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ID 63035
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Meng, Xiang-Yu Department of Biochemistry and Molecular Biology, Mudanjiang Medical University
Yang, Guang Department of Pathology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine
Dong, Cheng-Ji Department of Hepatobiliary and Pancreas Surgery, The First Hospital of Jilin University
Zheng, Ru-Yi Medical Imaging Center, The Mine Hospital of Xu Zhou
Abstract
Gastric adenocarcinoma of the fundic gland is a rare, well-differentiated gastric cancer entity, and very few patients transition to poorly differentiated tubular adenocarcinoma during progression. Gastric adenocarcinoma of the fundic gland originates from the mucosa of the gastric fundic gland, usually without chronic gastritis or intestinal metaplasia. Histologically, the tumor cells are closely arranged to form anastomosing tubular glands, and more than 95% of tumor cells differentiate towards chief cells. Most gastric adenocarcinoma of the fundic gland cases are characterized by submucosal involvement, but the tumor volume is usually small, with lymphatic and vascular invasion rarely observed. Therefore, endoscopic submucosal dissection can be an ideal treatment, leading to a favorable prognosis, and recurrence and metastasis of the disease are uncommon.
Keywords
Gastric adenocarcinoma of the fundic gland
chief cells
histopathology
treatment
prognosis
Published Date
2021-12-14
Publication Title
Rare Tumors
Volume
volume13
Publisher
Sage Publications Ltd.
ISSN
2036-3605
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© The Author(s) 2021
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isVersionOf https://doi.org/10.1177/20363613211060171
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https://creativecommons.org/licenses/by-nc/4.0/