. The maximal % LAA among the three lung levels on HRCT was 21.6±12.5% in smoking, and 15.7±11.9% in nonsmoking patients. This suggested that the maximal % LAA was larger in smoking patients, however, this was not significant. 3. The mean CT number of the lung on HRCT was smaller in smoking patients (-897.3HU) than in nonsmoking patients (-884.7HU). 4. Three of 4 nonsmoking patients whose % LAA was more than 30% had severe intractable asthma with long-term glucocorticoid therapy. The results suggest the possibility that smoking influences the % LAA of the lung on HRCT in asthma. It could be also speculated that % LAA is influenced by severity of asthma. |
| Keywords | bronchial asthma FEV1 % LAA mean CT number HRCT |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 8 |
| End Page | 14 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308579 |
| JaLCDOI | 10.18926/14973 |
|---|---|
| Title Alternative | Clinical significance of spa therapy in the treatment of patients with chronic obstructive pulmonary disease (COPD). A study on 520 patients with COPD admitted for last5 years. |
| FullText URL | 068_001_007.pdf |
| Author | Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Iwagaki, Naofumi| Yamamoto, Kazuhiko| |
| Abstract | 1992年1月より1996年12月までの5力年間に当院へ入院した慢性閉塞性呼吸器疾患520例を対象に,疾患の種類,年齢,地域分布などについて検討を加えた｡1.最近5年間に当院へ入院した呼吸器疾患患者は588例で,このうち,慢性閉塞性呼吸器疾患患者は520例(88.4%)であった｡これらの慢性閉塞性呼吸器疾患のなかでは,気管支喘息が433例(83.3%)と最も多く,その他,慢性気管支炎19例,閉塞性細気管支炎33例,肺気腫35例であった｡2.慢性閉塞性呼吸器疾患の年齢別検討では,鳥取県内および遠隔地(鳥取県外)いずれの症例においても,60-69才および70才以上の症例が多い傾向が見られた｡3.入院患者の地域分布では,鳥取県内からの入院患者に比べ,遠隔地(鳥取県外)からの入院患者がより多く,その分布別検討では,岡山県,兵庫県,大阪腐,広島県,山口県,愛媛県からの入院患者が多い傾向が見られた｡ |
| Keywords | 慢性閉塞性呼吸器疾患 (COPD) 気管支喘息 (bronchial asthma) 温泉療法 (spa therapy) 高齢患者 (aged patients) 遠隔地 (distant area) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 1 |
| End Page | 7 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308043 |
| JaLCDOI | 10.18926/14972 |
|---|---|
| Title Alternative | 気管支喘息におけるアレルギー性鼻炎と花粉抗原に対するIgE抗体 |
| FullText URL | 068_022_027.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | IgE antibodies against inhalant allergens were estimated in 53 patients with bronchial asthma in relation to allergic rhinitis. Of them, 20 patients (37.7%) had allergic rhinitis. 1. Asthma + allergic rhinitis were often observed in patients between the ages of 0 and 39. In contrast, asthma alone in those over age 60. 2. A RAST score was positive in house dust mite (HDm)(50.9%), cockroach(24.5%), and Candida (26.4%) in these patients, and the positive rate was not different between patients with and without allergic rhinitis. 3. The frequency of positive RAST against Japanese cedar and rice plants was higher in patients with allergic rhinitis (42.9% and 18.5%) than in those without allergic rhinitis (28.6 and 3.7%), however, the each positive rate or RAST against the two allergens was not significantly different between those with AR and without AR. 4. The number of patients with AR induced by pollen alone (pollinosis) was not large ( 5/53, 9.4%) in the patients with asthma. It was clarified from the results that allergic rhinitis was often observed in asthma patients, but not pollinosis. and that IgE antibodies against Japanese cedar and rice plants were found even in patients without AR. |
| Keywords | bronchial asthma allergic rhinitis IgE antibodies house dust mite Japanese cedar |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1997-12 |
| Volume | volume68 |
| Start Page | 22 |
| End Page | 27 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308327 |
| Author | 岡山大学医学部附属病院三朝分院| |
|---|---|
| Published Date | 1998-12 |
| Publication Title | 岡大三朝分院研究報告 |
| Volume | volume69 |
| Content Type | Others |
| Author | Matsubara, Fumie| Inoue, Taeko| Mitsunobu, Yasuko| Mifune, Takashi| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 1998-12 |
| Publication Title | 岡大三朝分院研究報告 |
| Volume | volume69 |
| Content Type | Data or Dataset |
| Author | 岡山大学医学部附属病院三朝分院看護部| |
|---|---|
| Published Date | 1998-12 |
| Publication Title | 岡大三朝分院研究報告 |
| Volume | volume69 |
| Content Type | Others |
| JaLCDOI | 10.18926/14968 |
|---|---|
| FullText URL | 069_088_092.pdf |
| Author | 土海 智穂| Terasaki, Kayo| 岡本 和代| 山田 修子| |
| Abstract | 関節の変形と骨破壊を伴い,排泄動作に支障をきたしている慢性関節リウマチ患者に対し改良パンツの作成を試みた｡残存機能に合わせはきなれたパンツを=夫することにより,排泄動作が自立でき満足感が得られた｡ |
| Keywords | 慢性関節リウマチ 改良衣類 排泄自立 満足感 |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 88 |
| End Page | 92 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308379 |
| Author | 徐 裕卿| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14967 |
| Author | 張 東震| |
|---|---|
| Published Date | 2007-03-31 |
| Publication Title | 文化共生学研究 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/14966 |
| JaLCDOI | 10.18926/14965 |
|---|---|
| Title Alternative | 膵癌における癌遺伝子および癌抑制遺伝子 |
| FullText URL | 069_082_087.pdf |
| Author | Ochi, Koji| Matsumura, Naoki| Ichimura, Mitsuko| Mizushima, Takaaki| Harada, Hideo| Hasuoka, Hideaki| Yokoyama, Motohiro| Tsurumi, Tetsuya| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| |
| Abstract | Recent advances in molecular biology have revealed that a number of oncogenes (K-ras, erbB-2, and Met) and tumor suppressor genes (p53, p16, APC, and DCC) contribute to the development of pancreatic cancer. This paper reviewed the present knowledge of oncogenes and tumor suppressor genes relevant to pancreatic cancer. Further studies on molecular alterations in pancreatic cancer may lead to a better understanding of tumor biology, offering a possibility of development of new diagnostic and therapeutic approaches in the future. |
| Keywords | Pancreatic cancer oncogene tumor suppressor gene genetic mutation |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 82 |
| End Page | 87 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308547 |
| JaLCDOI | 10.18926/14964 |
|---|---|
| Title Alternative | The effects of perilla seed oil ointment for atopic dermatitis |
| FullText URL | 069_076_081.pdf |
| Author | Miyamoto, Miyuki| Akiyama, Chiaki| Noumi, Michiyo| Takata, Junko| Nisimura, Nobuko| Nakamura, Sumie| Kawakami, Yasuhiro| Okamoto, Makoto| Ashida, Kozo| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| |
| Abstract | 近年アトピー性皮膚炎が増加しており,工ゴマ油を使った食事療法がアレルギー抑制に有用であることが報告されている｡そこで今回,エゴマ油を外用剤として使用するため,亜鉛華単軟膏を基剤とした工コマ軟膏を作製し,アトピー性皮膚炎患者3例を対象にその臨床応用を試みた｡その結果,掻痒感の軽減に効果がみられ,また皮膚症状では,丘疹.表皮剥離,苔癬化,落屑などの所見が改善される傾向が見られた｡ |
| Keywords | アトピー性皮膚炎 エゴマ軟膏 掻痒感 |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 76 |
| End Page | 81 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308418 |
| JaLCDOI | 10.18926/14963 |
|---|---|
| Title Alternative | サーモグラフィーによる体表面温度の測定 2.温水負荷の効果 |
| FullText URL | 069_068_075.pdf |
| Author | Hosaki, Yasuhiro| Takata, Shingo| Mitsunobu, Fumihiro| Mifune, Takashi| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Harada, Seishi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| Tsuji, Takao| |
| Abstract | The body surface temperature of 41 patients suffering coldness, numbness or pain in their feet was examined using thermography. Thermographic results were analyzed quantitatively by calculating a recovery ratio as: Recovery ratio =[Total counts of thermography (Pixels) over temperature (T) after cold loading] ÷ [Initial counts over T before cold loading] x 100(%). Three different baseline temperatures, 26℃. 27℃ and 28℃, were used in processing the thermographic results into pictures. The recovery ratio was susceptible to temperature, and we recommend a baseline temperature limitation of 27℃ for clinical study. A bi-modal distribution of recovery ratio was observed in 18 patients with diabetes mellitus. One group (6 subjects) had high recovery ratio between 80%-100%, and another group (10 subjects) had a low recovery ratio between 0%-19%. The results of thermography were also influenced by weather. To reduce the effect of outside temperature, we used pre-loading with hot water at 36℃ for 5 min (hot loading). A large difference in recovery ratio between presence and absence of hot loading was observed in 6 of the 30 subjects. The difference was over-estimated in more than 20% of recovery ratio without hot loading as compared with hot loading in these 6 subjects. The effect of drugs on peripheral circulation, such as beraprost sodium and sarpogrelate hydrochloride, was clear and quantified using thermography under these conditions of hot loading. |
| Keywords | サーモグラフィー (thermography) 糖尿病 (diabetes mellitus) 末梢循環 (peripheral circulation) 冷水負荷 (cold loading) 温水負荷 (hot loading) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 68 |
| End Page | 75 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308316 |
| JaLCDOI | 10.18926/14962 |
|---|---|
| Title Alternative | ステロイド依存性重症難治性気管支喘息症例における胃粘膜病変の検討 |
| FullText URL | 069_063_067.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Harada, Seishi| Okamoto, Makoto| Yumoto, Eiichirou| Takata, Shingo| Tanizaki, Yoshiro| |
| Abstract | Recently, we experienced two asthmatic patients with advanced gastric cancer. The two patients had steroid-dependent intractable asthma (SDIA) who had been on administration of corticosteroids for more than 2 years. To determine the influence of pathophysiology of SDIA on stomach mucous lesion, gastroscopic examinations and immunological examinations were performed in eight patients with SDIA, compared with 25 patient with non-SDIA. In patients with SDIA, gastric cancer, its precursor condition and immunosuppressive state were observed. These results suggest that the immunosuppressive state in SDIA induced by the long-term administration of corticosteroids may lead to the risk of gastric cancer development. |
| Keywords | ステロイド依存性重症難治性 (steroid-dependent intractable asthma (SDIA)) 胃癌 (gastric cancer) 免疫抑制 (immunosuppression) リンパ球 (lymphocytes) IgG |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 63 |
| End Page | 67 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308665 |
