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ID 42805
フルテキストURL
67_221.pdf 687 KB
タイトル(別表記)
Influences of Organ Extracts as well as Serum of Blood Disease Patient on the Nucleic Acid Metabolism of a Rabbit 4th Report: Studies on The Nucleic Acid Metabolism due to Radioactive Isotope P(32)
著者
難波 達治 岡山大学医学部平木内科教室
抄録
The once quantitatively estimated metabolism of nucleic acid in various organs has been put under examination, in view to its turnover rate, in terms of P(32), in its progressive form. 1) The ups and downs in nucleic acid amount does not always go parallel with the turnover rate. Therefore, when one considers the co relation between physiological or pathological funtion and nucleic acid, it is necessary to draw a strict distinctive line to tell whether it has certain concern with its quantitative transition, or with its turnover rate. 2) In case any serum has been injected except healthy person's the bone marrow nucleic acid, esp., the DNA wont to show a candid increase in its turnover rate; simultaneouly, if we consider it side by side with the extract administered case, we connot but imagine that the co-relation of bone-marrow nucleic acid metabolism and the number of peripheral blood carpusele should prove comparatively indirect one. 3) The liver DNA, though scarce compared to others, indicates a considerable rate in its turnover phase. From this, it may roughly be concluded that even if it be static nuclear DNA, maintains its metabolism which betrays the mistake in the theory that has termed it as stabilized and has no turnover faculty. 4) In the injection of serum, the spleen nucleic acid, above all, the turnover rate of DNA proves greater than bone-marrow; moreover, at this time, if one realizes the powerful growth of lymph follicles, it might be deemed suggestive of certain relation that exists between DNA turnover and splitting of cells.
発行日
1955-01-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
67巻
1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
221
終了ページ
230
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/67/1/67_1_221/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma