著者 平尾 謙| 河本 博文| 山本 和秀|
発行日 2009-12-01
出版物タイトル 岡山医学会雑誌
121巻
3号
資料タイプ 学術雑誌論文
著者 岡 隆彦| 友田 純| 小橋 春彦| 坂井 宣行| 坂口 孝作| 山本 和秀| 東 俊宏| 伊藤 俊雄| 山田 剛太郎| 辻 孝夫|
発行日 1994
出版物タイトル 岡山医学会雑誌
106巻
5-6号
資料タイプ 学術雑誌論文
著者 藤井 雅邦| 河本 博文| 山本 和秀|
発行日 2010-12-01
出版物タイトル 岡山医学会雑誌
122巻
3号
資料タイプ 学術雑誌論文
著者 井上 雅文| 岡田 裕之| 河原 祥朗| 川野 誠司| 山本 和秀|
発行日 2009-08-03
出版物タイトル 岡山医学会雑誌
121巻
2号
資料タイプ 学術雑誌論文
著者 山本 和秀|
発行日 2008-12-01
出版物タイトル 岡山医学会雑誌
120巻
3号
資料タイプ 学術雑誌論文
著者 小林 功幸| 中村 進一郎| 大西 秀樹| 歳森 淳一| 桑木 健志| 萩原 宏明| 三宅 康広| 白羽 英則| 能祖 一裕| 八木 孝仁| 田中 紀章| 山本 和秀|
発行日 2009-04-01
出版物タイトル 岡山医学会雑誌
121巻
1号
資料タイプ 学術雑誌論文
タイトル(別表記) Fermented persimmon extract (kaki-shibu) is useful as a standard for component analyses of persimmon phytobezoars
フルテキストURL 126_127.pdf
著者 岩室 雅也| 岡本 裕子| 村田 年弘| 河合 良成| 白羽 英則| 岡田 裕之| 山本 和秀|
抄録 The definite diagnosis of persimmon phytobezoar (i.e., diospyrobezoar) is often accomplished by a component analysis using infrared spectroscopy. However, no studies have been conducted to investigate which substance is the best as a standard for the component analysis. Here we analyzed tannic acid, Japanese persimmon (kaki), fermented persimmon extract (kaki-shibu), conventional dried persimmon, and dried persimmon smoked in sulfur (ampo-kaki) by infrared spectroscopy to determine which would be optimal as a component analysis standard. The spectrum between 1,600 to 600cm-1 of a persimmon phytobezoar was quite similar to the spectrum of kaki-shibu rather than that of tannic acid. Consequently, we conclude that kaki-shibu should be used as a standard for infrared spectroscopy analyses of persimmon phytobezoars.
キーワード 柿胃石(gastric phytobezoar) タンニン酸(tannic acid) 消化管異物(gastrointestinal foreign body) 成分分析(component analysis)
出版物タイトル 岡山医学会雑誌
発行日 2014-08-01
126巻
2号
開始ページ 127
終了ページ 131
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.127
NAID 130004685263
著者 川野 誠司| 岡田 裕之| 河原 祥朗| 井上 雅文| 山本 和秀|
発行日 2009-08-03
出版物タイトル 岡山医学会雑誌
121巻
2号
資料タイプ 学術雑誌論文
著者 福田 哲也| 山田 剛太郎| 小川 裕道| 奥新 浩晃| 兵頭 一之介| 西原 隆| 水野 元夫| 坂本 裕治| 長島 秀夫| 山本 和秀| 小林 敏成| 吉田 智郎|
発行日 1984-04-30
出版物タイトル 岡山医学会雑誌
96巻
3-4号
資料タイプ 学術雑誌論文
著者 小川 恒由| 河本 博文| 山本 和秀|
発行日 2009-12-01
出版物タイトル 岡山医学会雑誌
121巻
3号
資料タイプ 学術雑誌論文
著者 堤 康一郎| 河本 博文| 山本 和秀|
発行日 2010-12-01
出版物タイトル 岡山医学会雑誌
122巻
3号
資料タイプ 学術雑誌論文
著者 半井 明日香| 加藤 順| 平岡 佐規子| 栗山 宗彰| 井口 俊博| 竹井 大介| 森藤 由記| 秋田 光洋| 高橋 索真| 原田 馨太| 岡田 裕之| 山本 和秀|
発行日 2013-12-02
出版物タイトル 岡山医学会雑誌
125巻
3号
資料タイプ 学術雑誌論文
著者 Asagi, Akinori| Ohta, Koji| Nasu, Junichirou| Tanada, Minoru| Nadano, Seijin| Nishimura, Rieko| Teramoto, Norihiro| Yamamoto, Kazuhide| Inoue, Takeshi| Iguchi, Haruo|
発行日 2013-01
出版物タイトル Pancreas
42巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/45269
フルテキストURL 65_2_105.pdf
著者 Tsuzuki, Takao| Okada, Hiroyuki| Nasu, Junichiro| Takenaka, Ryuta| Inoue, Masafumi| Kawano, Seiji| Kita, Masahide| Hori, Keisuke| Yamamoto, Kazuhide|
抄録 The objectives of this study were to evaluate the accuracy of endoscopic ultrasonography (EUS) in local and regional staging of early gastric cancer, to analyze the factors influencing the accuracy of EUS, and to reveal the usefulness and problems of EUS in pre-treatment staging of gastric cancer. We examined 105 lesions in 104 patients with histologically confirmed gastric cancer and retrospectively evaluated them with EUS. The diagnostic accuracy, sensitivity, and specificity of EUS were determined by comparing the pre-treatment EUS with the postoperative histopathological findings. The overall diagnostic accuracy of EUS for the depth of cancer invasion was 86%. The overall sensitivity and specificity were 60% and 96%, respectively. The accuracy significantly declined in lesions located in the upper-third of the stomach (70%). Type 0-I lesions tended to be over-staged (12&), and the upper-third lesions tended to be under-staged (23%). The accuracy significantly declined in differentiated adenocarcinoma with massive submucosal invasion (56.5%). EUS is useful for evaluating the depth of gastric cancer invasion which determines the feasibility of endoscopic treatment. However, it is noteworthy that the diagnostic accuracy of the invasion depth diminished for lesions in the upper third of the stomach.
キーワード endoscopic ultrasonography early gastric cancer accuracy sensitivity specificity
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-04
65巻
2号
出版者 Okayama University Medical School
開始ページ 105
終了ページ 112
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21519368
Web of Science KeyUT 000289818800006
JaLCDOI 10.18926/AMO/53026
フルテキストURL 68_6_369.pdf
著者 Iwamuro, Masaya| Miyashima, Yuichi| Yoshioka, Takahiro| Murata, Toshihiro| Miyabe, Yoshio| Kawai, Yoshinari| Urata, Haruo| Shiraha, Hidenori| Okada, Hiroyuki| Yamamoto, Kazuhide|
抄録 A 67-year-old Japanese man underwent enterotomy because of enterolith ileus. Component analysis by infrared spectroscopy revealed that the enterolith was composed of a high concentration of deoxycholic acid. We further analyzed and compared the ultrastructure of the enterolith and a commercially available powdered form of deoxycholic acid by means of scanning electron microscopy and energy dispersive X-ray spectroscopy. Energy dispersive X-ray spectroscopy analysis revealed that the ratios of carbon and oxygen in the enterolith were equal to those in the deoxycholic acid powder. Scanning electron microscopy analysis showed rectangular prism-shaped particles on the surface of the enterolith. This structure was similar to that of the deoxycholic acid powder. The surgically removed enterolith had a twisted and coiled appearance. Possible mechanisms underlying the formation of this unique form are discussed.
キーワード enterolith deoxycholic acid scanning electron microscopy infrared spectroscopy energy dispersive X-ray spectroscopy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-12
68巻
6号
出版者 Okayama University Medical School
開始ページ 369
終了ページ 374
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25519031
Web of Science KeyUT 000346882200007
著者 Matsuo, Noriyuki| Shiraha, Hidenori| Fujikawa, Tatsuya| Takaoka, Nobuyuki| Ueda, Naoki| Tanaka, Shigetomi| Nishina, Shinichi| Nakanishi, Yutaka| Uemura, Masayuki| Takaki, Akinobu| Nakamura, Shinichiro| Kobayashi, Yoshiyuki| Nouso, Kazuhiro| Yagi, Takahito| Yamamoto, Kazuhide|
発行日 2009-07-18
出版物タイトル BMC Cancer
9巻
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/31029
フルテキストURL fulltext.pdf
著者 Makino, Yasuhiro| Yamamoto, Kazuhide| Tsuji, Takao|
抄録

The three-dimensional arrangement of ductular structures formed by oval cells in rats fed 2-acetylaminofluorene (2-AAF) was studied by scanning electron microscopy (SEM) of biliary tract casts and light microscopy of sections of liver injected with india ink via the biliary tract. Both resin and india ink were well injected up to bile ductules, and the findings of each method correlated with each other. By the second week after 2-AAF administration, a few oval cells appeared in the periportal areas forming ductular structures which connected with the portal bile ducts. At the 4th week, increased ductular structures occupied two thirds of the lobule and formed networks communicating with each other, and with the portal bile ducts. At the 8th week, such ductular structures were compressed around hyperplastic nodules and appeared like a basket in biliary casts examined by SEM. Although a histochemical study of gamma-glutamyl transpeptidase revealed activity both on the luminal side of the ductular structures and hepatocytes in hyperplastic nodules, no transition was observed between these two cell populations. These results suggest that oval cells have characteristics more similar to those of biliary epithelia than of hepatocytes, and have no relation to the development of hyperplastic nodules.

キーワード oval cells biliary tract casts scanning electron microscopy hyperplastic nodules hepatocarcinogenesis
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1988-06
42巻
3号
出版者 Okayama University Medical School
開始ページ 143
終了ページ 150
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 2899946
Web of Science KeyUT A1988P034000004
著者 Takeuchi, Yasuto| Ikeda, Fusao| Moritou, Yuki| Hagihara, Hiroaki| Yasunaka, Tetsuya| Kuwaki, Kenji| Miyake, Yasuhiro| Ohnishi, Hideki| Nakamura, Shinichiro| Shiraha, Hidenori| Takaki, Akinobu| Iwasaki, Yoshiaki| Nouso, Kazuhiro| Yamamoto, Kazuhide|
発行日 2013-03
出版物タイトル Journal of Gastroenterology
48巻
3号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/49667
フルテキストURL 67_2_93.pdf
著者 Kita, Masahide| Yokota, Kenji| Okada, Hiroyuki| Take, Susumu| Takenaka, Ryuta| Kawahara, Yoshiro| Oguma, Keiji| Matsushita, Osamu| Yamamoto, Kazuhide|
抄録 Atrophy of the gastric mucosa is a precursor of intestinal-type gastric cancer, and Helicobacter pylori infection causes atrophic gastritis. The aim of this study was to determine whether the genetic diversity of H. pylori virulence genes is associated with the development and progression of gastric atrophy in humans. We isolated and cultured H. pylori strains from patients with gastric ulcer and duodenal ulcer accompanied by atrophic gastritis in background mucosa. H. pylori strains were stored at -80℃ prior to the experiments being carried out. We analyzed iceA, babA, vacA, cagA, and cagE genes by PCR. The cagA gene was analyzed through sequencing of the C-terminal region containing the EPIYA motif, which is related to tyrosine phosphorylation. Severe atrophy was observed in patients with gastric ulcer. The major phenotype of the vacA gene was s1c/m1 (93オ). The cagA gene was detected in all strains. The cagE gene was not detected in 2 and 5 strains from the mild cases and severe cases, respectively. The major cagA EPIYA motif, which is amino acids repeat in the C terminus, was the A-B-D type (44 of 58 strains). The virulence genes were not statistically associated with the severity of atrophy in the background gastric mucosa in humans. Not only identification of bacterial virulence factors but also studies of the host response will be necessary to investigate the progression of gastric atrophy and subsequent cancer development in humans.
キーワード Helicobacter pylori virulence genes chronic atrophic gastritis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-04
67巻
2号
出版者 Okayama University Medical School
開始ページ 93
終了ページ 98
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23603925
Web of Science KeyUT 000317801700003
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/52508