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JaLCDOI 10.18926/AMO/69851
FullText URL 79_6_469.pdf
Author Tsujii, Teruyuki| Matsuda, Tatsuo| Kimura, Yuji| Katsube, Ryoichi| Iwadou, Hironori| Funabiki, Sadami| Kamikawa, Yasuaki| Matsuda, Tadakazu|
Abstract We report a rare case of ileus tube-related intussusception in an adult. A 56-year-old man with adhesive bowel obstruction was treated with a nasointestinal ileus tube. Although his condition initially improved, persistent abdominal pain led to the diagnosis of intussusception via CT imaging. Manual repositioning of the tube resolved the intussusception without the need for bowel resection. A review of 80 previously reported cases of ileus tube-associated intussusception (total 81 cases, 95 lesions) highlighted the timing of onset, treatment strategies, and precautions. Early detection and diagnosis are crucial to prevent severe complications and preserve bowel function.
Keywords nasointestinal ileus tube intussusception small bowel obstruction enterectomy conservative treatment
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 469
End Page 474
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69850
FullText URL 79_6_463.pdf
Author Asano, Yudai| Nishihara, Chika| Kitayama, Takahiro| Okawa, Nanako| Makimoto, Satoko| Higaki, Fumiyo| Kojima, Katsuhide| Sugihara, Hanako| Ida, Naoyuki| Yanai, Hiroyuki| Hiraki, Takao|
Abstract We present a case of a woman in her 70s who was diagnosed with mesonephric adenocarcinoma of the uterine cervix, following biopsy and surgery. Preoperative MRI revealed a 7-cm, well-defined circumferential cervical mass with left lateral wall predominance, bulging into the uterine cavity and vagina. The lesion showed intermediate signal intensity on T2-weighted images, diffusion restriction, and early contrast enhancement weaker than that of the myometrium, followed by washout on contrast-enhanced imaging. The circumferential growth pattern with the lateral wall predominance and its imaging characteristics may suggest this rare entity be routinely included in the differential diagnosis of cervical cancers.
Keywords mesonephric adenocarcinoma cervical cancer MRI imaging characteristics HPV-independent adenocarcinoma
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 463
End Page 468
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69849
FullText URL 79_6_457.pdf
Author Asakawa, Tomohiko| Uchida, Haruhito A.| Katayama, Yu| Sakurabu, Yoshimasa| Katayama, Katsuyoshi| Onishi, Yasuhiro| Matsuoka-Uchiyama, Natsumi| Takeuchi, Hidemi| Tanaka, Keiko| Tsuji, Kenji| Umebayashi, Ryoko| Takemoto, Rika| Wada, Jun|
Abstract This case involves a 23-year-old male who was diagnosed with Behçet’s disease 5 years ago and managed with colchicine. Two months ago, he underwent renal biopsy due to abnormal urinalysis and kidney dysfunction, leading to a diagnosis of IgA nephropathy. He subsequently underwent tonsillectomy followed by glucocorticoid pulse therapy. However, after the tonsillectomy, discontinuing colchicine led to increased proteinuria, despite the glucocorticoid pulse therapy. Upon reintroducing colchicine, urinary protein excretion decreased, achieving incomplete remission. These findings suggest that colchicine may be effective in decreasing proteinuria in patients with Behçet’s disease complicated by IgA nephropathy.
Keywords Behçet’s disease IgA nephropathy colchicine
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 457
End Page 461
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69848
FullText URL 79_6_451.pdf
Author Hagihara, Moe| Seike, Keisuke| Hayashino, Kenta| Yasuhara, Takao| Kin, Kyohei| Hirata, Yuichi| Kobayashi, Hiroki| Kitamura, Wataru| Fujiwara, Hideaki| Asada, Noboru| Fujii, Nobuharu| Maeda, Yoshinobu|
Abstract Emicizumab, a bispecific monoclonal antibody, benefits patients with severe hemophilia A. It alters laboratory assessments of coagulation activity, requiring anti-idiotype monoclonal antibodies for accurate monitoring. A 64-year-old man, receiving emicizumab regularly, was admitted for laminoplasty. We planned to use FVIII replacement during the perioperative period after confirming the disappearance of inhibitors, monitoring coagulation activity with anti-idiotype monoclonal antibodies. Activated partial thromboplastin time was prolonged on postoperative day 2, prompting an immediate switch to eptacog alfa. The patient recovered without bleeding. This case underscores the necessity of anti-idiotype monoclonal antibodies for accurate monitoring.
Keywords emicizumab eptacog alfa hemophilia A inhibitor anti-idiotype monoclonal antibodies to emicizumab
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 451
End Page 455
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69847
FullText URL 79_6_445.pdf
Author Matsumi, Junya|
Abstract Our hospital began a PERIO program (perioperative patient management by a multi-disciplinary team from multiple departments) in 2016 to improve patient outcomes. We retrospectively analyzed the clinical effects of the PERIO program regarding the postoperative hospital stay (PHS) in the patients aged ≥ 18 years who underwent long lower-abdominal surgery at our hospital during the period April 2019 to March 2023. We excluded the cases of patients whose general anesthesia use was < 8 h, those for whom another surgery was performed simultaneously at another site, and emergency surgeries. The outcome was prolonged PHS, defined as exceeding the scheduled number of days specified in the patient’s clinical pathway. Among the 480 patients, prolonged PHS was observed for 270 patients (56.3%). In a multivariate logistic regression using advanced age, sex, high-risk general state, surgery requiring colon resection, serious adverse events (SAEs), and PERIO use, the following were associated with prolonged PHS: advance age (odds ratio [OR] 4.91, 95% confidence interval [CI]: 2.68-8.99, p=0.01), surgery requiring colon resection (OR 4.91, 95%CI: 2.68-8.99, p<0.001), SAE (OR 18.7, 95%CI: 7.22-48.2, p<0.001), and PERIO (OR 0.25, 95%CI: 0.13-0.47, p<0.001). The use of the PERIO program was thus beneficially associated with PHS after long lower-abdominal surgery.
Keywords hospital stay ERAS surgery cancer perioperative management
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 445
End Page 449
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69846
FullText URL 79_6_437.pdf
Author Matsumi, Junya| Sato, Tetsufumi|
Abstract The optimal indications for intensive care unit (ICU) treatment for critically ill cancer survivors whose condition has deteriorated due to medical factors are unclear. To test our hypothesis that frailty before deterioration was associated with hospital mortality in this patient population, we retrospective analyzed the cases of the patients admitted to the ICU at the National Cancer Center Hospital, Japan (April 2014-March 2022). We excluded patients who underwent surgery within 28 days or were denied critical care within 24 h or admitted after cardiopulmonary arrest. Their Clinical Frailty Scale (CFS) scores at 1 month before ICU admission (Pre-ICU) were obtained. Frailty was defined as CFS scores ≥4 points. We analyzed 298 admissions and observed that the mortality rate at hospital discharge was significantly higher in the frailty group (n=119). A multivariate analysis demonstrated that the following factors were significantly associated with hospital mortality: Pre-ICU frailty (OR 2.00, 95%CI: 1.19-3.36, p=0.009), cancer type (hematological: OR 2.93, 95%CI: 1.42-6.05, p=0.004), and Sequential Organ Failure Assessment score at ICU admission (OR 0.88, 95%CI: 0.82-0.95, p=0.0008). Frailty retrospectively assessed using the CFS at 1 month pre-ICU admission is a risk factor for hospital mortality in these cancer survivors.
Keywords frailty cancer survivor clinical frailty scale cancer critically ill
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 437
End Page 444
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69843
FullText URL 79_6_413.pdf
Author Jiang, Zhiyun| Xi, Ying|
Abstract Several observational studies suggested that migraine headache attacks were associated with coronavirus disease 2019 (COVID-19). We investigated genetic causal links between COVID-19 phenotypes and the development of headache and migraine, including migraine with aura (MA) and migraine without aura (MO). We conducted a two-sample Mendelian randomization (MR) analysis to estimate the genetic association in European populations. The inverse-variance weighted (IVW) method was used as the main approach in the MR analyses, together with weighted median and MR-Egger methods. We also performed a series of sensitivity tests to assess the robustness of the MR results. The MR results demonstrated that COVID-19 severity, hospitalization, and susceptibility had no causal effect on the risks of headache, migraine, MA, or MO. No horizontal pleiotropy was detected, and the results were robust as supported by the sensitivity analysis findings. Our analyses identified no casual effect of COVID-19 severity, hospitalization, or susceptibility on the risks of headache or migraine in European populations.
Keywords headache migraine Mendelian randomization COVID-19
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 413
End Page 419
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/69842
FullText URL 79_6_405.pdf
Author Ouchi, Chihiro| Morizane Hosokawa, Mio| Kimura, Shuhei| Shiode, Yusuke| Matoba, Ryo| Morita, Tetsuro| Morizane, Yuki|
Abstract We investigated the treatment outcomes of patients aged ≥85 years with neovascular age-related macular degeneration (nAMD) who received anti-vascular endothelial growth factor (anti-VEGF) therapy using either treat-and-extend (TAE) or pro re nata (PRN) regimens for 1 year in real-world clinical practice. Eighty-five eyes from 85 patients were included. Among them, types 1, 2, and 3 macular neovascularization and polypoidal choroidal vasculopathy were present in 27.1%, 17.6%, 18.8%, and 36.5%, respectively. TAE and PRN regimens were used in 43.5% and 56.5% of patients, respectively. At baseline, the PRN group was older and had worse best-corrected visual acuity (BCVA), greater central retinal thickness, and more intraretinal fluid than the TAE group. In the TAE group, the mean number of injections was 7.6, BCVA improved significantly, and all retinal fluid rates decreased. In the PRN group, the mean number of injections was 3.9, BCVA remained unchanged, and the rates of macular fibrosis and atrophy increased. No serious adverse events were observed in either group. Anti-VEGF therapy was safe for patients aged ≥ 85 years with nAMD, and the TAE regimen effectively improved BCVA in this population. BCVA remained unchanged in the PRN-treated patients, with baseline disease severity and/or undertreatment potentially influencing the outcomes.
Keywords anti-vascular endothelial growth factor therapy neovascular age-related macular degeneration age treat-and-extend pro re nata
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 405
End Page 412
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Miyoshi, Kanako| Mori, Keiko|
Keywords adult day service clinical judgement community home care multidisciplinary collaboration nurses persons requiring care
Published Date 2025-12-14
Publication Title International Journal of Older People Nursing
Volume volume21
Issue issue1
Publisher Wiley
Start Page e70052
ISSN 1748-3735
NCID AA12157107
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 41392442
DOI 10.1111/opn.70052
Related Url isVersionOf https://doi.org/10.1111/opn.70052
FullText URL fulltext.pdf
Author Shiraishi, Wataru| Nishimura, Shion| Maeda, Morihiro| Ueno, Hideto|
Keywords drip fertigation eggplant greenhouse cultivation nitrogen leaching nitrogen use efficiency nitrous oxide emissions
Published Date 2025-12-16
Publication Title Nitrogen
Volume volume6
Issue issue4
Publisher MDPI AG
Start Page 116
ISSN 2504-3129
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
DOI 10.3390/nitrogen6040116
Related Url isVersionOf https://doi.org/10.3390/nitrogen6040116
FullText URL fulltext.pdf
Author Ogura, Takeshi| Tanisaka, Yuki| Sekine, Masanari| Kobayashi, Katsumasa| Maruyama, Hirotsugu| Hirai, Shinji| Shiomi, Hideyuki| Shigekawa, Minoru| Kuwatani, Masaki| Ikezawa, Kenji| Itonaga, Masahiro| Takenaka, Mamoru| Hijioka, Susumu| Ikeura, Tsukasa| Doi, Shinpei| Fujimori, Nao| Koizumi, Kazuya| Nakai, Yousuke| Inoue, Tadahisa| Mukai, Shuntaro| Matsumoto, Kazuyuki| Minami, Ryuki| Mandai, Koichiro| Matsuda, Atsuhiro| Iwashita, Takuji| Kawashima, Hiroki| Itoi, Takao|
Keywords ERCP guidewire pancreatitis post-ERCP pancreatitis wire-guided cannulation
Published Date 2025-06-16
Publication Title DEN Open
Volume volume6
Issue issue1
Publisher Wiley
Start Page e70144
ISSN 2692-4609
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40529106
DOI 10.1002/deo2.70144
Web of Science KeyUT 001509910300001
Related Url isVersionOf https://doi.org/10.1002/deo2.70144
FullText URL fulltext.pdf
Author Kobayashi, Satoshi| Nakachi, Kohei| Yamamoto, Kouji| Ueno, Makoto| Maruki, Yuta| Ikezawa, Kenji| Terashima, Takeshi| Shimizu, Satoshi| Oshima, Kotoe| Tsuji, Kunihiro| Masaki, Yoshiharu| Tsumura, Hidetaka| Shibuki, Taro| Ozaka, Masato| Okano, Naohiro| Okamura, Yukiyasu| Umemoto, Kumiko| Satoh, Tatsunori| Kojima, Yasushi| Shioji, Kazuhiko| Nebiki, Hiroko| Doi, Toshifumi| Naganuma, Atsushi| Kataoka, Shigeki| Kita, Emiri| Asama, Hiroyuki| Tsuchiya, Kaoru| Unno, Michiaki| Ashida, Reiko| Matsumoto, Kazuyuki| Ohno, Izumi| Itoi, Takao| Negoro, Yuji| Sakamoto, Yasunari| Arima, Shiho| Asagi, Akinori| Okuyama, Hiroyuki| Komatsu, Yoshito| Kobayashi, Noritoshi| Nagano, Hiroaki| Furuse, Junji|
Keywords Biliary tract cancer Unresectable Chemotherapy Older Survival
Published Date 2025-09-06
Publication Title Journal of Gastroenterology
Volume volume60
Issue issue12
Publisher Springer Science and Business Media LLC
Start Page 1584
End Page 1595
ISSN 0944-1174
NCID AA10988015
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40913639
DOI 10.1007/s00535-025-02294-0
Web of Science KeyUT 001567162600001
Related Url isVersionOf https://doi.org/10.1007/s00535-025-02294-0
FullText URL fulltext.pdf
Author Tsuge, Takahiro| Yamamoto, Norio| Tomita, Yosuke| Hagiyama, Akikazu| Shiratsuchi, Daijo| Okamura, Masatsugu| Kaneko, Takao| Suzuki, Kosuke| Nakashima, Yuki| Taito, Shunsuke| Yorifuji, Takashi|
Keywords citation grade journal impact factor methodological and reporting quality prisma
Published Date 2025-10-29
Publication Title Cureus
Volume volume17
Issue issue10
Publisher Springer Science and Business Media LLC
Start Page e95695
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Tsuge et al.
File Version publisher
PubMed ID 41322874
DOI 10.7759/cureus.95695
Related Url isVersionOf https://doi.org/10.7759/cureus.95695
FullText URL fulltext.pdf
Author Shitozawa, Hisakazu| Misawa, Haruo| Oda, Yoshiaki| Joko, Ryoji| Takahashi, Masaya| Uotani, Koji| Shiozaki, Yasuyuki| Tetsunaga, Tomoko| Shinohara, Kensuke| Nakamichi, Ryo| Ueda, Masataka| Takatori, Ryo| Yamashita, Kazutaka| Ozaki, Toshifumi|
Keywords balloon kyphoplasty cement-catching screw intermediate screws osteoporotic vertebral fractures pullout strength
Published Date 2025-06-13
Publication Title Cureus
Volume volume17
Issue issue6
Publisher Springer Science and Business Media LLC
Start Page e85955
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Shitozawa et al.
File Version publisher
PubMed ID 40656326
DOI 10.7759/cureus.85955
Related Url isVersionOf https://doi.org/10.7759/cureus.85955
FullText URL fulltext.pdf
Author Okuda, Ryuichiro| Tetsunaga, Tomonori| Yamada, Kazuki| Tetsunaga, Tomoko| Koura, Takashi| Inoue, Tomohiro| Masada, Yasutaka| Yamamoto, Tetsuya| Matsumoto, Shin| Ikuma, Hisanori| Komatsubara, Tadashi| Okazaki, Yuki| Ozaki, Toshifumi|
Keywords Total hip arthroplasty Femoral artery Femoral nerve Computed tomography Lateral position Supine position
Published Date 2025-07-15
Publication Title Archives of Orthopaedic and Trauma Surgery
Volume volume145
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 373
ISSN 1434-3916
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40664911
DOI 10.1007/s00402-025-05968-9
Web of Science KeyUT 001529672000003
Related Url isVersionOf https://doi.org/10.1007/s00402-025-05968-9
FullText URL K0007418_abstract_review.pdf K0007418_fulltext.pdf K0007418_summary.pdf
Author DAITO, Maki|
Published Date 2025-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7418号
Granted Date 2025-09-25
Thesis Type Doctor of Philosophy in Health Sciences
Grantor 岡山大学
language Japanese
Copyright Holders © 2023 一般社団法人日本作業療法士協会
FullText URL K0007364_abstract_review.pdf K0007364_fulltext.pdf K0007364_other.pdf K0007364_summary.pdf
Author FUJIWARA, Shintaro|
Published Date 2025-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7364号
Granted Date 2025-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2023 World Obesity Federation.
FullText URL K0007363_abstract_review.pdf K0007363_fulltext.pdf K0007363_summary.pdf
Author SASAI (FUJITA), Kana|
Published Date 2025-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7363号
Granted Date 2025-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2023 by the authors.
FullText URL K0007351_abstract_review.pdf K0007351_fulltext.pdf K0007351_summary.pdf
Author GOHARA, Yuma|
Published Date 2025-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7351号
Granted Date 2025-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © The Author(s) 2023
FullText URL fulltext.pdf
Author Kubota, Yuta| Kawano, Masanori| Iwasaki, Tatsuya| Itonaga, Ichiro| Kaku, Nobuhiro| Ozaki, Toshifumi| Tanaka, Kazuhiro|
Keywords NTRK fusion-positive sarcoma larotrectinib entrectinib infantile fibrosarcoma NTRK-rearranged spindle cell neoplasms
Published Date 2025-02-03
Publication Title Japanese Journal of Clinical Oncology
Volume volume55
Issue issue4
Publisher Oxford University Press (OUP)
Start Page 313
End Page 326
ISSN 1465-3621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 39895082
DOI 10.1093/jjco/hyaf015
Web of Science KeyUT 001410814800001
Related Url isVersionOf https://doi.org/10.1093/jjco/hyaf015