JaLCDOI 10.18926/AMO/60799
FullText URL 74_5_401.pdf
Author Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi|
Abstract Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC.
Keywords differentiated thyroid carcinoma juvenile children
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-10
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 401
End Page 406
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106695
Web of Science KeyUT 000581970100004
NAID 120006892925
FullText URL fulltext.pdf
Author Tsurutani, Junji| Hara, Fumikata| Kitada, Masahiro| Takahashi, Masato| Kikawa, Yuichiro| Kato, Hiroaki| Sakata, Eiko| Naito, Yoichi| Hasegawa, Yoshie| Saito, Tsuyoshi| Iwasa, Tsutomu| Taira, Naruto| Takashima, Tsutomu| Kashiwabara, Kosuke| Aihara, Tomohiko| Mukai, Hirofumi|
Keywords Nab-paclitaxel Nanoparticle albumin–bound paclitaxel Metastatic breast cancer Solvent-base paclitaxel Chemotherapy-induced peripheral neuropathy
Published Date 2020-12-09
Publication Title The Breast
Volume volume55
Publisher Elsevier
Start Page 63
End Page 68
ISSN 0960-9776
NCID AA10844161
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
DOI 10.1016/j.breast.2020.12.002
Related Url isVersionOf https://doi.org/10.1016/j.breast.2020.12.002
FullText URL fulltext20210527_4.pdf
Author Ishikawa, Takashi| Sakamaki, Kentaro| Narui, Kazutaka| Nishimura, Hideki| Sangai, Takafumi| Tamaki, Kentaro| Hasegawa, Yoshie| Watanabe, Ken-ichi| Suganuma, Nobuyasu| Michishita, Shintaro| Sugae, Sadatoshi| Aihara, Tomohiko| Tsugawa, Koichiro| Kaise, Hirose| Taira, Naruto| Mukai, Hirofumi|
Keywords Breast cancer Febrile neutropenia Adjuvant chemotherapy Risk factors Prospective study
Published Date 2021-04-30
Publication Title The Breast
Volume volume56
Publisher Elsevier
Start Page 70
End Page 77
ISSN 09609776
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Author(s).
File Version publisher
PubMed ID 33631458
DOI 10.1016/j.breast.2021.01.005
Web of Science KeyUT 000632058800010
Related Url isVersionOf https://doi.org/10.1016/j.breast.2021.01.005
FullText URL fulltext.pdf
Author Fujihara, Miwa| Shien, Tadahiko| Shien, Kazuhiko| Suzawa, Ken| Takeda, Tatsuaki| Zhu, Yidan| Mamori, Tomoka| Otani, Yusuke| Yoshioka, Ryo| Uno, Maya| Suzuki, Yoko| Abe, Yuko| Hatono, Minami| Tsukioki, Takahiro| Takahashi, Yuko| Kochi, Mariko| Iwamoto, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi|
Keywords breast cancer YES1 T-DM1 dasatinib drug resistance
Published Date 2021-11-26
Publication Title International Journal Of Molecular Sciences
Volume volume22
Issue issue23
Publisher MDPI
Start Page 12809
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34884609
DOI 10.3390/ijms222312809
Web of Science KeyUT 000735641400001
Related Url isVersionOf https://doi.org/10.3390/ijms222312809
JaLCDOI 10.18926/AMO/64356
FullText URL 77_1_11.pdf
Author Watanabe, Satoko| Saiga, Miho| Motoki, Takayuki| Shien, Tadahiko| Taira, Naruto| Doihara, Hiroyoshi| Kimata, Yoshihiro|
Abstract The importance of a well-fitted, comfortable brassiere to overall quality of life after breast reconstruction has not been evaluated. Our aim was to determine the impact of a semi-customized brassiere on patients’ health-related quality of life after breast reconstruction. The subjects were prospective patients with mastectomy who were to undergo immediate or delayed breast reconstruction at our hospital. After surgery, a professional bra fitter sized each patient for a semi-customized brassiere and provided follow-up consultations. A self-reported questionnaire on breast aesthetics, postoperative pain, and satisfaction was used to assess the primary outcomes. Data were prospectively collected at baseline (before surgery) and at 1, 3, 6, and 12 months after surgery and analyzed. Forty-six patients (50 breasts) were included in the analysis. Consistent wearing of the brassiere reduced pain (p<0.05), with good overall satisfaction (p<0.001). Aesthetic scores on breast shape and size were higher with than without the custom brassiere at 3 months (p=0.02) and 6 months (p=0.03) after surgery. Wearing the brassiere reduced anxiety at all time points of measurement. A well-fitting brassiere ensured safety and provided a high degree of satisfaction without anxiety for patients after breast reconstruction.
Keywords breast reconstruction mastectomy brassiere professional bra fitter
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 11
End Page 19
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849141
Web of Science KeyUT 000953663800002