FullText URL | kokugo_colophon.pdf |
---|---|
Author | 岡山大学教育学部国語研究会| |
Publication Title | 岡山大学国語研究 |
Published Date | 2017-03-20 |
Volume | volume31 |
ISSN | 2189-5414 |
language | 日本語 |
File Version | publisher |
FullText URL | poalas_033_contents_eng.pdf |
---|---|
Author | Okayama Association for Laboratory Animal Science| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
language | 日本語 |
File Version | publisher |
FullText URL | poalas_033_contents.pdf |
---|---|
Author | 岡山実験動物研究会| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
language | 日本語 |
File Version | publisher |
Title Alternative | Breeding and genetics of mutant strains and domestication of wildlife for laboratory animal science |
---|---|
FullText URL | poalas_033_002.pdf |
Author | Oda, Sen-ichi| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 2 |
End Page | 2 |
language | 日本語 |
File Version | publisher |
Title Alternative | Pharmacokinetic analysis of drug absorption following nasal application to rats |
---|---|
FullText URL | poalas_033_003_007.pdf |
Author | 古林 呂之| |
Abstract | Since a drug applied to the nose in an in vivo physiologic condition is translocated to the gastrointestinal (GI) tract by mucociliary clearance (MC), the drug undergoes absorption both from the nasal cavity and from the GI tract. The detailed MC of the rat was examined, using inulin as a marker of the applied solution. Inulin disappeared monoexponentially from the nasal cavity, indicating that the MC can be assumed to follow first-order kinetics. In the proposed kinetic model, the fractional absorption of the drug following nasal application is predicted as the sum of fractional absorption from the nasal cavity and fractional absorption from the GI tract, both of which are estimated indirectly from the permeability to the Caco-2 monolayer. This kinetic model is the first estimation system for nasal drug absorption based on drug disposition after nasal application and is useful for the development of nasal dosage forms. |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 3 |
End Page | 7 |
language | 日本語 |
File Version | publisher |
Title Alternative | Overview and future perspectives of studies on the mechanisms underlying appetite regulation in chickens |
---|---|
FullText URL | poalas_033_008_010.pdf |
Author | Honda, Kazuhisa| |
Abstract | Broiler chickens eat more feed than layer chickens. As a result, broiler chickens grow faster than layer chickens. However, excessive accumulation of body fat in broiler chickens has been a serious problem in the poultry industry in recent decades. Therefore, the appetite regulatory system of chickens has been a focus of research among poultry scientists. Lines of evidence suggest that the physiological role of peripheral adiposity hormones, such as leptin and insulin, and gut hormones, such as ghrelin, are different between mammals and chickens. Thus, species specificity make it difficult to understand the mechanisms underlying the regulation of food intake in chickens. Here I provide an overview of recent findings in this field and future perspectives. |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 8 |
End Page | 10 |
language | 日本語 |
File Version | publisher |
Title Alternative | Dissecting the hierarchy and lineage of mesenchymal stem cells by mouse genetics |
---|---|
FullText URL | poalas_033_015_017.pdf |
Author | Takarada, Takeshi| |
Abstract | Determination of stem cell hierarchy/lineage is indispensable for a better understanding and augmentation of many aspects of medical sciences, including the mechanisms of tissue development and maintenance of tissue homeostasis, as well as disease development. It also has implications in the field of tissue regeneration for medical treatments and disease modeling for drug discovery using iPS technology. Mesenchymal stem cells are multipotent stem cell that can differentiate into various type of cells including osteoblasts, adipocytes, myocytes and chondrocytes. Runt-related transcription factor 2 (Runx2) is an essential transcriptional regulator of osteoblast differentiation. Runx2 deficiency in Prx1+-derived cells (Runx2prx1−/− mice) resulted in defective intramembranous ossification. Double-positive cells for Prx1-GFP and stem cell antigen-1 (Sca1) (Prx1+Sca1+ cells) in the calvaria expressed Runx2 at lower levels and were more homogeneous and primitive as compared with Prx1+Sca1− cells. Our results suggest that osteoblast differentiation in vivo may begin at the Prx1+Sca1+ MSC stage with sequential progression to Prx1+Sca1−cells, then Osx+Prx1−Sca1− osteoblast precursors, which eventually form mature α1(I)-collagen+ osteoblasts. |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 15 |
End Page | 17 |
language | 日本語 |
File Version | publisher |
Title Alternative | Introduction of Laboratory Animal Facilities in the Life Science Research Center, Gifu University |
---|---|
FullText URL | poalas_033_035_039.pdf |
Author | Nikami, Hideki| |
Abstract | The facilities of laboratory animal within the Division of Animal Experiments, Life Science Research Center, Gifu University was established in April 2005. In order to gain reliable data from animal experiments, it is vital that the subjects' environment be stable and well-controlled. In addition, the safety impact to humans and bioethical rules must be considered when conducting animal experiments. We provide both the facilities necessary for such experiments as well as comprehensive support in the form of experiment program planning and subject care and maintenance. |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 35 |
End Page | 39 |
language | 日本語 |
File Version | publisher |
Title Alternative | Introduction to the activities of the Regional Associations for Laboratory Animal Science |
---|---|
FullText URL | poalas_033_040_047.pdf |
Author | Okayama Association for Laboratory Animal Science| |
Abstract | わが国には現在11 の地区研究会があり、独自の活動が展開されています。本報では、各地区研究会の間での情報交換、交流などを意図して、平成28 年度の活動について北から順に紹介します。 なお、会長、事務局担当者及び講演者、話題提供者の方々のお名前は敬称を省略させていただきました。詳細な内容をご希望の方は各地区研究会の事務局にお問い合わせ下さい。 |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 40 |
End Page | 47 |
language | 日本語 |
File Version | publisher |
Title Alternative | 71th and 72th Meeting News, and the Secretary Meeting News |
---|---|
FullText URL | poalas_033_048_058.pdf |
Author | Okayama Association for Laboratory Animal Science| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 48 |
End Page | 59 |
language | 日本語 |
File Version | publisher |
Title Alternative | By-Low of membership fee and Notes of Contributors |
---|---|
FullText URL | poalas_033_059.pdf |
Author | Okayama Association for Laboratory Animal Science| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 59 |
End Page | 59 |
language | 日本語 |
File Version | publisher |
Title Alternative | Member Directory |
---|---|
Author | Okayama Association for Laboratory Animal Science| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 60 |
End Page | 64 |
language | 日本語 |
File Version | publisher |
Title Alternative | Organization and Rules of the Association |
---|---|
FullText URL | poalas_033_065_066.pdf |
Author | Okayama Association for Laboratory Animal Science| |
Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
Published Date | 2017-04 |
Volume | volume33 |
Start Page | 65 |
End Page | 66 |
language | 日本語 |
File Version | publisher |
FullText URL | jfl_067_contents.pdf |
---|---|
Author | 岡山大学文学部| |
Publication Title | Journal of the Faculty of Letters Okayama University |
Published Date | 2017-07-03 |
Volume | volume67 |
ISSN | 0285-4864 |
language | 日本語 |
File Version | publisher |
Title Alternative | Academic Contribution of the Teaching Staff of the Faculty of Letters, Okayama University (2016) |
---|---|
FullText URL | jfl_067_053_065.pdf |
Author | 岡山大学文学部| |
Publication Title | Journal of the Faculty of Letters Okayama University |
Published Date | 2017-07-03 |
Volume | volume67 |
Start Page | 53 |
End Page | 65 |
ISSN | 0285-4864 |
language | 日本語 |
File Version | publisher |
FullText URL | jfl_067_contents_eng.pdf |
---|---|
Author | 岡山大学文学部| |
Publication Title | Journal of the Faculty of Letters Okayama University |
Published Date | 2017-07-03 |
Volume | volume67 |
ISSN | 0285-4864 |
language | 英語 |
File Version | publisher |
FullText URL | oer_049_1_contents.pdf |
---|---|
Author | 岡山大学経済学会| |
Publication Title | Okayama Economic Review |
Published Date | 2017-07-03 |
Volume | volume49 |
Issue | issue1 |
ISSN | 2433-4146 |
language | 日本語 |
Copyright Holders | Copyright © 2017 岡山大学経済学会 |
File Version | publisher |
FullText URL | oer_049_1_colophon.pdf |
---|---|
Author | 岡山大学経済学会| |
Publication Title | Okayama Economic Review |
Published Date | 2017-07-03 |
Volume | volume49 |
Issue | issue1 |
ISSN | 2433-4146 |
language | 日本語 |
Copyright Holders | Copyright © 2017 岡山大学経済学会 |
File Version | publisher |
FullText URL | oer_049_1_contents_eng.pdf |
---|---|
Author | 岡山大学経済学会| |
Publication Title | Okayama Economic Review |
Published Date | 2017-07-03 |
Volume | volume49 |
Issue | issue1 |
ISSN | 2433-4146 |
language | 日本語 |
Copyright Holders | Copyright © 2017 岡山大学経済学会 |
File Version | publisher |
FullText URL | bgeou_165_contents.pdf |
---|---|
Author | 岡山大学大学院教育学研究科| |
Publication Title | Bulletin of Graduate School of Education, Okayama University |
Published Date | 2017-07-28 |
Volume | volume165 |
ISSN | 1883-2423 |
language | 日本語 |
File Version | publisher |