JaLCDOI 10.18926/40209
Title Alternative Some Clinical Observations on the Menopausal Syndrome and its Therapeutic Approach
FullText URL pitsr_030_046_054.pdf
Author Kumamoto, Hirotada|
Abstract In order to observe the effectiveness of the androgen+estrogen therapy used singly or in combination with the meprobamate therapy, the author has determined the menopausal index, the total serum cholesterol and the systolic blood pressure before and after the administration of these treatments. The following results have been obtained. 1) The menopausal index (Kupperman, 1953) declines more markedly fol1owing the application of the combined therapies than after the use of either, administered singly. 2) Total serum cholesterol decreases most pronouncedly following the use of the combined therapies, to a lesser degree following the administration of A+E, still less following a single administration of meprobamate. It has been found, moreover, that although A+E therapy appreciably decreases total serum cholesterol, the effectiveness of meprobamate is slight in this respect. 3) Either therapy tends to stabilize blood pressure, but the combined treatment is more effective in this regard. It may safely be concluded that the use of these therapies singly or combined, will provide one of the most effective therapeutic approaches to the menopausal syndrome, the more especially so because of the absence of side effects, an important consideration when long term treatment, required in most such cases, is contemplated.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 46
End Page 54
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002401090
JaLCDOI 10.18926/21216
Title Alternative Genetic relationship between the Hiroshima and Ryoke granites as indicated by some geochemical evidence
FullText URL pitsr_045_033_046.pdf
Author Honma, Hiroji|
Publication Title 岡山大学温泉研究所報告
Published Date 1976-03-25
Volume volume45
Start Page 33
End Page 46
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310988
JaLCDOI 10.18926/21158
Title Alternative Experimental study of sulfur isotope exchange between S0(4)(2-) and H(2)S (aqueous) at 400℃ and 1000 bars water pressure
FullText URL pitsr_050_001_015.pdf
Author Kamada, Emi| Sakai, Hitoshi| Kishima, Noriaki|
Abstract Experimental procedures used in this study are the same as those developed by Sakai and Dickson (1978). 0.005 M Na(2)S(2)O(3) solutions were heated to 400℃ under 1000 bar water pressure in a gold bag of Dickson gold-bag equipment (Fig. 1). At an elevated temperature Na(2)S(2)O(3) quickly and completely decomposed into 1:1 mixture of SO(4)(2-) and H(2)S (eq. (1)) and subsequent isotope exchange (eq. (2)) was monitored by consecutively withdrawing aliquots of solution for chemical and isotopic analyses at desired time intervals. For the preparation of SO(2) for isotope analyses, 2 to 5 mg BaSO(4) was thoroughly mixed with silica glass powder of 10 times the BaSO(4) in weight and heated to 1400℃ or so in sealed, evacuated silica glass tubings (see Fig. 2 and equation (4)). The technique is a modification of Holt and Engelkemeir (1971). The (18)O/(16)O ratios of SO(2) thus formed stayed constant by exchange with silica glass powder (Fig. 3). Numerical data of the three runs performed in this study are summarized in Tables 1 to 3. In runs 2 and 3, a small aliquot of (34)S- enriched H(2)SO(4) was added into the starting solution and thus equilibrium was approached from above the quilibrium value (see Fig. 4). When isotope exchange occurs between two molecules, X and Y, the reaction rate, r, is related to the extent of exchange, F, at given time, t, by equation (17), where X and Y indicate concentrations of given species, α(e), α(o) and α denote the fractionation factor at equilibrium, at time t=0 and at an arbitrary time t, and F = (α - α(o))/(α(e) - α(0)) or the extent of isotope exchange. Assuming the exchange rate is of the first order with respect to both X and Y and to the β'th power of hydrogen ion activity, a(H)(+), eq. (17) reduces to eq. (19), where k(1) denotes the rate constant. If X, Y and pH of solution stayed constant during the run, the half-time, t(1/2), of the exchange reaction can be obtained graphically as shown in Fig. 5. The t(1/2) for runs 1, 2, and 3 are determined to be 5.8, 5.5 and 6.1 hrs, respectively. Introducing F=0.5 and t=t(1/2) into eq. (19), we obtain eq. (20) which is graphically shown in Fig. 6 using the data by the present work and those by Sakai and Dickson(1978). The numerical values of log k(1) + 0.16 may be obtained by extrapolating the lines to pH=0 and, from these values, the rate constant, k(1) , may be calculated for temperatures of 300° and 400℃. From these two values of k(1) and from the Arrhenius plot, the activation energy of the exchange reaction was calculated to be 22 kcal/mole, a much smaller value than 55 kcal/mole obtained by Igumnov (1977). The value of β is found to be 0.29 at 300℃ and 0.075 at 400℃, although the physico-chemical nature of β is not clear to the present authors. Using these values, eq. (24), where C is a constant, is derived which would enable us to calculate the t(1/2) of any system of known ΣS and pH. However, as we do not know yet how β varies with different systems, eq. (24) is applicable only to limited systems in which temperature, total sulfur contents and pH are similar to those of the present study. Fig. 7 illustrates how t(1/2) varies with pH and total sulfur content at 300° and 400℃ and predicts t(1/2) for some solutions obtainable by hydrothermal reactions of seawater with various igneous rocks. The average equilibrium fractionation factor at 400℃ obtained by this study is 1.0153, in good accord with 1.0151 given by Igumnov et al. (1977). Theoretical fractionation factors between SO(4)(2-) and H(2)S have been calculated by Sakai (1968) , who gives too high values compared to the experimental data obtained by this and other researchers (Fig. 9). In the present study, the reduced partition function ratio (R.P.F.R.) of SO(4)(2-) was recalculated using two sets of the vibrational frequencies of SO(4)(2-) (shown in Table 5) and the valence force fields of Heath and Linnett (1947), which reproduces the observed frequencies of SO(4)(2-) better than Urey-Bradley force field used by Sakai (1968). The results of new calculation are shown in Table 6. This table also includes the R.P.F.R. of H(2)S which was calculated by Thode et al. (1971). Using these new R.P.F.R. of SO(4)(2-) and H(2)S, the fractionation factors between SO(4)(2-) and H(2)S were calculated and are listed in the last column of Table 6 and plotted in Fig. 9. Fig. 9 indicates that the new calculation gives values more shifted from the experimental values than before. The major sulfate ions in our solution at 300° and 400℃ exist as NaSO(4)(-) (Sakai and Dickson, 1978; see also Table 4 of this paper) and, therefore, the measured fractionation factors are those between NaSO(4)(-) and H(2)S. The discrepancy between the theory and experiments may, at least, be partially explained by this fact, although other more important reasons, which are not known to us at the moment, may also exist.
Publication Title 岡山大学温泉研究所報告
Published Date 1980-03-25
Volume volume50
Start Page 1
End Page 15
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310990
JaLCDOI 10.18926/40161
Title Alternative Studies on the uptake of (75)Se-selenomethionine by the pancreas Attempt to augment by the effects of protocols
FullText URL pitsr_040_019_031.pdf
Author Tokunou, Tsuneo|
Abstract Since the introduction of the pancreatic scanning using (75)Se-selenomethionine, there has been various protocols proposed to increase the pancreatic uptake of this isotope. In this experiment several protocols; as diets high carbohydrate meal, high protein meal, high fat meal, and as medicaments pancreozymin, secretin and phydroxyphenylsalicylamide (PHPS), were tested for determining the effects on the uptake of (75)Se-selenomethionine by the pancreas and the liver of the dog. The animals given protocols were sacrified at each of a number of selected times to compare P/L ratio on a percentper-gram concentration of (75)Se-selenomethionine and the total organ concentration of (75)Se-selenomethionine in the pancreas and in the liver. A controlled group of animals were fasted for 24-hour and sacrificed at each of same times. On P/L ratio basis it was found that animals with high carbohydrate meal had better ratio than those with no preparation during first 4-hour post administration. However, animals with each of high protein meal. fat meal and PI-IPS had lower ratio than those with no preparation. On the blood concentration, animals with each of high carbohydrate meal and secretin had lower variation of blood concentration than controlled group. Thus, from the results mentioned above, the protocol by high carbohydrate meal is proved to be useful in pancreatic scanning.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 19
End Page 31
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398153
JaLCDOI 10.18926/40255
Title Alternative A Case of Agammaglobulinemia
FullText URL 024_087_095.pdf
Author Matsumoto, Kinshi| Wakutani, Tohaku|
Abstract A case of agammaglobulinemia, probably of the secondary type, is reported in adult female (45-year-old) with tumor of the mediastinum. The authors described the bibliographical consideration and arose the attention of agammaglobulinemia. Reports on agammaglobulinemia may increase in practise if electrophoresis of the serum protein-fraction is used as a routine examination method.
Publication Title 岡山大学温泉研究所報告
Published Date 1959-01
Volume volume24
Start Page 87
End Page 95
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532364
JaLCDOI 10.18926/40148
Title Alternative The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique
FullText URL pitsr_041_001_002.pdf
Author Matsubaya, Osamu|
Abstract The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique was studied. In this study, a new type of reaction vessel was used (Fig. 1). The reaction time for equilibration using this new reaction vessel was nearly equal to that in the previous study (Fig. 2). The oxygen isotopic ratios of each two samples of pH 2, 4, 7, 8, 9, and 10 were measured. There is no significant difference between the observed δ(18)O values of these samples (Table 1). Therefore it is concluded that the effect of pH of water needs not to be taken into account on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 1
End Page 2
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398148
JaLCDOI 10.18926/40211
FullText URL pitsr_030_066_071.pdf
Author Kitayama, Minoru| Kuwada, Akira| Kawata, Yoshiro|
Abstract The authors gathered 78 cases of gouty arthritis reported in Japan between 1898 and 1960, and analysed them statistically. 1. The incidence of gouty arthritis appears to have increased since about the end of the 2nd World War, especially since 1955. 2. The age of the presumptive onset of the disease is lower in Japanese than in white populations. 3. In many cases, the gouty patients were wrongly diagnosed as rheumatoid arthritis, synovitis or panaritium patients, and only 20 per cent of the cases examined were diagnosed correctly at the first consultation. The author stresses that diagnosis at an early stage is necessary to avoid serious complications such as cardiovascular and renal involvements. If the condition is satisfactorily controlled by diets and drugs, however, the prognosis for gouty patients is excellent.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 66
End Page 71
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002401091
JaLCDOI 10.18926/40271
FullText URL pitsr_020_042_047.pdf
Author Tanaka, Shigeo|
Abstract Differential thermal investigation was made of amorphous hydrous ferric oxides, precipitated on neutralization of ferric chloride solution under different laboratory conditions, ranging from DOC to 85°C in temperature, and from 3 to 12 in pH. Each of the differential thermal curves obtained shows an endothermic peak due to the release of adsorbed water, followed by a exothermic peak due to crystallization of anhydrous ferric oxide to hematite. The temperature corresponding to the exothermic peak varies in the range from 240°C to 460°C accrding to the temperatures and pH values of the solution from which the hydrous ferric oxide is precipitated.
Publication Title 岡山大学温泉研究所報告
Published Date 1958-01
Volume volume20
Start Page 42
End Page 47
ISSN 0369-7142
language English
File Version publisher
NAID 120002462894
JaLCDOI 10.18926/21224
Title Alternative Semi-automatic processing of EPMA data
FullText URL pitsr_044_007_020.pdf
Author Kawasaki, Toshisuke|
Publication Title 岡山大学温泉研究所報告
Published Date 1975-03-25
Volume volume44
Start Page 7
End Page 20
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310998
JaLCDOI 10.18926/40077
Title Alternative A FORTRAN data processing system for the epidemiological data on rheumatic diseases - Part 1. Basic programs for deposit and retrieval of data
FullText URL 046_045_059.pdf
Author Itoh, Keiko| Kitayama, Minoru| Morinaga, Hiroshi| Matsui, Yoshito|
Abstract A set of FORTRAN programs for small computer is described for deposit and retrieval of the epidemiological data, which have been compiled at the Kami-hojo-cho district in Feb. 1972and Feb. 1975. A data file is constructed on a magnetic disk. The following items are recorded and registered on the disk for every person: identification number, full name in Japanese alphabet, sex, date of birth, weight, height, blood pressures, chemical characterics of blood serum and urine, and various complaints of clinical significance (fever, morning stiffness, arthralgia, joint swelling, myalgia, cutaneous rash, aphthous stomatitis, dry eyes, dry mouth, joint deformity, subcutaneous nodules, lymph and parotid gland enlargement, struma, heart murmur, and neulogical findings). All information per one person requires only two IBM cards due to compact encoding of original records. The encode-decode procedures are explained also in the text.
Publication Title 岡山大学温泉研究所報告
Published Date 1977-03-25
Volume volume46
Start Page 45
End Page 59
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40000321122
Author Seki, Masaji|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Oshima, Yoshio|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
JaLCDOI 10.18926/21139
Title Alternative Isotopic Analysis of Rb and Sr Using a Full Automatic Thermal Ionization Mass Spectrometer
FullText URL pitsr_052_051_070.pdf
Author Kagami, Hiroo| Okano, Osamu| Sudo, Hiroshi| Honma, Hiroji|
Abstract Analytical method for strontium isotope ratios and rubidium and strontium concentrations has been established using a full automatic thermal ionization mass spectrometer. The machine is a modified model "MAT 260" of Varian MAT LTD. Each of simultaneously loaded thirteen samples is successively analysed full automatically following to a specific controling program which has been selected as being most suitable for each sample. However, the most characteristic feature of this machine compared to other types is computer controled peak jumping and peak centering before measurment of the signal of each peak. By this the accuracy of isotopic measurement has been surprisingly improved. Analytical procedures are described in detail which include decomposition of samples, separation of Rb and Sr, loading samples on filament and mass spectrometry. Accuracy and reproducibility of isotope analyses are excellent : 43 separate analyses of standard sample NBS 987 over one year gave a mean (87)Sr/(86)Sr ratio of 0.710238 (normalized to the (88)Sr/(86)Sr ratio of 8.375209) with a value of 20δ of 0.000008. The ratio obtained is slightly higher than the value of 0.71014 given by NBS, but it is almost identical to the mean of recently reported twenty analyses. Our determinations for Rb and Sr concentrations of standard samples are as follows : JG-1, Rb 184.4 ppm, Sr 185.5 ppm; JB-l, Rb 41.5Ppm, Sr 448.4 ppm , each of which is near the mean of reported values for corresponding element of the sample (ANDO et al., 1974). Concentrations of Rb and Sr in pure water and regents used in chemical treatement of samples were also measured; a possible error due to the contamination is negligible for most geochemical samples.
Publication Title 岡山大学温泉研究所報告
Published Date 1982-03-25
Volume volume52
Start Page 51
End Page 70
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310968
JaLCDOI 10.18926/40153
Title Alternative Absorption of Medium-chain triglyceride (MCT) in isolated intestinal loops of dog and its effect upon the lipids of serum aud adipose tissue
FullText URL pitsr_041_049_056.pdf
Author Kotakemori, Michiaki|
Abstract The absorption of medium chain triglyceride (MCT) has been investigated with intestinal loop of dog without both bile and pancreatic juce. On optimal state, the average coefficient of fat absorption was 78.1±7.4%. The use of medium chain triglyceride diet for 4 weeks in dogs had some effecton lipids of serum and adipose tissue but minimal change on clinical evidence was found. There was a prompt reduction in the proportion of arachidonic acid and a sustained increase in the proportion of oleic acid and linoleic acid in serum lipid. Analysis on lipids of adipose tissue showed prompt reduction in the proportion of oleic acid and linoleic acid. Neither clinical evidence nor side effect induced with medium chain triglyceride was found.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 49
End Page 56
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398150
Author Honma, Hiroji| Sakai, Hitoshi|
Published Date 1976-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume45
Content Type Data or Dataset
JaLCDOI 10.18926/40341
FullText URL pitsr_013_001_005.pdf
Author Umemoto, Shunji|
Abstract Various colormetric methods for determining magnesium in natural waters have been studied, and the methods using 8-oxyquinolin, ammonium molybdate and titan yellow were studied most frequently(1)), following the studies on the interfering ions(2)). Brilliant yellow(3)), l-amino-2-naphthol-6-sulfonic acid(4)) and other new reagents were also used. E. D. T. A. was used, but the determination by using this reagent is not exact. Present reagent already reported by T. Ashizawa(5)), magneson II, is insoluble in water, soluble in alkali and hardly soluble in ethanol. In the existence of magnesium ion, the color of solution varies from pink-violet (in alkali) and orange (in ethanol) to blue-violet. This variation of color was evaluated photometrically by Shimadzu photoelectric spectrophotometer, and moreover the grades of interference by interfering ions were clarified.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 1
End Page 5
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language English
File Version publisher
NAID 120002484877
JaLCDOI 10.18926/21105
Title Alternative A case report of a family with Peutz-Jeghers syndrome
FullText URL pitsr_054_025_033.pdf
Author Irie, Seiji| Harada, Hideo| Kawabata, Kenji| Shibata, Tsuneo|
Abstract A 58-year-old female was admitted because of colicky abdominal pain. Physical examination revealed firm abdominal wall, increased bowel sounds and multiple pigmented macules on the lips, oral mucosa, soles and volar aspects of the fingers and toes. Hyperventilation and tetanic rigidity of the extremities were also noted. The symptoms were successfully treated by intravenous injection of butropium bromide and diazepam. Roentgenological and fiberscopic examination revealed multiple polyps in the stomach, small intestine and colon ; the small intestine was most heavily loaded with polyps. Biopsy specimen revealed only inflammatory changes. The patient had undergone a resectien of the terminal ileum with polyps 15 years previously because of ileo-ileal intussusception. Histological re-evaluation of the polyp showed an actively proliferating papillary adenoma. The characteristic history and gastrointestinal findings lead us to the examination of the family, which revealed that her father, son and grandson had similar pigmentation of the skin and polyps in the gastrointestinal tract. These characteristic findings and family history permitted us to make a diagnosis of Peutz-Jeghers syndrome. The diagnosis had been missed supposedly because of unawareness of the skin lesions and the lack of hamartoma-like findings in the polyp. The tetanic rigidity of the extremities was probably hyperventilation syndrome induced by severe abdominal pain. The patient has been followed up for possible recurrence of symptoms and a potential malignant change.
Publication Title 岡山大学温泉研究所報告
Published Date 1984-03-25
Volume volume54
Start Page 25
End Page 33
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310995
JaLCDOI 10.18926/19586
FullText URL 007_006_007.pdf
Author Umemoto Shunji|
Publication Title 岡山大学温泉研究所報告
Published Date 1952-08
Volume volume7
Start Page 6
End Page 7
ISSN 0369-7142
language English
File Version publisher
NAID 120002309104
JaLCDOI 10.18926/21214
Title Alternative 斜長石から生成したギブサイトの走査電顕観察―大山および三瓶山降下地積物中の粘土鉱物,その8―
FullText URL pitsr_045_011_024.pdf
Author Tazaki, Kazue|
Abstract 大山降下堆積物中の斜長石のギブサイト化過程を,偏光顕微鏡,X線,示差熱分析,走査型電顕,EPMAを用いて調べた. 斜長石は風化によって,カオリナイト,イライト,ハロイサイト,ギブサイト等を生成することが知られているが,今回,ギブサイト化した斜長石についてのみ検討をおこなった. EPMA分析によれば,一個の斜長石の表面に,Al, Si, Na, Caの多く存在する新鮮な斜長石の部分と,Na, Caをほとんど含まず,多量のAlと,ごく少量のSiを含んでいるギブサイトの部分とが分布し,その境界は, 明瞭であることがわかった(図版2).それぞれの部分の分析値は第1表のとおりである. 走査型電顕による斜長石の微細形態観察から,下記のことが明らかになった. ①新鮮な斜長石の表面は,平滑かまたは離溶ラメラがみとめられる(図版3-1). ②風化過程の初期に,水を合んだ非晶質の薄層が,斜長石の表層に生成する.この非晶質薄層の生成にさき立って,斜長石の表面の一部に, ロート状のくぼみが形成される場合がある(図版3-2,3). ③この非晶質薄層に亀裂が生じる(図版4).一方, ロート状のくぼみの上にも非晶質の薄層ができ,亀裂が生じる(図版8-1,2). ④さらに風化が進むと,ラメラ, 亀裂およびロート状のくぼみを部分的に残しながら,-・部には,ギブサイトの結晶が生成する(図版5). ⑤ギブサイトの結晶は,横1~3μm, 縦2~15μm, 厚さ0.5μm前後の平板状の形態,または,直径15-25μm,厚さ0.5~1μm の円盤上の形態をもつ(図版6). ⑥ギブサイトの結晶は,平板状のものが数段重なり,集合体をなす場合もあり(図版7-1),これは,ブラジルのミナス鉱山産のギブサイトの集合状態(図版7-2)とよく似ている. すなわち,斜長石の表面に,風化により,水を含んだ非晶質の薄層ができ,次に,その薄層に亀裂が生じ,イモゴライトの生成をともないながら,直接ギブサイトが結晶すると考えられる. 地名 Okachi 大河内 Hongu 本宮 Kurayoshi 倉吉 Daisen-Cho 大山町 Shuki 秋喜 Hiruzenbara 蒜山原
Publication Title 岡山大学温泉研究所報告
Published Date 1976-03-25
Volume volume45
Start Page 11
End Page 24
ISSN 0369-7142
language English
File Version publisher
NAID 120002311010
JaLCDOI 10.18926/21325
FullText URL pitsr_034_063_094.pdf
Author Okuno, Takaharu|
Abstract The Kamioka mine, Gifu prefecture, working the largest lead and zinc deposit in Japan, lies in the eastern corner of the Hida gneiss complex. The skarn minerals in this mining district are genetically divided into the following three groups. Skarn A : Recrystallized skarn, formed by a regional metamorphism of impure limestone beds. The creation of skarn A is same in age to the formation of the Hida metamorphic complex. Skarn B : Zoned skarn along the contact between limestone and Inishi syenitic rock, having a same origination to Shimonomoto granite. The formation of skarn B is closely related to the intrusion of Shimonomoto granite. Skarn C : Pyrometasomatic skarn, formed by pyrometasomatic replacement of limestone probably after the deposition of the Mesozoic Tetori formation. The ore deposits of the Kamioka mine are composed of the pyrometasomatic skarn (skarn C) called "Mokuji" and the hydrothermal deposits called "Shiroji". Skarn A and skarn B have no genetical relation to the ore deposits. But skarn A acts the valuable role for the stratigrahical classification of ore deposits and limestone beds.
Publication Title 岡山大学温泉研究所報告
Published Date 1964-10-25
Volume volume34
Start Page 63
End Page 94
ISSN 0369-7142
language English
File Version publisher
NAID 120002310950