ID | 18252 |
Eprint ID | 18252
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フルテキストURL | |
タイトル(別表記) | Studies on Treatment of Wakana Disease Ⅲ. Etiology of the Iung symptoms of Wakana disease
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著者 |
山本 矩朗
岡山大学医学部平木内科
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抄録 | 1. Mice infected with Anchylostoma caninum larvae labeled with Fe(59) showed anincrease of both radioactivity and the number of the larvae in the lungs 12 hours after the infection. 2. Mice orally infected with Anchylostoma caninum larvae were treated beginning 24 hours after the infection with chloroquine diphosphate, Stibnal and Mapharsen. Chloroquine diphosphate showed a marked anchylostomocidal effect against the larvae migrated into the mouse lungs. Stibnal and Mapharsen were also fairly effective. 3. On the basis of the in vitro anchylostomocidal effect, clinical trial and animal experiment using mice, it is believed that these drugs severely damage hookworm larvae, especially those in the lungs, and the etiology of the lung symptoms of Wakana disease can be largely accounted for by the mechanical irritation of the larvae, although it is probable that they have something to do with an allergic phenomenon.
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発行日 | 1964-03-30
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 76巻
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号 | 1-3号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 161
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終了ページ | 167
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/76/1-3/76_1-3_161/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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