| ID | 31247 |
| JaLCDOI | |
| FullText URL | |
| Author |
Kaneyuki, Takao
Shohmori, Toshikiyo
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| Abstract | Diencephalon testosterone 5 alpha-reductase activity and plasma testosterone level were measured in the rat with liver injury caused by i.p. administration of CCl4. Testosterone levels in plasma were decreased after CCl4 injection in both group I (0.1ml/150g B.W./once a day for 2 days) and group II (0.01ml/150g B.W./twice a week for three weeks). 5 alpha-Reductase activity in the diencephalon was decreased both on the 7th day after administration in group I and in group II, while being transiently increased on the 1st day after administration in group I. These results suggest that testosterone metabolism in the brain is inhibited during liver disorders.
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| Keywords | liver injury
CCI<sub>4</sub>
testosterone 5α-reductase
testosterone
estradiol-17β
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| Amo Type | Brief Note
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| Publication Title |
Acta Medica Okayama
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| Published Date | 1981-10
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| Volume | volume35
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| Issue | issue4
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| Publisher | Okayama University Medical School
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| Start Page | 279
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| End Page | 284
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| File Version | publisher
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| Refereed |
True
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| PubMed ID | |
| Web of Science KeyUT |
