JaLCDOI | 10.18926/AMO/64363 |
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フルテキストURL | 77_1_65.pdf |
著者 | Sato, Ken| Takigawa, Nagio| Kubo, Toshio| Katayama, Hideki| Kishino, Daizo| Okada, Toshiaki| Hisamoto, Akiko| Mimoto, Junko| Ochi, Nobuaki| Yoshino, Tadashi| Ueoka, Hiroshi| Tanimoto, Mitsune| Maeda, Yoshionobu| Kiura, Katsuyuki| |
抄録 | We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors. |
キーワード | celecoxib cisplatin EGCG lung tumor polyphenon E |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2023-02 |
巻 | 77巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 65 |
終了ページ | 70 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36849147 |
Web of Science KeyUT | 000952992100004 |
フルテキストURL | fulltext.pdf |
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著者 | Nishimura, Tomoka| Ichihara, Eiki| Yokoyama, Toshihide| Inoue, Koji| Tamura, Tomoki| Sato, Ken| Oda, Naohiro| Kano, Hirohisa| Kishino, Daizo| Kawai, Haruyuki| Inoue, Masaaki| Ochi, Nobuaki| Fujimoto, Nobukazu| Ichikawa, Hirohisa| Ando, Chihiro| Hotta, Katsuyuki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
キーワード | pleural effusion non-small cell carcinoma immune checkpoint inhibitors |
発行日 | 2022-12-14 |
出版物タイトル | Cancers |
巻 | 14巻 |
号 | 24号 |
出版者 | MDPI |
開始ページ | 6184 |
ISSN | 2072-6694 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 by the authors. |
論文のバージョン | publisher |
PubMed ID | 36551668 |
DOI | 10.3390/cancers14246184 |
Web of Science KeyUT | 000900618600001 |
関連URL | isVersionOf https://doi.org/10.3390/cancers14246184 |
フルテキストURL | fulltext.pdf |
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著者 | Bu-Omer, Hani M.| Gofuku, Akio| Sato, Kenji| Miyakoshi, Makoto| |
キーワード | sense of agency electroencephalography (EEG) mirror visual feedback virtual reality delayed visual feedback |
発行日 | 2021-06-03 |
出版物タイトル | Brain Sciences |
巻 | 11巻 |
号 | 6号 |
出版者 | MDPI |
開始ページ | 743 |
ISSN | 2076-3425 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2021 by the authors. |
論文のバージョン | publisher |
PubMed ID | 34205076 |
DOI | 10.3390/brainsci11060743 |
Web of Science KeyUT | 000665308500001 |
関連URL | isVersionOf https://doi.org/10.3390/brainsci11060743 |
JaLCDOI | 10.18926/AMO/53027 |
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フルテキストURL | 68_6_375.pdf |
著者 | Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu| |
抄録 | We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care. |
キーワード | mouth protector tongue laceration |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2014-12 |
巻 | 68巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 375 |
終了ページ | 378 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 25519032 |
Web of Science KeyUT | 000346882200008 |
JaLCDOI | 10.18926/AMO/53023 |
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フルテキストURL | 68_6_339.pdf |
著者 | Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi| |
抄録 | The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ァ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care. |
キーワード | advance healthcare directive living will end-of-life care palliative care unit place of death |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2014-12 |
巻 | 68巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 339 |
終了ページ | 348 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 25519028 |
Web of Science KeyUT | 000346882200004 |
関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53134 |
JaLCDOI | 10.18926/AMO/53021 |
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フルテキストURL | 68_6_323.pdf |
著者 | Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito| |
抄録 | In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV. |
キーワード | HFOV mean lung pressure mean airway pressure |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2014-12 |
巻 | 68巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 323 |
終了ページ | 329 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 25519026 |
Web of Science KeyUT | 000346882200002 |
関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53132 |
著者 | 西江 宏行| 溝渕 知司| 松崎 孝| 三宅 麻子| 賀来 隆治| 石川 慎一| 佐藤 健治| 松三 昌樹| 森田 潔| |
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発行日 | 2007-05-01 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 119巻 |
号 | 1号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 佐藤 憲二| |
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発行日 | 1994-12-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 60巻 |
号 | 580号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 佐藤 憲二| |
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発行日 | 1996-01-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 62巻 |
号 | 593号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 佐藤 憲二| |
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発行日 | 1996-10-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 62巻 |
号 | 602号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 佐藤 憲二| |
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発行日 | 1997-03-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 63巻 |
号 | 607号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 佐藤 憲二| |
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発行日 | 1997-03-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 63巻 |
号 | 607号 |
資料タイプ | 学術雑誌論文 |
著者 | 稲葉 英男| 春木 直人| 中田 達| 堀部 明彦| 古本 直行| 佐藤 健次| |
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発行日 | 2002-02-25 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 68巻 |
号 | 666号 |
資料タイプ | 学術雑誌論文 |
著者 | 春木 直人| 稲葉 英男| 堀部 明彦| 田中 真司| 中田 達| 佐藤 健次| |
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発行日 | 2005-02 |
出版物タイトル | 日本機械学會論文集 B編 |
巻 | 71巻 |
号 | 702号 |
資料タイプ | 学術雑誌論文 |
著者 | 佐藤 健治| |
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発行日 | 2000-06-30 |
出版物タイトル | |
資料タイプ | 学位論文 |
タイトル(別表記) | 殺菌剤、ベノミル、チウラムの土壌微生物相と2~3の土壌生息性糸状菌に及ぼす影響 |
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フルテキストURL | 054_0001_0008.pdf |
著者 | 奥 八郎| 沖 和生| 白石 友紀| 佐藤 健二| 大内 成志| |
抄録 | Effects of Benomyl and Thiram on the soil microflora and some soil inhabitant fungi were studied using the_ soil (sandy loam) of the experimental field, Okayama University. Under field conditions, heavy application of Benomyl did not affect significantly the soil microflora. Thiram, however, reduced the fungal population in soil to 1/6 at the next day of treatment, but recovered to the normal level after 6 days. Under laboratory conditions, both fungicides did not affect soil microflora. Population of Benomyl-to lerant fungi was about 1/10 of the total fungi and increased slightly in the field soil by treatment with Benomyl at the later stage of experiment during June to October. Neither Thiram-tolerant fungus nor bacterium was found in both Thiram-treated and non-treated soils. A fungus highly tolerant to Benomyl was isolated and identified as Aspergillus versicolor, and found to not have the metabolic activity to degrade BCM. The absorption of BCM by the mycelia of this tolerant fungus, A. versicolor, was less than half of the BCM-sensitive one, such as Cladosporium harbarum. |
出版物タイトル | 岡山大学農学部学術報告 |
発行日 | 1979 |
巻 | 54巻 |
号 | 1号 |
開始ページ | 1 |
終了ページ | 8 |
ISSN | 0474-0254 |
言語 | 英語 |
論文のバージョン | publisher |