result 47501 件
| JaLCDOI | 10.18926/AMO/68354 |
|---|---|
| FullText URL | 79_1_009.pdf |
| Author | Ikeya, Nanami| Okita, Atsushi| Hashida, Shinsuke| Yamamoto, Sumiharu| Ikeda, Hirokuni| Tsukuda, Kazunori| Toyooka, Shinichi| |
| Abstract | Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy. |
| Keywords | sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-02 |
| Volume | volume79 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 9 |
| End Page | 19 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40012155 |
| Web of Science KeyUT | 001440463800002 |
| JaLCDOI | 10.18926/AMO/68353 |
|---|---|
| FullText URL | 79_1_001.pdf |
| Author | Thiha, Moe| Hikita, Takao| Nakayama, Masanori| |
| Abstract | Endothelial cell polarity is fundamental to the organization and function of blood vessels, influencing processes such as angiogenesis, vascular stability, and response to shear stress. This review elaborates on the molecular mechanisms that regulate endothelial cell polarity, focusing on key players like the PAR polarity complex and Rho family GTPases. These pathways coordinate the front–rear, apical–basal and planar polarity of endothelial cells, which are essential for the proper formation and maintenance of vascular structures. In health, endothelial polarity ensures not only the orderly development of blood vessels, with tip cells adopting distinct polarities during angiogenesis, but also ensures proper vascular integrity and function. In disease states, however, disruptions in polarity contribute to pathologies such as coronary artery disease, where altered planar polarity exacerbates atherosclerosis, and cancer, where disrupted polarity in tumor vasculature leads to abnormal vessel growth and function. Understanding cell polarity and its disruption is fundamental not only to comprehending how cells interact with their microenvironment and organize themselves into complex, organ-specific tissues but also to developing novel, targeted, and therapeutic strategies for a range of diseases, from cardiovascular disorders to malignancies, ultimately improving patient outcomes. |
| Keywords | blood vessel endothelial cell cell polarity atherosclerosis cancer |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-02 |
| Volume | volume79 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 7 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40012154 |
| Web of Science KeyUT | 001440463800001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kono, Reika| Hamasaki, Ichiro| Kishimoto, Fumiko| Shibata, Kiyo| Morisawa, Shin| Morizane, Yuki| |
| Keywords | Orbital pulley Sagging eye syndrome Distance esotropia Cyclovertical strabismus Aging |
| Note | The version of record of this article, first published in Japanese Journal of Ophthalmology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10384-024-01141-8| |
| Published Date | 2025-02-04 |
| Publication Title | Japanese Journal of Ophthalmology |
| Volume | volume69 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1 |
| End Page | 9 |
| ISSN | 0021-5155 |
| NCID | AA00691177 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 39903417 |
| DOI | 10.1007/s10384-024-01141-8 |
| Web of Science KeyUT | 001412688900001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10384-024-01141-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mukunoki, Hiroshi| Okoshi, Hirofumi| |
| Keywords | free trade agreements managerial incentives rules of origin transfer pricing |
| Published Date | 2025-01-28 |
| Publication Title | Review of International Economics |
| Publisher | Wiley |
| ISSN | 0965-7576 |
| NCID | AA10959196 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| DOI | 10.1111/roie.12790 |
| Web of Science KeyUT | 001406893100001 |
| Related Url | isVersionOf https://doi.org/10.1111/roie.12790 |
| FullText URL | fulltext20250213-02.pdf suppl20250213-02.pdf |
|---|---|
| Author | Mukohara, Fumiaki| Iwata, Kazuma| Ishino, Takamasa| Inozume, Takashi| Nagasaki, Joji| Ueda, Youki| Suzawa, Ken| Ueno, Toshihide| Ikeda, Hideki| Kawase, Katsushige| Saeki, Yuka| Kawashima, Shusuke| Yamashita, Kazuo| Kawahara, Yu| Nakamura, Yasuhiro| Honobe-Tabuchi, Akiko| Watanabe, Hiroko| Dansako, Hiromichi| Kawamura, Tatsuyoshi| Suzuki, Yutaka| Honda, Hiroaki| Mano, Hiroyuki| Toyooka, Shinichi| Kawazu, Masahito| Togashi, Yosuke| |
| Keywords | cancer immunology somatic mutation T cell tumor-infiltrating lymphocytes |
| Note | This is an Accepted Manuscript of an article published by Proceedings of the National Academy of Sciences.| This fulltext file will be available in Feb. 2025.| |
| Published Date | 2024-08-21 |
| Publication Title | Proceedings of the National Academy of Sciences |
| Volume | volume121 |
| Issue | issue35 |
| Publisher | Proceedings of the National Academy of Sciences |
| Start Page | e2320189121 |
| ISSN | 0027-8424 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 the Author(s). |
| File Version | author |
| PubMed ID | 39167601 |
| DOI | 10.1073/pnas.2320189121 |
| Web of Science KeyUT | 001408603100001 |
| Related Url | isVersionOf https://doi.org/10.1073/pnas.2320189121 |
| Author | Arakawa, Jinta| Yabuki, Ryo| Uemori, Takeshi| Ito, Masato| Yaguchi, Kenichi| |
|---|---|
| Keywords | Small fatigue crack Crystal orientation CP-FEM EBSD |
| Note | © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2027.| |
| Published Date | 2025-03-15 |
| Publication Title | Engineering Failure Analysis |
| Volume | volume170 |
| Publisher | Elsevier BV |
| Start Page | 109242 |
| ISSN | 1350-6307 |
| NCID | AA11028313 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 Elsevier Ltd. |
| File Version | author |
| DOI | 10.1016/j.engfailanal.2024.109242 |
| Web of Science KeyUT | 001405677600001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.engfailanal.2024.109242 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobayashi, Yasuyuki| Sano, Shunji| Narumiya, Yuto| Kimura, Ayari| Suzuki, Etsuji| Kasahara, Shingo| Kotani, Yasuhiro| |
| Keywords | Truncus arteriosus Staged repair Primary repair Pulmonary artery banding Risk stratification |
| Note | The version of record of this article, first published in Pediatric Cardiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00246-025-03790-z| |
| Published Date | 2025-01-30 |
| Publication Title | Pediatric Cardiology |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 0172-0643 |
| NCID | AA00361536 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| PubMed ID | 39883183 |
| DOI | 10.1007/s00246-025-03790-z |
| Web of Science KeyUT | 001409350800001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00246-025-03790-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Naomi| Mitsui, Takashi| Tamai, Kei| Hirota, Tomoya| Masuyama, Hisashi| Yorifuji, Takashi| |
| Keywords | Cesarean delivery Delivery methods Long-term outcome Child development Outcome-wide approach |
| Published Date | 2025-01-20 |
| Publication Title | Scientific Reports |
| Volume | volume15 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 2485 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| PubMed ID | 39833288 |
| DOI | 10.1038/s41598-025-87043-2 |
| Web of Science KeyUT | 001402008500024 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-025-87043-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Morita, Satoru| Otsuka, Yuki| Masuda, Yohei| Soejima, Yoshiaki| Otsuka, Fumio| |
| Keywords | calcium pyrophosphate crystal deposition disease crowned dens syndrome dental treatment fever neck pain |
| Published Date | 2025-02-02 |
| Publication Title | Clinical Case Reports |
| Volume | volume13 |
| Issue | issue2 |
| Publisher | Wiley |
| Start Page | e70168 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 39902195 |
| DOI | 10.1002/ccr3.70168 |
| Web of Science KeyUT | 001410822700001 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.70168 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamada, Yuto| Fujiwara, Masaki| Nakaya, Naoki| Otsuki, Koji| Shimazu, Taichi| Fujimori, Maiko| Hinotsu, Shiro| Nagoshi, Kiwamu| Uchitomi, Yosuke| Inagaki, Masatoshi| |
| Keywords | bipolar disorder cancer screening COVID-19 healthcare disparities schizophrenia |
| Published Date | 2025-02-02 |
| Publication Title | Psychiatry and Clinical Neurosciences Reports |
| Volume | volume4 |
| Issue | issue1 |
| Publisher | Wiley |
| Start Page | e70062 |
| ISSN | 2769-2558 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 39902101 |
| DOI | 10.1002/pcn5.70062 |
| Web of Science KeyUT | 001410823100001 |
| Related Url | isVersionOf https://doi.org/10.1002/pcn5.70062 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kato, Koji| Nakajima, Yoshiki| Xing, Jian| Kumazawa, Minoru| Ogawa, Haruya| Shen, Jian-Ren| Ifuku, Kentaro| Nagao, Ryo| |
| Published Date | 2024-10-31 |
| Publication Title | eLife |
| Volume | volume13 |
| Publisher | eLife Sciences Publications |
| Start Page | RP99858 |
| ISSN | 2050-084X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Kato, Nakajima, Xing et al. |
| File Version | publisher |
| PubMed ID | 39480899 |
| DOI | 10.7554/eLife.99858 |
| Web of Science KeyUT | 001394525300001 |
| Related Url | isVersionOf https://doi.org/10.7554/eLife.99858 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Kazuyuki| Uchida, Daisuke| Takeuchi, Yasuto| Kato, Hironari| Fujii, Yuki| Harada, Kei| Hattori, Nao| Sato, Ryosuke| Obata, Taisuke| Matsumi, Akihiro| Miyamoto, Kazuya| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yasui, Kazuya| Harada, Ryo| Fujii, Masakuni| Otsuka, Motoyuki| |
| Keywords | ablation techniques endosonography neuroendocrine tumors pancreatic neoplasms pilot projects |
| Published Date | 2025-01-29 |
| Publication Title | DEN Open |
| Volume | volume5 |
| Issue | issue1 |
| Publisher | Wiley |
| Start Page | e70073 |
| ISSN | 2692-4609 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 39885893 |
| DOI | 10.1002/deo2.70073 |
| Web of Science KeyUT | 001408662000001 |
| Related Url | isVersionOf https://doi.org/10.1002/deo2.70073 |
| FullText URL | srfa_114_cover_e.pdf |
|---|---|
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| FullText URL | srfa_114_colophon.pdf |
|---|---|
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| Title Alternative | The List of Published by Members of the Faculty From January to December 2024. |
|---|---|
| FullText URL | srfa_114_027_038.pdf |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| Start Page | 27 |
| End Page | 38 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| Title Alternative | Elucidation of plant-bacterial pathogen interactions for the control of bacterial blight on cruciferous crops |
|---|---|
| FullText URL | srfa_114_021_025.pdf |
| Author | Sakata, Nanami| |
| Abstract | Pseudomonas cannabina pv. alisalensis (Pcal), the causative agent of bacterial blight on cruciferous crops, is an economically important pathogen worldwide. We have conducted several studies on the interactions between plants and pathogenic bacteria to develop effective control strategies for this disease. Using forward and reverse genetics, we identified several virulence factors, including the type III secretion system, membrane transporters, transcriptional factors, and amino acid metabolism. Additionally, we emphasized the role of coronatine, a toxin produced by Pcal, which promotes stomatal reopening and suppresses salicylic acid accumulation in plants. We also examined plant defense mechanisms activated by one of the plant defense activators, acibenzolar-S-methyl (ASM). ASM enhanced stomatal-based defense, resulting in reduction of bacterial entry and disease development. Moreover, we explored innovative control strategies for bacterial disease and demonstrated that amino acids and cellulose nanofiber are efficient and environmentally friendly control strategies. These studies advance our understanding of plant-pathogen dynamics and offer promising, sustainable approaches for managing bacterial blight disease in cruciferous crops. |
| Keywords | Plant pathogenic bacteria Pseudomonas Cruciferous Plant protection Stomata |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| Start Page | 21 |
| End Page | 25 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| Title Alternative | Uncovering the role of arcuate kisspeptin neurons as a source of the gonadotropin-releasing hormone pulse generator using gene-modified rats |
|---|---|
| FullText URL | srfa_114_011_020.pdf |
| Author | Nagae, Mayuko| Uenoyama, Yoshihisa| |
| Abstract | Strategies for increasing reproductive performance are needed for domestic animals because for example the conception (pregnancy) rate has decreased in dairy cows around the world. Reproductive function is controlled by hormones released by the hypothalamus-pituitary-gonadal axis in mammals, including domestic animals. Of those hormones, tonic (pulsatile) gonadotropin-releasing hormone (GnRH) release is fundamentally important for gonadotropin release and gonadal activity. Therefore, uncovering the mechanism controlling GnRH pulses, that is GnRH pulse generator, is essential to improve reproductive technologies for domestic animals. The present review is focused on the indispensable role of arcuate nucleus (ARC) kisspeptin neurons (also known as KNDy neurons) as the GnRH pulse generator in mammals. First, we give a brief overview of studies on hypothalamic kisspeptin neurons throughout the past two decades. Second, we review studies that have provided direct evidence that ARC kisspeptin neurons serve as the GnRH pulse generator, with a special focus on our gene-modified rat models. Finally, we discuss the mechanism underlying GnRH pulse generation. The knowledge obtained from gene-modified rat models should be clinically important and could be adapted to new tools to improve reproductive performance in livestock by stimulating GnRH/gonadotropin pulses. |
| Keywords | gene-modified rats GnRH kisspeptin LH pulse generator |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| Start Page | 11 |
| End Page | 20 |
| ISSN | 2186-7755 |
| language | English |
| File Version | publisher |
| FullText URL | srfa_114_001_010.pdf |
|---|---|
| Author | Saitoh, Kuniyuki| Murakami, Tomohiro| Nakamura, Yumi| Nishibori, Misa| Takagoshi, Yuki| Hirai, Yoshihiko| |
| Abstract | Eleven crops were cultivated: maize, sunflower, soybean, groundnuts, sesame, kenaf, barley, wheat, rice, potato, and sweet potato. The crop growth rate (CGR) and specific dark-respiration rate (Rs) were measured, and growth efficiency GE =CGR/(CGR+R) (R, respiratory loss) was calculated. In each crop, whole-plant Rs reached a maximum in the earlier stages of growth, declined rapidly until the early reproductive growth, and remained almost constant during the ripening period. The Rs of leaves was higher than that of stems during the reproductive growth period, except for maize and potato. The Rs of storage organs was highest in the earlier stages, followed by a rapid decline to similar or lower values than those of leaves and stems during the ripening period. The GE in whole plant was higher than 60% in wheat, maize, barley, sunflower, rice, kenaf, sesame, but lower in soybean, sweet potato and groundnuts, and lowest in potato, which was affected by the higher respiratory loss. The GE in whole plant during the reproductive growth period was significantly lower, which we attributed to increased maintenance costs due to the increase of non-assimilative organs, and decrease in the dry weight of vegetative organs. A positive correlation was observed between the carbohydrate content of storage organs and GE, indicating that a crop with higher carbohydrate content in storage organs tended to have a higher GE. Crops with higher protein and crude fat content in storage organs tended to have lower GE. The GE over the growing season was low for kenaf, a fiber crop which contains high molecular weight compounds such as lignin and cellulose, and lower for sesame, groundnuts, and soybean, which contain high oil and protein and have high respiration costs for the synthesis of storage materials, suggesting that these higher respiration costs are related to lower dry matter production and hence lower yields. |
| Keywords | Cereal crops Oil crops Crop growth rate Dark-respiration Growth efficiency Leguminous crops Nutrients composition Respiratory loss Root and tuber crops |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| Start Page | 1 |
| End Page | 10 |
| ISSN | 2186-7755 |
| language | English |
| File Version | publisher |
| FullText URL | srfa_114_contents.pdf |
|---|---|
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| FullText URL | srfa_114_cover.pdf |
|---|---|
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2025-02-01 |
| Volume | volume114 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
