result 14475 件
| FullText URL | K0005190_abstract_review.pdf K0005190_fulltext.pdf |
|---|---|
| Author | Seita, Masayuki| |
| Published Date | 2015-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5190号 |
| Granted Date | 2015-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005189_abstract_review.pdf K0005189_fulltext.pdf |
|---|---|
| Author | Yumoto, Tetsuya| |
| Published Date | 2015-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5189号 |
| Granted Date | 2015-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005188_abstract_review.pdf K0005188_summary.pdf K0005188_fulltext.pdf |
|---|---|
| Author | Narazaki, Shinji| |
| Published Date | 2015-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5188号 |
| Granted Date | 2015-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005187_abstract_review.pdf K0005187_fulltext.pdf |
|---|---|
| Author | Noma, Yasuhiro| |
| Published Date | 2015-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5187号 |
| Granted Date | 2015-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005186_abstract_review.pdf K0005186_fulltext.pdf |
|---|---|
| Author | Toshimori, Junichi| |
| Published Date | 2015-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5186号 |
| Granted Date | 2015-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| JaLCDOI | 10.18926/bgeou/53568 |
|---|---|
| FullText URL | bgeou_159_031_041.pdf |
| Author | Sanada, Satoshi| Takahashi, Ayaka| Diez, Higa Midory| Kageyama, Mizuho| |
| Abstract | Congenital anomalies exert significant impact on individuals and their families, with particularly negative effects on their quality of life. However, studies focusing on the psychological and behavioral characteristics of children with congenital anomalies are still limited, though this information is indispensable for the educational support of such children. In this paper, we reviewed articles dealing with psychological, behavioral and socioemotional characteristics of children with congenital anomalies including Turner syndrome, Klinefelter (XXY) syndrome, XYY syndrome, Apert syndrome, Prader-Willi syndrome, Rubinstein-Taybi syndrome, Williams syndrome, Marfan syndrome, fetal alcohol syndrome, and congenital rubella syndrome. Educational support for these children is also discussed. |
| Keywords | Congenital malformation syndromes chromosomal anomalies congenital contiguous gene syndrome characteristics educational support |
| Publication Title | 岡山大学大学院教育学研究科研究集録 |
| Published Date | 2015-07-28 |
| Volume | volume159 |
| Start Page | 31 |
| End Page | 41 |
| ISSN | 1883-2423 |
| language | English |
| File Version | publisher |
| NAID | 120005649252 |
| JaLCDOI | 10.18926/AMO/53562 |
|---|---|
| FullText URL | 69_4_255.pdf |
| Author | Miyahara, Hiroyuki| Maruyama, Hidehiko| Kanazawa, Akane| Iwasaki, Yuka| Shigemitsu, Yusuke| Watanabe, Hirokazu| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi| |
| Abstract | Since the introduction of the seven-valent pneumococcal conjugate vaccine (PCV7) in 2007, invasive pneumococcal disease has declined, but the incidence of Streptococcus pneumoniae serotype 19A has risen worldwide. The present study examined changes in the features of invasive pneumococcal disease since the introduction of the PCV7 in Kochi, Japan. Pediatric cases of invasive pneumococcal disease were investigated before and after vaccine introduction (January 2008 to December 2013). Cases of invasive pneumococcal disease tended to decrease after PCV7 introduction. In addition, before introduction of the vaccine, most serotypes causing invasive pneumococcal disease were those included in the vaccine. However, after the introduction, we found cases infected by serotypes not covered by vaccine. Penicillin-resistant S. pneumoniae was the predominant serotype causing invasive pneumococcal disease before introduction of the PCV7, and the susceptibility of this serotype to antibiotics improved after vaccine introduction. Serotype isolates identified after vaccine introduction were also relatively susceptible to antibiotic therapy, but decreased susceptibility is expected. |
| Keywords | seven-valent pneumococcal conjugate vaccine (PCV7) invasive pneumococcal disease (IPD) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 260 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289917 |
| Web of Science KeyUT | 000365519100009 |
| JaLCDOI | 10.18926/AMO/53561 |
|---|---|
| FullText URL | 69_4_245.pdf |
| Author | Aoki, Kana| Sakuma, Mayumi| Ogisho, Noriyuki| Nakamura, Kozo| Chosa, Etsuo| Endo, Naoto| |
| Abstract | Exercise is essential for maintaining quality of life (QOL) in elderly individuals. However, adherence to exercise programs is low. Here, we assessed the effectiveness of a self-directed home exercise program with serial telephone contacts to encourage exercise adherence among elderly individuals at high risk of locomotor dysfunction. We recruited community-dwelling adults (ｧ65 years) in Niigata, Japan, who were targets of the long-term care prevention project for locomotor dysfunction but did not participate in the government-sponsored prevention programs. The study was conducted from November 2011 to October 2012. Participants received exercise instruction and performed exercises independently for 3 months with serial telephone contacts. The single-leg stance and five-times sit-to-stand tests were used to assess physical function. The SF-8 was used to measure health-related QOL. Ninety-seven participants were enrolled in the study, representing 2.5ｵ of eligible people;87 completed the intervention. Scores from physical function tests were significantly improved by the intervention, as were 7 of eight SF-8 subscales. Adherence was 85.4ｵ for the single-leg standing exercise and 82.1ｵ for squatting. Thus, self-directed home exercise with serial telephone contacts improved physical function and health-related QOL, representing a promising model for preventing the need for long-term care due to locomotor dysfunction. |
| Keywords | locomotor dysfunction self-home exercise single-leg stance test five-times sit-to-stand test SF-8 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 245 |
| End Page | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289916 |
| Web of Science KeyUT | 000365519100008 |
| JaLCDOI | 10.18926/AMO/53560 |
|---|---|
| FullText URL | 69_4_237.pdf |
| Author | Nanba, Shintarou| Ikeda, Fusao| Fujioka, Shin-ichi| Araki, Yasuyuki| Takaguchi, Kouichi| Hashimoto, Noriaki| Seki, Hiroyuki| Takaki, Akinobu| Iwasaki, Yoshiaki| Yamamoto, Kazuhide| |
| Abstract | The effectiveness of extending treatment duration as response guided therapy was previously reported for chronic hepatitis C (CHC) genotype 1, but is still controversial for genotype 2. The present study is a retrospective cohort study to investigate the effectiveness of extending treatment duration in therapy with pegylated interferon and ribavirin for patients with CHC genotype 2 by focusing on the timing at which patients obtained undetectable HCV RNA. A total of 306 patients who obtained undetectable HCV RNA by week 24 of treatment and completed 24 weeks of treatment were enrolled. Rapid virological response (RVR) to standard therapy was achieved by 122 patients (51ｵ), and 89ｵ of them obtained sustained virological response (SVR), while 69ｵ of non-RVR patients achieved SVR. Non-RVR patients with undetectable HCV RNA at week 8, and insufficient adherence＜80ｵ pegylated interferon and ribavirin during the first 24 weeks, significantly improved their SVR rate by extended therapy. Among patients receiving extended therapy, drug adherences did not differ between SVR and non-SVR patients, indicating that extending treatment duration might compensate for insufficient antiviral effects due to insufficient drug adherences. This finding might be useful in creating a guideline for extending treatment duration for patients with CHC genotype 2. |
| Keywords | hepatitis C virus interferon genotype 2 response-guided therapy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 237 |
| End Page | 244 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289915 |
| Web of Science KeyUT | 000365519100007 |
| JaLCDOI | 10.18926/AMO/53559 |
|---|---|
| FullText URL | 69_4_227.pdf |
| Author | Nakagawa, Naohisa| Koda, Hiromi| Nitta, Noriko| Nakahara, Yukie| Uno, Jiro| Hashimoto, Toru| Nakahori, Takashi| Hasegawa, Masaaki| Kataoka, Mikio| |
| Abstract | Previous reports have shown that some ovarian endometrioid adenocarcinomas and ovarian clear cell adenocarcinomas derive from ovarian endometriosis (OE), and that endocervical-like mucinous borderline ovarian tumors are associated with OE. We examined the relationship between the staging and histological subtypes of OE or epithelial ovarian tumors (EOT) and the serum levels of carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 125 (CA125) to evaluate the potential of these markers for preoperative diagnosis. First, we analyzed the preoperative serum levels of CA19-9 and CA125 in 195 patients who were histopathologically diagnosed with OE or EOT. We then performed a case-control study in which 308 women were enrolled, the 195 women described above and 113 healthy women as control subjects. Serum CA19-9 and CA125 levels were found to be useful in differentiating between OE and serous adenocarcinoma, but not between OE and other EOT. Moreover, serum CA19-9 levels were useful for preoperative assessment between OE and stage I mucinous borderline ovarian tumors, with or without the interstitial infiltration. In addition, considering that the serum CA19-9 levels in stage I mucinous borderline ovarian tumors were elevated via the interstitial infiltration of leukocytes and that precancerous lesions are associated with a cancerous glycosylation disorder in the process of inflammatory carcinogenesis, the CA19-9 level may be considered a suitable biomarker for estimating drug susceptibility. |
| Keywords | ovarian endometriosis epithelial ovarian tumors histological subtype carbohydrate antigen 19-9 carbohydrate antigen 125 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 227 |
| End Page | 235 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289914 |
| Web of Science KeyUT | 000365519100006 |
| JaLCDOI | 10.18926/AMO/53558 |
|---|---|
| FullText URL | 69_4_219.pdf |
| Author | Toshimori, Junichi| Nouso, Kazuhiro| Nakamura, Shinichiro| Wada, Nozomu| Morimoto, Yuki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Kuwaki, Kenji| Ohnishi, Hideki| Ikeda, Fusao| Shiraha, Hidenori| Takaki, Akinobu| Yamamoto, Kazuhide| |
| Abstract | We conducted a retrospective cohort study to investigate the predisposing factors for local recurrence and complications after percutaneous radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC). HCC patients (n＝397) consecutively treated with RFA (256 males, 141 females, median age 69 years) were enrolled. In these patients, 1,455 nodules (median size 17mm) were ablated. Predisposing factors for overall recurrence and local recurrence in the context of tumor location and complications were examined. Local recurrence was observed for 113 of the 1,455 nodules. The 1-, 3- and 5-year local recurrence rates were 2.2ｵ, 7.4ｵ and 9.5ｵ, respectively. A multivariate Cox proportional hazard analysis revealed that large tumor size (＞2cm), tumor location (adjacent to the major portal branch or hepatic vein), and small ablated margin (＜3mm) were independent predisposing factors for local recurrence after RFA (HR＝1.70-2.81). Tumor location (adjacent to the major portal branch, hepatic vein, or diaphragm) was also revealed as a risk factor for liver damage due to RFA. HCC adjacent to the major portal vein or hepatic vein was associated with a higher risk for local recurrence and for complications;therefore, special precautions are necessary when applying RFA to HCC near vessels even when the tumors are located at an easy-to-puncture site. |
| Keywords | hepatocellular carcinoma radiofrequency ablation ablated margin tumor location |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 219 |
| End Page | 226 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289913 |
| Web of Science KeyUT | 000365519100005 |
| JaLCDOI | 10.18926/AMO/53557 |
|---|---|
| FullText URL | 69_4_213.pdf |
| Author | Yumoto, Tetsuya| Sato, Keiji| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito| |
| Abstract | Hyponatremia, a common electrolyte disorder associated with traumatic brain injuries (TBIs), has high mortality and morbidity rates. The aim of this study was to identify the risk factors for hyponatremia associated with TBI. We retrospectively analyzed the cases of TBI patients who were admitted to the emergency intensive care unit at Okayama University Hospital between October 2011 and September 2014. A total of 82 TBI patients were enrolled. The incidences of hyponatremia (serum sodium level of＜135mEq/L) and severe hyponatremia (serum sodium level of＜130mEq/L) within the first 14 days after admission were 51ｵ (n＝42) and 20ｵ (n＝16), respectively. After admission, hyponatremia took a median period of 7 days to develop and lasted for a median of 3 days. Multivariate analysis demonstrated that higher fluid intake from days 1 to 3 and the presence of cranial fractures were risk factors for hyponatremia. The 58 patients with hyponatremia experienced fewer ventilator-free days, longer intensive care unit stays, and less favorable outcomes compared to the 24 patients without hyponatremia;however, these differences were not significant. Further studies are needed to determine the optimal management strategy for TBI-associated hyponatremia in the intensive care unit setting. |
| Keywords | traumatic brain injury hyponatremia cranial fracture fluid intake |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 213 |
| End Page | 218 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289912 |
| Web of Science KeyUT | 000365519100004 |
| JaLCDOI | 10.18926/AMO/53556 |
|---|---|
| FullText URL | 69_4_205.pdf |
| Author | Okada, Yoshiki| Endo, Hirosuke| Mitani, Shigeru| Fujiwara, Kazuo| Tetsunaga, Tomonori| Kagawa, Yohei| Fujii, Yosuke| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Abstract | Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15ｵ, 9.0ｵ, 6.0ｵ, and 6.4ｵ, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0ｵ), minor bleeding in 2 cases (2.0ｵ), persistent wound drainage in 3 cases (3.0ｵ), and eruption in 1 case (1.0ｵ). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0ｵ) and progression of anemia in 1 case (1.0ｵ). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases. |
| Keywords | total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 205 |
| End Page | 212 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289911 |
| Web of Science KeyUT | 000365519100003 |
| Related Url | http://doi.org/10.18926/AMO/53680 |
| JaLCDOI | 10.18926/AMO/53555 |
|---|---|
| FullText URL | 69_4_197.pdf |
| Author | Ishibashi, Naoki| Miyasho, Koji| Kitamura, Tetsuhisa| Ookuma, Takaaki| Kashitani, Nobuhiro| Beika, Nobuhiko| Yamashita, Takahiro| Ujike, Yoshihito| |
| Abstract | We evaluated the hemodynamics and outcomes of septic shock (SS) patients who did not respond to fluid resuscitation, after treatment with or without intravenous calcium. We retrospectively collected information on 154 eligible SS patients who were admitted to Fukuyama City Hospital Emergency Medical Center and did not respond to fluid resuscitation. To compare their degree of hemodynamic impairment, we compared the changes in the vasoactive-inotropic score (VIS) in the calcium-treated group (n＝112) and the noncalcium-treated group (n＝42). We compared the length of stay in the intensive care unit (ICU) and hospital, in-hospital deaths, 28-day deaths, and changes in the Sequential Organ Failure Assessment score within 72h of ICU admission between the 2 groups. Changes in the VIS at 1h after the baseline time were significantly greater in the calcium-treated group than in the noncalcium-treated group (1.41 vs. －1.25, respectively;p＜0.001). However, the changes in the VIS at 3, 6, 24, 48, and 72h did not differ between the 2 groups. The secondary outcomes also did not differ between the groups. Our findings indicate that calcium administered to SS patients might reduce their hemodynamic stabilization, but only for a short time after its administration. |
| Keywords | hemodynamics calcium shock sepsis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 197 |
| End Page | 204 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289910 |
| Web of Science KeyUT | 000365519100002 |
| JaLCDOI | 10.18926/AMO/53554 |
|---|---|
| FullText URL | 69_4_189.pdf |
| Author | Yamashita, Mako| Katayama, Norihisa| Waki, Takahiro| Katsui, Kuniaki| Himei, Kengo| Takemoto, Mitsuhiro| Kanazawa, Susumu| |
| Abstract | This study compared field-in-field (FIF) radiotherapy with conformal radiotherapy with physical wedges for the treatment of unilateral cervical malignant lymphoma. Two treatment plans, the FIF technique and conformal RT, were generated for each of 32 patients with unilateral cervical malignant lymphoma. To compare the 2 treatment plans, dose-volume histograms of the planning target volume (PTV), the thyroid, submandibular gland, carotid artery, mucosa, spinal cord, and surrounding normal tissue, and monitor unit (MU) were analyzed. The FIF technique showed significant reduction in the mean dose of thyroid, submandibular gland, carotid artery and mucosa, the maximum dose of the spinal cord and PTV, and the volume receiving＞107% of the prescribed dose of surrounding normal tissue (p＜0.001). In addition, there were gains in the homogeneity index of the PTV for FIF. Furthermore, the total MU was also lower for the FIF technique than for the wedge technique (p＜0.001). Compared with the wedge technique, the FIF technique improved the dose homogeneity of the PTV, reduced the dose to normal structures, and was associated with fewer MUs in the treatment of patients with cervical malignant lymphoma. |
| Keywords | field-in-field technique wedge lymphoma monitor units dose-volume histogram |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289909 |
| Web of Science KeyUT | 000365519100001 |
| JaLCDOI | 10.18926/AMO/53526 |
|---|---|
| FullText URL | 69_3_183.pdf |
| Author | Haruma, Tomoko| Ogawa, Chikako| Nishida, Takeshi| Kusumoto, Tomoyuki| Nakamura, Keiichiro| Seki, Noriko| Katayama, Takaaki| Hiramatsu, Yuji| |
| Abstract | Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up. |
| Keywords | choriocarcinoma ovary Silver-Russell syndrome |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 183 |
| End Page | 188 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101195 |
| Web of Science KeyUT | 000356903000008 |
| JaLCDOI | 10.18926/AMO/53525 |
|---|---|
| FullText URL | 69_3_177.pdf |
| Author | Hoshijima, Mitsuhiro| Honjo, Tadashi| Moritani, Norifumi| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi| |
| Abstract | This article reports the case of a 44-year-old male with skeletal Class III, Angle Class III malocclusion and unilateral crossbite with concerns about obstructive sleep apnea syndrome (OSAS), esthetics and functional problems. To correct the skeletal deformities, the maxilla was anteriorly repositioned by employing LeFort I osteotomy following pre-surgical orthodontic treatment, because a mandibular setback might induce disordered breathing and cause OSAS. After active treatment for 13 months, satisfactory occlusion was achieved and an acceptable facial and oral profile was obtained. In addition, the apnea hypopnea index (AHI) decreased from 18.8 preoperatively to 10.6 postoperatively. Furthermore, after a follow-up period of 7 months, the AHI again significantly decreased from 10.6 to 6.2. In conclusion, surgical advancement of the maxilla using LeFort I osteotomy has proven to be useful in patients with this kind of skeletal malocclusion, while preventing a worsening of the OSAS. |
| Keywords | LeFort I osteotomy maxillary advancement unilateral crossbite obstructive sleep apnea syndrome |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 182 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101194 |
| Web of Science KeyUT | 000356903000007 |
| JaLCDOI | 10.18926/AMO/53524 |
|---|---|
| FullText URL | 69_3_173.pdf |
| Author | Shirakawa, Yasuhiro| Noma, Kazuhiro| Ohara, Toshiaki| Kashima, Hajime| Maeda, Naoaki| Tanabe, Shunsuke| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment options are conservative management, interventional radiologic embolization, and surgery. Thoracoscopic ligation of the thoracic duct has emerged as a promising and definitive treatment. The case of a 65-year-old Japanese male patient with a rare congenital right aortic arch (typeⅢB1 of Edwardʼs classification) and a severe chyle leak that occurred after a total pharyngolaryngo-esophagectomy (TPLE) is described. The chyle leak was successfully managed by thoracoscopic ligation of the thoracic duct via a left-side approach with the patient in the prone position. |
| Keywords | chyle leak thoracic duct thoracoscopy prone position |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 173 |
| End Page | 176 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101193 |
| Web of Science KeyUT | 000356903000006 |
| JaLCDOI | 10.18926/AMO/53523 |
|---|---|
| FullText URL | 69_3_165.pdf |
| Author | Sarai, Takaaki| Tokumoto, Akihiro| |
| Abstract | Fall accidents are a common cause of femoral fracture in the elderly. The greater trochanter of the femur is often subjected to impact loading by a sideways fall, and thus it is worth studying the impulsive stress waves propagating in the femur. In this study, the impulsive stress was analyzed by the dynamic finite element method using a 3-dimensional model of the femur, and the influence of the fall configuration on the stress was discussed. The stress was concentrated around the femoral neck during the propagation of the stress wave, and the tensile maximum principal stress changed into compressive minimum principle stress on the anterior and medial sides of the neck. On the other hand, the compressive minimum principal stress changed into tensile maximum principle stress on the lateral side of the neck. The largest maximum principal stress during the impact loading was always larger in the neck than in the impact region. The largest absolute value of the minimum principal stress was found in the neck or the impact region depending on the fall configuration. The largest absolute values of the maximum and minimum principal stress were nearly equal, indicating that the bone fracture due to the tensile stress may occur around the femoral neck. |
| Keywords | biomechanics sideways fall femoral neck greater trochanter impulsive stress wave |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 165 |
| End Page | 171 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101192 |
| Web of Science KeyUT | 000356903000005 |
| JaLCDOI | 10.18926/AMO/53522 |
|---|---|
| FullText URL | 69_3_155.pdf |
| Author | Mikamo, Shoko| Nakatsuka, Mikiya| |
| Abstract | To assess the knowledge and attitudes of pregnant Japanese women regarding non-invasive prenatal testing (NIPT). Between March and June 2013, 557 pregnant women in the Hyogo and Hiroshima Prefectures were surveyed using an anonymous, self-completed questionnaire. A total of 91.9ｵ respondents (512/557) stated that they “agree” or “conditionally agree” with NIPT implementation in Japan. Approximately 28.5ｵ of respondents stated that they knew that the accuracy of a positive NIPT result can be affected by motherʼs age and background, while 34.5ｵ of respondents stated that it was necessary for pregnant women with a positive result to undergo fetal chromosome diagnosis using amniocentesis;both percentages were low. Additionally, 92.3ｵ of respondents would “like a detailed explanation of the test,” 65.1ｵ of them would “like psychological support if the NIPT test results came back positive,” and 5.7ｵ would terminate the pregnancy if the NIPT test results came back positive without undergoing fetal chromosome diagnosis via amniocentesis. Although a high proportion of pregnant Japanese women agreed with the introduction of NIPT into Japanese obstetrical care, there was insufficient knowledge regarding the test. It is necessary for women undergoing NIPT to be provided sufficient information and psychological support. |
| Keywords | amniocentesis Down syndrome fetal chromosome diagnosis non-invasive prenatal testing psychological support |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 155 |
| End Page | 163 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101191 |
| Web of Science KeyUT | 000356903000003 |
