| ID | 17156 |
| Eprint ID | 17156
|
| FullText URL | |
| Title Alternative | Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 1. Measurement of urinary free light chains
|
| Author |
Namba, Yoshio
|
| Abstract | The concentration of urinary free light chains was measured in 61 patients with systemic lupus erythematosus (SLE) by single radial immunodiffusion. The concentration was significantly increased in these patients, and was associated with hypocomplementemia and a high level of antibody to DNA. It also correlated with the clinical disease activity of SLE. It is postulated that increased free light chain in the urine of SLE patients is derived mostly from increased synthesis of light chain rather than from increased breakdown of intact immunoglobulins or decrease of catabolism during renal insufficiency. The measurement of urinary free light chains may offer information for evaluating disease activity in SLE patients.
|
| Keywords | 全身性エリテマトーデス
遊離L鎖
|
| Published Date | 1980-12-30
|
| Publication Title |
岡山医学会雑誌
|
| Publication Title Alternative | Journal of Okayama Medical Association
|
| Volume | volume92
|
| Issue | issue11-12
|
| Publisher | 岡山医学会
|
| Publisher Alternative | Okayama Medical Association
|
| Start Page | 1107
|
| End Page | 1114
|
| ISSN | 0030-1558
|
| NCID | AN00032489
|
| Content Type |
Journal Article
|
| Official Url | https://www.jstage.jst.go.jp/article/joma1947/92/11-12/92_11-12_1107/_article/-char/ja/
|
| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
|
| language |
Japanese
|
| Copyright Holders | 岡山医学会
|
| File Version | publisher
|
| Refereed |
True
|
| Eprints Journal Name | joma
|
