| ID | 64247 |
| フルテキストURL | |
| 著者 |
Takamura, Hiroyoshi
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
ORCID
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Kinoshita, Yuya
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
Yorisue, Takefumi
Institute of Natural and Environmental Sciences, University of Hyogo
Kadota, Isao
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
Kaken ID
publons
researchmap
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| 抄録 | Geraniol, a monoterpene, and furan are structural motifs that exhibit antifouling activity. In this study, monoterpene-furan hybrid molecules with potentially enhanced antifouling activity were designed and synthesized. The nine synthetic hybrids showed antifouling activity against the cypris larvae of the barnacle Balanus (Amphibalanus) amphitrite with EC50 values of 1.65-4.70 mu g mL(-1). This activity is higher than that of geraniol and the reference furan compound. This hybridization approach to increase antifouling activity is useful and can also be extended to other active structural units.
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| 備考 | This is an Accepted Manuscript of an article published by Royal Society of Chemistry (RSC).
This full-text file will be available in Nov. 2023.
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| 発行日 | 2022-12-20
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| 出版物タイトル |
Organic & Biomolecular Chemistry
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| 巻 | 21巻
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| 号 | 3号
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| 出版者 | Royal Society of Chemistry (RSC)
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| 開始ページ | 632
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| 終了ページ | 638
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| ISSN | 1477-0520
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| NCID | AA1168650X
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| OAI-PMH Set |
岡山大学
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| 著作権者 | © The Royal Society of Chemistry 2023
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| 論文のバージョン | author
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| PubMed ID | |
| DOI | |
| Web of Science KeyUT | |
| 関連URL | isVersionOf https://doi.org/10.1039/d2ob02203f
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| 助成機関名 |
Iketani Science and Technology Foundation
Fukuoka Naohiko Memorial Foundation
Japan Society for the Promotion of Science
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| 助成番号 | JP21H01938
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