このエントリーをはてなブックマークに追加


ID 32436
JaLCDOI
FullText URL
Author
Tanizaki, Yoshiro
Komagoe, Haruki
Sudo, Michiyasu
Ohtani, Jun
Kimura, Ikuro
Akagi, Katsumi
Townley, Robert G
Abstract

45Ca uptake and histamine release was examined in mast cells from rats sensitized with ovalbumin and Bordetella Bertussis as an adjuvant. The uptake of 45Ca by the mast cells was significantly increased by stimulation with ovalbumin as was the release of histamine from the mast cells. Nifedipine, a calcium antagonist, inhibited the increase in both 45Ca uptake and histamine release stimulated by ovalbumin, though the effect on 45Ca uptake was stronger than that on histamine release.

Keywords
mast cells
Ca2+ uptake
histamine release
Ca2+ antagonist
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1983-06
Volume
volume37
Issue
issue3
Publisher
Okayama University Medical School
Start Page
207
End Page
211
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT