| ID | 64247 |
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| Author |
Takamura, Hiroyoshi
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
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Kinoshita, Yuya
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
Yorisue, Takefumi
Institute of Natural and Environmental Sciences, University of Hyogo
Kadota, Isao
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
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| Abstract | Geraniol, a monoterpene, and furan are structural motifs that exhibit antifouling activity. In this study, monoterpene-furan hybrid molecules with potentially enhanced antifouling activity were designed and synthesized. The nine synthetic hybrids showed antifouling activity against the cypris larvae of the barnacle Balanus (Amphibalanus) amphitrite with EC50 values of 1.65-4.70 mu g mL(-1). This activity is higher than that of geraniol and the reference furan compound. This hybridization approach to increase antifouling activity is useful and can also be extended to other active structural units.
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| Note | This is an Accepted Manuscript of an article published by Royal Society of Chemistry (RSC).
This full-text file will be available in Nov. 2023.
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| Published Date | 2022-12-20
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| Publication Title |
Organic & Biomolecular Chemistry
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| Volume | volume21
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| Issue | issue3
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| Publisher | Royal Society of Chemistry (RSC)
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| Start Page | 632
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| End Page | 638
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| ISSN | 1477-0520
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| NCID | AA1168650X
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | © The Royal Society of Chemistry 2023
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| File Version | author
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| PubMed ID | |
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| Related Url | isVersionOf https://doi.org/10.1039/d2ob02203f
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| Funder Name |
Iketani Science and Technology Foundation
Fukuoka Naohiko Memorial Foundation
Japan Society for the Promotion of Science
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| 助成番号 | JP21H01938
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