検索結果 - 岡山大学学術成果リポジトリ

Viral Sequences Are Repurposed for Controlling Antiviral Responses as Non-Retroviral Endogenous Viral Elements

JaLCDOI	10.18926/AMO/64025
フルテキストURL	76_5_503.pdf
著者	Ogawa, Hirohito\| Honda, Tomoyuki\|
抄録	Eukaryotic genomes contain numerous copies of endogenous viral elements (EVEs), most of which are considered endogenous retrovirus (ERV) sequences. Over the past decade, non-retroviral endogenous viral elements (nrEVEs) derived from ancient RNA viruses have been discovered. Several functions have been proposed for these elements, including antiviral defense. This review summarizes the current understanding of nrEVEs derived from RNA viruses, particularly endogenous bornavirus-like elements (EBLs) and endogenous filovirus-like elements (EFLs). EBLs are one of the most extensively studied nrEVEs. The EBL derived from bornavirus nucleoprotein (EBLN) is thought to function as a non-coding RNA or protein that regulates host gene expression or inhibits virus propagation. Ebolavirus and marburgvirus, which are filoviruses, induce severe hemorrhagic fever in humans and nonhuman primates. Although the ecology of filoviruses remains unclear, bats are believed to be potential reservoirs. Based on the knowledge from EBLs, it is postulated that EFLs in the bat genome help to maintain the balance between filovirus infection and the bat’s defense system, which may partially explain why bats act as potential reservoirs. Further research into the functions of nrEVEs could reveal novel antiviral systems and inspire novel antiviral approaches.
キーワード	EVE nrEVE bornavirus filovirus antiviral
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2022-10
巻	76巻
号	5号
出版者	Okayama University Medical School
開始ページ	503
終了ページ	510
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36352796
Web of Science KeyUT	000884907100002

Current Insights into Mesenchymal Signatures in Glioblastoma

JaLCDOI	10.18926/AMO/64024
フルテキストURL	76_5_489.pdf
著者	Matsumoto, Yuji\| Ichikawa, Tomotsugu\| Kurozumi, Kazuhiko\| Date, Isao\|
抄録	Glioblastoma (GBM) is a fatal primary malignant brain tumor in adults. Despite decades of research, the prognosis for GBM patients is still disappointing. One major reason for the intense therapeutic resistance of GBM is inter- and intra-tumor heterogeneity. GBM-intrinsic transcriptional profiling has suggested the presence of at least three subtypes of GBM: the proneural, classic, and mesenchymal subtypes. The mesenchymal subtype is the most aggressive, and patients with the mesenchymal subtype of primary and recurrent tumors tend to have a worse prognosis compared with patients with the other subtypes. Furthermore, GBM can shift from other subtypes to the mesenchymal subtype over the course of disease progression or recurrence. This phenotypic transition is driven by diverse tumor-intrinsic molecular mechanisms or microenvironmental factors. Thus, better understanding of the plastic nature of mesenchymal transition in GBM is pivotal to developing new therapeutic strategies. In this review, we provide a comprehensive overview of the current understanding of the elements involved in the mesenchymal transition of GBM and discuss future perspectives.
キーワード	glioma glioblastoma mesenchymal subtype mesenchymal transition heterogeneity
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2022-10
巻	76巻
号	5号
出版者	Okayama University Medical School
開始ページ	489
終了ページ	502
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36352795
Web of Science KeyUT	000884907100001

Deep learning model for analyzing the relationship between mandibular third molar and inferior alveolar nerve in panoramic radiography

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Tanaka, Futa\| Hara, Takeshi\| Yoshii, Kazumasa\| Yamashita, Katsusuke\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
発行日	2022-10-08
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	16925
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	36209283
DOI	10.1038/s41598-022-21408-9
Web of Science KeyUT	000865228800021
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-21408-9

Prevalence of medical factors related to aging among older car drivers: a multicenter, cross-sectional, descriptive study

フルテキストURL	fulltext.pdf
著者	Hagiya, Hideharu\| Takase, Ryosuke\| Honda, Hiroyuki\| Nakano, Yasuhiro\| Otsuka, Yuki\| Kataoka, Hitomi\| Uno, Mika\| Ueda, Keigo\| Takahashi, Misa\| Ogawa, Hiroko\| Hanayama, Yoshihisa\| Otsuka, Fumio\|
キーワード	Traffic safety Older people Aging Motor vehicle accidents Frailty Dementia Polypharmacy Sarcopenia
発行日	2022-10-11
出版物タイトル	BMC Geriatrics
巻	22巻
号	1号
出版者	BMC
開始ページ	792
ISSN	1471-2318
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	36221051
DOI	10.1186/s12877-022-03490-w
Web of Science KeyUT	000866114200002
関連URL	isVersionOf https://doi.org/10.1186/s12877-022-03490-w

Cnm of Streptococcus mutans is important for cell surface structure and membrane permeability

フルテキストURL	fulltext.pdf
著者	Naka, Shuhei\| Matsuoka, Daiki\| Goto, Kana\| Misaki, Taro\| Nagasawa, Yasuyuki\| Ito, Seigo\| Nomura, Ryota\| Nakano, Kazuhiko\| Matsumoto-Nakano, Michiyo\|
キーワード	Streptococcus mutans collagen-binding protein membrane permeability cell structure RNA-seq
発行日	2022-09-13
出版物タイトル	Frontiers In Cellular And Infection Microbiology
巻	12巻
出版者	Frontiers Media S.A.
開始ページ	994014
ISSN	2235-2988
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Naka, Matsuoka, Goto, Misaki, Nagasawa, Ito, Nomura, Nakano and Matsumoto-Nakano.
論文のバージョン	publisher
PubMed ID	36176579
DOI	10.3389/fcimb.2022.994014
Web of Science KeyUT	000861324100001
関連URL	isVersionOf https://doi.org/10.3389/fcimb.2022.994014

Genomic Profiling of a Case of Glioneuronal Tumor with Neuropil-like Islands

JaLCDOI	10.18926/AMO/63907
フルテキストURL	76_4_473.pdf
著者	Tsuboi, Nobushige\| Ishida, Joji\| Shimazu, Yosuke\| Edaki, Hisanori\| Uneda, Atsuhito\| Otani, Yoshihiro\| Fujii, Kentaro\| Kurozumi, Kazuhiko\| Ennishi, Daisuke\| Yanai, Hiroyuki\| Date, Isao\|
抄録	Glioneuronal tumor with neuropil-like islands (GNTNI) is a very rare subtype of glioneuronal tumor. We present a case of a 62-year-old man with GNTNI. Two adjacent lesions in the left parietal lobe were removed by left parietal craniotomy. The histological findings were glial cell proliferation and scattered rosettes consisting of synaptophysin-positive and NeuN-positive cells, leading to the diagnosis of GNTNI. Target sequencing revealed a genetic alteration similar to glioblastoma, IDH-wild type, which suggested adjuvant therapies. There are few previous reports on the treatment of this disease, and the patient should be followed carefully.
キーワード	glioneuronal tumor with neuropil-like islands genomic profiling
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-08
巻	76巻
号	4号
出版者	Okayama University Medical School
開始ページ	473
終了ページ	477
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36123163

Mutual Effects of Orexin and Bone Morphogenetic Proteins on Gonadotropin Expression by Mouse Gonadotrope Cells

フルテキストURL	fulltext.pdf
著者	Soejima, Yoshiaki\| Iwata, Nahoko\| Nakayama, Nanako\| Hirata, Shinichi\| Nakano, Yasuhiro\| Yamamoto, Koichiro\| Suyama, Atsuhito\| Oguni, Kohei\| Nada, Takahiro\| Fujisawa, Satoshi\| Otsuka, Fumio\|
キーワード	bone morphogenetic protein (BMP) clock gonadotropin orexin pituitary
発行日	2022-08-29
出版物タイトル	International Journal Of Molecular Sciences
巻	23巻
号	17号
出版者	MDPI
開始ページ	9782
ISSN	1422-0067
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	36077179
DOI	10.3390/ijms23179782
Web of Science KeyUT	000851102000001
関連URL	isVersionOf https://doi.org/10.3390/ijms23179782

Candida dubliniensis fungemia in a patient with severe COVID-19: A case report

フルテキストURL	fulltext20220906-1.pdf
著者	Kakehi, Ayaka\| Hagiya, Hideharu\| Iio, Koji\| Nakano, Yasuhiro\| Ihoriya, Hiromi\| Taira, Yuki\| Nakamoto, Kenta\| Hasegawa, Kou\| Higashikage, Akihito\| Otsuka, Fumio\|
キーワード	Candida dubliniensis Candidemia COVID-19 Sequencing analysis
備考	© 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jiac.2022.07.007] . \|
発行日	2022-10
出版物タイトル	Journal of Infection and Chemotherapy
巻	28巻
号	10号
出版者	Elsevier BV
開始ページ	1433
終了ページ	1435
ISSN	1341-321X
NCID	AA11057978
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases.
論文のバージョン	author
PubMed ID	35863730
DOI	10.1016/j.jiac.2022.07.007
Web of Science KeyUT	000843880400016
関連URL	isVersionOf https://doi.org/10.1016/j.jiac.2022.07.007

Japanese case of Charcot–Marie–Tooth disease type 2Z with severe retinitis pigmentosa

フルテキストURL	fulltext20220830-4.pdf CMT2Z Figure NCN revise.tif CMT2Z Table NCN revise.tif
著者	Nomura, Emi\| Tadokoro, Koh\| Sasaki, Ryo\| Nakata, Yumi\| Nakano, Yumiko\| Yunoki, Taijun\| Takemoto, Mami\| Morihara, Ryuta\| Ando, Masahiro\| Takashima, Hiroshi\| Yamashita, Toru\|
キーワード	Charcot-Marie-Tooth disease type 2Z MORC2 retinitis pigmentosa
備考	This is the peer reviewed version of the following article: [Nomura, E, Tadokoro, K, Sasaki, R, et al. Japanese case of Charcot–Marie–Tooth disease type 2Z with severe retinitis pigmentosa. Neurol Clin Neurosci. 2022; 10: 266-268. doi: 10.1111/ncn3.12660], which has been published in final form at [https://doi.org/10.1111/ncn3.12660]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
発行日	2022-08-15
出版物タイトル	Neurology and Clinical Neuroscience
巻	10巻
号	5号
出版者	Wiley
開始ページ	266
終了ページ	268
ISSN	2049-4173
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd.
論文のバージョン	author
DOI	10.1111/ncn3.12660
Web of Science KeyUT	000843400700001
関連URL	isVersionOf https://doi.org/10.1111/ncn3.12660

Innovative clinical pathway shortened the length of hospital stay and prevented readmission in patients with acute decompensated heart failure

フルテキストURL	fulltext20220830-3.pdf
著者	Amioka, Naofumi\| Takaishi, Atsushi\| Nakamura, Kazufumi\| Endo, Toyohiro\| Iida, Toshihiro\| Yamaji, Tatsuya\| Mori, Hisatoshi\| Kishinoue, Takao\| Yasuhara, Kentaro\| Matsuo, Naoaki\| Tanimoto, Masafumi\| Nakano, Yukari\| Onishi, Nobuhiko\| Ueeda, Masayuki\| Ito, Hiroshi\|
キーワード	Clinical pathway Acute decompensated heart failure Tolvaptan Cardiac rehabilitation Prognosis
備考	© 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jjcc.2022.03.014] . \|
発行日	2022-09
出版物タイトル	Journal of Cardiology
巻	80巻
号	3号
出版者	Elsevier BV
開始ページ	232
終了ページ	239
ISSN	0914-5087
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Elsevier B.V.
論文のバージョン	author
PubMed ID	35428556
DOI	10.1016/j.jjcc.2022.03.014
Web of Science KeyUT	000838175500008
関連URL	isVersionOf https://doi.org/10.1016/j.jjcc.2022.03.014

Effective deep learning for oral exfoliative cytology classification

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Tanaka, Futa\| Nakano, Keisuke\| Hara, Takeshi\| Yoshii, Kazumasa\| Yamashita, Katsusuke\| Ono, Sawako\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
発行日	2022-08-02
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	13281
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35918498
DOI	10.1038/s41598-022-17602-4
Web of Science KeyUT	000836651200038
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-17602-4

Clinical Characteristics of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Diagnosed in Patients with Long COVID

フルテキストURL	fulltext.pdf
著者	Tokumasu, Kazuki\| Honda, Hiroyuki\| Sunada, Naruhiko\| Sakurada, Yasue\| Matsuda, Yui\| Yamamoto, Koichiro\| Nakano, Yasuhiro\| Hasegawa, Toru\| Yamamoto, Yukichika\| Otsuka, Yuki\| Hagiya, Hideharu\| Kataoka, Hitomi\| Ueda, Keigo\| Otsuka, Fumio\|
キーワード	general fatigue post-exertional malaise long COVID myalgic encephalomyelitis chronic fatigue syndrome post COVID-19 condition
発行日	2022-06-25
出版物タイトル	Medicina
巻	58巻
号	7号
出版者	MDPI
開始ページ	850
ISSN	1010-660X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35888568
DOI	10.3390/medicina58070850
Web of Science KeyUT	000834490500001
関連URL	isVersionOf https://doi.org/10.3390/medicina58070850

Incidence and Risk of Anti-Resorptive Agent-Related Osteonecrosis of the Jaw after Tooth Extraction: A Retrospective Study

フルテキストURL	fulltext.pdf
著者	Shimizu, Rieko\| Sukegawa, Shintaro\| Sukegawa, Yuka\| Hasegawa, Kazuaki\| Ono, Sawako\| Nakamura, Tomoya\| Fujimura, Ai\| Fujisawa, Ayaka\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
キーワード	anti-resorptive agent-related osteonecrosis of the jaw bisphosphonate denosumab retrospective study risk factor tooth extraction
発行日	2022-07-18
出版物タイトル	Healthcare
巻	10巻
号	7号
出版者	MDPI
開始ページ	1332
ISSN	2227-9032
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35885858
DOI	10.3390/healthcare10071332
Web of Science KeyUT	000831605200001
関連URL	isVersionOf https://doi.org/10.3390/healthcare10071332

The Effectiveness of Pre-Operative Screening Tests in Determining Viral Infections in Patients Undergoing Oral and Maxillofacial Surgery

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Sukegawa, Yuka\| Hasegawa, Kazuaki\| Ono, Sawako\| Nakamura, Tomoya\| Fujimura, Ai\| Fujisawa, Ayaka\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Mukainaka, Yumika\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
キーワード	hepatitis B hepatitis C human immunodeficiency virus pre-operative examination
発行日	2022-07-20
出版物タイトル	Healthcare
巻	10巻
号	7号
出版者	MDPI
開始ページ	1348
ISSN	2227-9032
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35885875
DOI	10.3390/healthcare10071348
Web of Science KeyUT	000832459200001
関連URL	isVersionOf https://doi.org/10.3390/healthcare10071348

A Japanese case of successful surgical resection of cerebral cavernous malformations with a CCM2 mutation

フルテキストURL	fulltext20220708-3.pdf
著者	Nomura, Emi\| Omote, Yoshio\| Takemoto, Mami\| Hishikawa, Nozomi\| Nakano, Yumiko\| Yunoki, Taijun\| Morihara, Ryuta\| Sasaki, Tatsuya\| Akagawa, Hiroyuki\| Abe, Koji\| Yamashita, Toru\|
キーワード	CCM2 cerebral cavernous malformation drug-resistant epilepsy
備考	This is the peer reviewed version of the following article: [Nomura, E, Omote, Y, Takemoto, M, et al. A Japanese case of successful surgical resection of cerebral cavernous malformations with a CCM2 mutation. Neurol Clin Neurosci. 2022; 10: 255- 258. doi: 10.1111/ncn3.12649], which has been published in final form at [https://doi.org/10.1111/ncn3.12649]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
発行日	2022-06-15
出版物タイトル	Neurology and Clinical Neuroscience
巻	10巻
号	5号
出版者	Wiley
開始ページ	255
終了ページ	258
ISSN	2049-4173
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd.
論文のバージョン	author
DOI	10.1111/ncn3.12649
Web of Science KeyUT	000818581000001
関連URL	isVersionOf https://doi.org/10.1111/ncn3.12649

Application of Kampo Medicines for Treatment of General Fatigue Due to Long COVID

フルテキストURL	fulltext.pdf
著者	Tokumasu, Kazuki\| Ueda, Keigo\| Honda, Hiroyuki\| Sunada, Naruhiko\| Sakurada, Yasue\| Matsuda, Yui\| Nakano, Yasuhiro\| Hasegawa, Toru\| Otsuka, Yuki\| Obika, Mikako\| Hagiya, Hideharu\| Kataoka, Hitomi\| Otsuka, Fumio\|
キーワード	general fatigue herbal medicine Kampo medicine long COVID
発行日	2022-05-28
出版物タイトル	Medicina
巻	58巻
号	6号
出版者	MDPI
開始ページ	730
ISSN	1010-660X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35743993
DOI	10.3390/medicina58060730
Web of Science KeyUT	000818259300001
関連URL	isVersionOf https://doi.org/10.3390/medicina58060730

A Case of Mediastinal Localized Malignant Pleural Mesothelioma Successfully Treated by Chemotherapy and Conversion Surgery

JaLCDOI	10.18926/AMO/63746
フルテキストURL	76_3_343.pdf
著者	Maki, Yuho\| Kiriyama, Yosuke\| Ueno, Tsuyoshi\| Suehisa, Hiroshi\| Shigematsu, Hisayuki\| Saeki, Kazuhiko\| Harada, Daijiro\| Kozuki, Toshiyuki\| Teramoto, Norihiro\| Yamashita, Motohiro\|
抄録	Localized malignant mesothelioma is a rare disease and little is known about its treatment strategy. We herein report a case of localized malignant pleural mesothelioma that had infiltrated into the anterior mediastinum, which was successfully treated using chemotherapy and conversion surgery. A 63-year-old man with a mediastinal tumor was referred to our hospital. Pathologic analysis of the biopsy specimen showed malignant mesothelioma. Significant tumor shrinkage by cisplatin and pemetrexed was observed and he underwent radical surgery via a median sternotomy. The patient has been disease free for 12 months.
キーワード	localized mesothelioma mediastinum cisplatin pemetrexed conversion surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	343
終了ページ	347
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790367
Web of Science KeyUT	000823568300015

Analysis of Immunity against Measles, Mumps, Rubella, and Varicella Zoster in Adult Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: A Single-Center Experience

JaLCDOI	10.18926/AMO/63718
フルテキストURL	76_3_247.pdf
著者	Yoshida, Shohei\| Fujii, Nobuharu\| Kamoi, Chihiro\| Kitamura, Wataru\| Fujiwara, Hideaki\| Asada, Noboru\| Nishimori, Hisakazu\| Fujii, Keiko\| Matsuoka, Ken-ichi\| Maeda, Yoshinobu\|
抄録	Vaccine-preventable disease (VPD) infections are more severe in immunocompromised hosts. Vaccination against measles, mumps, rubella, and varicella zoster (VZV) (MMRV) is therefore recommended for hematopoietic stem cell transplantation (HCT) recipients. However, studies on adult HCT recipients with VPD infections are limited. At our institution, we have systematically conducted serological MMRV tests as a part of check-up examinations during long-term follow-up (LTFU) after HCT since 2015. This retrospective study aimed to evaluate changes in the serostatus between before and 2 years after allogeneic HCT. Among 161 patients, the pre-transplant seropositivity was 82.7% for measles, 86.8% for mumps, 84.2% for rubella, and 94.3% for VZV. Among 56 patients who underwent LTFU including serological MMRV tests at 2 years after HCT, the percentages maintaining seroprotective antibody levels for measles, mumps, rubella and VZV were 71.5% (40/56), 51.8% (29/56), 48.2% (27/56), and 60.7% (34/56), respectively. Vaccination was recommended for 22 patients, and 12 were vaccinated. Among the 12 vaccinated patients, rates of seroconversion were examined in 2-6 patients for each of the four viruses. They were 100% (3/3) for measles, 33.3% (1/3) for mumps, 50% (3/6) for rubella, and 0% (0/2) for VZV. Further studies are warranted to clarify the effect of vaccination in adult HCT recipients.
キーワード	vaccine-preventable disease vaccination allogeneic hematopoietic stem cell transplantation adult
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	247
終了ページ	253
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790354
Web of Science KeyUT	000823568300003

Clinical Manifestations of Patients with Influenza Differ by Age: A Prospective, Multi-centered Study in the Setouchi Marine Area

フルテキストURL	K0006571_abstract_review.pdf K0006571_summary.pdf K0006571_fulltext.pdf
著者	髙瀬了輔\|
発行日	2022-03-25
資料タイプ	学位論文
学位授与番号	甲第6571号
学位授与年月日	2022-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School

Prognostic Factors in Endodontic Surgery Using an Endoscope: A 1 Year Retrospective Cohort Study

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Shimizu, Rieko\| Sukegawa, Yuka\| Hasegawa, Kazuaki\| Ono, Sawako\| Fujimura, Ai\| Yamamoto, Izumi\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
キーワード	retrospective cohort study endoscope endodontic surgery prognostic factors
発行日	2022-05-07
出版物タイトル	Materials
巻	15巻
号	9号
出版者	MDPI
開始ページ	3353
ISSN	1996-1944
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35591687
DOI	10.3390/ma15093353
Web of Science KeyUT	000794818400001
関連URL	isVersionOf https://doi.org/10.3390/ma15093353