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JaLCDOI 10.18926/AMO/62396
FullText URL 75_4_447.pdf
Author Kono, Reika| Hamasaki, Ichiro| Kishimoto, Fumiko| Ohtuski, Hiroshi| Shibata, Kiyo| Morizane, Yuki| Shiraga, Fumio|
Abstract In high myopia, eye dislocation due to increased globe volume or tight orbital volume causes acquired esotro-pia. GOR (globe/orbit volume ratio), an indicator of the degree of progression of this pathology, was investi-gated the relationships among easily obtained clinical parameters. In this retrospective study, 20 eyes from 10 acquired esotropia patients with high myopia but without abduction limitations were examined. The mean age of the patients was 63.7 ± 8.2 years (mean ± standard deviation). Volumes were measured on the three-dimen-sional fast imaging employing steady-state acquisition magnetic resonance imaging images using the vol-ume-measurement function. Correlations between GOR and the displacement angle of the globe (DA), axial length (AL), and equatorial diameter (ED) were investigated. Mean DA, AL, ED, and GOR values were 107.5 ± 8.5°, 28.86 ± 1.92 mm, 25.00 ± 1.16 mm, and 0.36 ± 0.05, respectively. Only AL was correlated with GOR (p < 0.0001, R2 = 0.6649); DA (p = 0.30, R2 = 0.0633) and ED (p = 0.91, R2 = 0.0008) were not. AL was the only clinically available parameter to indicate globe/orbit volume imbalances in acquired esotropia with high myopia but without abduction limitation. AL may be important for the clinical assessment of the progression of this pathology.
Keywords acquired esotropia high myopia (high myopes) globe volume magnetic resonance imaging limitation of abduction
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 447
End Page 453
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511611
Web of Science KeyUT 000697944600006
NAID 120007146039
JaLCDOI 10.18926/okadaironkou/60141
FullText URL okadaironkou_31_53_62.pdf
Author 白神 由紀江|
Publication Title 岡大国文論稿
Published Date 2003-03-31
Issue issue31
Start Page 53
End Page 62
ISSN 0386-3123
language Japanese
File Version publisher
NAID 40005896061
FullText URL fulltext.pdf
Author Kanzaki, Yuki| Fujita, Hirofumi| Sato, Keita| Hosokawa, Mio| Matsumae, Hiroshi| Shiraga, Fumio| Morizane, Yuki| Ohuchi, Hideyo|
Keywords Kir7.1 KCNJ13 human-induced pluripotent cells retinal pigment epithelium phagocytosis
Published Date 2020-05
Publication Title Investigative Ophthalmology & Visual Science
Volume volume61
Issue issue5
Publisher Association for Research in Vision and Ophthalmology
Start Page 38
ISSN 0146-0404
NCID AA00683736
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright 2020 The Authors
File Version publisher
PubMed ID 32437550
DOI 10.1167/iovs.61.5.38
Web of Science KeyUT 000540905500039
Related Url isVersionOf https://doi.org/10.1167/iovs.61.5.38
FullText URL fulltext.pdf
Author Morisawa, Shin| Hamasaki, Ichiro| Shibata, Kiyo| Shimizu, Takehiro| Kono, Reika| Miyata, Manabu| Furuse, Takashi| Hasebe, Satoshi| Ohtsuki, Hiroshi| Morizane, Yuki| Shiraga, Fumio|
Keywords Intermittent exotropia Postoperative exo-drift Recurrent exotropia Recession and resection procedure Strabismus surgery
Published Date 2020-06-05
Publication Title BMC Ophthalmology
Volume volume20
Issue issue1
Publisher BMC
ISSN 1471-2415
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 32503457
DOI 10.1186/s12886-020-01484-z
Web of Science KeyUT 000540232800002
Related Url isVersionOf https://doi.org/10.1186/s12886-020-01484-z
JaLCDOI 10.18926/AMO/59956
FullText URL 74_3_229.pdf
Author Shibata, Kiyo| Hamasaki, Ichiro| Toshima, Shinji| Shimizu, Takehiro| Kono, Reika| Miyata, Manabu| Morisawa, Shin| Furuse, Takashi| Hasebe, Satoshi| Ohtsuki, Hiroshi| Morizane, Yuki| Shiraga, Fumio|
Abstract The purpose of this study was to derive new formulas to provide an optimal surgical procedure and optimal amount of recession-resection (RR) surgery in intermittent exotropia (IXT) with a disparity in angle of deviation depending on the fixation distance. The records of 117 consecutive patients with IXT who underwent RR surgery between March 2008 and December 2011 at Okayama University Hospital were retrospectively examined. Multivariable linear regression analysis was performed using the observed corrective angle of deviation at distance or near fixation as the dependent variable, and amounts of lateral rectus muscle (LR) recession (mm) and medial rectus muscle (MR) resection, and age at surgery (years) as independent variables. Two simultaneous formulas were derived: corrective angle of deviation at distance fixation (°)=1.8×recession (mm)+1.6× resection (mm)+0.15×age (years)–6.6, and corrective angle at near fixation (°)=1.5×recession (mm)+1.7× resection (mm)+0.18×age (years)–3.8. Comparisons of coefficient values of the formulas between distance and near fixation revealed that LR recession was more affected by the corrective angle in distance than near fixation. MR resection was more affected at near than distance fixation. We found that our new formulas estimated the appropriate amount of unilateral RR surgery.
Keywords surgical amount intermittent exotropia recession and resection procedure strabismus surgery recurrent exotropia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-06
Volume volume74
Issue issue3
Publisher Okayama University Medical School
Start Page 229
End Page 236
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32577021
FullText URL fulltext.pdf tables.pdf Fig1.tif Fig2.jpg Fig3.tif Fig4.tif Fig5.tif
Author Kono, Reika| Ohtsuki, Hiroshi| Kishimoto, Fumiko| Hamasaki, Ichiro| Morizane, Yuki| Shiraga, Fumio|
Keywords age-related distance esotropia esotropia high myopia orbital pulley sagging eye syndrome
Published Date 2019-01-22
Publication Title Graefe's Archive for Clinical and Experimental Ophthalmology
Volume volume257
Publisher Springer
Start Page 662
End Page 662
ISSN 0721832X
NCID AA11623893
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 30671656
DOI 10.1007/s00417-019-04250-0
Web of Science KeyUT 000459788800025
Related Url isVersionOf https://doi.org/10.1007/s00417-019-04250-0
JaLCDOI 10.18926/AMO/57716
FullText URL 73_6_517.pdf
Author Hosogi, Mika| Shiode, Yusuke| Morizane, Yuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Toshima, Shinji| Takahashi, Kosuke| Fujiwara, Atsushi| Shiraga, Fumio|
Abstract We investigated the effectiveness of a treat-and-extend regimen (TAE) of intravitreal ranibizumab injections for macular edema (ME) due to branch retinal vein occlusion (BRVO). We retrospectively examined 2-year results of 32 eyes of 32 patients who underwent TAE to treat ME due to BRVO. The patients whose treatment interval extended to ≥ 12 weeks were switched to a pro re nata regimen (PRN). For the patients whose treatment interval was <12 weeks, TAE was continued. At 2 years, 10 eyes had required no additional injections after the initial treatment period [recurrence(−) group], whereas the other 22 eyes required additional treatment [recurrence(+) group]. Among the recurrence(+) patients, 11 eyes (34.4% of total) were eventually switched from TAE to PRN; the other 11 eyes (34.4%) continued TAE for 2 years. Visual acuity and central retinal thickness were significantly improved in both the recurrence(+) and (−) groups, and there was no significant betweengroup difference in visual acuity at 2 years. Univariate analyses revealed significant differences in visual acuity (p=0.004), age (p=0.014), and vessel occlusion site (p=0.018) between these groups. Our results suggest that TAE may be effective for BRVO patients with lower visual acuity, older age, and occlusion of a major vein.
Keywords branch retinal vein occlusion macular edema anti-vascular endothelial growth factor ranibizumab treat-and-extend regimen
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-12
Volume volume73
Issue issue6
Publisher Okayama University Medical School
Start Page 517
End Page 522
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31871334
Web of Science KeyUT 000503431400007
JaLCDOI 10.18926/AMO/57378
FullText URL 73_5_463.pdf
Author Shibata, Kiyo| Hamasaki, Ichiro| Shimizu, Takehiro| Kono, Reika| Ohtsuki, Hiroshi| Morizane, Yuki| Shiraga, Fumio|
Abstract To permit noose movement without fraying the sutures following strabismus surgery, we designed a new sliding noose, the “twist knot” and investigated its advantages and disadvantages. We measured the tensile strength required to move the twist knot in a tightly tied state (134±19 gf) and in a loosened state (21±7 gf), and that required to move the conventional sliding noose in a tightly tied state (48±14 gf), and used the Kruskal-Wallis test to compare them. A significant difference was observed among the three tensile strengths (p<0.001). The twist knot technique allowed easy sliding without the multifilament braided suture becoming frayed and a knot to be firmly fixed without slipping. However, if the 2 strings of the pole sutures exit from the sclera at 2 widely separated positions, the sliding noose may become slack. Therefore, the distance between the pole sutures should be small. The simple twist knot technique was found to be an effective approach following adjustable surgery of strabismus.
Keywords adjustable suture the new sliding noose method tensile strength strabismus surgery esotropia
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 463
End Page 468
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649374
Web of Science KeyUT 000491886600013
JaLCDOI 10.18926/CTED/55809
Title Alternative Educational Effects of Various Team Childcare Styles in Preschool Education
FullText URL cted_008_083_096.pdf
Author Baba, Noriko| Iyama, Fusako| Koyano, Hiroko| Shiraga, Shigeko| Hiramatsu, Yumiko| Moriya, Misao| Katayama, Mika|
Abstract 本論は,幼稚園で実践されているティーム保育について,その多様な形態を分類することを目的に,1県内全域の幼稚園に対する質問紙調査を行い,実証的に明らかにしたものである。ティーム保育の形態の分類は,保育経験豊富な研究協力者によって,質問紙調査の結果を基にしたグループディスカッションで検討され,各形態に見る教育効果や特性,運営上の課題が精査された。その結果,園内の全教師が1つのティームとなり,全園児を全教師で保育するという意識を強く持っていることが明らかになった。そのことを前提に,ティーム保育の形態について,次に示す3つの分類が見出された:①「教師の配置に注目したティーム保育の形態」,②「保育内容や生活を重視したティーム保育の形態」,③「幼児理解や保育等に関する保育時間外のティーム保育の形態」。
Keywords 幼稚園教育 (Preschool Education) ティーム保育 (Team Childcare) 形態 (Styles) 質問紙調査 (Questionnaire Method)
Publication Title Bulletin of Center for Teacher Education and Development, Okayama University
Published Date 2018-03-20
Volume volume8
Start Page 83
End Page 96
ISSN 2186-1323
language Japanese
Copyright Holders Copyright © 2018 岡山大学教師教育開発センター
File Version publisher
JaLCDOI 10.18926/AMO/55209
FullText URL 71_3_255.pdf
Author Kumase, Fumiaki| Morizane, Yuki| Kimura, Shuhei| Toshima, Shinji| Shiraga, Fumio|
Abstract  Parafoveal retinal holes (PRHs) are one of the complications that can occur after internal limiting membrane (ILM) peeling during macular surgery. Here we describe a patient in whom an exceptionally large PRH (1,069-μm dia.) was successfully closed by repeated autologous ILM transplantation.
Keywords autologous internal limiting membrane transplantation parafoveal retinal hole, macular surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2017-06
Volume volume71
Issue issue3
Publisher Okayama University Medical School
Start Page 255
End Page 257
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28655946
Title Alternative Inhibitory effects of caffeine on allergic rhinitis symptoms in mice
FullText URL poalas_033_018_021.pdf
Author Tsujimoto, Madoka| Saiki, Akiko| Suzuki, Manami| Shiraga, Toshiyuki| Sugimoto, Yukio| Hayashi, Yasushi|
Abstract We examined the effects of caffeine treatment on ovalbumin- and histamine-induced rhinitis mouse models and on corticosterone and catecholamine levels in mouse plasma. Treatment with caffeine decreased sneezing and nasal rubbing in both models, but direct nasal administration had no effect. Plasma levels of corticosterone and catecholamine, which have known anti-allergy effects, were increased by caffeine treatment. The increases in corticosterone and catecholamine may be associated with the suppression of rhinitis symptoms.
Publication Title Proceedings of Okayama Association for Laboratory Animal Science
Published Date 2017-04
Volume volume33
Start Page 18
End Page 21
language Japanese
File Version publisher
JaLCDOI 10.18926/CTED/54930
Title Alternative An Attempt at Curriculum Improvement through an Evaluation by External Experienced Childcare Workers
FullText URL cted_007_051_060.pdf
Author Baba, Noriko| Shimizu, Mariko| Iyama, Fusako| Kataoka, Kayoko| Koyano, Hiroko| Shiragami, Shigeko| Hiramatsu, Yumiko| Hachiya, Sachiko| Nishiyama, Osamu|
Abstract  本論は,保育現場における園のカリキュラム・マネジメントを活性化させるために,園外の保育経験者にカリキュラムの外部評価を依頼し,その評価内容と一連の評価方法について検討するものである。具体的には,地方政令市にあるA 保育園のカリキュラムを取り上げ,保育所保育士経験者及び幼稚園教諭経験者によって構成させる7名の外部評価者から,カリキュラムの評価を得た。その結果,外部評価者の勤務経験の違いを反映した,幅広い観点から,カリキュラムの評価できる点や問題点を確認することができた。カリキュラム改善の観点としては,「表記・表現の統一と分かりやすい様式の採用」「園の独自性や子どもの実態に即した計画の作成」「保健計画の作成」「PDCA サイクルによる再編成」「職員間での確認」の項目を明示することができた。カリキュラム改善の一方策として,保育経験者による外部評価に一定の有効性を確認した。
Keywords カリキュラム改善 (curriculum improvement) 保育経験者 (the childcare workers with experience) 外部評価 (external evaluation) 評価の観点 (viewpoints of evaluation)
Publication Title Bulletin of Center for Teacher Education and Development, Okayama University
Published Date 2017-03-27
Volume volume7
Start Page 51
End Page 60
ISSN 2186-1323
language Japanese
Copyright Holders Copyright © 2017 岡山大学教師教育開発センター
File Version publisher
JaLCDOI 10.18926/AMO/53678
FullText URL 69_5_313.pdf
Author Narita, Akiko| Seguchi, Jiro| Shiraga, Fumio|
Abstract Paecilomyces lilacinus (P. lilacinus) is a rare cause of fungal scleritis. We herein report a case of P. lilacinus-induced scleritis following bleb-associated endophthalmitis after trabeculectomy that was successfully treated with surgical excision of the affected sclera in combination with antifungal medication. An 85-year-old female underwent trabeculectomy of the left eye. A dellen formed in the corneal periphery due to limbal elevation of the filtering bleb and progressed to an infectious corneal ulcer, leading to blebitis. Eight days after the onset of blebitis, the patient was diagnosed with endophthalmitis, which resolved after vitrectomy. The growth of P. lilacinus was identified on swabs of the conjunctiva and the corneal specimen. Scleritis developed after the resolution of the endophthalmitis, and an early excision of the affected sclera, in addition to antifungal medication, resolved it completely. However, the scleritis recurred in a different region of the left eye. After 7 months of antifungal medication, the left eye showed no residual infection. When treating P. lilacinus-induced scleritis, surgical excision of the affected sclera has been shown to be an effective treatment strategy. Nevertheless, it is possible that the infection may recur in another part of the eyeball after the complete resolution of the primary lesion.
Keywords Paecilomyces lilacinus scleritis trabeculectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2015-10
Volume volume69
Issue issue5
Publisher Okayama University Medical School
Start Page 313
End Page 318
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26490029
Web of Science KeyUT 000365519600008
JaLCDOI 10.18926/bgeou/53572
Title Alternative Design for Toy-Robot with 5-Bar-Link Mechanism
FullText URL bgeou_159_071_077.pdf
Author Ohashi, Kazumasa| Shiraga, Yasuhiro|
Abstract リンク機構は,多種類の動きを生成することから,多くの動くおもちゃの基本メカニズムとして,欠かせない存在である。多節リンクを適用すれば,それぞれのリンクで各種動きを生成できるが,一方で,動きが一定にならなかったり,動かなくなったりする場合は多い。そこで本研究では,1つのリンクを駆動用に固定した5節リンク機構に注目し,目的の動きを得るための5節リンク機構の解法アルゴリズムの展開と,それを用いた設計方法について提案する。そして,適用例を示し,提案した設計方法の有用性について考察する。
Keywords 5節リンク機構 機構設計 解法アルゴリズム おもちゃ設計
Publication Title 岡山大学大学院教育学研究科研究集録
Published Date 2015-07-28
Volume volume159
Start Page 71
End Page 77
ISSN 1883-2423
language Japanese
File Version publisher
NAID 120005649256
JaLCDOI 10.18926/AMO/53028
FullText URL 68_6_379.pdf
Author Doi, Shinichiro| Kimura, Shuhei| Morizane, Yuki| Hosogi, Mika| Hosokawa, Mio| Shiode, Yusuke| Kawata, Tetsuhiro| Kondo, Eisei| Shiraga, Fumio|
Abstract We report a case of POEMS syndrome in a 20-year-old patient diagnosed after visiting an eye clinic with a chief complaint of reduced visual acuity. A male university student aged 20 years was referred to our department complaining of blurred vision in both eyes that had persisted for 1 month. He also noted headache, nausea, and paresthesia in the lower extremities around the same time. The visual acuity of his right and left eye was 20/40 and 20/20, respectively. Optic disc edema and serous retinal detachment were present. Brain magnetic resonance imaging showed no intracranial abnormalities, while elevated cerebrospinal fluid pressure, reduced nerve conduction velocity in both lower extremities, hepatosplenomegaly, M proteinemia, high blood VEGF levels, osteoblastic and osteolytic changes in the spine, and atypical plasma cells in bone lesions were noted. From the above findings, the patient was diagnosed with POEMS syndrome. He received high-dose dexamethasone, thalidomide, and radiotherapy on the sacral mass, followed by high-dose melphalan with autologous stem-cell support, and showed subsequent systemic and ophthalmologic improvement. Here, we report the youngest case ever of POEMS syndrome with ocular manifestation. If patients have optic disc edema in both eyes with no intracranial space-occupying lesion, POEMS syndrome should be considered in differential diagnosis, regardless of age.
Keywords POEMS syndrome serous retinal detachment VEGF
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2014-12
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 379
End Page 383
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519033
Web of Science KeyUT 000346882200009
Author 川上 公一| 白神 宏明|
Published Date 2003-10-10
Publication Title 岡山大学算数・数学教育学会誌 : パピルス
Volume volume10
Content Type Departmental Bulletin Paper
Author Tsumuki, H.| Kanehisa, K.| Shiraga, T.|
Published Date 1981-03-16
Publication Title 農学研究
Volume volume59
Issue issue2
Content Type Departmental Bulletin Paper
Author Kanehisa, K.| Yamashita, T.| Shiraga, T.|
Published Date 1981-03-16
Publication Title 農学研究
Volume volume59
Issue issue2
Content Type Departmental Bulletin Paper
Author Kanehisa, Katsuo| Tsumuki, Hisaaki| Shiraga, Takashi| Kawada, Kazuo|
Published Date 1987-03
Publication Title 農学研究
Volume volume61
Issue issue3
Content Type Departmental Bulletin Paper
Author Tsumuki, Hisaaki| Kanehisa, Katsuo| Shiraga, Takashi| Kawada, Kazuo|
Published Date 1987-03
Publication Title 農学研究
Volume volume61
Issue issue3
Content Type Departmental Bulletin Paper