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ID 42805
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Title Alternative
Influences of Organ Extracts as well as Serum of Blood Disease Patient on the Nucleic Acid Metabolism of a Rabbit 4th Report: Studies on The Nucleic Acid Metabolism due to Radioactive Isotope P(32)
Author
Namba, Tatsuji
Abstract
The once quantitatively estimated metabolism of nucleic acid in various organs has been put under examination, in view to its turnover rate, in terms of P(32), in its progressive form. 1) The ups and downs in nucleic acid amount does not always go parallel with the turnover rate. Therefore, when one considers the co relation between physiological or pathological funtion and nucleic acid, it is necessary to draw a strict distinctive line to tell whether it has certain concern with its quantitative transition, or with its turnover rate. 2) In case any serum has been injected except healthy person's the bone marrow nucleic acid, esp., the DNA wont to show a candid increase in its turnover rate; simultaneouly, if we consider it side by side with the extract administered case, we connot but imagine that the co-relation of bone-marrow nucleic acid metabolism and the number of peripheral blood carpusele should prove comparatively indirect one. 3) The liver DNA, though scarce compared to others, indicates a considerable rate in its turnover phase. From this, it may roughly be concluded that even if it be static nuclear DNA, maintains its metabolism which betrays the mistake in the theory that has termed it as stabilized and has no turnover faculty. 4) In the injection of serum, the spleen nucleic acid, above all, the turnover rate of DNA proves greater than bone-marrow; moreover, at this time, if one realizes the powerful growth of lymph follicles, it might be deemed suggestive of certain relation that exists between DNA turnover and splitting of cells.
Published Date
1955-01-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume67
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
221
End Page
230
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/67/1/67_1_221/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma