| Author | 佐々木 朗| |
|---|---|
| Published Date | 1990-10-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/21159 |
|---|---|
| Title Alternative | An isotope study of hot springs in Nagano Prefecture |
| FullText URL | pitsr_050_017_024.pdf |
| Author | Matsubaya, Osamu| Sakai, Hitoshi| Kusakabe, Minoru| Sasaki, Akira| |
| Abstract | Water samples from 28 hotsprings and mineral springs in Nagano Prefecture, central Japan, were examined for their stable isotope ratios of hydrogen, oxygen, carbon, and sulfur. Spring waters of Kashio are highly saline and enriched in heavy isotopes of oxygen and hydrogen (δ(18)O=-2.5～-4.6‰, δD=-54～-57‰). Linear relationships among δD, δ(18)O, and Cl(-) suggest that spring waters are the mixtures of a deep brine and local surface water. Extrapolation of the linear relationships indicates that the deep brine is both isotopically and chemically very similar to the deep brine previously suggested for the springs of Arima, Takarazuka, and Ishibotoke of which δD, δ(18)O, and Cl(-) are estimated as -33‰, +8.0‰, and 44g/l, respectively. A common origin may be warranted among these postulated brines, while their provenance is yet to be worked out. The hot springs in Matsushiro are a Na-Ca-Cl type of high carbonate content. Their hydrogen and oxygen isotope ratios (δD=-71～-46‰, δ(18)O=-9.1～-2.0‰) are higher than the local surface water. On the basis of the relationships among δD, δ(18)O, and Cl(-), they are considered to be the mixtures of fossil sea water and certain water of meteoric origin of which Cl(-) is about 4g/l and δ(18)O is higher by about 3‰ than the local surface water. The latter may be meteoric water circulating in the marine sedimentary formations (Green Tuff formations) with soluble sea salts. Isotopic exchange with carbonate minerals in the formations explains its (18)O enrichment. Spring waters from Yashio and Isobe (Gunma Pref.) as well as Yunosawa and Yatate (Akita Pref.) were previously interpreted to be mixtures of fossil sea water and local surface water of low Cl(-) content. Re-examination of their data revealed that the meteoric waters responsible for these springs contain about 3g/l Cl(-), similar to the value obtained for Matsushiro. However, unlike Matsushiro, the meteoric waters in these areas are found to be isotopically similar to the local surface waters. Waters from other hot springs studied here are of simply meteoric origin, thus belonging to the GreenTuff type water previously defined. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1980-03-25 |
| Volume | volume50 |
| Start Page | 17 |
| End Page | 24 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310953 |
| JaLCDOI | 10.18926/21194 |
|---|---|
| Title Alternative | Stable isotope study of the hotsprings and volcanoes of Hokkaido, Japan |
| FullText URL | pitsr_047_055_067.pdf |
| Author | Matsubaya, Osamu| Sakai, Hitoshi| Ueda, Akira| Tsutsumi, Makoto| Kusakabe, Minoru| Sasaki, Akira| |
| Abstract | Stable isotope ratios of hydrogen, oxygen, carbon and sulfur of precipitation, thermal and mineral waters, and volcanic gases were measured. The isotopic data combined with chemical and geological information were discussed in terms of origin and evolution of the hotsprings and volcanic gases. The hotsprings along the Uchiura Bay, Oshima Peninsula are mostly near-neutral NaCl-type thermal water and may be divided into three groups : (1) thermal waters isotopically similar to the precipitation of this area, (2) those similar in D/H to the local meteoric waters but enriched by 2 to 3‰ in (18)O compared to the latter, and (3) those enriched significantly in both D and (18)O relative to the local meteoric waters. The first and second types of thermal water probably form from local meteoric water which percolates through "Green Tuff" formations and acquires dissolved chemicals from them. However, high salt concentration and the oxygen isotope shift (thesecond type) may imply that the NaCl-type water of volcanic origin might be involved. On the other hand, the waters of the third group can be explained by mixing of modern sea water into the second type thermal water (in case of Yachigashira) or by incorporation of fossil sea water of Tertiary origin into modern meteoric water (Nigorigawa). Except for Esan, Noboribetsu and Atosanupuri volcanic systems, waters from all the hotsprings and volcanic fumaroles associated with Quaternary volcanic rocks are meteoric in origin. Thermal waters at Esan, Noboribetsu and Atosanupuri have δD = -30～-50 and δ(18)O = -1～+ 3‰ and are enriched in D and (18)O relative to local meteoric water of the respective area. The origin of these waters and the mechanism (s) controlling the isotope ratios could not be made clear by the present study. Interesting is the finding that at Esan, Noboribetsu and Atosanupuri, thermal waters are enriched in D and (18)O relative to near-by fumarolic gases. The enrichment factor is 18 to 26‰ for hydrogen and 4 to 6‰ for oxygen, implying that more than one stages of liquidvapor separation are taking place in underground hydrothermal systems. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1978-03-25 |
| Volume | volume47 |
| Start Page | 55 |
| End Page | 67 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 40000321119 |
| Author | Fujioka, Shinsuke| Nishimura, Hiroaki| Nishihara, Katsunobu| Sasaki, Akira| Sunahara, Atsushi| Okuno, Tomoharu| Ueda, Nobuyoshi| Ando, Tsuyoshi| Tao, Yezheng| Shimada, Yoshinori| Hashimoto, Kazuhisa| Yamaura, Michiteru| Shigemori, Keisuke| Nakai, Mitsuo| Nagai, Keiji| Norimatsu, Takayoshi| Nishikawa, Takeshi| Miyanaga, Noriaki| Izawa, Yasukazu| Mima, Kunioki| |
|---|---|
| Published Date | 2005-11 |
| Publication Title | Physical Review Letters |
| Volume | volume95 |
| Issue | issue23 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/49257 |
|---|---|
| FullText URL | 67_1_55.pdf |
| Author | Shimo, Tsuyoshi| Nishiyama, Akiyoshi| Jinno, Tokiari| Sasaki, Akira| |
| Abstract | In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFort I osteotomy combined with a horseshoe osteotomy was used for the superior repositioning of the maxilla;then, an intraoral vertical ramus osteotomy (IVRO) and genioplasty were performed for mandibular advancement. The maxilla was acceptably impacted 8mm at the first incisor and 5mm at the first molar. Both the occlusion and facial appearance were significantly improved by this surgical-orthodontic treatment. Our results suggest that the combination of a horseshoe osteotomy with a LeFort I osteotomy is a useful technique for reliable superior repositioning of the maxilla. |
| Keywords | LeFort I osteotomy horseshoe osteotomy gummy smile |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 55 |
| End Page | 60 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439509 |
| Web of Science KeyUT | 000316829900007 |
| Author | Yamanaka, Reiko| Soga, Yoshihiko| Nawachi, Kumiko| Yanagi, Yoshinobu| Kodama, Naoki| Nakata, Takashi| Miura, Rumi| Hagawa, Misao| Takeuchi, Tetsuo| Yamane, Mieko| Morita, Manabu| Takashiba, Shogo| Asami, Jun-ichi| Minagi, Shogo| Yoshiyama, Masahiro| Shimono, Tsutomu| Kuboki, Takuo| Sasaki, Akira| Morita, Kiyoshi| |
|---|---|
| Published Date | 2009-06 |
| Publication Title | 岡山歯学会雑誌 |
| Volume | volume28 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54506 |
|---|---|
| FullText URL | 70_4_291.pdf |
| Author | Yoshioka, Norie| Shimo, Tsuyoshi| Ibaragi, Soichiro| Sasaki, Akira| |
| Abstract | Temporomandibular joint (TMJ) dislocation can occur during daily activities and negatively affect a patientʼs quality of life. Although both nonsurgical and surgical techniques have been used to treat recurrent TMJ dislocation, the former is not always successful and the latter, although having a high success rate, is invasive and requires hospitalization. Recently, autologous blood injection has been used to treat recurrent TMJ dislocation. However, this technique is not yet widely used in clinical practice. We designed this study to obtain further information as to efficacy, safety and stability of autologous blood injection for recurrent TMJ dislocation. |
| Keywords | autologous blood injection recurrent temporomandibular joint dislocation |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 294 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549675 |
| Web of Science KeyUT | 000384748600010 |
| JaLCDOI | 10.18926/AMO/55204 |
|---|---|
| FullText URL | 71_3_219.pdf |
| Author | Takakura, Hiroaki| Domae, Shohei| Ono, Toshiro| Sasaki, Akira| |
| Abstract | Anticancer drugs induce cell-cycle arrest and apoptosis not only in tumor cells, but also in immune cells. However, many preclinical and clinical findings show that some chemotherapeutic agents can improve the antitumor efficacy of immunotherapy. We immunohistochemically analyzed the degree of immune cell infiltration and the relevance of programmed cell death 1 ligand-1 (PD-L1) expression in surgically resected oral squamous cell carcinoma (OSCC) specimens from patients who had undergone pretreatment with certain chemotherapies and other patients without pretreatment. We divided the patients into the group of neoadjuvant chemotherapy (NAC) patients (n=8) and the nNAC (without NAC) patient group (n=10). We observed that NAC induced infiltrations of CD4, CD8 T cells and CD56 NK cells into the tumor microenvironment. Decreased numbers of Tregs and PD-1-positive cells were observed in the NAC group. No significant difference was observed in the degree of immune-cell infiltration between the patient groups except for CD56 NK cells in the stroma and PD-1 cells in cancer nests. Eighty percent of the nNAC specimens showed intermediate-to-strong PD-L1 protein expression, whereas 75% of the NAC specimens showed down-regulation of the PD-L1 protein, indicating the effectiveness of the chemotherapeutic treatment before surgery. |
| Keywords | oral squamous cell carcinoma programmed cell death 1 ligand-1 tumor microenvironment neoadjuvant chemotherapy immunohistochemistry |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2017-06 |
| Volume | volume71 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 219 |
| End Page | 226 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28655941 |
| FullText URL | IJO54_1_283.pdf |
|---|---|
| Author | Shimizu, Rieko| Ibaragi, Soichiro| Eguchi, Takanori| Kuwajima, Daisuke| Kodama, Shinichi| Nishioka, Takashi| Okui, Tatsuo| Obata, Kyoichi| Takabatake, Kiyofumi| Kawai, Hotaka| Ono, Kisho| Okamoto, Kuniaki| Nagatsuka, Hitoshi| Sasaki, Akira| |
| Keywords | nicotine head and neck squamous cell carcinoma lymph node metastasis cetuximab |
| Published Date | 2018-11-12 |
| Publication Title | International Journal of Oncology |
| Volume | volume54 |
| Issue | issue1 |
| Publisher | Spandidos Publications |
| Start Page | 283 |
| End Page | 294 |
| ISSN | 1019-6439 |
| NCID | AA10992511 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 30431077 |
| DOI | 10.3892/ijo.2018.4631 |
| Web of Science KeyUT | 000451845400025 |
| Related Url | isVersionOf https://doi.org/10.3892/ijo.2018.4631 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Murase, Yurika| Kishimoto, Koji| Yoshida, Shoko| Kunisada, Yuki| Kadoya, Koichi| Ibaragi, Soichiro| Sasaki, Akira| |
| Published Date | 2020-03-28 |
| Publication Title | Journal of Surgical Case Reports |
| Issue | issue3 |
| Publisher | Oxford University Press |
| Start Page | rjaa061 |
| ISSN | 2042-8812 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020. |
| File Version | publisher |
| PubMed ID | 32257103 |
| DOI | 10.1093/jscr/rjaa061 |
| Web of Science KeyUT | 000535663800034 |
| Related Url | isVersionOf https://doi.org/10.1093/jscr/rjaa061 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Kyoichi| Okui, Tatsuo| Kishimoto, Koji| Ibaragi, Soichiro| Sasaki, Akira| |
| Published Date | 2020-04-28 |
| Publication Title | Case Reports in Medicine |
| Volume | volume2020 |
| Publisher | Hindawi |
| Start Page | 4814519 |
| ISSN | 1687-9627 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 Kyoichi Obata et al. |
| File Version | publisher |
| PubMed ID | 32411253 |
| DOI | 10.1155/2020/4814519 |
| Web of Science KeyUT | 000534278000001 |
| Related Url | isVersionOf https://doi.org/10.1155/2020/4814519 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ono, Kisho| Yoshioka, Norie| Masui, Masanori| Obata, Kyoichi| Kunisada, Yuki| Okui, Tatsuo| Ibaragi, Soichiro| Kawai, Hotaka| Nagatsuka, Hitoshi| Sasaki, Akira| |
| Keywords | delayed metastasis lymphatic regurgitation neck dissection occipital lymph node oral cancer |
| Published Date | 2020-07-30 |
| Publication Title | Clinical Case Reports |
| Volume | volume8 |
| Issue | issue12 |
| Publisher | Wiley |
| Start Page | 2469 |
| End Page | 2475 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| DOI | 10.1002/ccr3.3086 |
| Web of Science KeyUT | 000553667700001 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.3086 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakamoto, Yumi| Okui, Tatsuo| Yoneda, Toshiyuki| Ryumon, Shoji| Nakamura, Tomoya| Kawai, Hotaka| Kunisada, Yuki| Ibaragi, Soichiro| Masui, Masanori| Ono, Kisho| Obata, Kyoichi| Shimo, Tsuyoshi| Sasaki, Akira| |
| Keywords | Oral squamous cell cancer HMGB1 Bone destruction Osteoclasts |
| Published Date | 2020-10-20 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume531 |
| Issue | issue3 |
| Publisher | Elsevier |
| Start Page | 422 |
| End Page | 430 |
| ISSN | 0006-291X |
| NCID | AA00564395 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors |
| File Version | publisher |
| PubMed ID | 32800556 |
| DOI | 10.1016/j.bbrc.2020.07.120 |
| Web of Science KeyUT | 000571663900011 |
| Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2020.07.120 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Okui, Tatsuo| Ibaragi, Soichiro| Ono, Kisho| Hasegawa, Kazuaki| Sasaki, Akira| |
| Keywords | peripheral ossifying fibroma |
| Published Date | 2020-11-06 |
| Publication Title | Clinical Case Reports |
| Volume | volume9 |
| Issue | issue1 |
| Publisher | Wiley |
| Start Page | 180 |
| End Page | 184 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| NAID | 120006937498 |
| DOI | 10.1002/ccr3.3494 |
| Web of Science KeyUT | 000586702500001 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.3494 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakamura, Tomoya| Okui, Tatsuo| Hasegawa, Kazuaki| Ryumon, Shoji| Ibaragi, Soichiro| Ono, Kisho| Kunisada, Yuki| Obata, Kyoichi| Masui, Masanori| Shimo, Tsuyoshi| Sasaki, Akira| |
| Keywords | head and neck cancer bone pain HMGB1 RAGE sensory neuron |
| Published Date | 2020-10-02 |
| Publication Title | Oncology Reports |
| Volume | volume44 |
| Issue | issue6 |
| Publisher | Spandidos Publications |
| Start Page | 2547 |
| End Page | 2558 |
| ISSN | 1021-335X |
| NCID | AA11016405 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Nakamuraet al. |
| File Version | publisher |
| PubMed ID | 33125145 |
| DOI | 10.3892/or.2020.7788 |
| Web of Science KeyUT | 000595257400021 |
| Related Url | isVersionOf https://doi.org/10.3892/or.2020.7788 |
| FullText URL | 2020 06 Ono K triple kd JEV.pdf |
|---|---|
| Author | Ono, Kisho| Sogawa, Chiharu| Kawai, Hotaka| Manh Tien Tran| Taha, Eman A.| Lu, Yanyin| May Wathone Oo| Okusha, Yuka| Okamura, Hirohiko| Ibaragi, Soichiro| Takigawa, Masaharu| Kozaki, Ken-Ichi| Nagatsuka, Hitoshi| Sasaki, Akira| Okamoto, Kuniaki| Calderwood, Stuart K.| Eguchi, Takanori| |
| Keywords | Extracellular vesicles epithelial‐mesenchymal transition tumour‐associated macrophage CDC37 HSP90 tetraspanin oral cancer |
| Published Date | 2020-05-31 |
| Publication Title | Journal of Extracellular Vesicles |
| Volume | volume9 |
| Issue | issue1 |
| Publisher | Taylor & Francis |
| Start Page | 1769373 |
| ISSN | 2001-3078 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Author(s). |
| File Version | publisher |
| PubMed ID | 33144925 |
| DOI | 10.1080/20013078.2020.1769373 |
| Related Url | isVersionOf https://doi.org/10.1080/20013078.2020.1769373 |
| FullText URL | fulltext20210506_2.pdf |
|---|---|
| Author | Okui, Tatsuo| Hiasa, Masahiro| Ryumon, Shoji| Ono, Kisho| Kunisada, Yuki| Ibaragi, Soichiro| Sasaki, Akira| Roodman, G. David| White, Fletcher A.| Yoneda, Toshiyuki| |
| Keywords | Breast cancer Bone pain Sensory neurons HMGB1 RAGE |
| Published Date | 2021-02-28 |
| Publication Title | Journal of Bone Oncology |
| Volume | volume26 |
| Publisher | Elsevier |
| Start Page | 100330 |
| ISSN | 22121374 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| PubMed ID | 33204606 |
| DOI | 10.1016/j.jbo.2020.100330 |
| Web of Science KeyUT | 000625035900001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jbo.2020.100330 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yoshida, Shoko| Shimo, Tsuyoshi| Takabatake, Kiyofumi| Murase, Yurika| Obata, Kyoichi| Okui, Tatsuo| Kunisada, Yuki| Ibaragi, Soichiro| Nagatsuka, Hitoshi| Sasaki, Akira| |
| Keywords | neurokinin B receptor gingival squamous cell carcinoma osteoclast |
| Published Date | 2021-06-07 |
| Publication Title | Diagnostics |
| Volume | volume11 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 1044 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34200131 |
| DOI | 10.3390/diagnostics11061044 |
| Web of Science KeyUT | 000667854200001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics11061044 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kunisada, Yuki| Yoshioka, Norie| Ibaragi, Soichiro| Okui, Tatsuo| Nagatsuka, Hitoshi| Sasaki, Akira| |
| Keywords | Mandible Multiple cafe-au-lait spots Neurofibromatosis type 1 |
| Published Date | 2021-05 |
| Publication Title | International Journal of Surgery Case Reports |
| Volume | volume82 |
| Publisher | Elsevier Sci Ltd |
| Start Page | 105883 |
| ISSN | 2210-2612 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 33878668 |
| DOI | 10.1016/j.ijscr.2021.105883 |
| Web of Science KeyUT | 000670025700017 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ijscr.2021.105883 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ono, Kisho| Okui, Tatsuo| Kunisada, Yuki| Obata, Kyoichi| Masui, Masanori| Ryumon, Shoji| Ibaragi, Soichiro| Nakamura, Tomoya| Sasaki, Akira| |
| Keywords | dentistry general surgery oncology |
| Published Date | 2021-06-24 |
| Publication Title | Clinical Case Reports |
| Volume | volume9 |
| Issue | issue6 |
| Publisher | Wiley |
| Start Page | e04321 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 34194804 |
| DOI | 10.1002/ccr3.4321 |
| Web of Science KeyUT | 000685915700045 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.4321 |
