result 318 件
Author | Miyasou, Hideaki| Iwakawa, Kazuhide| Inagaki, Masaru| Kimura, Yuuji| Nishie, Manabu| Hamano, Ryousuke| Tokunaga, Naoyuki| Tunemitsu, Yousuke| Otsuka, Shinya| Iwagaki, Hiromi| |
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Published Date | 2012-04-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue1 |
Content Type | Journal Article |
Author | Kawahara, Masaki| Masuda, Masaharu| |
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Published Date | 2012-02-01 |
Publication Title | 岡山大学農学部学術報告 |
Volume | volume101 |
Content Type | Departmental Bulletin Paper |
Author | Otsuka, Shinzo| |
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Published Date | 1927-07-31 |
Publication Title | 岡山医学会雑誌 |
Volume | volume39 |
Issue | issue7 |
Content Type | Journal Article |
JaLCDOI | 10.18926/bgeou/47111 |
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FullText URL | bgeou_147_135_144.pdf |
Author | Mimura, Yukari| Ogura, Toshio| Otsuka, Fumio| |
Abstract | Thyroid stimulating hormone receptor antibody (TRAb) plays an important role in Graves' disease (GD). A second-generation measurement system has been developed and we have gotten a benefit by the system clinically. In this study, we determined 4 kinds of TRAb in 42 GD patients using the current and second-generation measurement systems to investigate the differences between them. The secondgeneration measurement system exhibited higher positive rates and inhibition rates of thyroid stimulating hormone (TSH) binding than those of the current system. Furthermore, 42 patients with GD were classified into 4 groups by GD activity. The actual values of all TRAbs and positive rates exhibited a tendency to increase significantly with GD activity. Of significance, 2 TRAbs in the second-generation measurement system exhibited high positive rates. However, all actual values of patients did not necessarily agree with these tendencies. The values of TRAb-human detecting anti-human TSH receptors at an approximate cut-off value reflected GD activity more accurately than those of TRAb-CT detecting anti-porcine TSH receptor. This suggests the possibility of specific differences between TSH receptors and further studies are required to further examine these effects. |
Keywords | Graves' disease human-TRAb TSAb |
Publication Title | 岡山大学大学院教育学研究科研究集録 |
Published Date | 2011-06-25 |
Volume | volume147 |
Start Page | 135 |
End Page | 144 |
ISSN | 1883-2423 |
language | English |
File Version | publisher |
NAID | 120003551002 |
JaLCDOI | 10.18926/AMO/47015 |
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FullText URL | 65_5_329.pdf |
Author | Matsumoto, Yoshinori| Sada, Ken-ei| Takano, Mariko| Toyota, Noriko| Yamanaka, Ryutaro| Sugiyama, Koichi| Wakabayashi, Hiroshi| Kawabata, Tomoko| Otsuka, Fumio| Makino, Hirofumi| |
Abstract | It is well known that infection is one of the major causes of morbidity and mortality in rheumatic disease patients treated with high-dose glucocorticoids, especially in the early phase after achievement of disease remission. The aim of this study was to identify the risk factors for infection, with a focus on the dose of glucocorticoids administered, following the achievement of disease remission in rheumatic diseases patients. We retrospectively analyzed the medical records of rheumatic disease patients who had been treated with glucocorticoids. The primary endpoint was the incidence rate of infection during a period from 1 to 2 months after the commencement of treatment. From April 2006 to March 2010, 19 of 92 patients suffered from infection during the observation period. Age≧65 yrs, presence of interstitial pneumonia, diagnosis of systemic vasculitis and serum creatinine level≧2.0mg/dl were found to be univariate predictors for infection. However, only the presence of interstitial pneumonia was an independent risk factor for infection (HR=4.50, 95%CI=1.65 to 14.44) by the Cox proportional hazard model. Even after achievement of clinical remission, careful observation is needed for patients with interstitial pneumonia, more so than for those receiving high-dose glucocorticoids. |
Keywords | infection rheumatic disease glucocorticoids interstitial pneumonia risk factors |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2011-10 |
Volume | volume65 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 329 |
End Page | 334 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 22037270 |
Web of Science KeyUT | 000296116400007 |
Author | Tsukamoto, Naoko| Otsuka, Fumio| Miyoshi, Tomoko| Inagaki, Kenichi| Nakamura, Eri| Suzuki, Jiro| Ogura, Toshio| Iwasaki, Yasumasa| Makino, Hirofumi| |
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Published Date | 2011-01-30 |
Publication Title | Molecular and Cellular Endocrinology |
Volume | volume332 |
Issue | issue1-2 |
Content Type | Journal Article |
Author | Momota, Ryusuke| Naito, Ichiro| Ninomiya, Yoshifumi| Ohtsuka, Aiji| |
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Published Date | 2011-05 |
Publication Title | Matrix Biology |
Volume | volume30 |
Issue | issue4 |
Content Type | Journal Article |
Author | Nishie, Manabu| Iwakawa, Kazuhide| Hamano, Ryousuke| Tokunaga, Naoyuki| Tunemitsu, Yousuke| Ootsuka, Shinya| Inagaki, Masaru| Iwagaki, Hiromi| Goubaru, Tomohiro| Fujita, Isao| Murakami, Takako| Tomoda, Jun| |
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Published Date | 2011-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume123 |
Issue | issue2 |
Content Type | Journal Article |
Author | Nishie, Manabu| Otsuka, Shinya| Tomoda, Jun| Fujiwara, Keishi| |
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Published Date | 2011-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume123 |
Issue | issue2 |
Content Type | Journal Article |
Author | Akiyama, Mari| Kobayashi, Katsuhiro| Yoshinaga, Harumi| Ohtsuka, Yoko| |
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Published Date | 2011-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume123 |
Issue | issue2 |
Content Type | Journal Article |
Author | Otsuka, Shinzo| |
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Published Date | 1928-04-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume40 |
Issue | issue4 |
Content Type | Journal Article |
Author | Otsuka, S.| |
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Published Date | 1929-05-31 |
Publication Title | 岡山医学会雑誌 |
Volume | volume41 |
Issue | issue5 |
Content Type | Journal Article |
Author | Ohtsuka, Shigeru| Terao, Hisafumi| Sugiu, Kizoh| |
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Published Date | 1932-09-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume44 |
Issue | issue9 |
Content Type | Journal Article |
Author | Otsuka, Nobuo| |
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Published Date | 1957-04-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume69 |
Issue | issue4 |
Content Type | Journal Article |
Author | Otsuka, Nobuo| |
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Published Date | 1957-04-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume69 |
Issue | issue4 |
Content Type | Journal Article |
Author | Otsuka, Nobuo| |
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Published Date | 1957-04-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume69 |
Issue | issue4 |
Content Type | Journal Article |
Author | Otsuka, Toshiaki| |
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Published Date | 2000-06-10 |
Publication Title | 岡山大学経済学会雑誌 |
Volume | volume32 |
Issue | issue1 |
Content Type | Article |
JaLCDOI | 10.18926/OER/40591 |
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Title Alternative | Dynamic Externalities of Industrial Agglomeration : A Survey |
FullText URL | oer_035_4_027_050.pdf |
Author | Otsuka, Akihiro| |
Abstract | This paper reviews existing literature on dynamic externalities which is the fountainhead of competitive advantages, and argues that rigorous theoretical and empirical analysis is needed to increase understanding of the role of technological spillovers in generating regional growth. Empirical analysis of knowledge spillovers is broadly performed in the field of industrial organization. Recently, a number of empirical analyses aiming at verifying technological spillovers accompanying R&D activity of companies have been conducted. In recent empirical literature on spatial agglomeration, many papers find evidence consistent with dynamic externalities. Especially, growing bodies of research have estimated the extent and type of dynamic externalities. Despite the different data sources used, methodologies are similar. As the survey of some methodologies has been carried out by McDonald (1997), this paper reviews the main empirical analyses of dynamic externalities as the complement−positioning. |
Publication Title | 岡山大学経済学会雑誌 |
Published Date | 2004-03-10 |
Volume | volume35 |
Issue | issue4 |
Start Page | 27 |
End Page | 50 |
ISSN | 0386-3069 |
language | Japanese |
File Version | publisher |
NAID | 120002647269 |
Author | Hamano, Ryosuke| Otsuka, Shinya| Kimura, Yuuji| Nishie, Manabu| Tokunaga, Naoyuki| Miyasou, Hideaki| Tsunemitu, Yousuke| Inagaki, Masaru| Iwakawa, Kazuhide| Iwagaki, Hiromi| |
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Published Date | 2010-12-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume122 |
Issue | issue3 |
Content Type | Journal Article |
Author | Yamashita, Toru| Kamiya, Tatsushi| Deguchi, Kentaro| Inaba, Toshiki| Zhang, Hanzhe| Shang, Jingwei| Miyazaki, Kazunori| Ohtsuka, Aiji| Katayama, Yasuo| Abe, Koji| |
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Published Date | 2010-12-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume122 |
Issue | issue3 |
Content Type | Journal Article |