JaLCDOI 10.18926/AMO/64363
FullText URL 77_1_65.pdf
Author Sato, Ken| Takigawa, Nagio| Kubo, Toshio| Katayama, Hideki| Kishino, Daizo| Okada, Toshiaki| Hisamoto, Akiko| Mimoto, Junko| Ochi, Nobuaki| Yoshino, Tadashi| Ueoka, Hiroshi| Tanimoto, Mitsune| Maeda, Yoshionobu| Kiura, Katsuyuki|
Abstract We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors.
Keywords celecoxib cisplatin EGCG lung tumor polyphenon E
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 65
End Page 70
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849147
Web of Science KeyUT 000952992100004
FullText URL fulltext.pdf
Author Nishimura, Tomoka| Ichihara, Eiki| Yokoyama, Toshihide| Inoue, Koji| Tamura, Tomoki| Sato, Ken| Oda, Naohiro| Kano, Hirohisa| Kishino, Daizo| Kawai, Haruyuki| Inoue, Masaaki| Ochi, Nobuaki| Fujimoto, Nobukazu| Ichikawa, Hirohisa| Ando, Chihiro| Hotta, Katsuyuki| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords pleural effusion non-small cell carcinoma immune checkpoint inhibitors
Published Date 2022-12-14
Publication Title Cancers
Volume volume14
Issue issue24
Publisher MDPI
Start Page 6184
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36551668
DOI 10.3390/cancers14246184
Web of Science KeyUT 000900618600001
Related Url isVersionOf https://doi.org/10.3390/cancers14246184
FullText URL fulltext.pdf
Author Bu-Omer, Hani M.| Gofuku, Akio| Sato, Kenji| Miyakoshi, Makoto|
Keywords sense of agency electroencephalography (EEG) mirror visual feedback virtual reality delayed visual feedback
Published Date 2021-06-03
Publication Title Brain Sciences
Volume volume11
Issue issue6
Publisher MDPI
Start Page 743
ISSN 2076-3425
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34205076
DOI 10.3390/brainsci11060743
Web of Science KeyUT 000665308500001
Related Url isVersionOf https://doi.org/10.3390/brainsci11060743
JaLCDOI 10.18926/AMO/53027
FullText URL 68_6_375.pdf
Author Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu|
Abstract We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care.
Keywords mouth protector tongue laceration
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 375
End Page 378
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519032
Web of Science KeyUT 000346882200008
JaLCDOI 10.18926/AMO/53023
FullText URL 68_6_339.pdf
Author Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi|
Abstract The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ァ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care.
Keywords advance healthcare directive living will end-of-life care palliative care unit place of death
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 339
End Page 348
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519028
Web of Science KeyUT 000346882200004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/53134
JaLCDOI 10.18926/AMO/53021
FullText URL 68_6_323.pdf
Author Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito|
Abstract In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV.
Keywords HFOV mean lung pressure mean airway pressure
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 323
End Page 329
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519026
Web of Science KeyUT 000346882200002
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/53132
Author Nishie, Hiroyuki| Mizobuchi, Satoshi| Matsusaki, Takashi| Miyake, Asako| Kaku, Ryuji| Ishikawa, Shinichi| Sato, Kenji| Matsumi, Masaki| Kiyoshi, Morita|
Published Date 2007-05-01
Publication Title 岡山医学会雑誌
Volume volume119
Issue issue1
Content Type Journal Article
Author Inaba, Hideo| Sato, Kenji|
Published Date 1994-12-25
Publication Title 日本機械学會論文集 B編
Volume volume60
Issue issue580
Content Type Journal Article
Author Inaba, Hideo| Sato, Kenji|
Published Date 1996-01-25
Publication Title 日本機械学會論文集 B編
Volume volume62
Issue issue593
Content Type Journal Article
Author Inaba, Hideo| Sato, Kenji|
Published Date 1996-10-25
Publication Title 日本機械学會論文集 B編
Volume volume62
Issue issue602
Content Type Journal Article
Author Inaba, Hideo| Sato, Kenji|
Published Date 1997-03-25
Publication Title 日本機械学會論文集 B編
Volume volume63
Issue issue607
Content Type Journal Article
Author Inaba, Hideo| Sato, Kenji|
Published Date 1997-03-25
Publication Title 日本機械学會論文集 B編
Volume volume63
Issue issue607
Content Type Journal Article
Author Inaba, Hideo| Haruki, Naoto| Nakata, Toru| Horibe, Akihiko| Furumoto, Naoyuki| Sato, Kenji|
Published Date 2002-02-25
Publication Title 日本機械学會論文集 B編
Volume volume68
Issue issue666
Content Type Journal Article
Author Haruki, Naoto| Inaba, Hideo| Horibe, Akihiko| Tanaka, Shinji| Nakata, Toru| Sato, Kenji|
Published Date 2005-02
Publication Title 日本機械学會論文集 B編
Volume volume71
Issue issue702
Content Type Journal Article
Author 佐藤 健治|
Published Date 2000-06-30
Publication Title
Content Type Thesis or Dissertation
Title Alternative 殺菌剤、ベノミル、チウラムの土壌微生物相と2~3の土壌生息性糸状菌に及ぼす影響
FullText URL 054_0001_0008.pdf
Author Oku, Hachiro| Oki, Kazuo| Shiraishi, Tomonori| Sato, Kenji| Ouchi, Seiji|
Abstract Effects of Benomyl and Thiram on the soil microflora and some soil inhabitant fungi were studied using the_ soil (sandy loam) of the experimental field, Okayama University. Under field conditions, heavy application of Benomyl did not affect significantly the soil microflora. Thiram, however, reduced the fungal population in soil to 1/6 at the next day of treatment, but recovered to the normal level after 6 days. Under laboratory conditions, both fungicides did not affect soil microflora. Population of Benomyl-to lerant fungi was about 1/10 of the total fungi and increased slightly in the field soil by treatment with Benomyl at the later stage of experiment during June to October. Neither Thiram-tolerant fungus nor bacterium was found in both Thiram-treated and non-treated soils. A fungus highly tolerant to Benomyl was isolated and identified as Aspergillus versicolor, and found to not have the metabolic activity to degrade BCM. The absorption of BCM by the mycelia of this tolerant fungus, A. versicolor, was less than half of the BCM-sensitive one, such as Cladosporium harbarum.
Publication Title 岡山大学農学部学術報告
Published Date 1979
Volume volume54
Issue issue1
Start Page 1
End Page 8
ISSN 0474-0254
language English
File Version publisher