JaLCDOI 10.18926/14962
Title Alternative ステロイド依存性重症難治性気管支喘息症例における胃粘膜病変の検討
FullText URL 069_063_067.pdf
Author Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Harada, Seishi| Okamoto, Makoto| Yumoto, Eiichirou| Takata, Shingo| Tanizaki, Yoshiro|
Abstract Recently, we experienced two asthmatic patients with advanced gastric cancer. The two patients had steroid-dependent intractable asthma (SDIA) who had been on administration of corticosteroids for more than 2 years. To determine the influence of pathophysiology of SDIA on stomach mucous lesion, gastroscopic examinations and immunological examinations were performed in eight patients with SDIA, compared with 25 patient with non-SDIA. In patients with SDIA, gastric cancer, its precursor condition and immunosuppressive state were observed. These results suggest that the immunosuppressive state in SDIA induced by the long-term administration of corticosteroids may lead to the risk of gastric cancer development.
Keywords ステロイド依存性重症難治性 (steroid-dependent intractable asthma (SDIA)) 胃癌 (gastric cancer) 免疫抑制 (immunosuppression) リンパ球 (lymphocytes) IgG
Publication Title 岡大三朝分院研究報告
Published Date 1998-12
Volume volume69
Start Page 63
End Page 67
ISSN 0918-7839
language English
File Version publisher
NAID 120002308665
JaLCDOI 10.18926/14963
Title Alternative サーモグラフィーによる体表面温度の測定 2.温水負荷の効果
FullText URL 069_068_075.pdf
Author Hosaki, Yasuhiro| Takata, Shingo| Mitsunobu, Fumihiro| Mifune, Takashi| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Harada, Seishi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| Tsuji, Takao|
Abstract The body surface temperature of 41 patients suffering coldness, numbness or pain in their feet was examined using thermography. Thermographic results were analyzed quantitatively by calculating a recovery ratio as: Recovery ratio =[Total counts of thermography (Pixels) over temperature (T) after cold loading] ÷ [Initial counts over T before cold loading] x 100(%). Three different baseline temperatures, 26℃. 27℃ and 28℃, were used in processing the thermographic results into pictures. The recovery ratio was susceptible to temperature, and we recommend a baseline temperature limitation of 27℃ for clinical study. A bi-modal distribution of recovery ratio was observed in 18 patients with diabetes mellitus. One group (6 subjects) had high recovery ratio between 80%-100%, and another group (10 subjects) had a low recovery ratio between 0%-19%. The results of thermography were also influenced by weather. To reduce the effect of outside temperature, we used pre-loading with hot water at 36℃ for 5 min (hot loading). A large difference in recovery ratio between presence and absence of hot loading was observed in 6 of the 30 subjects. The difference was over-estimated in more than 20% of recovery ratio without hot loading as compared with hot loading in these 6 subjects. The effect of drugs on peripheral circulation, such as beraprost sodium and sarpogrelate hydrochloride, was clear and quantified using thermography under these conditions of hot loading.
Keywords サーモグラフィー (thermography) 糖尿病 (diabetes mellitus) 末梢循環 (peripheral circulation) 冷水負荷 (cold loading) 温水負荷 (hot loading)
Publication Title 岡大三朝分院研究報告
Published Date 1998-12
Volume volume69
Start Page 68
End Page 75
ISSN 0918-7839
language English
File Version publisher
NAID 120002308316
JaLCDOI 10.18926/14964
Title Alternative The effects of perilla seed oil ointment for atopic dermatitis
FullText URL 069_076_081.pdf
Author Miyamoto, Miyuki| Akiyama, Chiaki| Noumi, Michiyo| Takata, Junko| Nisimura, Nobuko| Nakamura, Sumie| Kawakami, Yasuhiro| Okamoto, Makoto| Ashida, Kozo| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Abstract 近年アトピー性皮膚炎が増加しており,工ゴマ油を使った食事療法がアレルギー抑制に有用であることが報告されている。そこで今回,エゴマ油を外用剤として使用するため,亜鉛華単軟膏を基剤とした工コマ軟膏を作製し,アトピー性皮膚炎患者3例を対象にその臨床応用を試みた。その結果,掻痒感の軽減に効果がみられ,また皮膚症状では,丘疹.表皮剥離,苔癬化,落屑などの所見が改善される傾向が見られた。
Keywords アトピー性皮膚炎 エゴマ軟膏 掻痒感
Publication Title 岡大三朝分院研究報告
Published Date 1998-12
Volume volume69
Start Page 76
End Page 81
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308418
JaLCDOI 10.18926/14965
Title Alternative 膵癌における癌遺伝子および癌抑制遺伝子
FullText URL 069_082_087.pdf
Author Ochi, Koji| Matsumura, Naoki| Ichimura, Mitsuko| Mizushima, Takaaki| Harada, Hideo| Hasuoka, Hideaki| Yokoyama, Motohiro| Tsurumi, Tetsuya| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Abstract Recent advances in molecular biology have revealed that a number of oncogenes (K-ras, erbB-2, and Met) and tumor suppressor genes (p53, p16, APC, and DCC) contribute to the development of pancreatic cancer. This paper reviewed the present knowledge of oncogenes and tumor suppressor genes relevant to pancreatic cancer. Further studies on molecular alterations in pancreatic cancer may lead to a better understanding of tumor biology, offering a possibility of development of new diagnostic and therapeutic approaches in the future.
Keywords Pancreatic cancer oncogene tumor suppressor gene genetic mutation
Publication Title 岡大三朝分院研究報告
Published Date 1998-12
Volume volume69
Start Page 82
End Page 87
ISSN 0918-7839
language English
File Version publisher
NAID 120002308547
JaLCDOI 10.18926/14968
FullText URL 069_088_092.pdf
Author 土海 智穂| Terasaki, Kayo| 岡本 和代| 山田 修子|
Abstract 関節の変形と骨破壊を伴い,排泄動作に支障をきたしている慢性関節リウマチ患者に対し改良パンツの作成を試みた。残存機能に合わせはきなれたパンツを=夫することにより,排泄動作が自立でき満足感が得られた。
Keywords 慢性関節リウマチ 改良衣類 排泄自立 満足感
Publication Title 岡大三朝分院研究報告
Published Date 1998-12
Volume volume69
Start Page 88
End Page 92
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308379
Author 岡山大学医学部附属病院三朝分院看護部|
Published Date 1998-12
Publication Title 岡大三朝分院研究報告
Volume volume69
Content Type Others
Author Matsubara, Fumie| Inoue, Taeko| Mitsunobu, Yasuko| Mifune, Takashi| Tanizaki, Yoshiro|
Published Date 1998-12
Publication Title 岡大三朝分院研究報告
Volume volume69
Content Type Data or Dataset
Author 岡山大学医学部附属病院三朝分院|
Published Date 1998-12
Publication Title 岡大三朝分院研究報告
Volume volume69
Content Type Others
JaLCDOI 10.18926/14972
Title Alternative 気管支喘息におけるアレルギー性鼻炎と花粉抗原に対するIgE抗体
FullText URL 068_022_027.pdf
Author Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo|
Abstract IgE antibodies against inhalant allergens were estimated in 53 patients with bronchial asthma in relation to allergic rhinitis. Of them, 20 patients (37.7%) had allergic rhinitis. 1. Asthma + allergic rhinitis were often observed in patients between the ages of 0 and 39. In contrast, asthma alone in those over age 60. 2. A RAST score was positive in house dust mite (HDm)(50.9%), cockroach(24.5%), and Candida (26.4%) in these patients, and the positive rate was not different between patients with and without allergic rhinitis. 3. The frequency of positive RAST against Japanese cedar and rice plants was higher in patients with allergic rhinitis (42.9% and 18.5%) than in those without allergic rhinitis (28.6 and 3.7%), however, the each positive rate or RAST against the two allergens was not significantly different between those with AR and without AR. 4. The number of patients with AR induced by pollen alone (pollinosis) was not large ( 5/53, 9.4%) in the patients with asthma. It was clarified from the results that allergic rhinitis was often observed in asthma patients, but not pollinosis. and that IgE antibodies against Japanese cedar and rice plants were found even in patients without AR.
Keywords bronchial asthma allergic rhinitis IgE antibodies house dust mite Japanese cedar
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 22
End Page 27
ISSN 0918-7839
language English
File Version publisher
NAID 120002308327
JaLCDOI 10.18926/14973
Title Alternative Clinical significance of spa therapy in the treatment of patients with chronic obstructive pulmonary disease (COPD). A study on 520 patients with COPD admitted for last5 years.
FullText URL 068_001_007.pdf
Author Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Iwagaki, Naofumi| Yamamoto, Kazuhiko|
Abstract 1992年1月より1996年12月までの5力年間に当院へ入院した慢性閉塞性呼吸器疾患520例を対象に,疾患の種類,年齢,地域分布などについて検討を加えた。1.最近5年間に当院へ入院した呼吸器疾患患者は588例で,このうち,慢性閉塞性呼吸器疾患患者は520例(88.4%)であった。これらの慢性閉塞性呼吸器疾患のなかでは,気管支喘息が433例(83.3%)と最も多く,その他,慢性気管支炎19例,閉塞性細気管支炎33例,肺気腫35例であった。2.慢性閉塞性呼吸器疾患の年齢別検討では,鳥取県内および遠隔地(鳥取県外)いずれの症例においても,60-69才および70才以上の症例が多い傾向が見られた。3.入院患者の地域分布では,鳥取県内からの入院患者に比べ,遠隔地(鳥取県外)からの入院患者がより多く,その分布別検討では,岡山県,兵庫県,大阪腐,広島県,山口県,愛媛県からの入院患者が多い傾向が見られた。
Keywords 慢性閉塞性呼吸器疾患 (COPD) 気管支喘息 (bronchial asthma) 温泉療法 (spa therapy) 高齢患者 (aged patients) 遠隔地 (distant area)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 1
End Page 7
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308043
JaLCDOI 10.18926/14974
Title Alternative 気管支喘息におけるCTによる気腫性変化。喫煙症例と非喫煙症例の比較。
FullText URL 068_008_014.pdf
Author Tanizaki, Yoshiro| Mitsunobu, Fumihiro| Ashida, Kozo| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Nakai, Mutsuo| Akiyama, Tsuneo|
Abstract The percentage of attenuation area < -950HU (% LAA) on high resolution computed tomography (HRCT) was compared between 17 smoking and 24 nonsmoking patients with asthma. 1. FEV1/FVC value was lower in smoking patients (56.4%) than in nonsmoking patients (66.0%), however, the difference was not significant. 2. The percentage of LAA of the lung was larger in smoking patients compared with that in nonsmoking patients in all the three anatomic levels: the % LAA was 14.4% in nonsmoking and 20.3% in smoking patients at lower lung level (3cm above the top of the diaphragm). However, this was not significant. The maximal % LAA among the three lung levels on HRCT was 21.6±12.5% in smoking, and 15.7±11.9% in nonsmoking patients. This suggested that the maximal % LAA was larger in smoking patients, however, this was not significant. 3. The mean CT number of the lung on HRCT was smaller in smoking patients (-897.3HU) than in nonsmoking patients (-884.7HU). 4. Three of 4 nonsmoking patients whose % LAA was more than 30% had severe intractable asthma with long-term glucocorticoid therapy. The results suggest the possibility that smoking influences the % LAA of the lung on HRCT in asthma. It could be also speculated that % LAA is influenced by severity of asthma.
Keywords bronchial asthma FEV1 % LAA mean CT number HRCT
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 8
End Page 14
ISSN 0918-7839
language English
File Version publisher
NAID 120002308579
JaLCDOI 10.18926/14975
Title Alternative 気管支喘息におけるHRCTによるLow attenuation area(LAA)と平均CT numberとの関連
FullText URL 068_015_021.pdf
Author Mitsunobu, Fumihiro| Ashida, Kozo| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Yamamoto, Kazuhiko| Tanizaki, Yoshiro| Nakai, Mutsuo| Akiyama, Tsuneo| Hasegawa, Harumi|
Abstract The maximal percent low attenuation area < -950 HU (% LAA) among three anatomic lung levels on high resolution computed tomography (HRCT) was examined in patients with asthma, classified by the degree of % LAA, in relation to the mean CT number, % FVC of the predicted value, and FEV 1/FVC (FEV1%). 1 . The mean CT number was closely related to the degree of % LAA of the lungs. The mean CT number was significantly lower in patients with high % LAA (mean CT number-915.3HU, % LAA 37.6%) than in those with low % LAA (-852.9HU, 4.7%). 2. The FEV1% value was significantly lower in patients with high % LAA (47.8%) than in those with low % LAA (62.2%)(p<0.05). The % FVC value was also significantly lower in patients with high % LAA (77.1%) compared to the value in those with low % LAA (101.2%). The results suggest that a large volume of LAA<-950HU of the lungs can be observed in patients with asthma, and the % LAA is closely correlated with mean CT number and the values of FEV1% and % FVC.
Keywords bronchial asthma % LAA mean CT number FEV1 FVC
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 15
End Page 21
ISSN 0918-7839
language English
File Version publisher
NAID 120002308351
JaLCDOI 10.18926/14978
Title Alternative Effect of spa therapy on peak expiratory flow in patients with bronchial asthma
FullText URL 068_028_033.pdf
Author Mifune, Takashi| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine|
Abstract 気管支喘息に対する温泉療法の効果をピークフローメーターを用いて継時的(第1週,第5過,第9週)に検討した。1.軽症・中等症では,第5週で有意にピークフロー (PEF)値は上昇した.重症気管支喘息例では第9週に有意な改善を認めた。2.20%以上のPEF値の改善を認めた症例の割合は第5週では,軽症・中等症・重症群で40~50%であったが,第9週では軽症群で80%,重症群で54.5%に増加していた。中等症群では第5週と同等であった。3.第1週のPEFが200(L/m)以下の症例では第5週,第9過とPEFの有意な改善を示したが,200
Keywords bronchial asthma spa therapy peak expiratory flow (PEF)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 28
End Page 33
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308119
JaLCDOI 10.18926/14979
Title Alternative 気管支喘息症例における臨床的特徴と鼻腔・副鼻腔のCT所見の関連について
FullText URL 068_034_040.pdf
Author Mifune, Takashi| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine|
Abstract Extent of nasal and maxillary mucosa lesion was estimated in 26 asthmatics using computed tomographic scan in relation to clinical features of the disease. 1. No significant differences were present in nasal mucosal thickening between atopic and non-atopic subjects. No significant differences were also present in occupancy rate of mucosa in maxillary sinuses between the two asthma types. 2. Nasal mucosal thickening was not significant different between subjects with steroid-dependent intractable asthma (SDIA) and those without SDIA. Maxillary mucosal lesions were more extensive in subjects with SDIA than in those without SOIA. However, no significant differences were observed in occupancy rate between the two types. 3. No significant differences were observed in nasal mucosal thickenings between in subjects with and without aspirin-induced asthma (AlA). Although maxillary mucosa lesion in subjects with AlA was more extensive than that in those without AlA, the differences was not significant. 4. There was not any correlation between nasal mucosal thickening and amount of expectoration per day. However, significant differences were observed in maxillary sinus lesion between subjects with less amount (<50mℓ/day) and those with large amount of expectoration (100mℓ/day≦)(p<0.002), and between subjects with moderate amount (50-99mℓ/ day) and those with large amount of expectoration (p<0.002). The results might suggest that in asthmatics with large amount of expectoration, sinus diseases affect pathophysiology of asthma, and asthmatics with large amount of expectoration should have therapy for sinus disease to improve asthmatic status.
Keywords bronchial asthma sinusitis nasal disease CT scan expectoration
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 34
End Page 40
ISSN 0918-7839
language English
File Version publisher
NAID 120002308538
JaLCDOI 10.18926/14985
Title Alternative Dietary supplementation in bronchial asthma. Suppression of the generation of leukotrienes by N-3 fatty acids.
FullText URL 068_041_044.pdf
Author Ashida, Kozo| Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Tanizaki, Yoshiro| Tsuji, Takao| Yamamoto, Junko| Okita, Misako|
Abstract N-3系脂肪酸の気管支喘息に対する有用性が示唆されているが,その評価は定まっていない。今回,5人の気管支喘息患者に対しN-3系脂肪酸であるαリノレン酸を豊富に含有するエゴマ油を用いた食事療法を行い,臨床症状,ピークフロー値,末梢白血球からのロイコトリエン産生能,血漿リン脂質中の脂肪酸組成につき検討を行った。2週間の食事療法の前後でピークフロー値は有意な改善を示し(p<0.05),カルシウムイオノファー刺激によるロイコトリエン(LT)産生能は治療前後でLTB4が77.6ng/5×106cellsから41.6ng/5×10(6)cells(p<0.05)に,LTC4は64.0ng/5×10(6)cellsから38・8ng/5×10(6)cells(p<0.05)とともに有意な改善を認めた。また血漿リン脂質中のN-3系脂肪酸(αリノレン酸,エイコサペンタエン酸,ドコサヘキサエン酸)も有意な上昇を認めた。以上よりN-3系脂肪酸(エゴマ油)を用いた食事療法の有用性が示唆された。
Keywords シソ油 (perilla seed oil) 気管支喘息 (bronchial asthma) ロイコトリエンB4 (LTB4) ロイコトリエンC4 (LTC4) 脂肪酸 (fatty acids)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 41
End Page 44
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308166
JaLCDOI 10.18926/14986
Title Alternative 気管支喘息患者における腰椎海綿骨骨塩量と脊椎圧迫骨折の臨床的特徴
FullText URL 068_045_050.pdf
Author Tsugeno, Hirofumi| Nakai, Mutsuro| Okamoto, Makoto| Mifune, Takashi| Mitsunobu, Fumihiro| Ashida, Kozo| Hosaki, Yasuhiro| Akiyama, Tsuneo| Tsuji, Takao| Tanizaki, Yoshiro|
Abstract Clinical risk factors associated with the development of osteoporosis and vertebral fractures were evaluated in patients with asthma in relation to sex, age, and dose of glucocorticoids (GC). In 75 asthmatic patients including 44 steroid-dependent asthma, the bone mineral density (BMD) of the lumber spines was measured by quantitative computed tomography (QCT). Thirty five patients of them were followed up with radiographs over a period of 0.5 to 4 years (average: 2.6±1.3 years). The BMD was significantly lower in older (p
Keywords 気管支喘息 (bronchial asthma) 骨粗鬆症 (osteoporosis) 椎体骨折 (vertebral fracture) ステロイド療法 (glucocorticoid therapy)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 45
End Page 50
ISSN 0918-7839
language English
File Version publisher
NAID 120002308467
JaLCDOI 10.18926/14987
Title Alternative Clinical effect of spa therapy on lumbargo
FullText URL 068_051_058.pdf
Author Okamoto, Makoto| Ashida, Kozo| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Tsugeno, Hirofumi| Hosaki, Yasuhiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine|
Abstract 腰痛症患者12例を対象に温泉療法の臨床効果について検討した。臨床効果の判定は,日本整形外科学会の腰痛治療成績判定基準に基づき,自覚症状,他覚症状,及び日常生活動作などの項目を中心に,治療前後で比較検討した。その結果,自覚症状,日常生活動作,総計では,治療前に比べ治療後に有意の改善がみられた。また改善指数や改善率での検討でも温泉療法の有効性が示唆された。年齢別(60才以上と60才未満),入院期間(80日以上と80日未満)別の 検討では,65才未満の症例,80日以上の入院の症例において,改善指数,改善率が,有意差はみられなかったもののより高い傾向がみられた。
Keywords 腰痛症 (lumbargo) 温泉療法 (spa therapy) 腰痛治療判定基準 (scoring system based on the standard judgement of therapy for lumbargo)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 51
End Page 58
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308321
JaLCDOI 10.18926/14988
Title Alternative 慢性膵炎患者の全消化管通過に関する研究
FullText URL 068_059_063.pdf
Author Mizushima, Takaaki| Ochi, Koji| Matsumura, Naoki| Seno, Toshinobu| Harada, Hideo| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Abstract Abnormalities of whole gut transit could contribute to the maldigestion and digestive symptoms of chronic pancreatitis patients. Whole gut transit was measured by radiopaque markers method. Fifteen chronic pancreatitis patients (2 females, 13 males; age range 40-78 years) and 17 controls (4 females, 13 males, 32-73 years) were studied. Additionally, we also looked for evidence of autonomic neuropathy in the chronic pancreatitis patients by using cardiovascular tests. In chronic pancreatitis, whole gut transit was shorter than controls. These abnormalities were not influenced by the degree of autonomic neuropathy. We conclude that whole gut transit is shorter in chronic pancreatitis patients.
Keywords 慢性膵炎 (Chronic pancreatitis) 全消化管通過 (Whole gut transit)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 59
End Page 63
ISSN 0918-7839
language English
File Version publisher
NAID 120002308490
JaLCDOI 10.18926/14989
Title Alternative A case of eosinophilic gastroenteritis with stenosis in the colon
FullText URL 068_064_070.pdf
Author Mizushima, Takaaki| Ochi, Koji| Matsumura, Naoki| Kato, Tadahiro| Seno, Toshinobu| Harada, Hideo| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Abstract 大腸に全周性狭窄をきたした好酸球性胃腸炎の1例を報告した。症例は54才の女性で,腹痛と下痢を主訴に来院した。上部消化管検査では異常を認めなかったが,下部消化管造影検査と大腸内視鏡検査で横行結腸の全周性狭窄を認め,生検にて大腸粘膜の好酸球浸潤を認めた。貝料理の摂取にて腹痛発作が出現したが,原因抗原は同定できなかった。貝類の摂取を避けることにより,症状は消失し,末梢血液中の好酸球増多は消失した。本邦ではこれまでに124例 の報告があるが,大腸に全周性の狭窄をきたす症例は稀であり,文献的考察を加え報告する。
Keywords 好酸球性胃腸炎 (eosinophilic gastroenteropathy) 大腸 (colon) 狭窄 (stenosis)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 64
End Page 70
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308243
JaLCDOI 10.18926/14990
Title Alternative Application of hot spring pool training in outpatients with chronic diseases and its clinical evaluation
FullText URL 068_071_079.pdf
Author Nishimura, Nobuko| Kasui, Hayako| Yoshio, Keiko| Nakamura, Akemi| Ikeda, Akiko| Fukui, Yumi| Iga, Mayumi| Kuroda, Akiko|
Abstract 1996年4月より6月までの3ヵ月間に,三朝分院内の温泉プールで水泳ないし歩行訓練を受けた内科外来患者は延べ2109例(実数213例)で,外来患者総数(延べ6848例)に対する利用率は30.8%であった。これらの対象症例について,リハビリテーション受診カードにより,性別,年令別,疾患別の検討を行った。その結果,性別では女性が多く(72.3%),年齢別では50才以上の患者が多い(80.3%)傾向が見られた。また,地域別検討では,鳥取県内からの患 者が多い(88.3%)傾向であった。さらに,1996年12月より1997年1月へかけて,アンケート調査を行い(集計数;64例)継続期間,利用回数,効果を感じた期間,効果のあった症状などについて疾患別に比較検討した。その結果,慢性閉塞性肺疾患を主とした呼吸器疾患では,週に1~2回の利用回数(50.0%)で長期間(3年以上:52.9%)続けている患者が多い傾向であった。また慢性関節リウマチ,腰痛などの慢性疼痛性疾患では,訓練期間は比較的短期間であっ たが(3年以下:52.9%),利用回数は週に3~5回(38.0%)と多い傾向が見られた。温泉プール訓練では,疾患本来の症状改善に加えて,全身状態の改善,精神的リラックス,気分転換などを感じていることが示唆された。
Keywords 温水プール水泳訓練 (swimming training in a hot spring pool) 呼吸器疾患 (respiratory disease) 慢性疼痛性疾患 (chronic pain disease)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 71
End Page 79
ISSN 0918-7839
language Japanese
File Version publisher
NAID 120002308283