| Title Alternative | Changes of colonic mucosa caused by long-term use and discontinuation of anthraquinone |
|---|---|
| FullText URL | 129_23.pdf |
| Author | Iwano, Eiji| Iwamuro, Masaya| 岡田 裕之| |
| Abstract | Anthraquinone, an anthracene derivatives, is widely used as a purgative medicine. The long-term use of anthraquinone is known to cause melanosis coli and elevated lesions in the colon. However, the clinical course of patients who take anthraquinone over a long term and those who discontinue the drug has not been fully investigated. Here we investigated 22 patients who had colonic mucosal changes ( i.e., melanosis coli and elevated lesions) who had been taking anthraquinone for at least one year and discontinued it. We classified the elevated lesions into two subtypes:the small-lesion, which included multiple small nodules that were ＜ 2 mm in dia., and the large-lesion, which included a single or multiple nodules of ≥ 2-mm dia. We used colonoscopy to investigate the changes of colonic lesions between before and after the discontinuation of anthraquinone. The results indicated that the nodules of the small-lesion group were lymphoid follicle hyperplasia. In the large-lesion group, adenoma was most frequently observed ( n＝118) , followed by hyperplastic polyp ( n＝52) and inflammatory changes with edema ( n＝22) . Melanosis coli and elevated lesions were decreased or invisible after the discontinuation of anthraquinone. Our findings thus suggest that the long-term use of anthraquinone may cause some type of elevated lesions due to chronic inflammation. It is recommended that the use of anthraquinone be limited to a short term. |
| Keywords | アントラセン誘導体（anthracene derivatives) アントラキノン（anthraquinone） 大腸黒皮症（melanosis coli） 大腸メラノーシス（pseudomelanosis coli） リンパ濾胞過形成（lymphoid follicle hyperplasia） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-04-03 |
| Volume | volume129 |
| Issue | issue1 |
| Start Page | 23 |
| End Page | 30 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.23 |
| NAID | 130005632078 |
| JaLCDOI | 10.18926/AMO/61217 |
|---|---|
| FullText URL | 74_6_557.pdf |
| Author | Ishiguro, Mikako| Takenaka, Ryuta| Ogura, Kenichiro| Hiratsuka, Akira| Takeda, Hiromasa| Kawai, Daisuke| Tsugeno, Hirofumi| Fujiki, Shigeatsu| Okada, Hiroyuki| |
| Abstract | A 63-year-old Japanese male with stomach adenocarcinoma received oral 5-fluorouracil derivative, cisplatin and trastuzumab chemotherapy. On day 8, severe diarrhea and mucositis developed; chemotherapy was stopped. On day 14, the patient developed renal dysfunction and febrile neutropenia. He also suffered from pneumonia due to Candida albicans. Systemic symptoms improved after intensive conservative treatment. Best supportive care was continued until the patient died from gastric cancer. The dihydropyrimidine dehydroge-nase protein level was low at 3.18 U/mg protein. The result of DPYD genotyping revealed three variants at posi-tions 1615 (G > A), 1627 (A > G), and 1896 (T > C) in exons 13, 13, and 14, respectively. |
| Keywords | 5-fluorouracil dihydropyrimidine dehydrogenase deficiency DPYD variant gastric cancer |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-12 |
| Volume | volume74 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 557 |
| End Page | 562 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33361878 |
| Web of Science KeyUT | 000601203600014 |
| NAID | 120006948944 |
| Title Alternative | Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis |
|---|---|
| FullText URL | 129_111.pdf |
| Author | Sugihara, Yuusaku| Kawano, Seiji| Harada, Keita| Takashima, Shiho| Takei, Daisuke| Inokuchi, Toshihiro| Takahara, Masahiro| Hiraoka, Sakiko| Mori, Yoshiko| Kishimoto, Hiroyuki| Nagasaka, Takeshi| Okada, Hiroyuki| |
| Abstract | A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs. |
| Keywords | 家族性大腸腺腫症 (familial adenomatous polyposis) 小腸癌 (jejunal cancer) 小腸内視鏡検査 (small intestine endoscope) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-08-01 |
| Volume | volume129 |
| Issue | issue2 |
| Start Page | 111 |
| End Page | 114 |
| ISSN | 0030-1558 |
| Related Url | https://doi.org/10.4044/joma.129.111 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.111 |
| NAID | 130006039373 |
| Title Alternative | Achalasia treated with per-oral endoscopic myotomy (POEM) |
|---|---|
| FullText URL | 129_115.pdf |
| Author | Sugihara, Yuusaku| Harada, Keita| Kato, Ryo| Yamauchi, Kenji| Takashima, Shiho| Takei, Daisuke| Inokuchia, Toshihiro| Takahara, Masahiro| Kawano, Seiji| Hiraoka, Sakiko| Tanabe, Shunsuke| Noma, Kazuhiro| Shirakawa, Yasuhiro| Manabe, Noriaki| Inoue, Haruhiro| Okada, Hiroyuki| |
| Abstract | Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Patients present with dysphagia, chest pain, vomiting, and aspiration. Esophageal achalasia had traditionally been treated with esophageal achalasia balloon dilatation and the Heller-Dor method, but in recent years, the use of per-oral endoscopic myotomy (POEM) has increased. Our patient, a 39-yr-old male, began experiencing dysphagia 4 years prior to his referral to our hospital. Based on the results of esophagogastroduodenoscopy, esophageal radiography and high-resolution manometry, we made the diagnosis of esophageal achalasia (Chicago classification type I) . After informed consent from the patient and his family and approval from our hospital's ethics committee were obtained, we performed a POEM. The patient was discharged on the 4th day post-surgery. At the 1-year post-operative examination, no worsening of symptoms and no relapse were observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect and prevention of invasion. We recommend that it be considered as the first-choice treatment for achalasia. However, accessibility to the procedure itself is limited due to the few adequately trained operators worldwide. POEM should thus be performed by an expert operator at a high-volume center. |
| Keywords | POEM 食道アカラシア (esophageal achalasia) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-08-01 |
| Volume | volume129 |
| Issue | issue2 |
| Start Page | 115 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | https://doi.org/10.4044/joma.129.115 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.115 |
| NAID | 130006039377 |
| JaLCDOI | 10.18926/AMO/64365 |
|---|---|
| FullText URL | 77_1_75.pdf |
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Abstract | Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis. |
| Keywords | autoimmune gastritis esophagogastroduodenoscopy scattered lesions small white protrusions mucosal lesions |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 75 |
| End Page | 80 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849149 |
| Web of Science KeyUT | 000952973200001 |
| JaLCDOI | 10.18926/AMO/53026 |
|---|---|
| FullText URL | 68_6_369.pdf |
| Author | Iwamuro, Masaya| Miyashima, Yuichi| Yoshioka, Takahiro| Murata, Toshihiro| Miyabe, Yoshio| Kawai, Yoshinari| Urata, Haruo| Shiraha, Hidenori| Okada, Hiroyuki| Yamamoto, Kazuhide| |
| Abstract | A 67-year-old Japanese man underwent enterotomy because of enterolith ileus. Component analysis by infrared spectroscopy revealed that the enterolith was composed of a high concentration of deoxycholic acid. We further analyzed and compared the ultrastructure of the enterolith and a commercially available powdered form of deoxycholic acid by means of scanning electron microscopy and energy dispersive X-ray spectroscopy. Energy dispersive X-ray spectroscopy analysis revealed that the ratios of carbon and oxygen in the enterolith were equal to those in the deoxycholic acid powder. Scanning electron microscopy analysis showed rectangular prism-shaped particles on the surface of the enterolith. This structure was similar to that of the deoxycholic acid powder. The surgically removed enterolith had a twisted and coiled appearance. Possible mechanisms underlying the formation of this unique form are discussed. |
| Keywords | enterolith deoxycholic acid scanning electron microscopy infrared spectroscopy energy dispersive X-ray spectroscopy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 369 |
| End Page | 374 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519031 |
| Web of Science KeyUT | 000346882200007 |
| Author | Okada, Hiroyuki| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Journal Article |
| FullText URL | DLD51_1_168.pdf |
|---|---|
| Author | Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Okada, Hiroyuki| |
| Published Date | 2019-01-31 |
| Publication Title | Digestive and Liver Disease |
| Volume | volume51 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 168 |
| ISSN | 15908658 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved. |
| File Version | author |
| PubMed ID | 30145054 |
| DOI | 10.1016/j.dld.2018.07.031 |
| Web of Science KeyUT | 000454119300026 |
| Related Url | isVersionOf https://doi.org/10.1016/j.dld.2018.07.031 |
| FullText URL | CGH17_6_56.pdf fig.pdf |
|---|---|
| Author | Tomoda, Takeshi| Kato, Hironari| Okada, Hiroyuki| |
| Published Date | 2019-05-31 |
| Publication Title | Clinical Gastroenterology and Hepatology |
| Volume | volume17 |
| Issue | issue6 |
| Publisher | Elsevier Science |
| Start Page | e56 |
| End Page | e57 |
| ISSN | 15423565 |
| NCID | AA11845942 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the AGA Institute |
| File Version | author |
| PubMed ID | 29857148 |
| DOI | 10.1016/j.cgh.2018.05.032 |
| Web of Science KeyUT | 000464657100006 |
| Related Url | isVersionOf https://doi.org/10.1016/j.cgh.2018.05.032 |
| FullText URL | Gastroenterology156_6_1753.pdf fig.pdf |
|---|---|
| Author | Tomoda, Takeshi| Kato, Hironari| Ueki, Toru| Akimoto, Yutaka| Hata, Hidenori| Fujii, Masakuni| Harada, Ryo| Ogawa, Tsuneyoshi| Wato, Masaki| Takatani, Masahiro| Matsubara, Minoru| Kawai, Yoshinari| Okada, Hiroyuki| |
| Keywords | Drug Inflammation Pancreas Smooth-Muscle Relaxant |
| Published Date | 2019-05-31 |
| Publication Title | Gastroenterology |
| Volume | volume156 |
| Issue | issue6 |
| Publisher | W B SAUNDERS CO-ELSEVIER |
| Start Page | 1753 |
| End Page | 1760 |
| ISSN | 00165085 |
| NCID | AA0065394X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30772342 |
| DOI | 10.1053/j.gastro.2019.01.267 |
| Web of Science KeyUT | 10.1053/j.gastro.2019.01.267 |
| Related Url | isVersionOf https://doi.org/10.1053/j.gastro.2019.01.267 |
| FullText URL | JGastroenterol_54_11_1019.pdf Table.pdf Figure 1.jpg Figure 2.jpg Figure 3A.tif Figure 3B.tif supplemental figure 1.jpg |
|---|---|
| Author | Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Tanaka, Noriyuki| Kato, Hironari| Horiguchi, Shigeru| Yoshida, Ryuichi| Umeda, Yuzo| Fushimi, Soichiro| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki| |
| Keywords | Immunohistochemistry PD-L1 Pancreatic cancer |
| Note | This fulltext will be available in Apr 2020| |
| Published Date | 2019-04-29 |
| Publication Title | Journal of Gastroenterology |
| Volume | volume54 |
| Issue | issue11 |
| Start Page | 1019 |
| End Page | 1028 |
| ISSN | 09441174 |
| NCID | AA10988015 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31032528 |
| DOI | 10.1007/s00535-019-01586-6 |
| Web of Science KeyUT | 000492169400008 |
| Related Url | isVersionOf https://doi.org/10.1007/s00535-019-01586-6 |
| FullText URL | GRP_8159072.pdf |
|---|---|
| Author | Iwamuro, Masaya| Aoyama, Yuki| Suzuki, Seiyuu| Kobayashi, Sayo| Toyokawa, Tatsuya| Moritou, Yuki| Hori, Shinichiro| Matsueda, Kazuhiro| Yoshioka, Masao| Tanaka, Takehiro| Okada, Hiroyuki| |
| Published Date | 2019-09-08 |
| Publication Title | Gastroenterology Research and Practice |
| Publisher | Hindawi |
| Start Page | 8159072 |
| ISSN | 1687-6121 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2019 Masaya Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 31582972 |
| DOI | 10.1155/2019/8159072 |
| Web of Science KeyUT | 000487588000001 |
| Related Url | isVersionOf https://doi.org/10.1016/bs.aiip.2019.01.001 |
| FullText URL | CRGM_2019_5742672.pdf |
|---|---|
| Author | Iwamuro, Masaya| Urata, Haruo| Hirata, Shoichiro| Ueki, Toru| Hanabata, Tetsuro| Takeda, Sho| Teraoka, Akira| Okada, Hiroyuki| |
| Published Date | 2019-05-23 |
| Publication Title | Case Reports in Gastrointestinal Medicine |
| Publisher | HINDAWI |
| Start Page | 5742672 |
| ISSN | 20906528 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2019 Masaya Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 31240139 |
| DOI | 10.1155/2019/5742672 |
| Web of Science KeyUT | 000470161500001 |
| Related Url | isVersionOf https://doi.org/10.1155/2019/5742672 |
| FullText URL | ecancermedicalscience2019_933.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Nishida, Kenji| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki| |
| Keywords | follicular gastritis gastric neoplasms gastrointestinal endoscope mucosa-associated lymphoid tissue lymphoma nodular gastritis |
| Published Date | 2019-06-03 |
| Publication Title | ecancermedicalscience |
| Volume | volume13 |
| Publisher | CANCER INTELLIGENCE |
| Start Page | 933 |
| ISSN | 1754-6605 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © the authors |
| File Version | publisher |
| PubMed ID | 31281430 |
| DOI | 10.3332/ecancer.2019.933 |
| Web of Science KeyUT | 000472729000001 |
| Related Url | isVersionOf https://doi.org/10.3332/ecancer.2019.933 |
| FullText URL | JMU46_4_449.pdf |
|---|---|
| Author | Takada, Saimon| Kato, Hironari| Saragai, Yosuke| Muro, Shinichiro| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tanaka, Noriyuki| Okada, Hiroyuki| |
| Keywords | Contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) Pancreatic neuroendocrine neoplasm (PNEN) Time–intensity curve (TIC) analysis |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Journal of Medical Ultrasonics. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10396-019-00967-x.| |
| Published Date | 2019-08-03 |
| Publication Title | Journal of Medical Ultrasonics |
| Volume | volume46 |
| Issue | issue4 |
| Publisher | Springer |
| Start Page | 449 |
| End Page | 458 |
| ISSN | 1346-4523 |
| NCID | AA11563281 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31377939 |
| DOI | 10.1007/s10396-019-00967-x |
| Web of Science KeyUT | 000487923000010 |
| Related Url | isVersionOf https://doi.org/10.1007/s10396-019-00967-x |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki| |
| Keywords | ulcerative colitis salicylates mesalazine sulfasalazine |
| Published Date | 2019-12-02 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume8 |
| Issue | issue12 |
| Publisher | MDPI |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31810227 |
| DOI | 10.3390/jcm8122109 |
| Web of Science KeyUT | 000506640400082 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm8122109 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchida, Daisuke| Kato, Hironari| Matsumoto, Kazuyuki| Ishihara, Yuki| Matsumi, Akihiro| Saragai, Yosuke| Takada, Saimon| Yabe, Shuntaro| Muro, Shinichiro| Tomoda, Takeshi| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Keywords | Endoscopic ultrasound Diagnostic screening program Pancreatic diseases Biliary tract diseases |
| Published Date | 2019-12-18 |
| Publication Title | BMC Gastroenterology |
| Volume | volume19 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 220 |
| ISSN | 1471-230X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2019 |
| File Version | publisher |
| PubMed ID | 31852458 |
| DOI | 10.1186/s12876-019-1141-7 |
| Web of Science KeyUT | 000510482800002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-019-1141-7 |
| Title Alternative | Efficacy of Helicobacter pylori eradication followed by the administration of a proton pump inhibitor (PPI) or PPI plus a prokinetic in H. pylori-positive patients with dyspepsia |
|---|---|
| FullText URL | 131_139.pdf |
| Author | 三浦 公| Iwamuro, Masaya| Toyokawa, Tatsuya| Takenaka, Ryuta| Inoue, Masafumi| Ito, Mamoru| Okada, Hiroyuki| |
| Abstract | To investigate whether treatment comprised of Helicobacter pylori eradication followed by the administration of a proton pump inhibitor (PPI) alone and a dual treatment with a PPI plus a prokinetic agent helps relieve symptoms, we treated 26 patients with H. pylori infection and dyspepsia with the sequential treatment and assessed their symptoms. Scores for gastroesophageal reflux disease (GERD) and dyspepsia in a modified F-scale were significantly improved after the eradication of H. pylori, and symptoms were completely relieved in 13 patients. The remaining 13 patients received 4-week treatment with the PPI rabeprazole, and their GERD scores significantly improved after the treatment. The symptoms of five patients completely disappeared ; the other eight patients required dual treatment with a PPI plus the prokinetic acotiamide. Early satiety tended to be relieved after the dual treatment, but the improvement was not significant. Thus, in patients with dyspepsia and an H. pylori infection, the H. pylori should be eradicated first. The administration of a PPI is useful in patients with GERD symptoms, and a PPI+ acotiamide may be beneficial for residual symptoms of early satiety. |
| Keywords | 機能性ディスペプシア (functional dyspepsia) ヘリコバクター・ピロリ (Helicobacter pylori) プロトンポンプ阻害剤 (proton pomp inhibitor) 消化管運動機能改善剤 (acotiamide) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2019-12-02 |
| Volume | volume131 |
| Issue | issue3 |
| Start Page | 139 |
| End Page | 143 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.131.139 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2019 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.131.139 |
| NAID | 130007782646 |
| FullText URL | fulltext.pdf table.pdf |
|---|---|
| Author | Tomoda, Takeshi| Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuuki| Saragai, Yousuke| Yamazaki, Tatsuhiro| chida, Daisuke| atsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Keywords | Malignant biliary obstruction Double-balloon enteroscope Endoscopic retrograde cholangiopancreatography Surgically altered anatomy |
| Note | This fulltext is aailable in Jan. 2021.| |
| Published Date | 2020-01-16 |
| Publication Title | Surgical Endoscopy |
| ISSN | 09302794 |
| NCID | AA10750363 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31950273 |
| DOI | 10.1007/s00464-020-07385-y |
| Web of Science KeyUT | 000507705600001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00464-020-07385-y |
| JaLCDOI | 10.18926/AMO/52900 |
|---|---|
| FullText URL | 68_5_307.pdf |
| Author | Muro, Shinichiro| Nasu, Junichiro| Harada, Ryo| Matsubara, Minoru| Nakarai, Asuka| Kanzaki, Hiromitsu| Tsutsumi, Kouichiro| Kato, Hironari| Tanaka, Takehiro| Fujiwara, Hiroyasu| Uno, Masatoshi| Okada, Hiroyuki| Yamamoto, Kazuhide| |
| Abstract | A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia. |
| Keywords | malignant insulinoma hypoglycemia liver metastases transarterial embolization neuroendocrinetumor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-10 |
| Volume | volume68 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 311 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25338488 |
| Web of Science KeyUT | 000343269300008 |
