JaLCDOI 10.18926/AMO/54808
FullText URL 70_6_455.pdf
Author Tanino, Masaaki| Kobayashi, Motomu| Sasaki, Toshihiro| Takata, Ken| Takeda, Yoshimasa| Mizobuchi, Satoshi| Morita, Kiyoshi| Nagai, Taku| Morimatsu, Hiroshi|
Abstract Postoperative cognitive dysfunction (POCD) occurs in nearly one-third of patients after non-cardiac surgery. Many animal behavior studies have investigated the effect of general anesthesia on cognitive function. However, there have been no studies examining the effects on working memory specifically, with a focus on the retention of working memory. We demonstrate here that isoflurane anesthesia induces deficits in the retention of spatial working memory in rats, as revealed by an increase in isoflurane-induced across-phase errors in the delayed spatial win-shift (SWSh) task with a 30-min delay in an 8-arm radial arm maze on post-anesthesia days (PADs) 1,2,4, and 10. A post-hoc analysis revealed a significant increase in across-phase errors on PAD 1 and recovery on PAD 10 in the isoflurane group. In contrast, within-phase errors independent of the retention of working memory were unaffected by isoflurane. These results demonstrate that isoflurane anesthesia transiently impairs the retention of spatial working memory in rats.
Keywords postoperative cognitive dysfunction isoflurane spatial working memory retention delayed spatial win-shift task
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 455
End Page 460
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003670
JaLCDOI 10.18926/AMO/60370
FullText URL 74_4_319.pdf
Author Isoyama, Satoshi| Kimura, Satoshi| Morimatsu, Hiroshi|
Abstract Little is known about the role of a strong ions in humans with respiratory abnormalities. In this study, we investigated the associations between partial carbon dioxide pressure (pCO2) and each of sodium ion (Na+) concentrations, chloride ion (Cl−) concentrations and their difference (SIDNa-Cl). Blood gas data were obtained from patients in a teaching hospital intensive care unit between August 2013 and January 2017. The association between pCO2 and SIDNa-Cl was defined as the primary outcome. The associations between pCO2 and [Cl−], [Na+] and other strong ions were secondary outcomes. pCO2 was stratified into 10 mmHg-wide bands and treated as a categorical variable for comparison. As a result, we reviewed 115,936 blood gas data points from 3,840 different ICU stays. There were significant differences in SIDNa-Cl, [Cl−], and [Na+] among all categorized pCO2 bands. The respective pCO2 SIDNa-Cl, [Cl−], and [Na+] correlation coefficients were 0.48, −0.31, and 0.08. SIDNa-Cl increased and [Cl−] decreased with pCO2, with little relationship between pCO2 and [Na+] across subsets. In conclusion, we found relatively strong correlations between pCO2 and SIDNa-Cl in the multiple blood gas datasets examined. Correlations between pCO2 and chloride concentrations, but not sodium concentrations, were further found to be moderate in these ICU data.
Keywords acid-base phenomena Stewart approach strong ion difference chlorine ion partial carbon dioxide pressure
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-08
Volume volume74
Issue issue4
Publisher Okayama University Medical School
Start Page 319
End Page 325
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32843763
Web of Science KeyUT 000562508700007
NAID 120006880209
JaLCDOI 10.18926/AMO/54814
FullText URL 70_6_497.pdf
Author Hikasa, Yukiko| Hayashi, Masao| Suzuki, Satoshi| Morimatsu, Hiroshi|
Abstract A 32-year-old woman, pregnant with twins, presented with a chief complaint of general fatigue. Her general condition had rapidly deteriorated since her last visit to the primary obstetrician; the patient was then referred to our hospital because of suspected fetal death. She underwent emergency cesarean section because fetal death had indeed occurred, and she was then admitted to the intensive care unit (ICU). On ICU admission, she was found to be in shock. Laboratory analysis revealed extreme hemoconcentration and a low albumin level, and initially, septic shock with obstetric complications was suspected. However, because she did not respond to conventional therapy but instead, rapidly developed severe generalized edema, systemic capillary leak syndrome (SCLS) was diagnosed. The patient remained in shock for several days until undergoing plasma exchange (PE), despite some earlier empirical treatments. She eventually recovered from profound shock status and was discharged from the ICU without sequelae. Among potentially effective treatments, PE seemed to be the most reasonable choice for the treatment of her SCLS.
Keywords systemic capillary leak syndrome plasma exchange pregnancy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 497
End Page 501
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003676
JaLCDOI 10.18926/AMO/57721
FullText URL 73_6_543.pdf
Author Kubo, Asuka| Shimizu, Kazuyoshi| Kuroda, Kosuke| Kanazawa, Tomoyuki| Kobayashi, Motomu| Morimatsu, Hiroshi|
Abstract We here report that a 71-year-old Japanese woman with a history of anaphylaxis induced by muscle relaxants had local anesthetic systemic toxicity (LAST) following an abdominal surgery under general anesthesia with combined spinal-epidural anesthesia without muscle relaxants. The total dosages of local anesthetics reached 0.67 mg/kg of ropivacaine and 11.5 mg/kg of lidocaine over 12.5 h to obtain sufficient muscle relaxation for surgery. Regional anesthesia is useful in cases in which muscle relaxants are to be avoided during a surgery. However, especially for a patient with risk factors and prolonged surgery, precautions should be taken to prevent LAST.
Keywords muscle relaxant-induced anaphylaxis local anesthetic systemic toxicity epidural anesthesia abdominal surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-12
Volume volume73
Issue issue6
Publisher Okayama University Medical School
Start Page 543
End Page 546
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31871339
Web of Science KeyUT 000503431400012
JaLCDOI 10.18926/AMO/57948
FullText URL 74_1_17.pdf
Author Ishii, Kenzo| Morimatsu, Hiroshi| Ono, Kazumi| Miyasho, Koji|
Abstract We performed a retrospective cohort study of 911 high-energy trauma patients who underwent chest CT scans at least twice after admission. We hypothesized that in high-energy trauma patients, a high-inspired oxygen concentration delivered after admission results in dorsal atelectasis. The study’s primary outcome was dorsal atelectasis formation diagnosed based on CT images. We defined dorsal atelectasis as the presence of atelectasis at ≥ 10 mm thick on CT images. We defined high-inspired oxygen concentration as >60% oxygen delivered between two CT scans. Four hundred sixty-five patients (51.0%) developed atelectasis according to the second CT scan, and 338 (37.1%) received a high-inspired oxygen concentration. A univariate analysis showed that the rate of the high-inspired oxygen concentration in the atelectasis group was significantly higher than that in the non-atelectasis group (43.4% vs. 30.1%, p<0.001). However, a logistic regression analysis showed that there was no significant relationship between the oxygen concentration and the formation of dorsal atelectasis (OR: 1.197, 95%CI: 0.852-1.683, p=0.30). Age, the Injury Severity Score, BMI, and smoking were found to be risk factors of dorsal atelectasis formation in high-energy trauma patients. There was no relationship between the oxygen concentration and atelectasis formation in our series of high-energy trauma patients.
Keywords trauma patient dorsal atelectasis oxygen concentration
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-02
Volume volume74
Issue issue1
Publisher Okayama University Medical School
Start Page 17
End Page 26
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32099244
Web of Science KeyUT 000516606200003
NAID 120006795615
JaLCDOI 10.18926/AMO/54809
FullText URL 70_6_461.pdf
Author Shiozaki, Kyoko| Morimatsu, Hiroshi| Matsusaki, Takashi| Iwasaki, Tatsuo|
Abstract Many patients suffer from postoperative serious adverse events (SAEs). Here we sought to determine the incidence of SAEs, assess the accuracy of currently used scoring systems in predicting postoperative SAEs, and determine whether a combination of scoring systems would better predict postoperative SAEs. We prospectively evaluated patients who underwent major surgery. We calculated 4 scores: American Society of Anesthesiologists physical status (ASA-PS) score, the Charlson Score, the POSSUM (Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity) score, and the Surgical Apgar Score (SAS). We assessed the occurrence of SAEs. We assessed the association between each score and SAEs. We combined these scoring systems to find the best combination to predict the occurrence of SAEs. Among 284 patients, 43 suffered SAEs. All scoring systems could predict SAEs. However, their predictive power was not high (the area under the receiver operating characteristic curves [AUROC] 0.6-0.7). A combination of the ASA-PS score and the SAS was the most predictive of postoperative SAEs (AUROC 0.714). The incidence of postoperative SAEs was 15.1 . The combination of the ASA-PS score and the SAS may be a useful tool for predicting postoperative serious adverse events after major surgery.
Keywords serious adverse events preoperative assessment intraoperative assessment ASA-PS surgical Apgar score
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 461
End Page 467
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003671
Author Matsumi, Junya| Morimatsu, Hiroshi| Matsusaki, Takashi| Kaku, Ryuji| Shimizu, Hiroko| Takahashi, Toru| Yagi, Takahito| Matsumi, Masaki| Morita, Kiyoshi|
Published Date 2012-02
Publication Title International Journal of Molecular Medicine
Volume volume29
Issue issue2
Content Type Journal Article
FullText URL fulltext.pdf
Author Hiroi, Kazumasa| Matsusaki, Takashi| Kaku, Ryuji| Umeda, Yuzo| Yagi, Takahito| Morimatsu, Hiroshi|
Published Date 2019-10-31
Publication Title Transplantation Proceedings
Volume volume51
Issue issue8
Publisher Elsevier
Start Page 2750
End Page 2754
ISSN 00411345
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors. Published by Elsevier Inc.
File Version publisher
PubMed ID 31563245
DOI 10.1016/j.transproceed.2019.01.199
Web of Science KeyUT 000490063000048
Related Url isVersionOf https://doi.org/10.1016/j.transproceed.2019.01.199
FullText URL JACR5_1_53.pdf
Author Hayashi, Fumiaki| Nishimoto, Rei| Shimizu, Kazuyoshi| Kanazawa, Tomoyuki| Iwasaki, Tatsuo| Morimatsu, Hiroshi|
Keywords Cerebral ischemia Near-infrared spectroscopy Pediatric Minimally invasive cardiac surgery Pericardium traction
Published Date 2019-08-17
Publication Title JA Clinical Reports
Volume volume5
Issue issue51
Publisher Springer
Start Page 53
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.1186/s40981-019-0273-7
Web of Science KeyUT 000481753700001
Related Url isVersionOf https://doi.org/10.1186/s40981-019-0273-7
FullText URL fulltext.pdf
Author Matsumoto, Naohisa| Matsusaki, Takashi| Hiroi, Kazumasa| Kaku, Ryuji| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Morimatsu, Hiroshi|
Note 11th Congress of the Andalusian-Society-of-Organ-and-Tissue-Transplantation (SATOT)|
Published Date 2020-03-31
Publication Title Transplantation Proceedings
Volume volume52
Issue issue2
Publisher Elsevier
Start Page 630
End Page 633
ISSN 00411345
NCID AA00868957
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors. Published by Elsevier Inc.
File Version publisher
PubMed ID 32029317
DOI 10.1016/j.transproceed.2019.11.032
Web of Science KeyUT 000518473000059
Related Url isVersionOf https://doi.org/10.1016/j.transproceed.2019.11.032
FullText URL fulltext.pdf
Author Matsumoto, Naohisa| Nishimoto, Rei| Matsuoka, Yoshikazu| Takeda, Yoshimasa| Morimatsu, Hiroshi|
Keywords Anesthetic management Myotonia congenita Nondystrophic myotonia Paramyotonia congenita Periodic paralysis Potassium-aggravated myotonia Skeletal muscle channelopathy Sodium-channel myotonia
Published Date 2019-11-25
Publication Title JA Clinical Reports
Volume volume5
Issue issue1
Publisher Springer
Start Page 77
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2019
File Version publisher
PubMed ID 32026975
DOI 10.1186/s40981-019-0300-8
Web of Science KeyUT 000534692000001
Related Url isVersionOf https://doi.org/10.1186/s40981-019-0300-8
FullText URL fulltext.pdf
Author Taninishi, Hideki| Matsusaki, Takashi| Morimatsu, Hiroshi|
Published Date 2020-02-28
Publication Title Scientific Reports
Volume volume10
Issue issue1
Publisher Nature
Start Page 282
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020
File Version publisher
PubMed ID 32111916
DOI 10.1038/s41598-020-60687-y
Web of Science KeyUT 000563058200004
Related Url isVersionOf https://doi.org/10.1038/s41598-020-60687-y
JaLCDOI 10.18926/AMO/53027
FullText URL 68_6_375.pdf
Author Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu|
Abstract We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care.
Keywords mouth protector tongue laceration
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 375
End Page 378
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519032
Web of Science KeyUT 000346882200008
FullText URL fulltext.pdf
Author Matsuda, Naoyuki| Nishida, Osamu| Taniguchi, Takumi| Okajima, Masaki| Morimatsu, Hiroshi| Ogura, Hiroshi| Yamada, Yoshitsugu| Nagano, Tetsuji| Ichikawa, Akira| Kakihana, Yasuyuki| J-Land 3S Study Group|
Keywords Ultra-short-acting β1-selective antagonist Heart rate Mortality Adverse events Septic shock
Published Date 2020-11
Publication Title EClinicalMedicine
Volume volume28
Publisher Elsevier
Start Page 100571
ISSN 2589-5370
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 33294804
DOI 10.1016/j.eclinm.2020.100571
Related Url isVersionOf https://doi.org/10.1016/j.eclinm.2020.100571
FullText URL fulltext.pdf
Author Tani, Makiko| Matsuoka, Yoshikazu| Sugihara, Mayu| Fujii, Ayaka| Kanazawa, Tomoyuki| Morimatsu, Hiroshi|
Keywords Esophagogastric junction carcinoma Intra-mediastinal valvuloplastic esophagogastrostomy Hemodynamic instability Tension pneumothorax Anesthetic management
Published Date 2021-02-10
Publication Title JA Clinical Reports
Volume volume7
Issue issue1
Publisher Springer
Start Page 16
ISSN 2363-9024
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2021
File Version publisher
PubMed ID 33566182
DOI 10.1186/s40981-021-00419-x
Web of Science KeyUT 000617122800001
Related Url isVersionOf https://doi.org/10.1186/s40981-021-00419-x
FullText URL fulltext.pdf
Author Oiwa, Masahiko| Kuroda, Kosuke| Kawanoue, Naoya| Morimatsu, Hiroshi|
Keywords Biomarker Clavien-Dindo classification Histidine-rich glycoprotein Intensive care unit Perioperative management Postoperative complication Predictor
Published Date 2022-07-20
Publication Title BMC Anesthesiology
Volume volume22
Issue issue1
Publisher BMC
Start Page 232
ISSN 1471-2253
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35858852
DOI 10.1186/s12871-022-01774-7
Web of Science KeyUT 000828247900001
Related Url isVersionOf https://doi.org/10.1186/s12871-022-01774-7
FullText URL fulltext.pdf
Author Kuroe, Yasutoshi| Mihara, Yuko| Okahara, Shuji| Ishii, Kenzo| Kanazawa, Tomoyuki| Morimatsu, Hiroshi|
Keywords Integrated pulmonary index Respiratory compromise Post‐anesthesia care unit
Published Date 2021-04-21
Publication Title BMC Anesthesiology
Volume volume21
Issue issue1
Publisher BMC
Start Page 123
ISSN 1471-2253
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2021
File Version publisher
PubMed ID 33882856
NAID 120007037372
DOI 10.1186/s12871-021-01338-1
Web of Science KeyUT 000643881600003
Related Url isVersionOf https://doi.org/10.1186/s12871-021-01338-1
FullText URL fulltext20210601-1.pdf
Author Soga, Yoshihiko| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi| Ashiwa, Takako| Morimatsu, Hiroshi|
Keywords perioperative management nutrition dental oral management
Note This is a post-peer-review, pre-copyedit version of an article published in Current Oral Health Reports. The final authenticated version is available online at: http://dx.doi.org/10.1007/s40496-019-0217-3.|
Published Date 2019-04-15
Publication Title Current Oral Health Reports
Volume volume6
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 70
End Page 75
ISSN 2196-3002
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
NAID 120007042397
DOI 10.1007/s40496-019-0217-3
Related Url isVersionOf https://doi.org/10.1007/s40496-019-0217-3
JaLCDOI 10.18926/AMO/53023
FullText URL 68_6_339.pdf
Author Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi|
Abstract The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ァ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care.
Keywords advance healthcare directive living will end-of-life care palliative care unit place of death
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 339
End Page 348
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519028
Web of Science KeyUT 000346882200004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/53134