JaLCDOI 10.18926/AMO/31995
FullText URL fulltext.pdf
Author Takeuchi, Mamoru| Morita, Kiyoshi| Iwasaki, Tatsuo| Toda, Yuichiro| Oe, Katsunori| Taga, Naoyuki| Hirakawa, Masahisa|
Abstract

To elucidate the effect of adrenomedullin (AM) on fluid homeostasis under cardiopulmonary bypass (CPB), we investigated the serial changes in plasma AM and other parameters related to fluid homeostasis in 13 children (average age, 28.2 months) with congenital heart disease during cardiac surgery under CPB. Arterial blood and urine samples were collected just after initiation of anesthesia, just before commencement of CPB, 10 min before the end of CPB, 60 min after CPB, and 24 h after operation. Plasma AM levels increased significantly 10 min before the end of CPB and decreased 24 h after operation. Urine volume increased transiently during CPB, which paralleled changes in AM. Simple regression analysis showed that plasma AM level correlated significantly with urinary vasopressin, urine volume, urinary sodium excretion, and plasma osmolarity. Stepwise regression analysis indicated that urine volume was the most significant determinant of plasma AM levels. Percent rise in AM during CPB relative to control period correlated with that of plasma brain natriuretic peptide (r = 0.57, P < 0.01). Our results suggest that AM plays an important role in fluid homeostasis under CPB in cooperation with other hormones involved in fluid homeostasis.

Keywords adrenomedullin cardiopulmonary bypass vasopressin pediatric cardiac surgery brain natriuretic peptide
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 2001-08
Volume volume55
Issue issue4
Publisher Okayama University Medical School
Start Page 245
End Page 252
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 11512567
Web of Science KeyUT 000170367200007
JaLCDOI 10.18926/AMO/54809
FullText URL 70_6_461.pdf
Author Shiozaki, Kyoko| Morimatsu, Hiroshi| Matsusaki, Takashi| Iwasaki, Tatsuo|
Abstract Many patients suffer from postoperative serious adverse events (SAEs). Here we sought to determine the incidence of SAEs, assess the accuracy of currently used scoring systems in predicting postoperative SAEs, and determine whether a combination of scoring systems would better predict postoperative SAEs. We prospectively evaluated patients who underwent major surgery. We calculated 4 scores: American Society of Anesthesiologists physical status (ASA-PS) score, the Charlson Score, the POSSUM (Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity) score, and the Surgical Apgar Score (SAS). We assessed the occurrence of SAEs. We assessed the association between each score and SAEs. We combined these scoring systems to find the best combination to predict the occurrence of SAEs. Among 284 patients, 43 suffered SAEs. All scoring systems could predict SAEs. However, their predictive power was not high (the area under the receiver operating characteristic curves [AUROC] 0.6-0.7). A combination of the ASA-PS score and the SAS was the most predictive of postoperative SAEs (AUROC 0.714). The incidence of postoperative SAEs was 15.1 . The combination of the ASA-PS score and the SAS may be a useful tool for predicting postoperative serious adverse events after major surgery.
Keywords serious adverse events preoperative assessment intraoperative assessment ASA-PS surgical Apgar score
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 461
End Page 467
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003671
Author Iwasaki, Tatsuo|
Published Date 2006-06-30
Publication Title
Content Type Thesis or Dissertation
FullText URL K0005280_fulltext.pdf
Author Ishigami, Shuta| Ohtsuki, Shinichi| Tarui, Suguru| Ousaka, Daiki| Eitoku, Takahiro| Kondo, Maiko| Okuyama, Michihiro| Kobayashi, Junko| Baba, Kenji| Arai, Sadahiko| Kawabata, Takuya| Yoshizumi, Ko| Tateishi, Atsushi| Kuroko, Yosuke| Iwasaki, Tatsuo| Sato, Shuhei| Kasahara, Shingo| Sano, Shunji| Oh, Hidemasa|
Keywords cell therapy congenital heart disease hypoplastic left heart syndrome stem cells
Note 学位審査副論文|
Published Date 2015-02
Publication Title Circulation Research
Volume volume116
Issue issue4
Publisher Lippincott Williams & Wilkins
Start Page 653
End Page 664
ISSN 00097330
NCID AA00133553
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 25403163
DOI 10.1161/circresaha.116.304671
Web of Science KeyUT 000349804900015
Related Url https://doi.org/10.1161/CIRCRESAHA.116.304671 http://ousar.lib.okayama-u.ac.jp/54044 http://ousar.lib.okayama-u.ac.jp/54263
FullText URL JACR5_1_53.pdf
Author Hayashi, Fumiaki| Nishimoto, Rei| Shimizu, Kazuyoshi| Kanazawa, Tomoyuki| Iwasaki, Tatsuo| Morimatsu, Hiroshi|
Keywords Cerebral ischemia Near-infrared spectroscopy Pediatric Minimally invasive cardiac surgery Pericardium traction
Published Date 2019-08-17
Publication Title JA Clinical Reports
Volume volume5
Issue issue51
Publisher Springer
Start Page 53
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.1186/s40981-019-0273-7
Web of Science KeyUT 000481753700001
Related Url isVersionOf https://doi.org/10.1186/s40981-019-0273-7
FullText URL fulltext.pdf
Author Tani, Makiko| Kanazawa, Tomoyuki| Shioji, Naohiro| Shimizu, Kazuyoshi| Iwasaki, Tatsuo| Morimatsu, Hiroshi|
Keywords Pneumopericardium Pericardiocentesis Recurrent nerve palsy Pleural pressure Positive pressure ventilation
Published Date 2020-10-07
Publication Title JA Clinical Reports
Volume volume6
Issue issue1
Publisher Springer
Start Page 79
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 33029685
DOI 10.1186/s40981-020-00384-x
Web of Science KeyUT 000575851100001
Related Url isVersionOf https://doi.org/10.1186/s40981-020-00384-x
FullText URL fulltext.pdf
Author Hirai, Kenta| Ousaka, Daiki| Fukushima, Yosuke| Kondo, Maiko| Eitoku, Takahiro| Shigemitsu, Yusuke| Hara, Mayuko| Baba, Kenji| Iwasaki, Tatsuo| Kasahara, Shingo| Ohtsuki, Shinichi| Oh, Hidemasa|
Note This is the author's version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science Translational Medicine on 573(12), 2020, DOI: 10.1126/scitranslmed.abb3336.|
Published Date 2020-12-09
Publication Title Science Translational Medicine
Volume volume12
Issue issue573
Publisher American Association for the Advancement of Science
Start Page eabb3336
ISSN 1946-6234
NCID AA12519139
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Authors
File Version author
PubMed ID 33298561
DOI 10.1126/scitranslmed.abb3336
Web of Science KeyUT 000597340700004
Related Url isVersionOf https://doi.org/10.1126/scitranslmed.abb3336
FullText URL fulltext.pdf
Author Kimura, Satoshi| Iwasaki, Tatsuo| Shimizu, Kazuyoshi| Kanazawa, Tomoyuki| Kawase, Hirokazu| Shioji, Naohiro| Kuroe, Yasutoshi| Isoyama, Satoshi| Morimatsu, Hiroshi|
Keywords acute kidney injury cardiac surgical procedures children creatinine point-of-care
Published Date 2019-11-24
Publication Title Health Science Reports
Volume volume3
Issue issue1
Publisher Wiley
Start Page e143
ISSN 2398-8835
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors.
File Version publisher
PubMed ID 32166189
DOI 10.1002/hsr2.143
Web of Science KeyUT 000682995400005
Related Url isVersionOf https://doi.org/10.1002/hsr2.143
FullText URL fulltext.pdf
Author Shimizu, Tatsuhiko| Kanazawa, Tomoyuki| Sakura, Takanobu| Shimizu, Kazuyoshi| Iwasaki, Tatsuo|
Keywords Focal atrial tachycardia Central extracorporeal membrane oxygenation Surgical ablation
Published Date 2021-11-03
Publication Title JA Clinical Reports
Volume volume7
Issue issue1
Publisher Springer
Start Page 81
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021.
File Version publisher
PubMed ID 34731340
DOI 10.1186/s40981-021-00481-5
Web of Science KeyUT 000714354100001
Related Url isVersionOf https://doi.org/10.1186/s40981-021-00481-5
FullText URL fulltext.pdf
Author Yasutomi, Nanako| Shimizu, Tatsuhiko| Kanazawa, Tomoyuki| Shimizu, Kazuyoshi| Iwasaki, Tatsuo| Morimatsu, Hiroshi|
Keywords Congenital heart disease Fontan circulation Esophageal varices Endoscopic injection sclerotherapy
Published Date 2022-07-05
Publication Title Ja Clinical Reports
Volume volume8
Issue issue1
Publisher Springer
Start Page 48
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35789440
DOI 10.1186/s40981-022-00538-z
Web of Science KeyUT 000820644400001
Related Url isVersionOf https://doi.org/10.1186/s40981-022-00538-z
Title Alternative The 27th Annual Meeting of the Japanese Society of Pediatric Anesthesiology
Author Iwasaki, Tatsuo|
Publication Title Journal of Okayama Medical Association
Published Date 2023-04-01
Volume volume135
Issue issue1
Start Page 49
End Page 50
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.135.49
language Japanese
Copyright Holders Copyright (c) 2023 岡山医学会
File Version publisher
DOI 10.4044/joma.135.49