検索結果 108 件
| JaLCDOI | 10.18926/AMO/56644 |
|---|---|
| フルテキストURL | 73_2_95.pdf |
| 著者 | Ercan, Sabriye| Başkurt, Ferdi| Başkurt, Zeliha| Çetin, Cem| |
| 抄録 | The aim of this study was to examine effect of fatigue levels on functional mobility and balance in middle-aged obese females. The study included 98 healthy females aged 40-60 years with BMI ≥ 30 kg/m2. Self-perceived fatigue was evaluated with a self-administered questionnaire, the Checklist of Individual Strength in Turkish (CIS-T), on which 62.3% of the study subjects identified themselves as fatigued. The body weight and BMI values of fatigued subjects were found to be higher than those of the non-fatigue group (p<0.05). The reported exercise habits of the fatigue group were found to be significantly lower than their non-fatigued peers (p<0.05). The level of functional mobility (Timed Up and Go Test), static balance (One-Legged Stance Test with Eyes Open) and dynamic balance (Functional Reach Test and the 3-meter Timed Tandem Walk Test) were measured, and statistically significant differences were found between fatigue and non-fatigue groups on all of them (p<0.05). In addition, correlations were found between the sub-parameters of the CIS-T scale and the functional tests at |
| キーワード | fatigue obesity mobility balance woman |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 95 |
| 終了ページ | 100 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015743 |
| JaLCDOI | 10.18926/AMO/56454 |
|---|---|
| フルテキストURL | 73_1_15.pdf |
| 著者 | Shioji, Naohiro| Kanazawa, Tomoyuki| Iwasaki, Tatsuo| Shimizu, Kazuyoshi| Suemori, Tomohiko| Kuroe, Yasutoshi| Morimatsu, Hiroshi| |
| 抄録 | We compared the reintubation rate in children who received high-flow nasal cannula (HFNC) therapy to the rate in children who received noninvasive ventilation (NIV) therapy for acute respiratory failure (ARF) after cardiac surgery. This was a retrospective analysis of 35 children who received HFNC therapy for ARF after cardiac surgery in 2014-2015 (the HFNC group). We selected 35 children who had received NIV therapy for ARF after cardiac surgery in 2009-2012 as a control group. The matching parameters were body weight and risk adjustment for congenital heart surgery category 1. The reintubation rate within 48 h in the HFNC group tended to be lower than that in the NIV group (3% vs. 17%, p=0.06). The reintubation rate within 28 days was significantly lower in the HFNC group compared to the NIV group (3% vs. 26%, p=0.04). The HFNC group’s ICU stays were significantly shorter than those of the NIV group: 10 (IQR: 7-17) days vs. 17 (11-32) days, p=0.009. HFNC therapy might be associated with a reduced reintubation rate in children with ARF after cardiac surgery. |
| キーワード | high-flow nasal cannula noninvasive ventilation reintubation congenital heart disease acute respiratory failure |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-02 |
| 巻 | 73巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 15 |
| 終了ページ | 20 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30820050 |
| JaLCDOI | 10.18926/AMO/56181 |
|---|---|
| フルテキストURL | 72_4_419.pdf |
| 著者 | Miyake, Susumu| Sugita, Makio| Okazaki, Tomio| Takenaka, Mieko| Kuwabara, Kentarou| Ogawa, Kazunori| |
| 抄録 | A 22-year-old Japanese male with trisomy 21 was diagnosed with West syndrome at 4 months old. After the suppression of epileptic spasms using adrenocorticotropic hormone therapy, he had complex partial seizures and bilateral frontal epileptic discharges on EEG. Although the introduction of topiramate (TPM) decreased the seizures during wakefulness, frequent episodes of brief eye-opening appeared during sleep while the patient was taking TPM (400 mg/day). EEG showed fast activity at the times of eye-opening. The episodes of eye-opening during sleep and the fast activities disappeared upon TPM discontinuation. This is the first report of TPM-induced microseizures similar to benzodiazepine-induced microseizures. |
| キーワード | topiramate microseizures paroxysmal fast activity side effects seizure aggravation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-08 |
| 巻 | 72巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 419 |
| 終了ページ | 422 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30140091 |
| JaLCDOI | 10.18926/AMO/56076 |
|---|---|
| フルテキストURL | 72_3_297.pdf |
| 著者 | Yamamoto, Hirotsugu| Naito, Hiromichi| Osako, Takaaki| Tsukahara, Kohei| Yamada, Taihei| Yumoto, Tetsuya| Iida, Atsuyoshi| Kosaki, Yoshinori| Oka, Makio| Endo, Fumika| Gochi, Akira| Nakao, Atsunori| |
| 抄録 | A healthy 10-year-old boy vomited during sleep and later complained of abdominal pain; he became drowsy and uncommunicative. At the nearby hospital E.R., he deteriorated rapidly, and his respiratory movements were absent with cardiac arrest. He was immediately resuscitated. Brain MRI showed no abnormalities. EEG revealed an abnormal pattern with recurrent multifocal epileptiform activity over the bilateral occipital and frontal regions during sleep. Based on the clinical/radiological findings we diagnosed Panayiotopoulos syndrome (PS), a benign form of early-onset pediatric epilepsy characterized by autonomic symptoms. Lifethreating cardiopulmonary arrest is rare in PS, but long seizure duration of PS may associate with apnea and bradycardia. |
| キーワード | pediatric epilepsy autonomic symptom cardiac arrest afebrile seizure EEG |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-06 |
| 巻 | 72巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 297 |
| 終了ページ | 300 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29926008 |
| フルテキストURL | K0005603 abstract_review.pdf K0005603_summary.pdf K0005603_other1.pdf K0005603_other2.pdf K0005603_fulltext.pdf |
|---|---|
| 著者 | Acing Habibie Mude| |
| 発行日 | 2017-09-29 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5603号 |
| 学位授与年月日 | 2017-09-29 |
| 学位・専攻分野 | 博士（歯学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| タイトル（別表記） | The 2016 Incentive Award of the Okayama Medical Association in Neuroscience (2016 Niimi Prize) |
|---|---|
| フルテキストURL | 129_85.pdf |
| 著者 | 柴田 敬| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-08-01 |
| 巻 | 129巻 |
| 号 | 2号 |
| 開始ページ | 85 |
| 終了ページ | 87 |
| ISSN | 0030-1558 |
| 関連URL | https://doi.org/10.4044/joma.129.85 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.85 |
| NAID | 130006039369 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yoshihara, S.| Fukuda, H.| Tamura, M.| Arisaka, O.| Ikeda, M.| Fukuda, N.| Tsuji, T.| Hasegawa, S.| Kanno, N.| Teraoka, M.| Wakiguchi, H.| Aoki, Y.| Terada, A.| Hasegawa, M.| Manki, A.| Igarashi, H.| |
| キーワード | salmeterol/fluticasone combination asthma infant preschool children nighttime sleep disorder score long-acting beta-agonist inhaled corticosteroid |
| 発行日 | 2016-07 |
| 出版物タイトル | Drug Research |
| 巻 | 66巻 |
| 号 | 7号 |
| 出版者 | Georg Thieme |
| 開始ページ | 371 |
| 終了ページ | 376 |
| ISSN | 2194-9379 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Georg Thieme Verlag |
| 論文のバージョン | publisher |
| PubMed ID | 27273710 |
| DOI | 10.1055/s-0042-108852 |
| Web of Science KeyUT | 000379389100007 |
| 関連URL | isVersionOf https://doi.org/10.1055/s-0042-108852 |
| 著者 | 小林 勝弘| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| タイトル（別表記） | Identification of the adipokine ‘vaspin’ and its significance in metabolic syndrome |
|---|---|
| フルテキストURL | 128_103.pdf |
| 著者 | 和田 淳| |
| キーワード | metabolic syndrome adipokine atherosclerosis endothelial cells apoptosis |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2016-08-01 |
| 巻 | 128巻 |
| 号 | 2号 |
| 開始ページ | 103 |
| 終了ページ | 109 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.128.103 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2016 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.128.103 |
| NAID | 130005262534 |
| フルテキストURL | K0005296_abstract_review.pdf K0005296_fulltext.pdf |
|---|---|
| 著者 | 時信 亜希子| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5296号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/53525 |
|---|---|
| フルテキストURL | 69_3_177.pdf |
| 著者 | Hoshijima, Mitsuhiro| Honjo, Tadashi| Moritani, Norifumi| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi| |
| 抄録 | This article reports the case of a 44-year-old male with skeletal Class III, Angle Class III malocclusion and unilateral crossbite with concerns about obstructive sleep apnea syndrome (OSAS), esthetics and functional problems. To correct the skeletal deformities, the maxilla was anteriorly repositioned by employing LeFort I osteotomy following pre-surgical orthodontic treatment, because a mandibular setback might induce disordered breathing and cause OSAS. After active treatment for 13 months, satisfactory occlusion was achieved and an acceptable facial and oral profile was obtained. In addition, the apnea hypopnea index (AHI) decreased from 18.8 preoperatively to 10.6 postoperatively. Furthermore, after a follow-up period of 7 months, the AHI again significantly decreased from 10.6 to 6.2. In conclusion, surgical advancement of the maxilla using LeFort I osteotomy has proven to be useful in patients with this kind of skeletal malocclusion, while preventing a worsening of the OSAS. |
| キーワード | LeFort I osteotomy maxillary advancement unilateral crossbite obstructive sleep apnea syndrome |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 177 |
| 終了ページ | 182 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101194 |
| Web of Science KeyUT | 000356903000007 |
| 著者 | Kobayashi, Tomoko| Suzuki, Etsuji| Oksanen, Tuula| Kawachi, Ichiro| Takao, Soshi| |
|---|---|
| 発行日 | 2014-01-31 |
| 出版物タイトル | PLoS ONE |
| 巻 | 9巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 曽我部 咲| 鈴木 真奈美| 佐伯 綾希子| 井上 里加子| 林 泰資| |
|---|---|
| 発行日 | 2014-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 30巻 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/bgeou/51109 |
|---|---|
| タイトル（別表記） | Association Between Three-year Longitudinal Changes in Physical Strength in Children with Their Build, Health Habits, and Psychophysical Health Indexes. |
| フルテキストURL | bgeou_153_081_087.pdf |
| 著者 | 足立 稔| 酒向 治子| 笹山 健作| |
| 抄録 | In this study we examined the association between longitudinal changes in schoolchildren＇s physical strength with their build, health habits, and psychophysical health index scores. Students (n= 195) were followed for three years, from the fifth to the eighth grade. Setting as a baseline the students＇ results on the Ministry of Education, Culture, Sports, Science and Technology＇s new physical strength test, we extracted data on those students whose physical strength relatively improved (improved group: 28 boys, 53 girls) and on those whose strength relatively declined (declined group: 15 boys, 16 girls). Build, health habits, and psychophysical health index scores were compared between the two groups. It was found that, although there were no significant differences in eating habits or sleeping habits between the two groups, compared to the improved group, the declined group was more likely to be either obese or underweight, have short durations of intense exercise and total exercise, and longer duration of watching television or videos. The declined group also showed poorer psychological health status, such as lower self-efficacy and higher anxiety. These findings indicate that children with good exercise habits, such as consistently engaging in a adequate physical activities that include intense exercise, will have improved physical strength outcome over time, whereas those children with few regular exercise habits and whose strength will not improve over time, will show outcomes such as polarization of body weight (obesity and underweight tendencies) and poorer psychological health status. |
| キーワード | 子ども 体力 生活習慣 縦断的研究 |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2013-07-25 |
| 巻 | 153巻 |
| 開始ページ | 81 |
| 終了ページ | 87 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005324823 |
| JaLCDOI | 10.18926/AMO/48686 |
|---|---|
| フルテキストURL | 66_4_317.pdf |
| 著者 | Pak, Wing| Takayama, Fusako| Hasegawa, Azusa| Mankura, Mitsumasa| Egashira, Toru| Ueki, Keiji| Nakamoto, Kazuo| Kawasaki, Hiromu| Mori, Akitane| |
| 抄録 | This study aimed to investigate the therapeutic effects of the water extract of leaves of Vitis coignetiae Pulliat (VCPL) on nonalcoholic steatohepatitis (NASH) with advanced fibrosis, as our previous study exhibited its preventive effect on NASH. The NASH animal model [PCT/JP2007/52477] was prepared by loading recurrent and intermittent hypoxemia stress to a rat with fatty liver, which resembled the condition occurring in patients with obstructive sleep apnea (OSA) and fatty liver, who have a high incidence of NASH. Intermittent hypoxemia stress is regarded as a condition similar to warm ischemia followed by re-oxygenation, which induces oxidative stress (OS). The daily 100 or 300mg/kg VCPL administrations were performed for 3 weeks perorally beginning at the time of detection of advanced liver fibrosis. The therapeutic efficacy of VCPL on NASH was demonstrated by the reduction of the leakage of hepato-biliary enzymes and the amelioration of liver fibrosis. The OS elevation in NASH rats was measured based on the derivation of reactive oxygen species from liver mitochondrial energy metabolism and on the decrease in plasma SOD-like activity. The aggravation of inflammatory responses was demonstrated by the neutrophil infiltration (elevated myeloperoxidase activity) and the progression of fibrosis in the livers of NASH rats. In addition, the NASH rats without VCPL treatment also exhibited activation of nuclear factor-κB, a key factor in the link between oxidative stress and inflammation. All of these changes were reduced dose-dependently by the VCPL administration. These findings indicate that VCPL may improve hepatic fibrosis or at least suppress the progression of NASH, by breaking the crosstalk between OS and inflammation. |
| キーワード | non-alcoholic steatohepatitis antioxidative oxidative stress anti-inflammation Vitis coignetiae Pulliat |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-08 |
| 巻 | 66巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 317 |
| 終了ページ | 327 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22918204 |
| Web of Science KeyUT | 000307918900004 |
| JaLCDOI | 10.18926/AMO/48259 |
|---|---|
| フルテキストURL | 66_2_93.pdf.pdf |
| 著者 | Ochiai, Hirotaka| Shirasawa, Takako| Shimada, Naoki| Ohtsu, Tadahiro| Nishimura, Rimei| Morimoto, Aya| Hoshino, Hiromi| Tajima, Naoko| Kokaze, Akatsuki| |
| 抄録 | Although a number of studies have investigated the relationship of sleep duration to overweight and obesity, studies conducted among population-based elementary schoolchildren have been limited in Japan. The aim of the present study was to investigate the relationship between sleep duration and overweight among elementary schoolchildren in Japan. The study subjects were all fourth-grade schoolchildren (9 or 10 years of age) in Ina-town, Saitama Prefecture, Japan from 1999 to 2008. Information concerning each subjectʼs sex, age, and lifestyle was obtained using a self-administered questionnaire, while measurements of his or her height and weight were carried out. Childhood overweight was determined according to the definition established by the International Obesity Task Force. Data from 3,433 children were analyzed. In logistic regression analysis, a statistically significant dose-response relationship was observed between sleep duration and overweight among boys (p for trend＝0.014) but not among girls (p for trend＝0.149). Short sleep duration was associated with childhood overweight, and the sex difference in the association was observed. These findings suggested that it is important to consider sleep duration as part of any program to prevent overweight among elementary schoolchildren, especially among boys. |
| キーワード | sleep overweight schoolchildren Japan |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-04 |
| 巻 | 66巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 93 |
| 終了ページ | 99 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22525467 |
| Web of Science KeyUT | 000303175300002 |
| JaLCDOI | 10.18926/AMO/48080 |
|---|---|
| フルテキストURL | 66_1_41.pdf |
| 著者 | Ohtsu, Tadahiro| Kaneita, Yoshitaka| Ishimura, Yohei| Aritake, Sayaka| Mishima, Kazuo| Uchiyama, Makoto| Akashiba, Tsuneto| Uchimura, Naohisa| Nakaji, Shigeyuki| Munezawa, Takeshi| Shimada, Naoki| Kokaze, Akatsuki| Ohida, Takashi| |
| 抄録 | Little research has been done on the association between relaxation and health. In the present study, by conducting a nationwide cross-sectional survey, we aimed to obtain scientific data on the preferable forms of relaxation for health promotion, and to clarify the associations between specific recreational activities and self-perceived mental and physical health. We selected 4,000 households by stratified random sampling from across Japan in November 2009 and used the interview method to collect data (number of subjects:2,206). The questionnaire contained items on sleep, recreation status, recreational activities, and self-perceived mental and physical health status. We obtained responses from 1,224 adults (response rate:55.5%). Insufficient rest from sleep, short sleep duration (＜6h/day), ineffective use of free time, and less free time used for activities other than rest showed independent positive associations with poor mental and physical health. The results of the logistic regression analyses showed significantly low adjusted odds ratios with regard to the status of poor mental and physical health for outings/walking among men (0.33 [95% confidence interval;0.16-0.68] and 0.49 [0.26-0.90], respectively), and for community activities among women (0.19 [0.04-0.79] and 0.27 [0.09-0.77], respectively). Relaxation for the promotion of health should include both passive relaxation (rest) and active relaxation (recreation). In addition, ensuring sufficient sleep duration is important for passive relaxation, and engaging in outings/walking for men and community activities for women are important for active relaxation. |
| キーワード | passive relaxation active relaxation recreational activity self-perceived health |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-02 |
| 巻 | 66巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 41 |
| 終了ページ | 51 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22358138 |
| Web of Science KeyUT | 000300800700006 |
| JaLCDOI | 10.18926/AMO/46631 |
|---|---|
| フルテキストURL | 65_3_193.pdf |
| 著者 | Kawaura, Akihiko| Tanida, Noritoshi| Akiyama, Junichi| Nonaka, Kouji| Mizutani, Masatoshi| Sawada, Kenji| Nakagawa, Kimie| Tsugawa, Naoko| Izumi, Keisuke| Ii, Kunio| Okano, Toshio| Takeda, Eiji| |
| 抄録 | Sixty-three male 5-week-old Syrian hamsters received the carcinogen N-nitrosobis(2-oxopropyl)amine (BOP) s.c. in 5 weekly injections (the first, 70mg/kg body, and the remaining, 20mg/kg each). The hamsters that received BOP were given intragastric administration of 0.2ml of medium chain triglyceride (MCT) with or without 0.04μg of 1α-hydroxyvitamin D3 [1α(OH)D3] through a feeding tube for 12 weeks. Thus, 3 groups were assigned:Group 1;BOP alone (n＝20), Group 2;BOP＋MCT (n＝18) and Group 3;BOP＋1α(OH)D3 (n＝25). The mean body weight of Group 3 was lower than those of Groups 1 and 2 at the end of the experiment (p＜0.001,Tukey-Kramer HSD test). At the end of week 12, all surviving hamsters were put to sleep. The incidences of liver tumors were 80%, 72% and 32% in Groups 1, 2 and 3, respectively. The incidence of tumors in Group 3 was significantly lower than in Group 1 and Group 2 (p＜0.05, χ2-test). All tumors were cholangiocarcinoma. These results indicated that BOP-induced cholangiocarcinogenesis was suppressed by the supplemental administration of 1α(OH)D3. |
| キーワード | 1α-hydroxyvitamin D3 N-nitrosobis(2-oxopropyl)amine cholangiocarcinogenesis Syrian hamsters |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-06 |
| 巻 | 65巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 193 |
| 終了ページ | 197 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21709717 |
| Web of Science KeyUT | 000292017500006 |
| JaLCDOI | 10.18926/AMO/43826 |
|---|---|
| フルテキストURL | 65_1_21.pdf |
| 著者 | Tamura, Hiroko| Suzue, Takeshi| Jitsunari, Fumihiko| Hirao, Tomohiro| |
| 抄録 | The aim of this study was to evaluate the carotid arterial intima-media thickness (IMT) and its relation to clinical parameters in Japanese children. Fifty-two healthy children (39 boys and 13 girls), aged 6-14 years, were enrolled in this cross-sectional investigation study. IMT of the common carotid artery was determined using ultrasonography. We also investigated anthropometric parameters, blood pressure (BP), lifestyles and blood examinations. The mean value of IMT was 0.4±0.1mm, which was lower than the normal value (1.0mm) in adults. IMT was positively correlated with age (r＝0.340) and height (r＝0.346) in boys, while it was positively correlated with body mass index (BMI) (r＝0.584) and diastolic BP (DBP) (r＝0.563) in girls. In addition, IMT was associated with sleeping hours and hours of watching television (TV) by using stepwise regression analysis. In conclusion, IMT increased with aging, and it was linked to some clinical parameters of atherosclerosis and lifestyles in children. Therefore, this reference data will be helpful for future assessment of age-related change in Japanese children in clinical practice, and IMT might be a good predictor of atherosclerosis in Japanese children. |
| キーワード | intima-media thickness (IMT) lifestyle Japanese children proportional hazards models atherosclerosis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-02 |
| 巻 | 65巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 21 |
| 終了ページ | 25 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21339792 |
| Web of Science KeyUT | 000287620500003 |
| 著者 | 更井 啓介| |
|---|---|
| 発行日 | 1957-12-31 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 69巻 |
| 号 | 12号 |
| 資料タイプ | 学術雑誌論文 |