検索結果 - 岡山大学学術成果リポジトリ

Gastrectomy Causes an Imbalance in the Trunk Muscles

JaLCDOI	10.18926/AMO/68354
フルテキストURL	79_1_009.pdf
著者	Ikeya, Nanami\| Okita, Atsushi\| Hashida, Shinsuke\| Yamamoto, Sumiharu\| Ikeda, Hirokuni\| Tsukuda, Kazunori\| Toyooka, Shinichi\|
抄録	Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.
キーワード	sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	9
終了ページ	19
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012155
Web of Science KeyUT	001440463800002

Endothelial Cell Polarity in Health and Disease

JaLCDOI	10.18926/AMO/68353
フルテキストURL	79_1_001.pdf
著者	Thiha, Moe\| Hikita, Takao\| Nakayama, Masanori\|
抄録	Endothelial cell polarity is fundamental to the organization and function of blood vessels, influencing processes such as angiogenesis, vascular stability, and response to shear stress. This review elaborates on the molecular mechanisms that regulate endothelial cell polarity, focusing on key players like the PAR polarity complex and Rho family GTPases. These pathways coordinate the front–rear, apical–basal and planar polarity of endothelial cells, which are essential for the proper formation and maintenance of vascular structures. In health, endothelial polarity ensures not only the orderly development of blood vessels, with tip cells adopting distinct polarities during angiogenesis, but also ensures proper vascular integrity and function. In disease states, however, disruptions in polarity contribute to pathologies such as coronary artery disease, where altered planar polarity exacerbates atherosclerosis, and cancer, where disrupted polarity in tumor vasculature leads to abnormal vessel growth and function. Understanding cell polarity and its disruption is fundamental not only to comprehending how cells interact with their microenvironment and organize themselves into complex, organ-specific tissues but also to developing novel, targeted, and therapeutic strategies for a range of diseases, from cardiovascular disorders to malignancies, ultimately improving patient outcomes.
キーワード	blood vessel endothelial cell cell polarity atherosclerosis cancer
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	1
終了ページ	7
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012154
Web of Science KeyUT	001440463800001

Relationships between tilt angles of rectus muscles and positions of rectus muscle pulleys in patients with sagging eye syndrome

フルテキストURL	fulltext.pdf
著者	Kono, Reika\| Hamasaki, Ichiro\| Kishimoto, Fumiko\| Shibata, Kiyo\| Morisawa, Shin\| Morizane, Yuki\|
キーワード	Orbital pulley Sagging eye syndrome Distance esotropia Cyclovertical strabismus Aging
備考	The version of record of this article, first published in Japanese Journal of Ophthalmology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10384-024-01141-8\|
発行日	2025-02-04
出版物タイトル	Japanese Journal of Ophthalmology
巻	69巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	1
終了ページ	9
ISSN	0021-5155
NCID	AA00691177
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39903417
DOI	10.1007/s10384-024-01141-8
Web of Science KeyUT	001412688900001
関連URL	isVersionOf https://doi.org/10.1007/s10384-024-01141-8

Wake Not a Sleeping Lion: Free Trade Agreements and Decision Rights in Multinationals

フルテキストURL	fulltext.pdf
著者	Mukunoki, Hiroshi\| Okoshi, Hirofumi\|
キーワード	free trade agreements managerial incentives rules of origin transfer pricing
発行日	2025-01-28
出版物タイトル	Review of International Economics
出版者	Wiley
ISSN	0965-7576
NCID	AA10959196
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
DOI	10.1111/roie.12790
Web of Science KeyUT	001406893100001
関連URL	isVersionOf https://doi.org/10.1111/roie.12790

Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity

フルテキストURL	fulltext20250213-02.pdf suppl20250213-02.pdf
著者	Mukohara, Fumiaki\| Iwata, Kazuma\| Ishino, Takamasa\| Inozume, Takashi\| Nagasaki, Joji\| Ueda, Youki\| Suzawa, Ken\| Ueno, Toshihide\| Ikeda, Hideki\| Kawase, Katsushige\| Saeki, Yuka\| Kawashima, Shusuke\| Yamashita, Kazuo\| Kawahara, Yu\| Nakamura, Yasuhiro\| Honobe-Tabuchi, Akiko\| Watanabe, Hiroko\| Dansako, Hiromichi\| Kawamura, Tatsuyoshi\| Suzuki, Yutaka\| Honda, Hiroaki\| Mano, Hiroyuki\| Toyooka, Shinichi\| Kawazu, Masahito\| Togashi, Yosuke\|
キーワード	cancer immunology somatic mutation T cell tumor-infiltrating lymphocytes
備考	This is an Accepted Manuscript of an article published by Proceedings of the National Academy of Sciences.\| This fulltext file will be available in Feb. 2025.\|
発行日	2024-08-21
出版物タイトル	Proceedings of the National Academy of Sciences
巻	121巻
号	35号
出版者	Proceedings of the National Academy of Sciences
開始ページ	e2320189121
ISSN	0027-8424
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 the Author(s).
論文のバージョン	author
PubMed ID	39167601
DOI	10.1073/pnas.2320189121
Web of Science KeyUT	001408603100001
関連URL	isVersionOf https://doi.org/10.1073/pnas.2320189121

Evaluation of small fatigue crack deflection behavior on copper using electron backscatter diffraction and crystal plasticity finite element analysis

著者	Arakawa, Jinta\| Yabuki, Ryo\| Uemori, Takeshi\| Ito, Masato\| Yaguchi, Kenichi\|
キーワード	Small fatigue crack Crystal orientation CP-FEM EBSD
備考	© 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Jan. 2027.\|
発行日	2025-03-15
出版物タイトル	Engineering Failure Analysis
巻	170巻
出版者	Elsevier BV
開始ページ	109242
ISSN	1350-6307
NCID	AA11028313
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Elsevier Ltd.
論文のバージョン	author
DOI	10.1016/j.engfailanal.2024.109242
Web of Science KeyUT	001405677600001
関連URL	isVersionOf https://doi.org/10.1016/j.engfailanal.2024.109242

Management Strategies for Truncus Arteriosus: A Comparative Analysis of Staged vs. Primary Repair

フルテキストURL	fulltext.pdf
著者	Kobayashi, Yasuyuki\| Sano, Shunji\| Narumiya, Yuto\| Kimura, Ayari\| Suzuki, Etsuji\| Kasahara, Shingo\| Kotani, Yasuhiro\|
キーワード	Truncus arteriosus Staged repair Primary repair Pulmonary artery banding Risk stratification
備考	The version of record of this article, first published in Pediatric Cardiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00246-025-03790-z\|
発行日	2025-01-30
出版物タイトル	Pediatric Cardiology
出版者	Springer Science and Business Media LLC
ISSN	0172-0643
NCID	AA00361536
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39883183
DOI	10.1007/s00246-025-03790-z
Web of Science KeyUT	001409350800001
関連URL	isVersionOf https://doi.org/10.1007/s00246-025-03790-z

Cesarean delivery on child health and development in Japanese nationwide birth cohort

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Mitsui, Takashi\| Tamai, Kei\| Hirota, Tomoya\| Masuyama, Hisashi\| Yorifuji, Takashi\|
キーワード	Cesarean delivery Delivery methods Long-term outcome Child development Outcome-wide approach
発行日	2025-01-20
出版物タイトル	Scientific Reports
巻	15巻
号	1号
出版者	Nature Portfolio
開始ページ	2485
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39833288
DOI	10.1038/s41598-025-87043-2
Web of Science KeyUT	001402008500024
関連URL	isVersionOf https://doi.org/10.1038/s41598-025-87043-2

Crowned Dens Syndrome Triggered by Dental Treatment

フルテキストURL	fulltext.pdf
著者	Morita, Satoru\| Otsuka, Yuki\| Masuda, Yohei\| Soejima, Yoshiaki\| Otsuka, Fumio\|
キーワード	calcium pyrophosphate crystal deposition disease crowned dens syndrome dental treatment fever neck pain
発行日	2025-02-02
出版物タイトル	Clinical Case Reports
巻	13巻
号	2号
出版者	Wiley
開始ページ	e70168
ISSN	2050-0904
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	39902195
DOI	10.1002/ccr3.70168
Web of Science KeyUT	001410822700001
関連URL	isVersionOf https://doi.org/10.1002/ccr3.70168

Trends in uptake of cancer screening among people with severe mental illness before and after the COVID-19 pandemic in Japan: A repeated cross-sectional study

フルテキストURL	fulltext.pdf
著者	Yamada, Yuto\| Fujiwara, Masaki\| Nakaya, Naoki\| Otsuki, Koji\| Shimazu, Taichi\| Fujimori, Maiko\| Hinotsu, Shiro\| Nagoshi, Kiwamu\| Uchitomi, Yosuke\| Inagaki, Masatoshi\|
キーワード	bipolar disorder cancer screening COVID-19 healthcare disparities schizophrenia
発行日	2025-02-02
出版物タイトル	Psychiatry and Clinical Neurosciences Reports
巻	4巻
号	1号
出版者	Wiley
開始ページ	e70062
ISSN	2769-2558
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	39902101
DOI	10.1002/pcn5.70062
Web of Science KeyUT	001410823100001
関連URL	isVersionOf https://doi.org/10.1002/pcn5.70062

Structural basis for molecular assembly of fucoxanthin chlorophyll a/c-binding proteins in a diatom photosystem I supercomplex

フルテキストURL	fulltext.pdf
著者	Kato, Koji\| Nakajima, Yoshiki\| Xing, Jian\| Kumazawa, Minoru\| Ogawa, Haruya\| Shen, Jian-Ren\| Ifuku, Kentaro\| Nagao, Ryo\|
発行日	2024-10-31
出版物タイトル	eLife
巻	13巻
出版者	eLife Sciences Publications
開始ページ	RP99858
ISSN	2050-084X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Kato, Nakajima, Xing et al.
論文のバージョン	publisher
PubMed ID	39480899
DOI	10.7554/eLife.99858
Web of Science KeyUT	001394525300001
関連URL	isVersionOf https://doi.org/10.7554/eLife.99858

Efficacy and safety of endoscopic ultrasonography-guided radiofrequency ablation of small pancreatic neuroendocrine neoplasms: A prospective, pilot study

フルテキストURL	fulltext.pdf
著者	Matsumoto, Kazuyuki\| Uchida, Daisuke\| Takeuchi, Yasuto\| Kato, Hironari\| Fujii, Yuki\| Harada, Kei\| Hattori, Nao\| Sato, Ryosuke\| Obata, Taisuke\| Matsumi, Akihiro\| Miyamoto, Kazuya\| Horiguchi, Shigeru\| Tsutsumi, Koichiro\| Yasui, Kazuya\| Harada, Ryo\| Fujii, Masakuni\| Otsuka, Motoyuki\|
キーワード	ablation techniques endosonography neuroendocrine tumors pancreatic neoplasms pilot projects
発行日	2025-01-29
出版物タイトル	DEN Open
巻	5巻
号	1号
出版者	Wiley
開始ページ	e70073
ISSN	2692-4609
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	39885893
DOI	10.1002/deo2.70073
Web of Science KeyUT	001408662000001
関連URL	isVersionOf https://doi.org/10.1002/deo2.70073

裏表紙・英文目次

フルテキストURL	srfa_114_cover_e.pdf
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher

奥付

フルテキストURL	srfa_114_colophon.pdf
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher

公表学術論文等リスト　2024

タイトル（別表記）	The List of Published by Members of the Faculty From January to December 2024.
フルテキストURL	srfa_114_027_038.pdf
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
開始ページ	27
終了ページ	38
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher

アブラナ科植物黒斑細菌病の防除に向けた植物－病原細菌の相互作用の解明

タイトル（別表記）	Elucidation of plant-bacterial pathogen interactions for the control of bacterial blight on cruciferous crops
フルテキストURL	srfa_114_021_025.pdf
著者	坂田七海\|
抄録	Pseudomonas cannabina pv. alisalensis (Pcal), the causative agent of bacterial blight on cruciferous crops, is an economically important pathogen worldwide. We have conducted several studies on the interactions between plants and pathogenic bacteria to develop effective control strategies for this disease. Using forward and reverse genetics, we identified several virulence factors, including the type III secretion system, membrane transporters, transcriptional factors, and amino acid metabolism. Additionally, we emphasized the role of coronatine, a toxin produced by Pcal, which promotes stomatal reopening and suppresses salicylic acid accumulation in plants. We also examined plant defense mechanisms activated by one of the plant defense activators, acibenzolar-S-methyl (ASM). ASM enhanced stomatal-based defense, resulting in reduction of bacterial entry and disease development. Moreover, we explored innovative control strategies for bacterial disease and demonstrated that amino acids and cellulose nanofiber are efficient and environmentally friendly control strategies. These studies advance our understanding of plant-pathogen dynamics and offer promising, sustainable approaches for managing bacterial blight disease in cruciferous crops.
キーワード	Plant pathogenic bacteria Pseudomonas Cruciferous Plant protection Stomata
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
開始ページ	21
終了ページ	25
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher

遺伝子改変ラットを用いた弓状核キスペプチンニューロンの性腺刺激ホルモン放出ホルモンパルスジェネレーターとしての役割解明

タイトル（別表記）	Uncovering the role of arcuate kisspeptin neurons as a source of the gonadotropin-releasing hormone pulse generator using gene-modified rats
フルテキストURL	srfa_114_011_020.pdf
著者	長江麻佑子\| 上野山賀久\|
抄録	Strategies for increasing reproductive performance are needed for domestic animals because for example the conception (pregnancy) rate has decreased in dairy cows around the world. Reproductive function is controlled by hormones released by the hypothalamus-pituitary-gonadal axis in mammals, including domestic animals. Of those hormones, tonic (pulsatile) gonadotropin-releasing hormone (GnRH) release is fundamentally important for gonadotropin release and gonadal activity. Therefore, uncovering the mechanism controlling GnRH pulses, that is GnRH pulse generator, is essential to improve reproductive technologies for domestic animals. The present review is focused on the indispensable role of arcuate nucleus (ARC) kisspeptin neurons (also known as KNDy neurons) as the GnRH pulse generator in mammals. First, we give a brief overview of studies on hypothalamic kisspeptin neurons throughout the past two decades. Second, we review studies that have provided direct evidence that ARC kisspeptin neurons serve as the GnRH pulse generator, with a special focus on our gene-modified rat models. Finally, we discuss the mechanism underlying GnRH pulse generation. The knowledge obtained from gene-modified rat models should be clinically important and could be adapted to new tools to improve reproductive performance in livestock by stimulating GnRH/gonadotropin pulses.
キーワード	gene-modified rats GnRH kisspeptin LH pulse generator
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
開始ページ	11
終了ページ	20
ISSN	2186-7755
言語	英語
論文のバージョン	publisher

Effects of dark respiration on dry matter production of various crop species

フルテキストURL	srfa_114_001_010.pdf
著者	Saitoh, Kuniyuki\| Murakami, Tomohiro\| Nakamura, Yumi\| Nishibori, Misa\| Takagoshi, Yuki\| Hirai, Yoshihiko\|
抄録	Eleven crops were cultivated: maize, sunflower, soybean, groundnuts, sesame, kenaf, barley, wheat, rice, potato, and sweet potato. The crop growth rate (CGR) and specific dark-respiration rate (Rs) were measured, and growth efficiency GE =CGR/(CGR+R) (R, respiratory loss) was calculated. In each crop, whole-plant Rs reached a maximum in the earlier stages of growth, declined rapidly until the early reproductive growth, and remained almost constant during the ripening period. The Rs of leaves was higher than that of stems during the reproductive growth period, except for maize and potato. The Rs of storage organs was highest in the earlier stages, followed by a rapid decline to similar or lower values than those of leaves and stems during the ripening period. The GE in whole plant was higher than 60% in wheat, maize, barley, sunflower, rice, kenaf, sesame, but lower in soybean, sweet potato and groundnuts, and lowest in potato, which was affected by the higher respiratory loss. The GE in whole plant during the reproductive growth period was significantly lower, which we attributed to increased maintenance costs due to the increase of non-assimilative organs, and decrease in the dry weight of vegetative organs. A positive correlation was observed between the carbohydrate content of storage organs and GE, indicating that a crop with higher carbohydrate content in storage organs tended to have a higher GE. Crops with higher protein and crude fat content in storage organs tended to have lower GE. The GE over the growing season was low for kenaf, a fiber crop which contains high molecular weight compounds such as lignin and cellulose, and lower for sesame, groundnuts, and soybean, which contain high oil and protein and have high respiration costs for the synthesis of storage materials, suggesting that these higher respiration costs are related to lower dry matter production and hence lower yields.
キーワード	Cereal crops Oil crops Crop growth rate Dark-respiration Growth efficiency Leguminous crops Nutrients composition Respiratory loss Root and tuber crops
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
開始ページ	1
終了ページ	10
ISSN	2186-7755
言語	英語
論文のバージョン	publisher

フルテキストURL	srfa_114_contents.pdf
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher

表紙

フルテキストURL	srfa_114_cover.pdf
出版物タイトル	岡山大学農学部学術報告
発行日	2025-02-01
巻	114巻
ISSN	2186-7755
言語	日本語
論文のバージョン	publisher