| FullText URL | fulltext.pdf |
|---|---|
| Author | Hata, Nanako| Shigeyasu, Kunitoshi| Umeda, Yuzo| Yano, Shuya| Takeda, Sho| Yoshida, Kazuhiro| Fuji, Tomokazu| Yoshida, Ryuichi| Yasui, Kazuya| Umeda, Hibiki| Takahashi, Toshiaki| Kondo, Yoshitaka| Kishimoto, Hiroyuki| Mori, Yoshiko| Teraishi, Fuminori| Yamamoto, Hideki| Michiue, Hiroyuki| Nakamura, Keiichiro| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-29397-z| |
| Published Date | 2023-02-06 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 2078 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 36747029 |
| DOI | 10.1038/s41598-023-29397-z |
| Web of Science KeyUT | 000989985700018 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-29397-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Komatsu, Yasuhiro| Shigeyasu, Kunitoshi| Yano, Shuya| Takeda, Sho| Takahashi, Kazutaka| Hata, Nanako| Umeda, Hibiki| Yoshida, Kazuhiro| Mori, Yoshiko| Yasui, Kazuya| Yoshida, Ryuichi| Kondo, Yoshitaka| Kishimoto, Hiroyuki| Teraishi, Fuminori| Umeda, Yuzo| Kagawa, Shunsuke| Michiue, Hiroyuki| Tazawa, Hiroshi| Goel, Ajay| Fujiwara, Toshiyoshi| |
| Published Date | 2022-08-08 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 13540 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © TheAuthor(s)2022 |
| File Version | publisher |
| PubMed ID | 35941214 |
| DOI | 10.1038/s41598-022-17773-0 |
| Web of Science KeyUT | 000837764800013 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-17773-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Taniguchi, Fumitaka| Nyuya, Akihiro| Toshima, Toshiaki| Yasui, Kazuya| Mori, Yoshiko| Okawaki, Makoto| Kishimoto, Hiroyuki| Umeda, Yuzo| Fujiwara, Toshiyoshi| Tanioka, Hiroaki| Yamaguchi, Yoshiyuki| Goel, Ajay| Nagasaka, Takeshi| |
| Keywords | Acquired mutations BRAF colorectal cancer liquid biopsy PCR-rSSO RAS |
| Publication Title | Future Science OA |
| Publisher | Future Science Ltd. |
| Start Page | FSO757 |
| ISSN | 2056-5623 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Authors |
| File Version | publisher |
| DOI | 10.2144/fsoa-2021-0059 |
| Web of Science KeyUT | 000715287900001 |
| Related Url | isVersionOf https://doi.org/10.2144/fsoa-2021-0059 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yano, Shuya| Tazawa, Hiroshi| Kishimoto, Hiroyuki| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| Hoffman, Robert M.| |
| Keywords | cancer cell cycle fluorescent proteins FUCCI imaging adenovirus oncolytic virotherapy cancer stem cell mouse model orthotopic |
| Published Date | 2021-01-17 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue2 |
| Publisher | MDPI |
| Start Page | 879 |
| ISSN | 1422-0067 |
| NCID | AA12038549 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 33477279 |
| DOI | 10.3390/ijms22020879 |
| Web of Science KeyUT | 000611296000001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22020879 |
| Author | Ieda, Takeshi| Tazawa, Hiroshi| Okabayashi, Hiroki| Yano, Shuya| Shigeyasu, Kunitoshi| Kuroda, Shinji| Ohara, Toshiaki| Noma, Kazuhiro| Kishimoto, Hiroyuki| Nishizaki, Masahiko| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Saitou, Takashi| Imamura, Takeshi| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2019-11-8 |
| Publication Title | Scientific Reports |
| Volume | volume9 |
| Publisher | Nature Publishing Group |
| Start Page | 16378 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019 |
| File Version | publisher |
| PubMed ID | 31705021 |
| DOI | 10.1038/s41598-019-52816-z |
| Web of Science KeyUT | 000495372900001 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-019-52816-z |
| JaLCDOI | 10.18926/AMO/54817 |
|---|---|
| FullText URL | 70_6_511.pdf |
| Author | Gobara, Hideo| Hiraki, Takao| Iguchi, Toshihiro| Fujiwara, Hiroyasu| Nagasaka, Takeshi| Kishimoto, Hiroyuki| Tanaka, Takehiro| Kanazawa, Susumu| |
| Abstract | An 87-year-old Japanese man underwent percutaneous cryoablation (PCA) therapy for his renal cell tumor. We displaced the colon from the tumor using hydrodissection. Computed tomography (CT) immediately after PCA was indicative of iceball extension to the colon wall, and a discontinuous enhancement of the colon wall was observed. We therefore performed an emergency surgery. On laparotomy, we observed a dark-purple area on the affected area of the colon, and the resected specimen showed focal, deep ulceration on the mucosal surface. Photomicrography revealed mucosal necrosis, submucosal hemorrhage, and necrotic foci in the muscularis propria, corresponding to the discontinuous colon wall enhancement on CT and the deep ulceration and dark-purple area on laparotomy. He recovered from surgery and was discharged without any complications. |
| Keywords | bowel injury complication cryoablation renal cell carcinoma thermal ablation |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-12 |
| Volume | volume70 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 511 |
| End Page | 514 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28003679 |
| JaLCDOI | 10.18926/AMO/53672 |
|---|---|
| FullText URL | 69_5_267.pdf |
| Author | Inada, Ryo| Nagasaka, Takeshi| Kondo, Yoshitaka| Watanabe, Ayako| Toshima, Toshiaki| Kubota, Nobuhito| Kikuchi, Satoru| Ishida, Michihiro| Kuroda, Shinji| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time. |
| Keywords | laparoscopic surgery total proctocolectomy open proctocolectomy ulcerative colitis case-matched study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 267 |
| End Page | 273 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490023 |
| Web of Science KeyUT | 000365519600002 |
| Title Alternative | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
|---|---|
| FullText URL | 127_117.pdf |
| Author | Watanabe, Ayako| Inada, Ryo| Nagasaka, Takeshi| Yagi, Tomohiko| Matsumoto, Hijiri| Toshima, Toshiaki| Kikuchi, Satoru| Kuroda, Shinshi| Kondo, Yoshitaka| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
| Keywords | 超高齢者（extremely elderly patient） 大腸癌（colorectal cancer） 腹腔鏡手術（laparoscopic surgery） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 117 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.117 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.117 |
| NAID | 130005096253 |
| JaLCDOI | 10.18926/AMO/53340 |
|---|---|
| FullText URL | 69_2_113.pdf |
| Author | Inada, Ryo| Nagasaka, Takeshi| Toshima, Toshiaki| Mori, Yoshiko| Kondo, Yoshitaka| Kishimoto, Hiroyuki| Hiraki, Takao| Oshiro, Taihei| Kanemitsu, Yukihide| Fujiwara, Toshiyoshi| |
| Abstract | A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control. |
| Keywords | colorectal cancer recurrence total pelvic exenteration radiofrequency ablation systemic chemotherapy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 113 |
| End Page | 118 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899633 |
| Web of Science KeyUT | 000353181700006 |
| Author | Kikuchi, Satoru| Kishimoto, Hiroyuki| Tazawa, Hiroshi| Hashimoto, Yuuri| Kuroda, Shinji| Nishizaki, Masahiko| Nagasaka, Takeshi| Shirakawa, Yasuhiro| Kagawa, Shunsuke| Urata, Yasuo| Robert M Hoffman| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2014-12-19 |
| Publication Title | Molecular Therapy |
| Content Type | Journal Article |
| Author | Shigeyasu, Kunitoshi| Tazawa, Hiroshi| Hashimoto, Yuuri| Mori, Yoshiko| Nishizaki, Masahiko| Kishimoto, Hiroyuki| Nagasaka, Takeshi| Kuroda, Shinji| Urata, Yasuo| Goel, Ajay| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2014-05-28 |
| Publication Title | Gut |
| Content Type | Journal Article |
| Author | Yano, Shuya| Tazawa, Hiroshi| Hashimoto, Yuuri| Shirakawa, Yasuhiro| Kuroda, Shinji| Nishizaki, Masahiko| Kishimoto, Hiroyuki| Uno, Futoshi| Nagasaka, Takeshi| Urata, Yasuo| Kagawa, Shunsuke| Hoffman, Robert M.| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2013-12-01 |
| Publication Title | Clinical Cancer Research |
| Volume | volume19 |
| Issue | issue23 |
| Content Type | Journal Article |
| Author | Yoshida, Ryosuke| Tazawa, Hiroshi| Hashimoto, Yuuri| Yano, Shuya| Onishi, Teppei| Sasaki, Tsuyoshi| Shirakawa, Yasuhiro| Kishimoto, Hiroyuki| Uno, Futoshi| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2012-11 |
| Publication Title | Cancer Immunology, Immunotherapy |
| Volume | volume61 |
| Issue | issue11 |
| Content Type | Journal Article |
