検索結果 - 岡山大学学術成果リポジトリ

Utility of Comprehensive Genomic Profiling for Precise Diagnosis of Pediatric-Type Diffuse High-Grade Glioma

JaLCDOI	10.18926/AMO/65502
フルテキストURL	77_3_323.pdf
著者	Makino, Keigo\| Otani, Yoshihiro\| Fujii, Kentaro\| Ishida, Joji\| Hirano, Shuichiro \| Suruga, Yasuki\| Washio, Kana\| Nishida, Kenji\| Yanai, Hiroyuki\| Tomida, Shuta\| Ennishi, Daisuke\| Date, Isao\|
抄録	In the current World Health Organization classification of central nervous system tumors, comprehensive genetic and epigenetic analyses are considered essential for precise diagnosis. A 14-year-old male patient who presented with a cerebellar tumor was initially diagnosed with glioblastoma and treated with radiation and concomitant temozolomide chemotherapy after resection. During maintenance temozolomide therapy, a new contrast-enhanced lesion developed in the bottom of the cavity formed by the resection. A second surgery was performed, but the histological findings in specimens from the second surgery were different from those of the first surgery. Although genome-wide DNA methylation profiling was conducted using frozen tissue for a precise diagnosis, the proportion of tumor cells was insufficient and only normal cerebellum was observed. We then performed comprehensive genetic analysis using formalin-fixed paraffin-embedded sections, which revealed MYCN amplification without alteration of IDH1, IDH2, or Histone H3. Finally, the patient was diagnosed with pediatric-type diffuse high-grade glioma, H3-wildtype and IDH-wildtype. In conclusion, comprehensive genetic and epigenetic analysis should be considered in pediatric brain tumor cases.
キーワード	comprehensive genomic profiling pediatric brain tumor genome-wide DNA methylation MYCN
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-06
巻	77巻
号	3号
出版者	Okayama University Medical School
開始ページ	323
終了ページ	330
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37357634
Web of Science KeyUT	001025850000001

NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism

フルテキストURL	fulltext.pdf
著者	Okada, Nobuhiro\| Ueki, Chihiro\| Shimazaki, Masahiro\| Tsujimoto, Goki\| Kohno, Susumu\| Muranaka, Hayato\| Yoshikawa, Kiyotsugu\| Takahashi, Chiaki\|
備考	The version of record of this article, first published in Communications Biology, is available online at Publisher’s website: http://dx.doi.org/10.1038/s42003-023-04987-9\|
発行日	2023-06-02
出版物タイトル	Communications Biology
巻	6巻
号	1号
出版者	nature portfolio
開始ページ	596
ISSN	2399-3642
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37268670
DOI	10.1038/s42003-023-04987-9
Web of Science KeyUT	000999915600001
関連URL	isVersionOf https://doi.org/10.1038/s42003-023-04987-9

岡山県吉備中央町賀陽周辺の古第三系～新第三系の地質と吉備高原面のゆるやかな曲隆

JaLCDOI	10.18926/ESR/65479
タイトル（別表記）	Geology of the Paleogene to Neogene successions and gentle upwarping of the Kibi Plateau Surface, surrounding area of Kibichuou Town, Okayama Prefecture, Southwest Japan
フルテキストURL	esr_029_001_027.pdf
著者	田中元\| 鈴木茂之\|
抄録	The Paleogene to Neogene successions which are composed of the Paleogene Kayo Formation, the late Oligocene to earliest Miocene Yagane Formation and the middle Miocene Ukan Formation are sporadically distributed in the Kibi Plateau region, surrounding area of Kibichuou Town, Okayama Prefecture, Southwest Japan. The gravel of the Kayo Formation occupied paleo-valley of Pre-Paleogene basement. The Yagane and Ukan formations unconformably overlay Pre-Paleogene rocks and occupy the gentle valley on the Kibi Surface as valley fill deposits. The fluvial of the Kayo Formation is mainly composed of conglomerate with minor amount of sandstone and mudstone. The fluvial Yagane Formation is mainly composed of conglomerate and associated with sandstone, mudstone and coal beds. The marine Ukan Formation is subdivided into 3 members, the Yamagata Muddy sandstone Member (YMM), the Shimoyokomi Sandstone Member (SSM) and the Tsuneyama Mudstone Member (TMM) in ascending order. The YMM is characterized by the bio-disturbed very poorly sorted muddy sandstone with frequent burrows, which indicate tidal flat deposits. The SSM is mainly composed of parallel bedded well-sorted sandstone with occasional burrows, which suggest near shore deposits. The TMM is composed of homogeneous clay rich mudstone, which implies off shore deposits. The boundary between the SSM and TMM (the contact of the sandstone and mudstone) is distinctive and correlative throughout the study area. The boundary is considered to be formed under similar water depth. The variations of the boundary height indicate a later ground movement. From the north to the south in about 25km distance, the height of the boundary changes 260m (in Ukan), 300m (in Takeshou), 360m (in Kibikogentoshi) and 260m (in Nichiouji). It indicates that a very gentle upwarping of the Kibi Plateau Surface was formed after the deposition of the Miocene.
キーワード	Kibi Plateau Surface Upwarping Miocene Ukan Formation
出版物タイトル	Okayama University Earth Science Report
発行日	2023-03-31
巻	29巻
号	1号
開始ページ	1
終了ページ	27
ISSN	1340-7414
言語	日本語
著作権者	© 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン	publisher

Semantic Bimodal Presentation Differentially Slows Working Memory Retrieval

フルテキストURL	fulltext.pdf
著者	Cheng, Jia\| Li, Jingjing\| Wang, Aijun\| Zhang, Ming\|
キーワード	multisensory congruency bimodal n-back concrete words abstract words working memory modal representations
発行日	2023-05-17
出版物タイトル	Brain Sciences
巻	13巻
号	5号
出版者	MDPI
開始ページ	811
ISSN	2076-3425
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	37239283
DOI	10.3390/brainsci13050811
Web of Science KeyUT	000995597000001
関連URL	isVersionOf https://doi.org/10.3390/brainsci13050811

Idiopathic Plasmacytic Lymphadenopathy Forms an Independent Subtype of Idiopathic Multicentric Castleman Disease

フルテキストURL	K0006870‗fulltext.pdf K0006870_summary.pdf K0006870_abstract_review.pdf
著者	錦織亜沙美\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6870号
学位授与年月日	2023-03-24
学位・専攻分野	博士（保健学）
授与大学	岡山大学
言語	英語
著作権者	© 2022 by the authors.

Do Complementary and Alternative Medicine Users Also Use Conventional Medicine? A Repeated Cross-Sectional Study in Japan from 1995 to 2013

フルテキストURL	K0006802_abstract_review.pdf K0006802_fulltext.pdf K0006802_summary.pdf
著者	松木宣嘉 \|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6802号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

Suramin prevents the development of diabetic kidney disease by inhibiting NLRP3 inflammasome activation in KK-Ay mice

フルテキストURL	K0006760_abstract_review.pdf K0006760_fulltext.pdf K0006760_other1.pdf K0006760_other2.pdf K0006760_other3.pdf K0006760_summary.pdf
著者	小田香織\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6760号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2022 The Authors.

Correlation between renal ablation zone in contrast-enhanced CT and non-enhanced MRI during the early period following percutaneous cryoablation

フルテキストURL	K0006758_abstract_review.pdf K0006758_fulltext.pdf K0006758_summary.pdf
著者	馬越紀行\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6758号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© The Author(s) 2022

Differences in extracellular fluid volume between acute heart failure patients with and without high systolic blood pressure

フルテキストURL	K0006754_abstract_review.pdf K0006754_fulltext.pdf K0006754_summary.pdf
著者	難波悠介\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6754号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2022 The Authors.

Particle and Heavy Ion Transport Code System‐Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy

フルテキストURL	fulltext20230530-01.pdf
著者	Shigehira, Takafumi\| Hanafusa, Tadashi\| Igawa, Kazuyo\| Kasai, Tomonari\| Furuya, Shuichi\| Nishimori, Hisakazu\| Maeda, Yoshinobu\| Michiue, Hiroyuki\| Fujimura, Atsushi\|
キーワード	boron agents boron neutron capture therapy simulation study
備考	This is the peer reviewed version of the following article: T. Shigehira, T. Hanafusa, K. Igawa, T. Kasai, S. Furuya, H. Nishimori, Y. Maeda, H. Michiue, A. Fujimura, Particle and Heavy Ion Transport Code System-Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy. Adv. Theory Simul. 2023, 6, 2300163. https://doi.org/10.1002/adts.202300163, which has been published in final form at https://doi.org/10.1002/adts.202300163. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\| This fulltext file will be available in Apr. 2024.\|
発行日	2023-04-28
出版物タイトル	Advanced Theory and Simulations
巻	6巻
号	7号
出版者	Wiley
開始ページ	2300163
ISSN	2513-0390
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Wiley-VCH GmbH
論文のバージョン	author
DOI	10.1002/adts.202300163
Web of Science KeyUT	000978086700001
関連URL	isVersionOf https://doi.org/10.1002/adts.202300163

An investigation of the internal morphology of asbestos ferruginous bodies: constraining their role in the onset of malignant mesothelioma

フルテキストURL	fulltext.pdf
著者	Avramescu, Maya-Liliana\| Potiszil, Christian\| Kunihiro, Tak\| Okabe, Kazunori\| Nakamura, Eizo\|
キーワード	Asbestos fibre Asbestos body Malignant mesothelioma Asbestos body internal morphology
発行日	2023-05-08
出版物タイトル	Particle and Fibre Toxicology
巻	20巻
号	1号
出版者	BMC
開始ページ	19
ISSN	1743-8977
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37150820
DOI	10.1186/s12989-023-00522-0
Web of Science KeyUT	000983293400001
関連URL	isVersionOf https://doi.org/10.1186/s12989-023-00522-0

Flotation kinetics of aluminum powders derived from waste crystalline silicon solar cells and its comparison between batch, continuous and column flotation practices

フルテキストURL	fulltext20230526-02.pdf
著者	Kato, Yoshiei\| Harada, Sho\| Nishimura, Noriko\| Uddin, Md. Azhar\| Uchida, Yu-ichi\|
キーワード	Flotation Recovery Waste solar cell Column flotation Cell-to-cell flotation
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10163-022-01564-w\| This fulltext file will be available in Dec. 2023.\|
発行日	2022-12-10
出版物タイトル	Journal of Material Cycles and Waste Management
巻	25巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	826
終了ページ	834
ISSN	1438-4957
NCID	AA11589627
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Springer Japan KK, part of Springer Nature 2022
論文のバージョン	author
DOI	10.1007/s10163-022-01564-w
Web of Science KeyUT	000897383600002
関連URL	isVersionOf https://doi.org/10.1007/s10163-022-01564-w

The dataset of de novo assembly and inferred functional annotation of the transcriptome of Heterosigma akashiwo, a bloom-forming, cosmopolitan raphidophyte

フルテキストURL	fulltext.pdf
著者	Sato, Masanao\| Seki, Masahide\| Suzuki, Yutaka\| Ueki, Shoko\|
キーワード	Harmful alga Nuclear gene Gene prediction Gene ontology Stramenopile Heterokont
発行日	2023-06
出版物タイトル	Data in Brief
巻	48巻
出版者	Elsevier
開始ページ	109071
ISSN	2352-3409
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Author(s).
論文のバージョン	publisher
PubMed ID	37066092
DOI	10.1016/j.dib.2023.109071
Web of Science KeyUT	000967777500001
関連URL	isVersionOf https://doi.org/10.1016/j.dib.2023.109071

Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis

フルテキストURL	fulltext.pdf
著者	Iwasa, Mitsusada\| Takeda, Shuichi\| Narita, Akihiro\| Maeda, Yuichiro\| Oda, Toshiro\|
キーワード	MD simulation actin water dynamics ATP hydrolysis X-ray structure baculovirus expression
発行日	2023-03-16
出版物タイトル	Frontiers in Cell and Developmental Biology
巻	11巻
出版者	Frontiers Media
開始ページ	1105460
ISSN	2296-634X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Iwasa, Takeda, Narita, Maéda and Oda.
論文のバージョン	publisher
PubMed ID	37009486
DOI	10.3389/fcell.2023.1105460
Web of Science KeyUT	000962129300001
関連URL	isVersionOf https://doi.org/10.3389/fcell.2023.1105460

Evaluation of the association of birth order and group childcare attendance with Kawasaki disease using data from a nationwide longitudinal survey

フルテキストURL	fulltext.pdf
著者	Namba, Takahiro\| Takeuchi, Akihito\| Matsumoto, Naomi\| Tsuge, Mitsuru\| Yashiro, Masato\| Tsukahara, Hirokazu\| Yorifuji, Takashi\|
キーワード	Kawasaki disease (KD) birth order group childcare infectious diseases vasculitis
発行日	2023-03-28
出版物タイトル	Frontiers in Pediatrics
巻	11巻
出版者	Frontiers Media
開始ページ	1127053
ISSN	2296-2360
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Namba, Takeuchi, Matsumoto, Tsuge, Yashiro, Tsukahara and Yorifuji.
論文のバージョン	publisher
PubMed ID	37056943
DOI	10.3389/fped.2023.1127053
Web of Science KeyUT	000965495400001
関連URL	isVersionOf https://doi.org/10.3389/fped.2023.1127053

Urinary Retention Suggesting Aseptic Meningitis: Meningitis-Retention Syndrome Without Physical Signs of Meningeal Irritation

JaLCDOI	10.18926/AMO/65150
フルテキストURL	77_2_199.pdf
著者	Nagano, Tomohiro\| Hosokawa, Shinobu\| Miyahara, Hideaki\| Yamada, Kotaro\| Umeno, Takayuki\| Kano, Hirohisa\| Kayatani, Hiroe\| Sakugawa, Makoto\| Takehisa, Yasushi\| Takenaka, Tadasu\| Takeuchi, Makoto\| Bessho, Akihiro\|
抄録	Meningitis-retention syndrome (MRS) is the combination of aseptic meningitis and acute urinary retention that occurs in the absence of other neurological diseases. The cause(s) of MRS remain unclear. A 57-year-old Japanese woman was referred to our hospital for the evaluation of persistent fever and headache. The fever’s cause was initially unclear, but the presence of urinary retention raised concern about possible aseptic meningitis despite no physical indications of meningeal irritation. Only typical cases of MRS have been reported thus far to our knowledge, and it is important that clinicians are aware of MRS when it presents in this atypical form.
キーワード	meningitis-retention syndrome aseptic meningitis acute urinary retention
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-04
巻	77巻
号	2号
出版者	Okayama University Medical School
開始ページ	199
終了ページ	201
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37094958
Web of Science KeyUT	000982503800010

Personalized Preclinical Training in Dental Ergonomics and Endodontics in Undergraduate Dentistry Students (Pilot Study)

JaLCDOI	10.18926/AMO/65144
フルテキストURL	77_2_147.pdf
著者	Arias, Zulema\| Haines, Stephanie\| Yamamoto, Tadashi\| Hatanaka, Kazu\| Yamashiro, Keisuke\| Sonoi, Norihiro\| Takashiba, Shogo\|
抄録	The curriculum at the Department of Pathophysiology in the Periodontal Sciences program at Okayama University includes normative preclinical training (NPT) using phantoms. NPT is given to the whole class of 5 th year students divided in groups of 8 students/instructor. In 2019, an innovative personalized preclinical training (PPT) pilot study was implemented for this group of students whereby two students, each with their own dental unit, were coached by one instructor. The main topics covered were dental ergonomics and endodontics. We aimed to evaluate the effectiveness of PPT in dental ergonomics and endodontics toward increasing the knowledge and future clinical skills of students who had already undergone NPT. A test on endodontics was taken before and after PPT. A questionnaire was completed to assess their perception of improvement regarding the above-mentioned topics. Test scores and questionnaire results both showed that the students’ level of knowledge and awareness of future clinical skills was significantly higher after PPT. This pilot study demonstrated that PPT increased the students’ knowledge and future clinical skills. As preclinical training forms the foundation for clinical practice, investment in future research regarding this personalized approach is likely to enhance students’ understanding and clinical performance.
キーワード	preclinical personalized education dental ergonomics endodontics clinical skills improvement undergraduate students
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-04
巻	77巻
号	2号
出版者	Okayama University Medical School
開始ページ	147
終了ページ	159
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37094952
Web of Science KeyUT	000982503800004

Pioneer Use of Antimalarial Transdermal Combination Therapy in Rodent Malaria Model

フルテキストURL	fulltext.pdf
著者	Aly, Nagwa S. M.\| Matsumori, Hiroaki\| Dinh, Thi Quyen\| Sato, Akira\| Miyoshi, Shin-Ichi\| Chang, Kyung-Soo\| Yu, Hak Sun\| Cao, Duc Tuan\| Kim, Hye-Sook\|
キーワード	transdermal N-89 mefloquine pyrimethamine antimalarials combination in vivo
発行日	2023-03-01
出版物タイトル	Pathogens
巻	12巻
号	3号
出版者	MDPI
開始ページ	398
ISSN	2076-0817
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	36986320
DOI	10.3390/pathogens12030398
Web of Science KeyUT	000958932800001
関連URL	isVersionOf https://doi.org/10.3390/pathogens12030398

「することもありうる」を述語にする文のデオンティックな側面

JaLCDOI	10.18926/65121
タイトル（別表記）	Deontic Aspects of Japanese Sentences with Predicate Form Suru koto mo ariuru
フルテキストURL	hss_055_001.pdf
著者	宮崎和人\|
出版物タイトル	岡山大学大学院社会文化科学研究科紀要
発行日	2023-03-27
巻	55巻
開始ページ	1
終了ページ	10
ISSN	1881-1671
言語	日本語
著作権者	Copyright (c) 2023 岡山大学大学院社会文化科学研究科
論文のバージョン	publisher

Novel Artificial Scaffold for Bone Marrow Regeneration: Honeycomb Tricalcium Phosphate

フルテキストURL	fulltext.pdf
著者	Inada, Yasunori\| Takabatake, Kiyofumi\| Tsujigiwa, Hidetsugu\| Nakano, Keisuke\| Shan, Qiusheng\| Piao, Tianyan\| Chang, Anqi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\|
キーワード	honeycomb TCP bone marrow formation scaffold hematopoietic stem cell (HSC) N-cadherin-positive spindle-shaped osteoblasts (SNO cells)
発行日	2023-02-07
出版物タイトル	Materials
巻	16巻
号	4号
出版者	MDPI
開始ページ	1393
ISSN	1996-1944
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	36837023
DOI	10.3390/ma16041393
Web of Science KeyUT	000953562700001
関連URL	isVersionOf https://doi.org/10.3390/ma16041393