検索結果 18634 件
| 著者 | 濱野 亮輔| 大塚 眞哉| 木村 裕司| 西江 学| 徳永 尚之| 宮宗 秀明| 常光 洋輔| 稲垣 優| 岩川 和秀| 岩垣 博巳| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 小林 由佳| 山田 美佐| 藤井 裕美| 甲 由紀子| 魚谷 いづみ| 田本 真理子| 名田 正子| 村井 裕之| 角 英| 岩垣 博巳| 友田 純| 斎藤 信也| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 原田 聡介| 武本 充広| 吉尾 浩太郎| 児島 克英| 片山 敬久| 勝井 邦彰| 黒田 昌宏| 松尾 俊彦| 金澤 右| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 能祖 一裕| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 藤原 俊義| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 児島 亨| 橋本 悠里| 香川 俊輔| 田中 紀章| 浦田 泰生| 藤原 俊義| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 三好 耕| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 山下 徹| 神谷 達司| 出口 健太郎| 稲葉 俊東| 張 漢哲| 商 敬偉| 宮崎 一徳| 大塚 愛二| 片山 泰朗| 阿部 康二| |
|---|---|
| 発行日 | 2010-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 122巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/40432 |
|---|---|
| タイトル（別表記） | MEDICAL STUDIES ON CHONDROITlN SULFATE (IV) DISTRIBUTION OF CHONDROITIN SULFATE LABELED WITH S(35) IN ANIMAL BODY |
| フルテキストURL | pitsr_012_042_051.pdf |
| 著者 | 岸田 專蔵| |
| 抄録 | 0.1 ml. of the 1% solution of chondroitin sulfate labeled with S(35) was administered to mice intraperitoneally or 0.5 ml. was given per orally with gastric tube to another gronp of mice. Each two mice were killed every one, two, six, twelve, twenty four and fouty eight hours after the injection respectively and after a series of daily injection for a week samples of blood, lungs, heart, liver, kidneys, skin, muscles bones, spleen, brain, stomach and ntestines were taken from these animals. Radioactivity of S(35) was measured by BaSO(4) method using Lanritsen's electroscope. 1) The highest activity in blood was observed by about two hours after the injection, while in per oral administration it was reached after six hours. absorption of perorally administered chondroitin sulfate was estimated to reach roughly 35% abter 6 hours. 2) The excretion of labeled chondroitin sulfate seemed to be done from kidneys. The greater part was excreted in six hours and then the decrease in the activity of kidneys became slower. 3) Muscles and skin showed a considerable activity in 1-2 hours. A marked decrease was seen after six hours, then their activity seemed to remain unchanged. 4) Radioactivity of skeleton rose gradually, reached its maximum in twelve hours, and then had a tendency to show constant value. 5) In liver, spleen and brain highest activity was observed two hours after the injection. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-09 |
| 巻 | 12巻 |
| 開始ページ | 42 |
| 終了ページ | 51 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40422 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002509308 |
| JaLCDOI | 10.18926/40348 |
|---|---|
| タイトル（別表記） | MEDICAL STUDIES ON CHONDROITIN SULFATE (III) |
| フルテキストURL | 013_036_041.pdf |
| 著者 | 大島 良雄| 外園 正純| |
| 抄録 | 2-5cc. of 1% Rodium chondroitin-sulfate solution subcutaneouRly or 2cc. of 5% solution intraveneously was administered to 37 cares of painful disorders such as headache, backache or arthralgia. A marked improvement was obtained in 12 cares and a moderate result was seen in 16 cases. No definite change was proved concerning blood pressure in the patients and detoxicating effect in animal experiment. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-12 |
| 巻 | 13巻 |
| 開始ページ | 36 |
| 終了ページ | 41 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40340 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532453 |
| JaLCDOI | 10.18926/40332 |
|---|---|
| タイトル（別表記） | MEDICAL STUDIES ON THE RURAL PEOPLE (II) A STUDY ON THE INCIDENCE OF STRUMA IN THE SOUTH-WESTERN RURAL DISTRICTS OF OKAYAMA PREFECTURE, JAPAN |
| フルテキストURL | pitsr_014_051_056.pdf |
| 著者 | 森永 寛| |
| 抄録 | The author investigated the thyroid glands of 1480 school children (aged from 6 to 14) living in the vicinity of Yakage, the south-western rural district of Okayama Prefecture, and 1516 out-patients of Yakage Hospital, in 1950. The incidence of struma among the school children was 4.6 per cent and among the out-patients 4.7% on an average, and the percentage of struma in the spring (7.8%) was higher than in the summer (2.98%). This result suggests that thyroid glands are in some way susceptible to seasonal influences, and it is therefore necessary to consider the effect of season during investigation. The white blood pictures of seven patients showed no specific findings. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1954-03 |
| 巻 | 14巻 |
| 開始ページ | 51 |
| 終了ページ | 56 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462907 |
| JaLCDOI | 10.18926/40331 |
|---|---|
| タイトル（別表記） | MEDICAL STUDIES ON THE RURAL PEOPLE (I) CLINICAL AND STATISTICAL OBSERVATIONS ON HOOKWORM DISEASE IN RURAL DISTRICTS |
| フルテキストURL | pitsr_014_045_050.pdf |
| 著者 | 森永 寛| |
| 抄録 | The author studied statistically 160 cases of hookworm infection who had been admitted to Misasa Branch of Okayama University Hospital, Misasa Hot Springs in Tottori prefecture, during 1946~1949 and 162 cases of out-patients with anchylostomiasis in Yakage Hospital, Okayama Prefecture, during 1949～1950. The clinical findings were as follows: (1). Females showed a higher incidence than males and the incidence ratio of infected persons to total out-patients increased with age up to the 50~69 years group. (2). The most patients consulted our hospital for the first time in April～May and in August, and 62 per cent of cases came within 3 months scince they had noticed disorders in some way, but 22% remained at home without medical cure more than a year. (3). Chief subjective complaints were palpitation of heart (35.3%), lassitude of legs (31.2%), pains in the abdomen (22.9%), feeling of dizziness (21.6%) and so on. (4). Laboratory findings: The total number of erythrocytes was between 1.23 and 5.54 millions per cubic millimeter and a moderate anemia almost always developed in the hookworm disease (77.9% of all cases). The number of white cells was normal or slightly increased. Relative or absolute eosinophilia was recognized in 83.5% of all patients. Wassermann's test was positive in 20%, and Takata's reaction positive in 53% of the cases. The acidity of the gastric juice was lower than normal. Hypo- and anacidity were verified in 58%. Both albumen and urobilinogen test in urine were positive in 5.4% of 61 cases. Sugar in none. (5). Treatment: Thymol, tetrachlorethylene and oil of chenopodium were used alternately to remove the worms. The eggs in stool became negative after 3-4 times of the administration of anthelmintics in 76 per cent of 151 cases. As mentioned above, the patients infected with hookworm had various functional disorders of bodies, but they consulted the hospital only when the farmer's busy season began and their trouble became unbearable. And then the recovery of anemia took a month or two. Prof. Kitayama reported that the cold environment under 9°C. in the winter had perished the larva of hookworm in the soil. From these viewpoints, the author proposed that examination and cure of hookworms should be carried out in the winter, the slack season for farming, to prevent the fall of working ability due to anchylostomiasis during the busy farming seasons. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1954-03 |
| 巻 | 14巻 |
| 開始ページ | 45 |
| 終了ページ | 50 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40330 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462906 |
| JaLCDOI | 10.18926/40270 |
|---|---|
| タイトル（別表記） | DIE KLINISCHEN UND EXPERIMENTELLEN UNTERSUCHUNGEN ÜBER DIE PELOIDTHERAPIE BEI GYNÄKOLOGISCHEN ENTZÜNDUNGEN |
| フルテキストURL | 020_001_041.pdf |
| 著者 | 岡田 俊郎| |
| 抄録 | Die resortive Behandlung bei schwerheilbaren chronischen Entzündungen der Adnexe und des Uterus besteht aus verschiedenen Wärmeapplikationsmethoden. Effekt der Peloidtherapie als eine von diesen Methoden wurde untersucht. Die Untersuchung besteht aus klinischer Beobachtung über die Peloidpackung und tier experimentellem Studium über Peloidbad. A) Über die Peloidpackung. 1. Heileffekt der Packung. 35 Fälle, die an chronischer Entzündung der Adnexe und des Uterus gelitten hatten, wurden mit warmer Peloidpackung an Lenden oder Unterbauch täglich einmal für 2 oder 3 Wochen behandelt. Bei den 28 Fällen von diesen 35 Fällen wurde die gute Folge, wie zum Beispiel Nachlass der Schmerzen und der Induration, bemerkt, Da einige Fälle von diesen 28 Fällen schwache Reaktion auf die anderen verschiedenen Therapie wie Ultrakurzwellenbestrahlung gezeigt hatten, Packung mit Peloid muss eine erfolgreichste Therapie in besonderen Fällen sein, 2, Physiologische Untersuchungen über den Einfluss der Packung bei obigen Kranken, Gesteigerte Blutsenkungsgeschwindigkeit normalisierte sich, und Leukozytenzahl zeigte keine Zeichen der Verschlechteung während der Kur, Keine nennenswerte Veränderung des Elektrokardiogramms wurde während und nach Applikation der Peloid gefunden, und bei Kranken mit hohem Blutdruck fiel der Blutdruck vorübergehend während Applikation der Peloid, Steigerung der Hauttemperatur und der Uterustemperatur bei Packung waren grösser als bei Ultrakurzwellenbestrahlung und Heissluftbad, und diese Erscheinungen wurden auch von tierexperimentellen Untersuchungen festgestellt, Ausscheidung der Phenolsulfonphthalein, die in die Bauchhöhle des Kaninchens sich eingespritzt hatte, wurde von Packung an Unterbauch beschleunigt, So stellt diese klinischen und tierexperimentellen Untersuchungen fest, dass Peloidpackung stark resorptiv durch ihre hyperämisierenden Wirkung nach die Tiefe des Krankheitsherdes ist, und zwar es den Kranken zu keiner Last in verschiedenen Seiten fallt, B) Über das Peloidbad, Verfasser hatte ein Stückchen der spongiOsen Gelatine, die üblich als blutstillendes Material bei Operation gebraucht wird, an Peritoneum der Ratten angenäht, und liess diese Ratten die Peloidbäder täglich einmal 20 minutenlang für 4 Wochen nehmen Inzwischen wurden die Ratten wöchentlich getötet, und die spongiöse Gelatine wurde mit umgebener Granulation aus Bauchhöhle herausgenommen, und dann wurde histologisch untersucht. Gleichzeitig wurden Arten der freien Zellen in der Bauchhöhle und die Neutralrotfärbung:::intensität der Hystiozyten in lockerem Bindegewebe der Unterhaut als Merkmal für Abwehrkraft des Organismus untersucht, Es war festgestellt, dass bei Peloidbädern der Verlauf der durch spongiöse Gelatine hervorgerufene Entzündung sich verkürzt, und das Stückchen der Gelatine wird schnell abgesorviert, und zugleich Abwehrkraft sich steigert, Bei diesen Experimente wurden die stark sauere sulfurhaltge Quellenschlamme (Konyajigoku zu Beppu) und die neutrale Schlamme der Seeboden (Toogooike zu Tottoriken) gebraucht, aber kein wesentlicher Wirkungsunterschied zwischen beide Schlamme wurde gefunden. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1958-01 |
| 巻 | 20巻 |
| 開始ページ | 1 |
| 終了ページ | 41 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532504 |
| JaLCDOI | 10.18926/40267 |
|---|---|
| タイトル（別表記） | Studies on Balneotherapy of Gynecological Chronic Inflammations |
| フルテキストURL | pitsr_021_001_046.pdf |
| 著者 | 石井 氻| |
| 抄録 | The effects of balneotherapy on gynecological chronic inflammations were examined both clinically and experimentally. Clinical study. Statistical observations were made on the patients with gynecological diseases who visited the spa of Misasa. It was ascertained that, among them, the patients with gynecological chronic inflammati on whose chief complains were hypogastric and Lumbar pains were most common and that, by balneotherapy, their conditions were frequently improved both subjectively and objectively. Experimental study. An experimental foreign body inflammation was evoked by inserting a Sponge into the abdominal cavity of an adult female rat and the effects of hot-spring bath were examined. Acceleration of the absorption of the inflammation, enhancement of phagocytosis of the subcutaneous histiocytes, activation of the fibrohistiocytic system of the subcutaneous connective tissue, and acceleration of return of the free cells in the abdominal cavity were proved. Furthermore, comparative studies were made on the effects of various artificial mineral waters and ultra short waves. It was found that, though they were less effective than natural mineral water, artificial strong saline water, artificial sulfur water, artificial sulfate water, artificial iron water and ultra short waves were effective and that artificial weak saline water, artificial bicarbonate water, artificial humimic acid water, artificial alkaline water, and artificial acidic water were as effective as fresh water. Compared with hot bath, insensible bath was more effective. No significant difference of therapeutic effect was found by bathing once a day or three times a day. In short, balneotherapy had a facilitatory action on the absorption of the inflammatory changes in the abdominal cavity. This should be ascribed not only to the increase in the deep blood flow by warming but also to the general defence mechanism enhanced by cutaneous stimulation. Some differences were also assumed depending on the ions contained in the mineral waters. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1958-04 |
| 巻 | 21巻 |
| 開始ページ | 1 |
| 終了ページ | 46 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462893 |
| JaLCDOI | 10.18926/40265 |
|---|---|
| タイトル（別表記） | Studies on Paper-Analysis in the Field of Balneology (I) Studies on Iron in Serum by Means of Parper-Electrophoresis and Paper-Chromatography |
| フルテキストURL | 022_037_054.pdf |
| 著者 | 石橋 丸応| |
| 抄録 | 1. The author showed by means of paper-electrophoresis using o-nitrosoresorcinmonomethylether (hereafter N. R. M. E.), a colourdeveloping reagent, that iron in serum combines with β-fraction of serum protein. 2. The author proposed a new method for the determination of serum iron by means of paper-chromatography. Procedure is as follows. In a centriguged tube, 0.5 ml. of clear serum is taken, acidified with 0.15 ml. of 20% HNO(3), and allowed to stand for 20 minutes. After addition of 0.2 ml. of saturated solution of CH(3)COONa and 1 ml. of acetic acid-sodium acetate buffer solution (pH: 3.8), the mixture is kept for at least 10 min. and filtered through Toyo-filter-paper No.5 A. The clear filtrate is taken in a stoppered test tube (the inside diameter: 1.2 cm.; height: 15 cm.). To this filtrate are added 0.2 ml. of 20% Hydroxylamine hydrochloride and 0.25 ml. of saturated aqueous solution of N. R. M. E. After being allowed to stand for at least 20 min., the mixture is shaken with 5 ml. of carbon tebrachloride. Then the excess of N. R. M. E. is removed. The supernatant aqueous solution (0.2 ml.) is used for a determination sample. The sample is placed on the paper (Toyo,filter-paper No.51 or 50) in a thin line at a distance of 10 cm. from the edge, and the spots are developed with 90 % ethylalcohol. After development for 4-6 hours, a green-coloured linear spot appsars at a distance of 12-16 cm. from the origin-point. Spot intensity at 670 mμ is measured with Natsume's densitometer, and from this, concentration of Fe can be estimat.ed on the standard graph (Fig. 5). 3, Effects of radioactive thermal spring bathing and internal use of vitriol water upon serum iron levels were studied with the result.s as follows. The above-mentioned author's method of determining the iron level in a small amount of serum is very convenient in investigating iron metabolism in the field of balneotherapy. The author examined changes of iron levels in serum after radioactive thermal bathing as well as after internal use of acid vitriol water. a) The iron levels in serum were maasurecl by the author's method before and 5, 30 and 60 minutes after the radioactive thermal bath (Rn-content: 10-30 Mache, 42-3°C., for 10 min,). The iron levels in the serum of healthy subjects showed no significant change after the thermal bathing. b) Yanahara Mineral Water (an acid vitriol water, pH; 2.2) contains 0.045 gm. of Cl(-), 12.35 gm. of SO(4)(--), 2.5 gm. of Fe(++)+Fe(+++), 0.0938 gm. of Al(+++) and 0.0001 gm. of Cobalt in one liter. i) Thirty ml. of Yanahara, water diluted with plain water to 200 ml. (Fe(++) content: ca. 75 mg.) and administered to health fasting subjects orally. As a control matter, 0.65 gm. of Glukon-F powder (Fe(++) content.: ca. 75 mg.) was then given. Blood samples were taken from the cubital vein before and 1, 3 and 6 hours after the intake of the dtriol water. Iron contents of the serum samples were measured by the author's paper chromatographic method. The results were shown in the table and the figure. The iron contents of the serum after the intake of the mineral water were higher than in the case of the control. ii) Two ml. of Yanahara vitriol water was administered to rabbits with the aid of a stomach tube, and serum iron levels wera determined before and 1, 3, 4 and 6 hours after the administration. An amount of 0.05 gm. of Glukon-F powder was dissolved in 5 ml. of plain water, and this solution was given to rabbits as a control. After the internal use of vitriol water, iron levels in serum rose and remained unexpactedly high for about 1-4 hours, in a manner that did not. correspond to the amount of iron in the given mineral water. So that it was suspected that the iron originally contained in the living subjects had been mobilized by the intake of vitriol water. Iron levels in serum after administration of a solution of Glukon-F powder were lower than in the case of the mineral water. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1958-07 |
| 巻 | 22巻 |
| 開始ページ | 37 |
| 終了ページ | 54 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40263 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532359 |
| JaLCDOI | 10.18926/40253 |
|---|---|
| タイトル（別表記） | Studies on Paper-analysis in the Field of Balneology. (3) The Changes of the Serum Protein Fractions and Lipoprotein Fractions Following the Bathing in Radioactive Hot Spring |
| フルテキストURL | 024_054_079.pdf |
| 著者 | 石橋 丸応| |
| 抄録 | I. Some fundamental conditions and procedures on filter-paper electrophoresis were investigated. The electrophoretic apparatus of Natsume Seisakusho and Toyo No. 51 filter-paper were used. Electrophoresis was carried out under the current of 0.25 mA/cm. in 300 Volt during 5 hours, using veronal buffer pH 8.6 (μ=0.05). In measuring of serum protein fractions, the adequate volume of the materials loaded is in the range of 0.005～0.01 ml. and in the case of lipoprotein, 0.02 ml. of serum is used. Paper-strip was stained with bromophenol blue or sudan black B, then making it transparent with heat-solved paraffin and photometered by Nataume's densitometer. The reproducibility of the above-mentioned method with a confidence of 99% was as follows: Serum protein fractions Albumin 53.4±1.8% α(1)-Globulin 3.3±0.3 α(2)-Globulin 6.0±0.5 β-Globulin 12.2±0.7 γ-Globulin 25.1±1.1 Serum lipoprotein fractions α 20.6±2.6% β+γ 79.4±2.6 II. Changes in serum protein fractions and lipoprotein fractions following the radioactive hot spring bathing were as follows: 1). In rabbits, the albumin-fraction of serum protein increased after a series of baths in radioactive hot spring, and the β- and γ-globulin-fractions decreased. 2). By cholesterol-feeding, the albumin-fraction of serum protein of rabbits decreased and the β- and γ-globulin-fractions increased significantly but when a series of baths was carried out in cholesterol-fed rabbits the decrease in the albumin-fraction was slighter than the former. 3). α-globulin-fraction of serum lipoprotein increased after single bathing in radioactive hot spring and (β+γ) -globulin-fractions showed an inverse change, but the changes of lipoprotein-fractions following a series of baths were not remarkable. 4). By cholesterol-feeding, the ratio of lipoprotein-fractions (β+γ/α) increased, but the ratio tended to decrease following a series of baths in radioactive hot spring. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-01 |
| 巻 | 24巻 |
| 開始ページ | 54 |
| 終了ページ | 79 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40250 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532366 |
| JaLCDOI | 10.18926/40252 |
|---|---|
| タイトル（別表記） | Studies on Paper-analysis in the Field of Balneology. (II) 1. A New Method for the Determination of Cobalt in Blood. 2. Effects of Radioactive Thermal Bathing and Internal Use of Vitriol Water upon Cobalt Levels in Blood. |
| フルテキストURL | 024_029_053.pdf |
| 著者 | 石橋 丸応| |
| 抄録 | 1. A new method for the determination of cobalt in blood. The author proposed a new method for the determination of cobalt in blood by means of paper-chromatography. The procedure is follows. In a Kjeldahl colben, 5 m!. of blood is taken, and turned into wet ash with 3 ml. of HNO(3), 0.5 ml. of H(2)SO(4) and 1.5 ml. of HClO(4) and the ash aqueus solution is then neutralized with ammonium hydroxid, the neutralization being indicated by the development of color of 0.1% of p-nitrophenol (one drop) added to the solution. After addition of 2 ml. of 40% ammonium citrate, 0.5 ml. of 20% Na(2)S(2)O(3), 3～5 drops of H(2)O(2) and 1 ml. of o-nitrosoresorcine monomethyl ether (hereafter N.R.M.E.), the mixture is left for at least 15 minutes and the aqueus solution is taken in a stoppered test tube (inside diameter: 1.3 cm., hight: 16.5 cm.). The mixture is shaken with 2 ml. of carbon tetrachloride. Carbon tetrachloride is shaken with 5 ml. of 20% Na(2)CO(3) solution. Then the excess of N.R.M.E. is removed and carbon tetrachloride is concentrated on water bath to 0.3～0.5 ml. and all CCl(4) is used for a determination sample. The sample is placed on the paper (Toyo-filter paper No. 50 or 51A) in a thin line at a distance of 3 cm. from the edge, and the spot is developed with a mixture of 20 ml. of CCl(4) and 1 ml. of 90% ethylalcohoI. After development for 30～40 min., an orange-colored linear spot appears at a distance of 9～10 em. from the origin point. Spot intensity is measured at 460 mμ with Natsume's densitometer and quantitative estimation is made comparing with the standard graph. 2. Effects of radioactive thermal spring bathing and internal use of vitriol water upon cobalt levels in blood. As the author's method above-mentioned is able to determine the cobalt level in a small amount of blood, it is very convenient in investigating cobalt metabolism in the field of balneology. The author examined the changes of cobalt levels in blood after radioactive thermal bathing as well as after internal use of acid vitriol water. a. By the author's method cobalt in normal human blood was 0.4～3.6γ/100ml. in man (average: 1.6±0.4γ/100ml.) and 0.2～2.2γ/100ml. in woman (average: 0.7±0.3γ/100ml.). b. The cobalt levels in blood were measured by the author's method before and 5, 30, 60 minutes after the radioactive thermal single bathing, and before and 1, 2, 3, 4 weeks after a series of radioactive thermal baths (Rn-content: 10～30 Mache, 42～3°C., for 10 minutes). The cobalt levels in the blood of healthy subjects showed no significant change after the thermal single bathing, but those of patients with rheumatoid arthritis showed a slight increase on 3rd or 7th day and a fall on 2nd week of a series of radioactive thermal baths and then tended to return to the initial levels during the 3rd and 4th weeks of spa treatment. c. Thirty ml. of Yanahara mineral water (an acid vitriol water, pH: 2.2) was diluted with plain water to 200 ml. (Co(++)content: ca.3γ) and administered to healthy fasting subjects orally. Blood samples were taken from the cubital vein before and 1, 3, 6 hours after the intake of the vitriol water. The cobalt levels in the blood showed an increase of 14% of the initial levels at 1 and 3 hours and a decrease of 22% at 6 hours after the drinking of Yanahara mineral water. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-01 |
| 巻 | 24巻 |
| 開始ページ | 29 |
| 終了ページ | 53 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40250 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532366 |
| JaLCDOI | 10.18926/40247 |
|---|---|
| タイトル（別表記） | Studies on the Influences of Balneal Treatment on Female Sexual Function |
| フルテキストURL | pitsr_025_025_052.pdf |
| 著者 | 長谷川 安正| |
| 抄録 | In the present study, observations of changes on female sexual function by balneal treatment were carried out with female rats with respects to sexual cycle, histological changes in ovary and uterus, histo-chemical changes in pituitary, cholinesterase activity in brain, cholesterol levels in ovary, etc. The results obtained were as follows. 1) Significant changes of sexual cycle appeared in 47 (62%) out of the 76 rats which were treated with several kinds of artificial balneal water at the temperature of 42°C (for 5 minutes per single course of the balneal treatment, twice daily during 4 weeks). Similar changes of sexual cycle also appeared in the subjects which were treated with the same kinds of balneal water at 37°C, though having showed to be less than the changes in case of the balneal treatment at 42°C. 2) A significant tendency of regulating sexual cycle of rat to normal was demonstrated in the subjects which were treated with artificial balneal sulfer, and on the other hand, a significant tendency of disturbing the cycle was demonstrated in the sUbjects which were treated with artificial balneal acid and alkali. 3) A tendency of extending the period of dioesterus phase in sexual cycle of rat was found in the subjects which were treated with our laboratory' balneal water at 42°C for 10 minutes per single course four times daily during 10 days. In these subjects, it was also demonstrated that the period of the estrus phase tended to be prolonged. 4) Histological pictures in ovary and uterus indicated normal growth in the subjects of which the sexual cycles were normalized by balneal treatment, whereas indicated an atrophy in the subjects of which the cycles were disturbed. Significant atrophy tended to appear remarkably in the subjects which developed some irregular cycles due to the treatment with artificial balneal acid or alkali. In view point of the daily changes in these tissues, it was demonstrated that atrophic changes appeared at the 10th day after onset of the treatment with a balneal water at 42°C for 5 minutes per single course or with a balneal water at 37°C for 5 minutes, and then turned to normal pictures at the 20th day after onset of the treatment. It was also indicated that remarkable atrophic changes in ovary and uterus appeared immediately after 10 days treatment with a balneal water at 42°C for 10 minutes per single course four times daily, and then turned to show a slight hyperfunction in the ovary at the 10th day after discontinuation of this balneal treatment. 5) A certain correlation was found between cholinesterase activity in the brain of rat and counts of PAS positive cells in the anterior pituitary (on the sexual zone named by Purves, H. D and W. E. Griesbach). Both the activity and the counts decreased at the 10th day after onset of the balneal treatment at the temperature of 42°C for 5 minutes per single course twice daily, and then increased at the 20th day after onset of this treatment. It was also demonstrated that both the activity and the counts decreased significantly at the 10th day after onset of the balneal treatment at 42°C for 10 minutes per single course four times daily, and then increased remarkably at the 10th day after discontinuation of this treatment. 6) A negative correlation was demonstrated between changes of cholesterol levels in ovary and those of cholinesterase activity in brain. Both the levels and the activity increased transitorily at the 10th day after the balneal treatment at 42°C for 5 minutes per single course, and then decreased at the 20th day after onset of the treatment. It was also demonstrated that both the activity and the levels increased at the 10th day after onset of the treatment at 42°C for 10 minutes per single course four times daily, and then decreased after discontinuation of this treatment. From the results mentioned above the following deduction may be drawn: (a) Sexual function is affected apparently by balneal treatment; (b) As to the mode of action of balneal water on sexual function, it is likely that balneal water acts extensively on autonomic nervous system, followed by producing changes in sexual function. In the other words, it seems that balneal water primarily affects on upper central nervous system, i. e. diencephalo-hypophyseo-system, and secondarily produces changes in sexual gland; (c) It was also demonstrated that though a transitory depression in sexual function appeared individually in some subjects which were treated with extensive stimulative balneal water or over time of balneal treatment, but in even the same subjects hyperfunction often appeared after discontinuation of such a treatment. These evidence should be taken into consideration in case of clinical balneotherapy; (d) In view point that the balneotherapy produces changes in sexual function through acting on central nervous system, it may be suggested that balneotherapy with conventional hormon therapy could produce the most desirous effect for the treatment of fertility and insufficiency of sexual function. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-05 |
| 巻 | 25巻 |
| 開始ページ | 25 |
| 終了ページ | 52 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462888 |
| JaLCDOI | 10.18926/40240 |
|---|---|
| タイトル（別表記） | Clinical Study on the Treatment of Rheumatoid Arthritis Part III. Experiences of Capsulosynovectomia Genu Anterior Totalis for Rheumatoid Arthritis |
| フルテキストURL | 026_020_030.pdf |
| 著者 | 泉 友圀| |
| 抄録 | Capsulosynovectomia genu anterior totalis was performed on five cases had marked hydrops and capsular thickening of joints, in which intraarticular injection of hydrocortisone or prednisolone, balneotherapy and hydrotherapy had been repeated in vain for long period with long standing pain and gradual decrease in motor function. The progress was observed for six to seventeen months after the operation, obtaining following results. Rheumatic symptoms were significantly improved after operation and restortion of function was also valuable. No exacerbations in the other joints and general condition were noted with rather improvement in the sign. Further, these operated joints became to react better, differ from preoperative, to balneotherapy and "Fango" with noticeable effects on the restoration of articular function. In histological findings of the resected synovia four cases showed Rs. and one Fr. by T. Kodama's classification. It is, therefore, recommended to appreciate this kind of operation on the cases shown no effects in the treatment of adrenocortical hormone or hot spring bath, which led to the decrease in gait ability, on the standpoint of medical rehabilitation. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 20 |
| 終了ページ | 30 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40239 |
|---|---|
| タイトル（別表記） | Clinical Study on the Treatment of Rheumatoid Arthritis Part II. Experiences of Intraarticular Injection of Prednisolone for Rheumatoid Arthritis |
| フルテキストURL | 026_008_019.pdf |
| 著者 | 泉 友圀| |
| 抄録 | Meticorterone (Prednisolone acetate) were injected into joints of 33 cases of rheumatoid arthritis, 172 times in total, with better results. Although intraarticular injection of prednisolone is, at present, to be one of the most effective treatment for rheumatoid arthritis, one must pay attention at the appearance of general effect in frequent and abundant injection. Comparative studies were performed on the effects of intraarticular injectons of prednisolone T. B. A, (on twelve cases), hydrocortisone acetate and meticorterone. Prednisolone T. B. A. was proved markedly longer effect in local with minimum general effect, It was, therefore, thought that prednisolone T. B. A. was safest and most effective in intraarticular therapy on the rheumatoid arthritis. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 8 |
| 終了ページ | 19 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |