Ito, Hiroshi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Feasibility of Repairing Defects Followed by Treatment with Pulmonary Hypertension-specific Drugs (Repair and Treat) in Patients with Pulmonary Hypertension Associated with Atrial Septal Defect: Study Protocol for Interventional Trial

JaLCDOI	10.18926/AMO/54600
FullText URL	70_5_397.pdf
Author	Akagi, Satoshi\| Nakamura, Kazufumi\| Akagi, Teiji\| Nakagawa, Koji\| Takaya, Yoichi\| Sarashina, Toshihiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Abstract	A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD.
Keywords	pulmonary hypertension atrial septal defect repair and treat transcatheter closure
Amo Type	Clinical Study Protocols
Publication Title	Acta Medica Okayama
Published Date	2016-10
Volume	volume70
Issue	issue5
Publisher	Okayama University Medical School
Start Page	397
End Page	400
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2016 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	27777434
Web of Science KeyUT	000388098700011

Possible Protective Effect of Remote Ischemic Preconditioning on Acute Kidney Injury Following Elective Percutaneous Coronary Intervention: Secondary Analysis of a Multicenter, Randomized Study

JaLCDOI	10.18926/AMO/61433
FullText URL	75_1_45.pdf
Author	Otsuka, Hiroaki\| Miyoshi, Toru\| Ejiri, Kentaro\| Kohno, Kunihisa\| Nakahama, Makoto\| Doi, Masayuki\| Munemasa, Mitsuru\| Murakami, Masaaki\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Abstract	Remote ischemic preconditioning (RIPC) is a promising strategy for protecting against ischemic reperfusion injury. This study is a secondary analysis of a randomized study that aimed to evaluate the effect of RIPC on the early increase in serum creatinine (SCr) following percutaneous coronary intervention (PCI), which is associ-ated with contrast-induced acute kidney injury. Patients with stable angina undergoing elective PCI were assigned to control, RIPC, and continuous infusion of nicorandil (nicorandil) groups. The endpoint of this study was the incidence of the early increase in SCr, a predictor of contrast-induced acute kidney injury, which was defined as either a > 20% or absolute increase by 0.3 mg/dl of SCr levels after 24 h of PCI. This study included 220 patients for whom a dataset of SCr values was available. The incidence of the early increase in SCr was significantly lower in the RIPC than in the control (1.3% vs 10.8%, p = 0.03) group, but was not significantly different between the nicorandil and control groups. In multivariate analysis, RIPC remained a significant fac-tor associated with a reduction in the incidence of early increase in SCr. RIPC reduces the incidence of early increase in SCr in patients with stable angina following elective PCI.
Keywords	remote ischemic preconditioning stable angina serum creatinine acute kidney injury
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2021-02
Volume	volume75
Issue	issue1
Publisher	Okayama University Medical School
Start Page	45
End Page	53
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2021 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33649613

慢性心不全治療ガイドライン

Author	Nakamura, Kazufumi\| Ito, Hiroshi\|
Published Date	2012-04-01
Publication Title	岡山医学会雑誌
Volume	volume124
Issue	issue1
Content Type	Journal Article

Open chest epicardial mapping in an asymptomatic patient with Brugada syndrome

FullText URL	fulltext.pdf
Author	Watanabe, Atsuyuki\| Morita, Hiroshi\| Kawada, Satoshi\| Tachibana, Motomi\| Morimoto, Yoshimasa\| Ito, Hiroshi\|
Keywords	Asymptomatic Brugada syndrome Catheter ablation Epicardial mapping Open chest surgery
Published Date	2019-07-16
Publication Title	HeartRhythm Case Reports
Volume	volume5
Issue	issue10
Publisher	Elsevier
Start Page	501
End Page	504
ISSN	22140271
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 Heart Rhythm Society. Published by Elsevier Inc.
File Version	publisher
PubMed ID	31700794
DOI	10.1016/j.hrcr.2019.07.003
Related Url	isVersionOf https://doi.org/10.1016/j.hrcr.2019.07.003

Pregnancy with Fontan circulation: A report of case series in Japan

FullText URL	fulltext.pdf
Author	Eto, Eriko\| Maki, Jota\| Akagi, Teiji\| Ito, Hiroshi\| Masuyama, Hisashi\|
Keywords	Anticoagulant Fontan circulation Labor analgesia Obstetrical complications Pregnancy
Published Date	2019-12-30
Publication Title	Journal of Cardiology Cases
Volume	volume21
Issue	issue4
Publisher	Elsevier
Start Page	161
End Page	163
ISSN	18785409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.
File Version	publisher
PubMed ID	32256867
DOI	10.1016/j.jccase.2019.12.005
Related Url	isVersionOf https://doi.org/10.1016/j.jccase.2019.12.005

Liver transplantation in a patient with hereditary haemorrhagic telangiectasia and pulmonary hypertension

FullText URL	fulltext.pdf
Author	Ejiri Kentaro\| Akagi, Satoshi\| Nakamura, Kazufumi\| Amioka, Naofumi\| Ichikawa, Keishi\| Yagi, Takahito\| Ito, Hiroshi\|
Keywords	Rendu-Osler-Weber syndrome arteriovenous malformation pulmonary haemorrhage
Published Date	2019-12-18
Publication Title	Pulmonary Circulation
Volume	volume9
Issue	issue4
Publisher	SAGE Publications Inc
ISSN	2045-8932
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2019.
File Version	publisher
PubMed ID	31903186
DOI	10.1177/2045894019896677
Web of Science KeyUT	000503484500001
Related Url	isVersionOf https://doi.org/10.1177/2045894019896677

Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension

FullText URL	fulltext.pdf
Author	Nakamura, Kazufumi\| Akagi, Satoshi\| Ejiri, Kentaro\| Yoshida, Masashi\| Miyoshi, Toru\| Toh, Norihisa\| Nakagawa, Koji\| Takaya, Yoichi\| Matsubara, Hiromi\| Ito, Hiroshi\|
Keywords	pulmonary arterial hypertension prostaglandin I-2 nitric oxide endothelin
Published Date	2019-11-23
Publication Title	International Journal of Molecular Sciences
Volume	volume20
Issue	issue23
Publisher	MDPI
Start Page	5885
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors.
File Version	publisher
PubMed ID	31771203
DOI	10.3390/ijms20235885
Web of Science KeyUT	000504428300067
Related Url	isVersionOf https://doi.org/10.3390/ijms20235885

Clinical Significance of Septal Malalignment for Transcatheter Closure of Atrial Septal Defect

FullText URL	fulltext.pdf
Author	Takaya, Yoichi\| Akagi, Teiji\| Nakagawa, Koji\| Nakayama, Rie\| Miki, Takashi\| Watanabe, Nobuhisa\| Toh, Norihisa\| Ito, Hiroshi\|
Published Date	2020-03-03
Publication Title	Journal of Interventional Cardiology
Volume	volume2020
Publisher	Hindawi
Start Page	6090612
ISSN	0896-4327
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Yoichi Takaya et al.
File Version	publisher
PubMed ID	32206044
DOI	10.1155/2020/6090612
Web of Science KeyUT	000522373900001
Related Url	isVersionOf https://doi.org/10.1155/2020/6090612

New Appearance of Fragmented QRS as a Predictor of Ventricular Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy

FullText URL	fulltext.pdf
Author	Ogura, Soichiro\| Nakamura, Kazufumi\| Morita, Hiroshi\| Toh, Norihisa\| Nakagawa, Koji\| Yoshida, Masashi\| Watanabe, Atsuyuki\| Nishii, Nobuhiro\| Miyoshi, Toru\| Ito, Hiroshi\|
Keywords	Electrocardiography Fragmented QRS Hospitalization Hypertrophic cardiomyopathy Ventricular arrhythmia.
Published Date	2020-02-25
Publication Title	Circulation Journal
Volume	volume84
Issue	issue3
Publisher	The Japanese Circulation Society
Start Page	487
ISSN	1346-9843
NCID	AA11591968
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 THE JAPANESE CIRCULATION SOCIETY
File Version	publisher
PubMed ID	32037379
DOI	10.1253/circj.CJ-19-0968
Web of Science KeyUT	000516606400021
Related Url	isVersionOf https://doi.org/10.1253/circj.CJ-19-0968

Impact of Right Ventricular Dilatation in Patients with Atrial Septal Defect

FullText URL	fulltext.pdf
Author	Nakayama, Rie\| Takaya, Yoichi\| Akagi, Teiji\| Nakagawa, Koji\| Watanabe, Nobuhisa\| Nobusada, Saori\| Matsushita, Toshi\| Toh, Norihisa\| Kanazawa, Susumu\| Ito, Hiroshi\|
Published Date	2020-04-28
Publication Title	Journal of Interventional Cardiology
Volume	volume2020
Publisher	Hindawi
Start Page	9509105
ISSN	0896-4327
NCID	AA10705096
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Rie Nakayama et al.
File Version	publisher
PubMed ID	32410917
DOI	10.1155/2020/9509105
Web of Science KeyUT	000533371500001
Related Url	isVersionOf https://doi.org/10.1155/2020/9509105

Effects of Eicosapentaenoic Acid on Arterial Calcification

FullText URL	fulltext.pdf
Author	Saito, Yukihiro\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	eicosapentaenoic acid atherosclerosis Klotho
Published Date	2020-07-30
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue15
Publisher	MDPI
Start Page	5455
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32751754
DOI	10.3390/ijms21155455
Web of Science KeyUT	000559183100001
Related Url	isVersionOf https://doi.org/10.3390/ijms21155455

Deficiency of CD44 prevents thoracic aortic dissection in a murine model

FullText URL	fulltext.pdf
Author	Hatipoglu, Omer F.\| Miyoshi, Toru\| Yonezawa, Tomoko\| Kondo, Megumi\| Amioka, Naofumi\| Yoshida, Masashi\| Akagi, Satoshi\| Nakamura, Kazufumi\| Hirohata, Satoshi\| Ito, Hiroshi\|
Keywords	Aneurysm Aortic diseases
Published Date	2020-04-22
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	6869
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32321956
DOI	10.1038/s41598-020-63824-9
Web of Science KeyUT	000560329100004
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-63824-9

Differences in extracellular fluid volume between acute heart failure patients with and without high systolic blood pressure

FullText URL	fulltext.pdf
Author	Namba, Yusuke\| Yunoki, Kei\| Nakamura, Kazufumi\| Ejiri, Kentaro\| Oka, Takefumi\| Ito, Hiroshi\|
Keywords	Acute heart failure High systolic blood pressure Fluid volume Oedema index
Published Date	2022-07-13
Publication Title	ESC Heart Failure
Publisher	Wiley Periodicals, Inc
ISSN	2055-5822
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	35822423
DOI	10.1002/ehf2.14067
Web of Science KeyUT	000823432100001
Related Url	isVersionOf https://doi.org/10.1002/ehf2.14067

Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus

FullText URL	fulltext.pdf
Author	Ejiri, Kentaro\| Miyoshi, Toru\| Kihara, Hajime\| Hata, Yoshiki\| Nagano, Toshihiko\| Takaishi, Atsushi\| Toda, Hironobu\| Nanba, Seiji\| Nakamura, Yoichi\| Akagi, Satoshi\| Sakuragi, Satoru\| Minagawa, Taro\| Kawai, Yusuke\| Nishii, Nobuhiro\| Fuke, Soichiro\| Yoshikawa, Masaki\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	B-type natriuretic peptide diabetes mellitus heart failure sodium-glucose cotransporter 2 inhibitor
Published Date	2020-08-18
Publication Title	Journal of the American Heart association
Volume	volume9
Issue	issue16
Publisher	Wiley
Start Page	e015103
ISSN	2047-9980
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	32805185
DOI	10.1161/JAHA.119.015103
Web of Science KeyUT	000574868200036
Related Url	isVersionOf https://doi.org/10.1161/JAHA.119.015103

Pemafibrate Prevents Rupture of Angiotensin II-Induced Abdominal Aortic Aneurysms

FullText URL	fulltext.pdf
Author	Amioka, Naofumi\| Miyoshi, Toru\| Yonezawa, Tomoko\| Kondo, Megumi\| Akagi, Satoshi\| Yoshida, Masashi\| Saito, Yukihiro\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	pemafibrate angiotensin II abdominal aortic aneurysm oxidative stress catalase
Published Date	2022-06-30
Publication Title	Frontiers In Cardiovascular Medicine
Volume	volume9
Publisher	Frontiers Media SA
Start Page	904215
ISSN	2297-055X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Amioka, Miyoshi, Yonezawa, Kondo, Akagi, Yoshida, Saito, Nakamura and Ito.
File Version	publisher
PubMed ID	35845076
DOI	10.3389/fcvm.2022.904215
Web of Science KeyUT	000826574900001
Related Url	isVersionOf https://doi.org/10.3389/fcvm.2022.904215

Residual Restrictive Right Ventricular Physiology after One-and-a-Half Ventricular Repair Conversion in Pulmonary Atresia with Intact Ventricular Septum

FullText URL	fulltext.pdf
Author	Suruga, Kazuki\| Toh, Norihisa\| Kotani, Yasuhiro\| Onishi, Hideki\| Akagi, Teiji\| Kasahara, Shingo\| Ito, Hiroshi\|
Keywords	Adult congenital heart disease Pulmonary atresia with intact ventricular septum Restrictive right ventricular physiology
Published Date	2020-12
Publication Title	CASE
Volume	volume4
Issue	issue6
Publisher	elsevier
Start Page	523
End Page	525
ISSN	2468-6441
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the American Society of Echocardiography.
File Version	publisher
PubMed ID	33376846
DOI	10.1016/j.case.2020.08.002
Related Url	isVersionOf https://doi.org/10.1016/j.case.2020.08.002

Significance of Exercise-Related Ventricular Arrhythmias in Patients With Brugada Syndrome

FullText URL	fulltext.pdf
Author	Morita, Hiroshi\| Asada, Saori T.\| Miyamoto, Masakazu\| Morimoto, Yoshimasa\| Kimura, Tomonari\| Mizuno, Tomofumi\| Nakagawa, Koji\| Watanabe, Atsuyuki\| Nishii, Nobuhiro\| Ito, Hiroshi\|
Keywords	Brugada syndrome exercise test premature ventricular contractions sudden death ventricular fibrillation
Published Date	2020-11-23
Publication Title	Journal of the American Heart Association
Volume	volume9
Issue	issue23
Publisher	Wiley
Start Page	e016907
ISSN	2047-9980
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	33222599
DOI	10.1161/JAHA.120.016907
Web of Science KeyUT	000596225900036
Related Url	isVersionOf https://doi.org/10.1161/JAHA.120.016907

Correction to: Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet

FullText URL	fulltext.pdf
Author	Yoshida, Masatoki\| Nakamura, Kazufumi\| Miyoshi, Toru\| Yoshida, Masashi\| Kondo, Megumi\| Akazawa, Kaoru\| Kimura, Tomonari\| Ohtsuka, Hiroaki\| Ohno, Yuko\| Miura, Daiji\| Ito, Hiroshi\|
Note	Correction to: Cardiovasc Diabetol (2020) 19:149 https://doi.org/10.1186/s12933-020-01132-2 \|
Published Date	2020-12-14
Publication Title	Cardiovascular Diabetology
Volume	volume19
Issue	issue1
Publisher	BMC
Start Page	213
ISSN	1475-2840
NCID	AA12050431
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020.
File Version	publisher
PubMed ID	33317516
DOI	10.1186/s12933-020-01181-7
Web of Science KeyUT	000599850200001
Related Url	isVersionOf https://doi.org/10.1186/s12933-020-01181-7

Marked Reduction of Pulmonary Artery Pressure After Registration for Lung Transplantation Is Associated With Long-Term Survival in Patients With Pulmonary Arterial Hypertension　― Cohort Study ―

FullText URL	fulltext.pdf
Author	Akagi, Satoshi\| Matsubara, Hiromi\| Nakamura, Kazufumi\| Oto, Takahiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Keywords	Lung transplantation Pulmonary artery hypertension Pulmonary artery pressure Survival
Published Date	2020-01-24
Publication Title	Circulation Journal
Volume	volume84
Issue	issue2
Publisher	The Japanese Circulation Society
Start Page	245
End Page	251
ISSN	1346-9843
NCID	AA11591968
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
DOI	10.1253/circj.CJ-19-0784
Related Url	isVersionOf https://doi.org/10.1253/circj.CJ-19-0784

Epoprostenol Therapy for Pulmonary Arterial Hypertension

JaLCDOI	10.18926/AMO/53519
FullText URL	69_3_129.pdf
Author	Akagi, Satoshi\| Nakamura, Kazufumi\| Matsubara, Hiromi\| Ogawa, Aiko\| Sarashina, Toshihiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Abstract	Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved.
Keywords	pulmonary arterial hypertension epoprostenol high-dose complications side effects
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2015-06
Volume	volume69
Issue	issue3
Publisher	Okayama University Medical School
Start Page	129
End Page	136
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2015 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	26101188
Web of Science KeyUT	000356903000001