JaLCDOI 10.18926/AMO/53028
FullText URL 68_6_379.pdf
Author Doi, Shinichiro| Kimura, Shuhei| Morizane, Yuki| Hosogi, Mika| Hosokawa, Mio| Shiode, Yusuke| Kawata, Tetsuhiro| Kondo, Eisei| Shiraga, Fumio|
Abstract We report a case of POEMS syndrome in a 20-year-old patient diagnosed after visiting an eye clinic with a chief complaint of reduced visual acuity. A male university student aged 20 years was referred to our department complaining of blurred vision in both eyes that had persisted for 1 month. He also noted headache, nausea, and paresthesia in the lower extremities around the same time. The visual acuity of his right and left eye was 20/40 and 20/20, respectively. Optic disc edema and serous retinal detachment were present. Brain magnetic resonance imaging showed no intracranial abnormalities, while elevated cerebrospinal fluid pressure, reduced nerve conduction velocity in both lower extremities, hepatosplenomegaly, M proteinemia, high blood VEGF levels, osteoblastic and osteolytic changes in the spine, and atypical plasma cells in bone lesions were noted. From the above findings, the patient was diagnosed with POEMS syndrome. He received high-dose dexamethasone, thalidomide, and radiotherapy on the sacral mass, followed by high-dose melphalan with autologous stem-cell support, and showed subsequent systemic and ophthalmologic improvement. Here, we report the youngest case ever of POEMS syndrome with ocular manifestation. If patients have optic disc edema in both eyes with no intracranial space-occupying lesion, POEMS syndrome should be considered in differential diagnosis, regardless of age.
Keywords POEMS syndrome serous retinal detachment VEGF
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 379
End Page 383
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519033
Web of Science KeyUT 000346882200009
JaLCDOI 10.18926/AMO/57716
FullText URL 73_6_517.pdf
Author Hosogi, Mika| Shiode, Yusuke| Morizane, Yuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Toshima, Shinji| Takahashi, Kosuke| Fujiwara, Atsushi| Shiraga, Fumio|
Abstract We investigated the effectiveness of a treat-and-extend regimen (TAE) of intravitreal ranibizumab injections for macular edema (ME) due to branch retinal vein occlusion (BRVO). We retrospectively examined 2-year results of 32 eyes of 32 patients who underwent TAE to treat ME due to BRVO. The patients whose treatment interval extended to ≥ 12 weeks were switched to a pro re nata regimen (PRN). For the patients whose treatment interval was <12 weeks, TAE was continued. At 2 years, 10 eyes had required no additional injections after the initial treatment period [recurrence(−) group], whereas the other 22 eyes required additional treatment [recurrence(+) group]. Among the recurrence(+) patients, 11 eyes (34.4% of total) were eventually switched from TAE to PRN; the other 11 eyes (34.4%) continued TAE for 2 years. Visual acuity and central retinal thickness were significantly improved in both the recurrence(+) and (−) groups, and there was no significant betweengroup difference in visual acuity at 2 years. Univariate analyses revealed significant differences in visual acuity (p=0.004), age (p=0.014), and vessel occlusion site (p=0.018) between these groups. Our results suggest that TAE may be effective for BRVO patients with lower visual acuity, older age, and occlusion of a major vein.
Keywords branch retinal vein occlusion macular edema anti-vascular endothelial growth factor ranibizumab treat-and-extend regimen
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-12
Volume volume73
Issue issue6
Publisher Okayama University Medical School
Start Page 517
End Page 522
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31871334
Web of Science KeyUT 000503431400007
JaLCDOI 10.18926/AMO/61909
FullText URL 75_2_249.pdf
Author Sun, Weiying| Shiode, Yusuke| Tokumasu, Kazuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Otsuka, Fumio| Morizane, Yuki|
Abstract A 79-year-old woman presented to our hospital with a 10-day history of gradually worsening binocular vision and severe backache. Further investigations revealed poor bilateral best-corrected visual acuities (BCVA), bilateral vitreous opacities, gray-white lesions scattered throughout the retina, and a left iliopsoas abscess on CT that later grew out methicillin-sensitive S. aureus. The abscess was drained and intravenous antibiotics were initiated, but the left eye additionally required intravitreal vancomycin. BCVA for both eyes normalized within 1 year. Intramuscular abscess should be considered as a possible primary lesion in cases of endogenous bacterial endophthalmitis.
Keywords endogenous bacterial endophthalmitis methicillin-sensitive Staphylococcus aureus iliopsoas abscess intravitreal injection vancomycin
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 249
End Page 253
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953434
NAID 120007029878
FullText URL fulltext.pdf
Author Takahashi, Kosuke| Kimura, Shuhei| Hosokawa, Mio Morizane| Shiode, Yusuke| Doi, Shinichiro| Matoba, Ryo| Kanzaki, Yuki| Yonekawa, Yoshihiro| Morizane, Yuki|
Keywords Case report Perfluorocarbon Retinal detachment Subretinal injection Vitreoretinal surgery
Published Date 2020-10-23
Publication Title BMC Ophthalmology
Volume volume20
Issue issue1
Publisher BMC
Start Page 427
ISSN 1471-2415
NCID AA12035369
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 33097007
DOI 10.1186/s12886-020-01698-1
Web of Science KeyUT 000586445100002
Related Url isVersionOf https://doi.org/10.1186/s12886-020-01698-1
FullText URL fulltext.pdf
Author Noda, Hiroshi| Kimura, Shuhei| Hosokawa Morizane, Mio| Shiode, Yusuke| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Kanzaki, Yuki| Fujiwara, Atsushi| Morizane, Yuki|
Published Date 2020-12-09
Publication Title Scientific Reports
Volume volume10
Issue issue1
Publisher Nature Research
Start Page 21497
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020
File Version publisher
PubMed ID 33299123
DOI 10.1038/s41598-020-78693-5
Web of Science KeyUT 000608953600006
Related Url isVersionOf https://doi.org/10.1038/s41598-020-78693-5
FullText URL fulltext.pdf
Author Fujiwara, Atsushi| Kanzaki, Yuki| Kimura, Shuhei| Hosokawa, Mio| Shiode, Yusuke| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Morizane, Yuki|
Published Date 2021-04-07
Publication Title Scientific Reports
Volume volume11
Issue issue1
Publisher Nature Research
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 33828222
NAID 120007037374
DOI 10.1038/s41598-021-87440-3
Web of Science KeyUT 000640395800029
Related Url isVersionOf https://doi.org/10.1038/s41598-021-87440-3
Author Doi, Shinichiro| Kimura, Shuhei| Saito, Shoko| Inoue, Makoto| Sakurai, Toshiya| Kobori, Akira| Hisatomi, Toshio| Imai, Hisanori| Kuriyama, Shoji| Takasu, Ippei| Hosokawa, Mio Morizane| Shiode, Yusuke| Matoba, Ryo| Suzuki, Etsuji| Morizane, Yuki|
Keywords macular intraretinal hemorrhage macular hole submacular hemorrhage retinal arterial macroaneurysm fluffy sign tissue plasminogen activator
Note This is a non-final version of an article published in final form in (Doi, Shinichiro MD, PhD*; Kimura, Shuhei MD, PhD*; Saito, Shoko MD†; Inoue, Makoto MD, PhD†; Sakurai, Toshiya MD, PhD‡; Kobori, Akira MD§; Hisatomi, Toshio MD, PhD¶; Imai, Hisanori MD, PhD**; Kuriyama, Shoji MD, PhD††; Takasu, Ippei MD‡‡; Hosokawa, Mio Morizane MD, PhD*; Shiode, Yusuke MD, PhD*; Matoba, Ryo MD, PhD*; Suzuki, Etsuji MD, PhD§§; Morizane, Yuki MD, PhD*. IMPACT OF MACULAR INTRARETINAL HEMORRHAGE AND MACULAR HOLE ON THE VISUAL PROGNOSIS OF SUBMACULAR HEMORRHAGE DUE TO RETINAL ARTERIAL MACROANEURYSM RUPTURE. Retina 43(4):p 585-593, April 2023. | DOI: 10.1097/IAE.0000000000003725).|
Published Date 2023-04
Publication Title Retina
Volume volume43
Issue issue4
Publisher Ovid Technologies (Wolters Kluwer Health)
Start Page 585
End Page 593
ISSN 0275-004X
NCID AA10639923
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023, Wolters Kluwer Health
File Version author
PubMed ID 36735920
DOI 10.1097/iae.0000000000003725
Web of Science KeyUT 000982414100014
Related Url isVersionOf https://doi.org/10.1097/iae.0000000000003725
Author Kimura, Shuhei| Hosokawa, Mio Morizane| Shiode, Yusuke| Matoba, Ryo| Kanzaki, Yuki| Goto, Yasuhito| Kanenaga, Keisuke| Suzuki, Etsuji| Morizane, Yuki|
Keywords Axial length Rhegmatogenous retinal detachment Macular detachment Fourier-domain optic biometry Ultrasound
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10384-023-01018-2| This fulltext file will be available in Aug. 2024.|
Published Date 2023-08-10
Publication Title Japanese Journal of Ophthalmology
Publisher Springer Science and Business Media LLC
ISSN 0021-5155
NCID AA00691177
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Japanese Ophthalmological Society 2023
File Version author
PubMed ID 37561309
DOI 10.1007/s10384-023-01018-2
Web of Science KeyUT 001045669100002
Related Url isVersionOf https://doi.org/10.1007/s10384-023-01018-2
Author Matoba, Ryo| Kanzaki, Yuki| Morita, Tetsuro| Kimura, Shuhei| Hosokawa, Mio Morizane| Shiode, Yusuke| Morizane, Yuki|
Keywords Epiretinal membrane Scleral buckling Retinal detachment Optical coherence tomography En face imaging Posterior vitreous detachment
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00417-023-06285-w| This fulltext file will be available in Oct. 2024.|
Published Date 2023-10-21
Publication Title Graefe's Archive for Clinical and Experimental Ophthalmology
Publisher Springer Science and Business Media LLC
ISSN 0721-832X
NCID AA10623581
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023
File Version author
PubMed ID 37864637
DOI 10.1007/s00417-023-06285-w
Web of Science KeyUT 001089648100003
Related Url isVersionOf https://doi.org/10.1007/s00417-023-06285-w
FullText URL fulltext20231114-02.pdf
Author Matoba, Ryo| Kanzaki, Yuki| Doi, Shinichiro| Kanzaki, Sayumi| Kimura, Shuhei| Hosokawa, Mio Morizane| Shiode, Yusuke| Takahashi, Kosuke| Morizane, Yuki|
Keywords Rhegmatogenous retinal detachment Epiretinal membrane Vitrectomy Internal limiting membrane En face optical coherence tomography Retinal folds
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00417-021-05118-y|
Published Date 2021-03-12
Publication Title Graefe's Archive for Clinical and Experimental Ophthalmology
Volume volume259
Issue issue9
Publisher Springer Science and Business Media LLC
Start Page 2503
End Page 2512
ISSN 0721-832X
NCID AA10623581
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021
File Version author
PubMed ID 33710473
DOI 10.1007/s00417-021-05118-y
Web of Science KeyUT 000628181800006
Related Url isVersionOf https://doi.org/10.1007/s00417-021-05118-y
JaLCDOI 10.18926/AMO/65756
FullText URL 77_4_433.pdf
Author Ono, Ryuki| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Kanzaki, Yuki| Kindo, Hiroya| Morita, Tetsuro| Morizane, Yuki|
Abstract A 23-year-old woman presented with a 1-month history of visual abnormalities in her right eye. A visual field test revealed temporal abnormalities in the right eye. Optical coherence tomography revealed an indistinct ellipsoid zone (EZ) on the B-scan image and hyporeflective areas in the EZ layer on the en face image in the right eye. We diagnosed the patient with acute zonal occult outer retinopathy. Visual field tests and B-scan images improved to almost normal at 6 months, but hyporeflective areas remained on the en face images. Thus, en face images may be more sensitive at detecting abnormalities in the outer retina than other modalities.
Keywords acute zonal occult outer retinopathy optical coherence tomography en face image ellipsoid zone
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 433
End Page 437
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635145
Web of Science KeyUT 001088434900001