検索結果 68 件
| JaLCDOI | 10.18926/AMO/56864 |
|---|---|
| フルテキストURL | 73_3_223.pdf |
| 著者 | Sugiu, Kazuhisa| Furumatsu, Takayuki| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Okazaki, Yuki| Hiranaka, Takaaki| Ozaki, Toshifumi| |
| 抄録 | Anterior cruciate ligament (ACL) reconstruction (ACLR) after ACL rupture improves the instability of the knee joint and decreases mechanical stress to the meniscus and articular cartilage. However, there are reports that post-traumatic osteoarthritis (PTOA) is observed over time following ACLR. In this study, we assessed changes in cartilage lesions by arthroscopic findings following anatomical double-bundle ACLR and at post-operative second-look arthroscopy about 14 months later. We retrospectively evaluated 37 knees in cases with patients <40 years of age who had undergone an anatomical double-bundle ACL reconstruction <1 year after ACL rupture injury from March 2012 to December 2016. Clinical results and arthroscopic cartilage/meniscal lesion were evaluated and compared between a cartilage lesion-detected group and intact-cartilage group. Surgery improved anteroposterior laxity and other clinical measures; however, cartilage lesions were detected at 11 sites during ACLR and at 54 sites at second-look arthroscopy. The periods from injury to second-look arthroscopy and from ACLR to second-look arthroscopy were significantly longer in the cartilage-lesion group (n=23) than in the intact-cartilage group (n=14). Conversely, 96% of meniscal damage observed during ACLR was cured at the time of second-look arthroscopy. Knee articular cartilage lesions after ACL rupture cannot be completely suppressed, even using the anatomical ACL reconstruction technique. This study suggested that articular cartilage lesions can progress to a level that can be confirmed arthroscopically at approximately 17 months after ACL injury. Therefore, in ACLR patients, the possibility of developing knee articular cartilage lesions and PTOA should be considered. |
| キーワード | anterior cruciate ligament reconstruction post-traumatic osteoarthritis meniscal lesion cartilage lesions second-look arthroscopy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-06 |
| 巻 | 73巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 223 |
| 終了ページ | 228 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31235969 |
| JaLCDOI | 10.18926/AMO/56452 |
|---|---|
| フルテキストURL | 73_1_1.pdf |
| 著者 | Morizane, Shin| |
| 抄録 | Excessive protease activity is a characteristic abnormality that affects the epidermal barrier in patients with atopic dermatitis (AD). Kallikrein-related peptidases (KLKs) are excessively expressed in AD lesions, and it is suggested that the abnormal action of KLKs is involved in the skin barrier dysfunction in AD. In other words, overexpressed KLKs disrupt the normal barrier function, and due to that breakdown, external substances that can become antigens of AD easily invade the epidermis, resulting in dermatitis, coupled with the induction of Th2 cytokines. Further investigations are required to elucidate the role of KLKs in AD; this knowledge could contribute to the design of new therapeutic and prophylactic drugs for AD. |
| キーワード | atopic dermatitis kallikrein-related peptidases epidermal barrier dysfunction |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-02 |
| 巻 | 73巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30820048 |
| タイトル（別表記） | Molecular targeted therapy in myeloma and lymphoma |
|---|---|
| フルテキストURL | 126_143.pdf |
| 著者 | 佐伯 恭昌| 前田 嘉信| 谷本 光音| |
| キーワード | 骨髄腫 リンパ腫 分子標的治療薬 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 143 |
| 終了ページ | 150 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.143 |
| NAID | 130004685266 |
| 著者 | 森実 真| 山崎 研志| 梶田 藍| 池田 佳寿子| Zhan, Maosheng| 青山 裕美| Richard L Gallo| 岩月 啓氏| |
|---|---|
| 発行日 | 2013-12-02 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 125巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Kawada, Kazuo| Lohar, Mohamed Khan| |
|---|---|
| 発行日 | 1989 |
| 出版物タイトル | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| 巻 | 19巻 |
| 号 | 4号 |
| 資料タイプ | 紀要論文 |
| 著者 | Lohar, Mohamad Khan| Kawada, Kazuo| |
|---|---|
| 発行日 | 1987 |
| 出版物タイトル | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| 巻 | 19巻 |
| 号 | 3号 |
| 資料タイプ | 紀要論文 |
| 著者 | Khan, Shahbaz Manzoor| Debnath, Chanchal| Pramanik, Amiya Kumar| Xiao, Lihua| Nozaki, Tomoyoshi| Ganguly, Sandipan| |
|---|---|
| 発行日 | 2010-07-15 |
| 出版物タイトル | Veterinary Parasitology |
| 巻 | 171巻 |
| 号 | 1-2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Khan, Shahbaz Manzoor| Debnath, Chanchal| Pramanik, Amiya Kumar| Xiao, Lihua| Nozaki, Tomoyoshi| Ganguly, Sandipan| |
|---|---|
| 発行日 | 2011-06-10 |
| 出版物タイトル | Veterinary Parasitology |
| 巻 | 178巻 |
| 号 | 3-4号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 万倉 三正| 野田 泰子| 森 昭胤| |
|---|---|
| 発行日 | 2012-04-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 124巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 小林 由佳| 山田 美佐| 藤井 裕美| 甲 由紀子| 魚谷 いづみ| 田本 真理子| 名田 正子| 村井 裕之| 角 英| 岩垣 博巳| 友田 純| 斎藤 信也| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/30947 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Khan, Rasel| Takahashi, Eizo| Nakura, Hironori| Ansaruzzaman, Mohammad| Banik, Sukalyani| Ramamurthy, Thandavarayan| Okamoto, Keinosuke| |
| 抄録 | Aeromonas are water-borne pathogens. They are halotolerant, which means that they can survive in environments whose salt content corresponds to that of seawater (3.0% NaCl). However, the presence of Aeromonas in seawater is extremely rare compared with that in river water. In this study, we tested the ability of Aeromonas sobria to produce toxins in river water and seawater. First, we cultured A. sobria on skim milk agar plates supplemented with either river water (SARW) or seawater (SASW). The bacteria grew on both plates. A clear zone around the bacteria was generated in SARW. However, such a zone was not observed in SASW, suggesting that proteases were not generated in SASW. Subsequently, we cultured A. sobria in a nutrient broth supplemented with either river water (NRW) or with seawater (NSW), and examined the protease activity of their culture supernatants. The protease activity of the culture supernatant from NSW was extremely low compared to that from NRW. The immunoblotting analysis showed that serine protease (ASP) was not produced by the culture in NSW. By contrast, aerolysin-like hemolysin was produced in all conditions examined in this study. This indicates that the salinity of water is deeply involved in the production of ASP by A. sobria. |
| キーワード | Aeromonas water toxin salinity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2008-12 |
| 巻 | 62巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 363 |
| 終了ページ | 371 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| Web of Science KeyUT | 000262025000002 |
| 著者 | Kandahary Rafiya Khan| |
|---|---|
| 発行日 | 2009-09-30 |
| 出版物タイトル | |
| 資料タイプ | 学位論文 |
| 著者 | RASEL KHAN| |
|---|---|
| 発行日 | 2008-09-30 |
| 資料タイプ | 学位論文 |
| 著者 | 角南 宏二| |
|---|---|
| 発行日 | 1992-12 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 104巻 |
| 号 | 11-12号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 渡辺 和彦| 岩垣 博巳| 淵本 定儀| 椎木 滋雄| 松原 長秀| 赤在 義浩| 渡辺 哲也| 須崎 紀一| 浜田 史洋| 合地 明| 日伝 晶夫| 折田 薫三| |
|---|---|
| 発行日 | 1991-08 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 103巻 |
| 号 | 7-8号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 大林 直嗣| |
|---|---|
| 発行日 | 1993-08 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 105巻 |
| 号 | 7-8号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 石川 雅巳| |
|---|---|
| 発行日 | 1996-02-29 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 108巻 |
| 号 | 1-2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 荻野 景規| |
|---|---|
| 発行日 | 2007-01-04 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 118巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/fest/12835 |
|---|---|
| フルテキストURL | 13_103_109.pdf |
| 著者 | Khan Md. Harunor Rashid| Kabir Syed Monzur| Bhuiyan Md. Mukaddas Ali| Blume Hans-Peter| |
| 抄録 | A simulation study was conducted to evaluate the effects of basic slag (BS10 and BS20: basic slag 10 and 20 t ha-1), aggregate size (A20 and A30: aggregate sizes of soil, less than 20 and 20-30 mm) and groundwater depth (Gw0: no influence of groundwater and Gw50: groundwater beneath 50 cm of the soil surface) as physico-chemical amendments in two pre-leached (leached for a week through tap water to remove excessive acidity and salinity from the soil before transplantation) acid sulfate soils of Badarkhali (Salidic Sulfaquept) and Cheringa (Typic Sulfic Halaquept) series in relation to the production of Chilli (Capsicum annum L.). Maximum growth and yield of chilli were recorded by the treatment combining A30Gw50BS20 in both the Cheringa (green chilli weight: 4.82 t ha-1) and Badarkhali (4.51 t ha-1) soils. The application of basic slag (BS20) was found to be the most effective among the individual treatments, followed by the BS10 > A30 > Gw50 treatments. The application of BS20 increased the yield in combination with the Gw0 treatment by 40% for A20, while by 107% for A30 in the Badarkhali soil. On the other hand, in the case of Gw50, these increments were 49 and 141% for A20 and A30, respectively. The application of BS at the highest rate (BS20) to the Cheringa soil was more effective compared with the A20 and A30 treatments in the Badarkhali soil. The same rate of BS20 in combination with the Gw50 treatment increased the yield by 59 to 147% in the Cheringa soil compared with 49 to 141% in the Badarkhali soil. Almost similar and significant (p≤0.05) effects were observed for the other growth parameters of chilli cultivated in both soil series. |
| キーワード | aggregate size basic slag groundwater growth and yield of chilli physico-chemical amendments of acid sulfate soils |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2008-03 |
| 巻 | 13巻 |
| 号 | 1号 |
| 開始ページ | 103 |
| 終了ページ | 109 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002304787 |
| JaLCDOI | 10.18926/fest/12834 |
|---|---|
| フルテキストURL | 13_097_101.pdf |
| 著者 | Khan Md. Harunor Rashid| Md. Mohiuddin| M. Rahman| |
| 抄録 | Non-symbiotic diazotrophic systems for biological nitrogen fixation (BNF) in agriculture are most promising but the possibility for the extension of nitrogen fixation by rice is still speculative. Accordingly, the present study was conducted for the Enumeration, isolation and identification of nitrogen fixing bacterial strains at seedling stage (30 days after seed sowing) in rhizosphere of rice (BR 10, Oryza sativa L.) grown in Non-Calcareous Grey Flood Plain soil of Bangladesh. The soil is classified as ‘Inceptisol’ order and ‘Aquept’ suborder. It was identified as ‘Dhamrai series’, had ‘silt’ texture, pH 7.1 and 5.5 C/N ratio. The present results of the microbial tests on the rice rhizosphere soil evinced that out of 263 isolates, only 91 were branded as nitrogen fixing organisms per gram of soil, which was about 34.6 % of the total isolates. As per selection criteria, four individual strains were considered for identification. Biochemical tests were conducted for proper identification and the selected strains were identified as Enterobacter spp., Klebsiella spp., Bacillus spp. and Azospirllum spp. |
| キーワード | Azospirllum spp. Bacillus spp. diazotrophs Enterobacter Spp. Klebsiella spp. and Oryza sativa. |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2008-03 |
| 巻 | 13巻 |
| 号 | 1号 |
| 開始ページ | 97 |
| 終了ページ | 101 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002304761 |