Author Miyahara, Daisuke| Hasegawa, Kosei| Ago, Yuko| Futagawa, Natsuko| Miyahara, Hiroyuki| Higuchi, Yousuke| Yamada, Kazuki| Tetsunaga, Tomonori| Moriwake, Tadashi| Tanaka, Hiroyuki| Tsukahara, Hirokazu|
Keywords bone development dwarfism growth infant radiography
Note This is the peer reviewed version of the following article: [Miyahara, D., Hasegawa, K., Ago, Y., Futagawa, N., Miyahara, H., Higuchi, Y., Yamada, K., Tetsunaga, T., Moriwake, T., Tanaka, H., & Tsukahara, H. (2023). Radiological characteristics of skeletal growth in neonates and infants with achondroplasia. American Journal of Medical Genetics Part A, 1–8. https://doi.org/10.1002/ajmg.a.63525], which has been published in final form at [https://doi.org/10.1002/ajmg.a.63525]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Dec. 2024.|
Published Date 2023-12-29
Publication Title American Journal of Medical Genetics Part A
Publisher Wiley
ISSN 1552-4825
NCID AA11815067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Wiley Periodicals LLC.
File Version author
PubMed ID 38158382
DOI 10.1002/ajmg.a.63525
Web of Science KeyUT 001133715300001
Related Url isVersionOf https://doi.org/10.1002/ajmg.a.63525
JaLCDOI 10.18926/AMO/66159
FullText URL 77_6_655.pdf
Author Endo, Hirosuke| Yamada, Kazuki| Tetsunaga, Tomonori| Namba, Yoshifumi| Sugimoto, Yoshihisa| Mitani, Shigeru| Nakata, Eiji| Ozaki, Toshifumi|
Abstract Most patients with developmental dysplasia of the hip (DDH) now receive closed-reduction treatment within 6 months after birth. The long-term outcomes of patients with late-detection DDH have remained unclear. We reviewed the clinical records of 18 patients who underwent Colonna capsular arthroplasty (n=8) or closed reduction (n=10) for developmental dysplasia of the hip as infants or young children and underwent total hip arthroplasty approximately in midlife. Both the Colonna capsular arthroplasty and closed reduction groups achieved good clinical results after total hip arthroplasty. However, the operating time was longer and the improvements of hip range of motion and clinical score were significantly worse in the Colonna capsular arthroplasty group than in the closed reduction group.
Keywords developmental hip dysplasia long-term follow-up closed reduction Colonna capsular arthroplasty total hip arthroplasty
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 655
End Page 663
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145941
Web of Science KeyUT 001164631200012
FullText URL fulltext.pdf
Author Sato, Yoshihiro| Tetsunaga, Tomonori| Yamada, Kazuki| Kawamura, Yoshi| Yoshida, Aki| Ozaki, Toshifumi|
Keywords hip osteoarthritis (OA) acetabular labrum vascular endothelial growth factor (VEGF) nerve growth factor (NGF) immunochemical staining
Published Date 2023-02-02
Publication Title International Journal Of Molecular Sciences
Volume volume24
Issue issue3
Publisher MDPI
Start Page 2926
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36769248
DOI 10.3390/ijms24032926
Web of Science KeyUT 000930101500001
Related Url isVersionOf https://doi.org/10.3390/ijms24032926
FullText URL fulltext.pdf
Author Hirose, Kazuki| Kuwahara, Miho| Nakata, Eiji| Tetsunaga, Tomonori| Yamada, Kazuki| Saiga, Kenta| Takigawa, Masaharu| Ozaki, Toshifumi| Kubota, Satoshi| Hattori, Takako|
Keywords hip osteoarthritis cartilage cellular communication network factor 3 (CCN3) senescence-associatedsecretory phenotype (SASP) p16 ADAMTA4/5 IL-6 TNFa aging Mankinscore weight-bearing non-weight-bearing
Published Date 2022-12-04
Publication Title International Journal Of Molecular Sciences
Volume volume23
Issue issue23
Publisher MDPI
Start Page 15311
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36499638
DOI 10.3390/ijms232315311
Web of Science KeyUT 000897995800001
Related Url isVersionOf https://doi.org/10.3390/ijms232315311
FullText URL fulltext.pdf
Author Tsuji, Hironori| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Misawa, Haruo| Oda, Yoshiaki| Takao, Shinichiro| Nishida, Keiichiro| Ozaki, Toshifumi|
Keywords caregiver burden chronic pain fear-avoidance model self-efficacy Zarit Burden Interview
Published Date 2022-09-30
Publication Title Medicine
Volume volume101
Issue issue39
Publisher Lippincott Williams & Wilkins
Start Page e30802
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36181114
DOI 10.1097/MD.0000000000030802
Web of Science KeyUT 000862039900121
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030802
JaLCDOI 10.18926/AMO/63405
FullText URL 76_2_121.pdf
Author Okazaki, Yuki| Furumatsu, Takayuki| Hiranaka, Takaaki| Kamatsuki, Yusuke| Nakata, Eiji| Tetsunaga, Tomonori| Yamane, Kentaro| Ozaki, Toshifumi|
Abstract Bone marrow edema (BME) after meniscus injury and risk factors for subchondral insufficiency fracture of the knee (SIFK) have been reported. However, their association with medial meniscus posterior root tear (MMPRT) remains unknown. We investigated the association of BME volume (BME-V), posterior shinycorner lesion (PSCL), and SIFK with MMPRT to examine the correlations between BME-V and medial meniscus extrusion (MME), PSCL and duration from injury to the time of magnetic resonance imaging (duration), and SIFK and duration. Twenty-nine patients who underwent surgery for MMPRT were included (mean age, 59.2; range, 39-84). The presence of PSCL, femoral BME-V (cm3), and SIFK grade (1-4) were evaluated. Preoperative factors, such as MME (mm) and duration (weeks), were investigated using multivariate linear/ logistic regression analyses. Multivariate linear regression analysis revealed duration as a significant factor for high-grade SIFK (p<0.01). Multivariate logistic regression analysis revealed duration as a significant factor for the presence of PSCL (odds ratio=0.94, p<0.05). A long duration of MMPRT leads to severe MME and highgrade SIFK (3 and 4), often resulting in knee arthroplasty. Early diagnosis of MMPRT and pullout repair can prevent severe MME and high-grade SIFK.
Keywords medial meniscus posterior root tear subchondral insufficiency fracture bone marrow edema meniscus extrusion
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 121
End Page 127
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503439
Web of Science KeyUT 000792374900003
JaLCDOI 10.18926/AMO/61895
FullText URL 75_2_177.pdf
Author Inoue, Madoka| Noda, Tomoyuki| Uehara, Takenori| Tetsunaga, Tomonori| Yamada, Kazuki| Saito, Taichi| Shimamura, Yasunori| Yamakawa, Yasuaki| Ozaki, Toshifumi|
Abstract This retrospective study sought to elucidate the incidence rates of roof impaction (RI) and marginal impaction (MI) and radiological and clinical outcomes of open reduction and internal fixation (ORIF) for RI and MI in geriatric acetabular fractures. The cases of 68 patients aged ≥ 65 years (mean 71 years) treated with ORIF were analyzed. MI was present in 12 fractures (67%) and an RI of the weight-bearing surface was present in 24 (46%) of the potential fracture types. Regarding the reduction quality, 54% of the reductions were graded as anatomical, 37% as imperfect, and 9% as poor. In the clinical evaluations of the 45 patients who had > 1-year follow-up (follow-up rate: 66.2%), 18% were graded as excellent, 53% as good, 16% as fair, and 13% as poor. An anatomic reduction was strongly associated with good or excellent clinical and radiological outcomes. CT was superior to radiographs for detecting the residual displacement postoperatively. Postoperative deep infection occurred in four patients. Three patients (6.7%) underwent a total hip arthroplasty conversion due to secondary osteoarthritis of the hip. We recommend ORIF as the preferred surgical treatment option for displaced acetabular fractures in elderly patients.
Keywords acetabular fracture osteosynthesis marginal impaction roof impaction elderly patient
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 177
End Page 185
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953423
NAID 120007029891
JaLCDOI 10.18926/AMO/61437
FullText URL 75_1_71.pdf
Author Sanki, Tomoaki| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Kawamura, Yoshi| Ozaki, Toshifumi|
Abstract Intra-operative acetabular fracture is a total hip arthroplasty complication that can occur during cementless cup insertion, especially in osteoporotic patients. We conducted this biomechanical study to investigate the impact resistance of the acetabulum with simulated bones of different density by drop-weight impact testing. Low- and high-density polyurethane foam blocks were used as osteoporotic and healthy bone models, respectively. Polyurethane blocks were used as the acetabular cancellous bone. Composite sheets were used as the acetabu-lum’s medial cortex. The testing revealed that the osteoporotic bone model’s impact resistance was significantly lower than that the healthy bone model’. In the healthy bone model, even thin acetabular cancellous bone with ≥ 1 mm acetabulum medial cortex was less likely to fracture. In the osteoporotic bone model, fracture was pos-sible without ≥ 1 mm medial cortex of the acetabulum and thick acetabular cancellous bone. Although impac-tion resistance differs due to bone quality, the impaction resistance in this osteoporotic bone model was equiv-alent to that healthy bone model’s when a thick medial wall was present. To avoid intra-operative acetabulum fracture, surgeons should consider both the bone quality and the thicknesses of the medial cortex and acetabu-lar cancellous bone.
Keywords intra-operative acetabular fracture drop weight impact testing total hip arthroplasty impact resistance
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-02
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 77
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649616
JaLCDOI 10.18926/AMO/61430
FullText URL 75_1_25.pdf
Author Tetsunaga, Tomonori| Tetsunaga, Tomoko| Yamada, Kazuki| Sanki, Tomoaki| Kawamura, Yoshi| Ozaki, Toshifumi|
Abstract In bipolar hemiarthroplasty (BHA), it is important to preserve soft tissue to reduce the risk of postoperative dislocation. A variety of surgical approaches for BHA are available, but extra care is needed with muscle- and tendon-preserving approaches in geriatric patients. We investigated the usefulness of BHA using a conjoined tendon-preserving posterior (CPP) approach, in which only the external obturator muscle is dissected, in geri-atric patients. We retrospectively analyzed the cases of 40 femoral neck fracture patients (10 men, 30 women) aged ≥ 80 years who underwent BHA using the CPP approach. The patients’ average age was 85.8 years (80-94 years). We examined the operation time, bleeding, preservation of short external rotator muscles, complica-tions, and stem alignment and subsidence from postoperative radiographs. Although gemellus inferior muscle injury was detected in 4 patients (10%), the hip joint stability was very excellent in all cases. There was no intraoperative fracture or postoperative dislocation. On postoperative radiographs, all femoral stems were in a neutral position. There was no stem subsidence in all 40 patients. BHA using the CPP approach appeared to be useful even in geriatric patients.
Keywords bipolar hip arthroplasty geriatric patient conjoined tendon-preserving posterior approach
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-02
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 25
End Page 30
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649610
FullText URL fulltext.pdf
Author Nakata, Eiji| Sugihara, Shinsuke| Sugawara, Yoshifumi| Nakahara, Ryuichi| Furumatsu, Takayuki| Tetsunaga, Tomonori| Kunisada, Toshiyuki| Nakanishi, Kazuo| Ozaki, Toshifumi|
Keywords bone metastasis multidisciplinary treatment skeletal-related event malignant spinal cord compression neurological deficit
Published Date 2020-02-20
Publication Title Oncology Letters
Volume volume19
Issue issue4
Publisher Spandidos Publications
Start Page 3137
End Page 3144
ISSN 1792-1074
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Nakata et al.
File Version publisher
PubMed ID 32218864
DOI 10.3892/ol.2020.11415
Web of Science KeyUT 000523763900064
Related Url isVersionOf https://doi.org/10.3892/ol.2020.11415
FullText URL fulltext.pdf
Author Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Misawa, Haruo| Takigawa, Tomoyuki| Yamane, Kentaro| Tsuji, Hironori| Takei, Yoshitaka| Ozaki, Toshifumi|
Keywords Peripheral neuropathic pain Mirogabalin Pregabalin Adverse event
Published Date 2020-05-26
Publication Title Journal of Orthopaedic Surgery and Research
Volume volume15
Issue issue1
Publisher Springer
Start Page 191
ISSN 1749-799X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 32456647
DOI 10.1186/s13018-020-01709-3
Web of Science KeyUT 000538017400002
Related Url isVersionOf https://doi.org/10.1186/s13018-020-01709-3
FullText URL fulltext.pdf
Author Tetsunaga, Tomonori| Yamada, Kazuki| Tetsunaga, Tomoko| Sanki, Tomoaki| Kawamura, Yoshi| Ozaki, Toshifumi|
Keywords Hip Navigation system Total hip replacement Retrospective study
Published Date 2020-04-15
Publication Title Journal of Orthopaedic Surgery and Research
Volume volume15
Issue issue1
Publisher BMC
Start Page 147
ISSN 1749-799X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
PubMed ID 32295628
DOI 10.1186/s13018-020-01673-y
Web of Science KeyUT 000528950200002
Related Url isVersionOf https://doi.org/10.1186/s13018-020-01673-y
FullText URL Knee_fulltext.pdf Knee_figure.pptx
Author Okazaki, Yuki| Furumatsu, Takayuki| Okazaki, Yoshiki| Masuda, Shin| Hiranaka, Takaaki| Kodama, Yuya| Kamatsuki, Yusuke| Miyazawa, Shinichi| Tetsunaga, Tomonori| Ozaki, Toshifumi|
Keywords Magnetic resonance imaging Medial meniscus Meniscus extrusion Posterior root tear Three-dimensional assessment
Published Date 2020-01-01
Publication Title The Knee
Volume volume27
Issue issue1
Publisher Elsevier
Start Page 132
End Page 139
ISSN 0968-0160
NCID AA10996272
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31882388
DOI 10.1016/j.knee.2019.09.005
Web of Science KeyUT 000519666300017
Related Url isVersionOf https://doi.org/10.1016/j.knee.2019.09.005
JaLCDOI 10.18926/AMO/57957
FullText URL 74_1_77.pdf
Author Endo, Hirosuke| Akazawa, Hirofumi| Yashiro, Masato| Yamada, Kazuki| Sanki, Tomoaki| Tetsunaga, Tomonori| Nishida, Keiichiro| Furumatsu, Takayuki| Ozaki, Toshifumi|
Abstract Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up.
Keywords idiopathic chondrolysis hip joint medication bump arthroscopy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2020-02
Volume volume74
Issue issue1
Publisher Okayama University Medical School
Start Page 77
End Page 81
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32099253
Web of Science KeyUT 000516606200012
NAID 120006795624
JaLCDOI 10.18926/AMO/57947
FullText URL 74_1_7.pdf
Author Sanki, Tomoaki| Endo, Hirosuke| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Ozaki, Toshifumi|
Abstract We investigated the relationship between the initial contact status and stress shielding in total hip arthroplasty (THA) using fit-and-fill type straight-stem implants. In addition we evaluated the clinical and radiographic outcomes. Subjects were 100 hips of 94 patients who underwent THA and were followed-up for ≥10 years. Contact areas with the femoral cortical bone were investigated according to the zonal distribution of Gruen using postoperative CT images. Depending on the number of contact areas, the patients were classified into high contact [HC], medium contact [MC], and low contact [LC] groups. Radiographic and clinical outcomes were evaluated. In the HC group (20 hips), severe stress shielding was observed in 12 hips, which was statistically significant (p=0.008). In the LC group (29 hips), mild stress shielding was observed in 27 hips which was statistically significant (p<0.001). No significant differences were observed among the 3 groups in clinical outcomes, Harris hip score (p=0.719) or Japanese Orthopedic Association (JOA) score (p=0.301). In insertion of cementless collared fit-and-fill type straight-stem implants, severe late stress shielding of the femoral bone may occur if high contact of the femoral component is achieved. However, the degree of stress shielding does not result in adverse clinical outcomes.
Keywords fit-and-fill stress shielding cementless straight stem total hip arthroplasty
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-02
Volume volume74
Issue issue1
Publisher Okayama University Medical School
Start Page 7
End Page 15
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32099243
Web of Science KeyUT 000516606200002
NAID 120006795614
FullText URL OTSR105_1_113.pdf Fig.pdf
Author Okazaki, Yuki| Furumatsu, Takayuki| Kodama, Yuya| Hino, Tomohito| Kamatsuki, Yusuke| Okazaki, Yoshiki| Masuda, Shin| Miyazawa, Shinichi| Endo, Hirosuke| Tetsunaga, Tomonori| Yamada, Kazuki| Ozaki, Toshifumi|
Keywords Magnetic resonance imaging Medial meniscus Posterior root tear Tibial rotation Transtibial pullout repair
Published Date 2019-02-28
Publication Title Orthopaedics & Traumatology: Surgery & Research
Volume volume105
Issue issue1
Publisher Elsevier
Start Page 113
End Page 117
ISSN 18770568
Content Type Journal Article
language Japanese
OAI-PMH Set 岡山大学
File Version author
PubMed ID 30482466
DOI 10.1016/j.otsr.2018.10.005
Web of Science KeyUT 000456541300019
Related Url isVersionOf https://doi.org/10.1016/j.otsr.2018.10.005