ID | 31247 |
JaLCDOI | |
フルテキストURL | |
著者 |
Kaneyuki, Takao
Okayama Prefectural Junior College
Shohmori, Toshikiyo
Okayama University
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抄録 | Diencephalon testosterone 5 alpha-reductase activity and plasma testosterone level were measured in the rat with liver injury caused by i.p. administration of CCl4. Testosterone levels in plasma were decreased after CCl4 injection in both group I (0.1ml/150g B.W./once a day for 2 days) and group II (0.01ml/150g B.W./twice a week for three weeks). 5 alpha-Reductase activity in the diencephalon was decreased both on the 7th day after administration in group I and in group II, while being transiently increased on the 1st day after administration in group I. These results suggest that testosterone metabolism in the brain is inhibited during liver disorders.
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キーワード | liver injury
CCI<sub>4</sub>
testosterone 5α-reductase
testosterone
estradiol-17β
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Amo Type | Brief Note
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出版物タイトル |
Acta Medica Okayama
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発行日 | 1981-10
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巻 | 35巻
|
号 | 4号
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出版者 | Okayama University Medical School
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開始ページ | 279
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終了ページ | 284
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT |