検索結果 - 岡山大学学術成果リポジトリ

Heterogeneity of the effect of the COVID-19 pandemic on the incidence of Metabolic Syndrome onset at a Japanese campus

フルテキストURL	fulltext.pdf
著者	Mitsuhashi, Toshiharu\|
キーワード	COVID-19 Metabolic syndrome Healch check up Conditional average treatment effect CATE Public health Pandemic
発行日	2024-04-05
出版物タイトル	PeerJ
巻	12巻
出版者	PeerJ
開始ページ	e17013
ISSN	2167-8359
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Mitsuhashi
論文のバージョン	publisher
PubMed ID	38590703
DOI	10.7717/peerj.17013
Web of Science KeyUT	001203244800004
関連URL	isVersionOf https://doi.org/10.7717/peerj.17013

令和４年度岡山医学会賞　胸部・循環研究奨励賞（砂田賞）

タイトル（別表記）	The 2022 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2022 Sunada Prize)
著者	板野純子\|
出版物タイトル	岡山医学会雑誌
発行日	2024-04-01
巻	136巻
号	1号
開始ページ	1
終了ページ	3
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.136.1
言語	日本語
著作権者	Copyright (c) 2024 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.136.1

Dual roles of cellular communication network factor 6 (CCN6) in the invasion and metastasis of oral cancer cells to bone via binding to BMP2 and RANKL

フルテキストURL	fulltext.pdf
著者	Hochi, Hiroaki\| Kubota, Satoshi\| Takigawa, Masaharu\| Nishida, Takashi\|
発行日	2023-08-17
出版物タイトル	Carcinogenesis
巻	44巻
号	8-9号
出版者	Oxford University Press (OUP)
開始ページ	695
終了ページ	707
ISSN	0143-3334
NCID	AA00141799
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37590989
DOI	10.1093/carcin/bgad057
Web of Science KeyUT	001061431500001
関連URL	isVersionOf https://doi.org/10.1093/carcin/bgad057

Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration

フルテキストURL	fulltext.pdf
著者	Murata, Hitoshi\| Phoo, May Tha Zin\| Ochi, Toshiki\| Tomonobu, Nahoko\| Yamamoto, Ken-ichi\| Kinoshita, Rie\| Miyazaki, Ikuko\| Nishibori, Masahiro\| Asanuma, Masato\| Sakaguchi, Masakiyo\|
キーワード	JNK PARK2 Parkinson’sdisease Phosphorylation SARM1
発行日	2023-09-19
出版物タイトル	The Journal of Biochemistry
巻	174巻
号	6号
出版者	Oxford University Press (OUP)
開始ページ	533
終了ページ	548
ISSN	0021-924X
NCID	AA00694073
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37725528
DOI	10.1093/jb/mvad068
Web of Science KeyUT	001079972500001
関連URL	isVersionOf https://doi.org/10.1093/jb/mvad068

Non-enzymatic detection of glucose levels in human blood plasma by a graphene oxide-modified organic transistor sensor

フルテキストURL	fulltext.pdf
著者	Fan, Haonan\| Sasaki, Yui\| Zhou, Qi\| Tang, Wei\| Nishina, Yuta\| Minami, Tsuyoshi\|
発行日	2023
出版物タイトル	Chemical Communications
巻	59巻
号	17号
出版者	Royal Society of Chemistry (RSC)
開始ページ	2425
終了ページ	2428
ISSN	1359-7345
NCID	AA11071130
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2023
論文のバージョン	publisher
PubMed ID	36745444
DOI	10.1039/d2cc07009j
Web of Science KeyUT	000928604600001
関連URL	isVersionOf https://doi.org/10.1039/d2cc07009j

FLOURY ENDOSPERM 6 mutations enhance the sugary phenotype caused by the loss of ISOAMYLASE1 in barley

フルテキストURL	fulltext.pdf
著者	Matsushima, Ryo\| Hisano, Hiroshi\| Galis, Ivan\| Miura, Satoko\| Crofts, Naoko\| Takenaka, Yuto\| Oitome, Naoko F.\| Ishimizu, Takeshi\| Fujita, Naoko\| Sato, Kazuhiro\|
備考	The version of record of this article, first published in Theoretical and Applied Genetics, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00122-023-04339-5\|
発行日	2023-04
出版物タイトル	Theoretical and Applied Genetics
巻	136巻
号	4号
出版者	Springer Science and Business Media LLC
開始ページ	94
ISSN	0040-5752
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37010621
DOI	10.1007/s00122-023-04339-5
Web of Science KeyUT	000962880600001
関連URL	isVersionOf https://doi.org/10.1007/s00122-023-04339-5

Catalytic synthesis and physical properties of CO2-based cross-linked poly(cyclohexene carbonate)s

フルテキストURL	fulltext.pdf
著者	Maeda, Chihiro\| Kawabata, Kenta\| Niki, Kaito\| Sako, Yuma\| Okihara, Takumi\| Ema, Tadashi\|
発行日	2023
出版物タイトル	Polymer Chemistry
巻	14巻
号	37号
出版者	Royal Society of Chemistry (RSC)
開始ページ	4338
終了ページ	4343
ISSN	1759-9954
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2023
論文のバージョン	publisher
DOI	10.1039/d3py00870c
Web of Science KeyUT	001070054600001
関連URL	isVersionOf https://doi.org/10.1039/d3py00870c

How do water-mediated interactions and osmotic second virial coefficients vary with particle size?

フルテキストURL	fulltext.pdf
著者	Naito, Hidefumi\| Sumi, Tomonari\| Koga, Kenichiro\|
発行日	2024
出版物タイトル	Faraday Discussions
巻	249巻
出版者	Royal Society of Chemistry (RSC)
開始ページ	440
終了ページ	452
ISSN	1359-6640
NCID	AA10836538
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2024
論文のバージョン	publisher
PubMed ID	37791511
DOI	10.1039/d3fd00104k
Web of Science KeyUT	001077081700001
関連URL	isVersionOf https://doi.org/10.1039/d3fd00104k

Complete genomic sequence of Vibrio fluvialis strain IDH5335 isolated from a patient with diarrhea in Kolkata, India

フルテキストURL	fulltext.pdf
著者	Chowdhury, Goutam\| Kitahara, Kei\| Taniguchi, Makoto\| Uesaka, Kazuma\| Muzembo, Basilua Andre\| Mitra, Debmalya\| Ohno, Ayumu\| Ramamurthy, Thandavarayan\| Dutta, Shanta\| Miyoshi, Shin-ichi\| Mukhopadhyay, Asish Kumar\|
キーワード	Vibrio fluvialis diarrhea bacteria genome
発行日	2023-12-14
出版物タイトル	Microbiology Resource Announcements
巻	12巻
号	12号
出版者	American Society for Microbiology
ISSN	2576-098X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	Copyright © 2023 Chowdhury et al.
論文のバージョン	publisher
PubMed ID	37943041
DOI	10.1128/mra.00707-23
Web of Science KeyUT	001102333600001
関連URL	isVersionOf https://doi.org/10.1128/mra.00707-23

Flavobacterium okayamense sp. nov. isolated from surface seawater

フルテキストURL	fulltext.pdf
著者	Kitahara, Kei\| Muzembo, Basilua Andre\| Morohoshi, Sho\| Kunihiro, Tadao\| Tazato, Nozomi\| Ohno, Ayumu\| Uesaka, Kazuma\| Taniguchi, Makoto\| Miyoshi, Shin-ichi\|
キーワード	Bacteroidota Flavobacterium New taxa Sea water
備考	The version of record of this article, first published in Archives of Microbiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00203-023-03682-x\|
発行日	2023-09-29
出版物タイトル	Archives of Microbiology
巻	205巻
号	10号
出版者	Springer Science and Business Media LLC
開始ページ	346
ISSN	0302-8933
NCID	AA00548209
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37773547
DOI	10.1007/s00203-023-03682-x
Web of Science KeyUT	001075306500001
関連URL	isVersionOf https://doi.org/10.1007/s00203-023-03682-x

Recent advances in CGG repeat diseases and a proposal of fragile X-associated tremor/ataxia syndrome, neuronal intranuclear inclusion disease, and oculophryngodistal myopathy (FNOP) spectrum disorder

フルテキストURL	fulltext.pdf
著者	Ishiura, Hiroyuki\| Tsuji, Shoji\| Toda, Tatsushi\|
備考	The version of record of this article, first published in Journal of Human Genetics, is available online at Publisher’s website: http://dx.doi.org/10.1038/s10038-022-01116-y\|
発行日	2023-01-20
出版物タイトル	Journal of Human Genetics
巻	68巻
号	3号
出版者	Springer Science and Business Media LLC
開始ページ	169
終了ページ	174
ISSN	1434-5161
NCID	AA11206160
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	36670296
DOI	10.1038/s10038-022-01116-y
Web of Science KeyUT	000916021000001
関連URL	isVersionOf https://doi.org/10.1038/s10038-022-01116-y

CDK4/6 signaling attenuates the effect of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

フルテキストURL	fulltext.pdf
著者	Hara, Naofumi\| Ichihara, Eiki\| Kano, Hirohisa\| Ando, Chihiro\| Morita, Ayako\| Nishi, Tatsuya\| Okawa, Sachi\| Nakasuka, Takamasa\| Hirabae, Atsuko\| Abe, Masaya\| Asada, Noboru\| Ninomiya, Kiichiro\| Makimoto, Go\| Fujii, Masanori\| Kubo, Toshio\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
キーワード	Epidermal growth factor receptor (EGFR) non-small cell lung cancer (NSCLC) cell cycle CDK4/6 inhibitor
発行日	2023-10-31
出版物タイトル	Translational Lung Cancer Research
巻	12巻
号	10号
出版者	AME Publishing Company
ISSN	2218-6751
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Translational Lung Cancer Research.
論文のバージョン	publisher
PubMed ID	38025818
DOI	10.21037/tlcr-23-99
Web of Science KeyUT	001091030600001
関連URL	isVersionOf https://doi.org/10.21037/tlcr-23-99

A Case of Gallbladder Cancer with Trousseau Syndrome Successfully Treated Using Radical Resection

JaLCDOI	10.18926/AMO/66931
フルテキストURL	78_2_201.pdf
著者	Masunaga, Akari\| Tabuchi, Motoyasu\| Sakamoto, Shinya\| Yoshimatsu, Rika\| Matsumoto, Manabu\| Iwata, Jun\| Okabayashi, Takehiro\|
抄録	Trousseau syndrome is characterized by cancer-associated systemic thrombosis. We describe the first case of a successfully treated gallbladder adenocarcinoma accompanied by Trousseau syndrome. A 66-year-old woman presented with right hemiplegia. Magnetic resonance imaging identified multiple cerebral infarctions. Her serum carbohydrate antigen 19-9 and D-dimer levels were markedly elevated, and a gallbladder tumor was detected via abdominal computed tomography. Venous ultrasonography of the lower limbs revealed a deep venous thrombus in the right peroneal vein. These findings suggested that the brain infarctions were likely caused by Trousseau syndrome associated with her gallbladder cancer. Radical resection of the gallbladder tumor was performed. The resected gallbladder was filled with mucus and was pathologically diagnosed as an adenocarcinoma. Her postoperative course was uneventful, and she received a one-year course of adjuvant therapy with oral S-1. No cancer recurrence or thrombosis was noted 26 months postoperatively. Despite concurrent Trousseau syndrome, a radical cure of the primary tumor and thrombosis could be achieved with the appropriate treatment.
キーワード	gallbladder cancer Trousseau syndrome radical surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	201
終了ページ	204
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688839
Web of Science KeyUT	001227932200001

Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study

JaLCDOI	10.18926/AMO/66927
フルテキストURL	78_2_185.pdf
著者	Takahashi, Hiroko\| Eguchi, Jun\| Watanabe, Mayu\| Nakayama, Masanori\| Wada, Jun\|
抄録	The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients.
キーワード	obesity type 2 diabetes COVID-19 vaccination
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	185
終了ページ	191
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688836
Web of Science KeyUT	001227932200002

The Relationships among Internalized Stigma, Sense of Coherence, and Personal Recovery of Persons with Schizophrenia Living in the Community

JaLCDOI	10.18926/AMO/66926
フルテキストURL	78_2_171.pdf
著者	Kuramoto, Aya\| Saito, Shinya\| Watanabe, Kumi\|
抄録	We investigated (i) the relationships among internalized stigma (IS), sense of coherence (SOC), and the personal recovery (PR) of persons with schizophrenia living in the community, and (ii) how to improve the support for these individuals. A questionnaire survey on IS, SOC, and PR was sent by mail to 270 persons with schizophrenia living in the community who were using psychiatric daycare services, of whom 149 responded and 140 were included in the analysis. We established a hypothetical model in which IS influences PR, and SOC influences IS and PR, and we used structural equation modeling to examine the relationships among these concepts. The goodness of fit was acceptable. Our findings suggest that rather than directly promoting PR, SOC promotes PR by mitigating the impact of IS. It is important for nurses/supporters to support individuals with schizophrenia living in the community so that they have opportunities to reflect on their own experiences through their activities and to share their experiences with peers. Nurses/supporters themselves should also reflect on their own support needs. Our findings suggest that this will lead to a reduction of IS and the improvement of SOC, which will in turn promote personal recovery.
キーワード	schizophrenia internalized stigma sense of coherence personal recovery community
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	171
終了ページ	184
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688835
Web of Science KeyUT	001229151800009

The Impact of Light Touch and Pin Prick on Functional Outcomes in Patients with Traumatic Spinal Cord Injury

JaLCDOI	10.18926/AMO/66925
フルテキストURL	78_2_163.pdf
著者	Deguchi, Takayuki\| Kanda, Kanae\| Furusawa, Kazunari\| Nlandu Roger Ngatu\| Hirao, Tomohiro\|
抄録	A spinal cord injury (SCI) can cause severe lifelong functional disability and profoundly affect an individual’s daily life. We investigated the prediction of patients’ post-SCI functional outcomes by evaluating sensory scores rather than motor scores, as the latter’s association with functional outcomes is well established. We examined patients’ responses to a light touch (LT) and pin prick (PP) at admission and the response data’s usefulness as predictors of functional outcomes (i.e., ability to perform activities of daily living) at discharge. This exploratory observational study used data from the Japanese National Spinal Cord Injury Database (SCI-J). Data from 3,676 patients who met the inclusion criteria and were admitted for an SCI between 1997 and 2020 were analyzed. The motor score of the Functional Independence Measure (mFIM) at discharge was used as an index of functional outcome. A multiple regression analysis revealed that the mFIM was associated with both the LT response (β=0.07 (0.01), p<0.001) and the PP response (β=0.07 (0.01), p<0.001) at admission. The false discovery rate log-worth values for LT and PP were 6.6 and 8.5, respectively. Our findings demonstrate that LT and PP scores at admission can help predict patients’ functional outcomes after an SCI, although the magnitude of their contributions is not high.
キーワード	functional independence measure light touch pin prick spinal cord injury Japanese National Spinal Cord Injury Database
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	163
終了ページ	170
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688834
Web of Science KeyUT	001229151800008

p53-Armed Oncolytic Virotherapy Improves Radiosensitivity in Soft-Tissue Sarcoma by Suppressing BCL-xL Expression

JaLCDOI	10.18926/AMO/66924
フルテキストURL	78_2_151.pdf
著者	Komatsubara, Tadashi\| Tazawa, Hiroshi\| Hasei, Joe\| Omori, Toshinori\| Sugiu, Kazuhisa\| Mochizuki, Yusuke\| Demiya, Koji\| Yoshida, Aki\| Fujiwara, Tomohiro\| Kunisada, Toshiyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
抄録	Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
キーワード	soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	151
終了ページ	161
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688833
Web of Science KeyUT	001229151800007

Impact of Travel Distance on Surgical Outcomes of Patients Surgically Treated for Non-Small Cell Lung Cancer: A Single-Center Study in Ehime, Japan

JaLCDOI	10.18926/AMO/66923
フルテキストURL	78_2_143.pdf
著者	Shigematsu, Hisayuki\| Yamashita, Natsumi\| Suehisa, Hiroshi\| Ueno, Tsuyoshi\| Ryuko, Tsuyoshi\| Sugihara, Takahito\| Nakashima, Shohei\| Sano, Yoshifumi\| Yamashita, Motohiro\|
抄録	Travel burden is a poor prognostic factor for many cancers worldwide because it hinders optimal diagnosis and treatment planning. Currently, the impact of travel burden on survival after surgery for non-small cell lung cancer (NSCLC) in Japan is largely unexplored. We examined the impact of travel distance on the postoperative outcomes of patients with NSCLC in Ehime Prefecture, Japan. The data of 1212 patients who underwent surgical resection for NSCLC were retrospectively reviewed. Patients were divided into quartiles based on the travel distance from their home to the hospital (≤ 13 km, 13-40 km, 40-57 km, and > 57 km) in Ehime Prefecture. We found no significant differences among the quartiles in baseline clinicopathological characteristics, including sex, smoking status, histology, surgical procedure, clinical stage, and pathological stage. Overall survival (OS) and relapse-free survival (RFS) also were not significantly different among the travel distance quartiles. We conclude that travel distance did not impact OS or RFS among patients with NSCLC who underwent surgical resection at our institution.
キーワード	non-small cell lung cancer travel distance travel burden lung surgery surgical outcome
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	143
終了ページ	149
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688832
Web of Science KeyUT	001229151800006

Artificial intelligence to detect noise events in remote monitoring data

フルテキストURL	fulltext.pdf
著者	Nishii, Nobuhiro\| Baba, Kensuke\| Morooka, Ken'Ichi\| Shirae, Haruto\| Mizuno, Tomofumi\| Masuda, Takuro\| Ueoka, Akira\| Asada, Saori\| Miyamoto, Masakazu\| Ejiri, Kentaro\| Kawada, Satoshi\| Nakagawa, Koji\| Nakamura, Kazufumi\| Morita, Hiroshi\| Yuasa, Shinsuke\|
キーワード	artificial intelligence five-fold cross-validation intracardiac electrogram noise event remote monitoring
発行日	2024-04-11
出版物タイトル	Journal of Arrhythmia
巻	40巻
号	3号
出版者	Wiley
開始ページ	560
終了ページ	577
ISSN	1880-4276
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Authors.
論文のバージョン	publisher
PubMed ID	38939795
DOI	10.1002/joa3.13037
Web of Science KeyUT	001200108800001
関連URL	isVersionOf https://doi.org/10.1002/joa3.13037

Photon-Counting Detector CT: Potential for 75% Reduction in Contrast Medium Amount: A Phantom Study

JaLCDOI	10.18926/AMO/66916
フルテキストURL	78_2_135.pdf
著者	Higaki, Fumiyo\| Morimitsu, Yusuke\| Iguchi, Toshihiro\| Saito, Hayato\| Takaki, Haruhiko\| Nakagoshi, Ayako\| Wada, Maki\| Uka, Mayu\| Akagi, Noriaki\| Mitsuhashi, Toshiharu\| Matsui, Yusuke\| Hiraki, Takao\|
抄録	This study aimed to evaluate the potential reduction in contrast medium utilization using photon-counting detector computed tomography (PCD-CT). One PCD-CT scan (CT1) and three conventional (non-PCD-CT) CT scans (CT2-CT4) were performed using a multi-energy CT phantom that contained eight rods with different iodine concentrations (0.2, 0.5, 1, 2, 5, 10, 15, and 20 mg/ml). The CT values of the seven groups (CT1 for 40, 50, 60, and 70 keV; and CT2-4) were measured. Noise and contrast-to-noise ratio (CNR) were assessed for the eight rods at various iodine concentrations. CT2 and CT1 (40 keV) respectively required 20 mg/ml and 5 mg/ml of iodine, indicating that a comparable contrast effect could be obtained with approximately one-fourth of the contrast medium amount. The standard deviation values increased at lower energy levels irrespective of the iodine concentration. The CNR exhibited a decreasing trend with lower iodine concentrations, while it remained relatively stable across all iodine levels (40-70 keV). This study demonstrated that virtual monochromatic 40 keV images offer a similar contrast effect with a reduced contrast medium amount when compared to conventional CT systems at 120 kV.
キーワード	photon-counting detector CT energy integrating detector CT computed tomography contrast medium amount reduction
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	135
終了ページ	142
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688831
Web of Science KeyUT	001229151800005