| ID | 63907 |
| JaLCDOI | |
| FullText URL | |
| Author |
Tsuboi, Nobushige
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ishida, Joji
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Shimazu, Yosuke
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Edaki, Hisanori
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Uneda, Atsuhito
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Otani, Yoshihiro
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Fujii, Kentaro
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kurozumi, Kazuhiko
Department of Neurosurgery, Hamamatsu University School of Medicine
Ennishi, Daisuke
Center for Comprehensive Genomic Medicine, Okayama University Hospital
Yanai, Hiroyuki
Department of Pathology, Okayama University Hospital
Date, Isao
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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| Abstract | Glioneuronal tumor with neuropil-like islands (GNTNI) is a very rare subtype of glioneuronal tumor. We present a case of a 62-year-old man with GNTNI. Two adjacent lesions in the left parietal lobe were removed by left parietal craniotomy. The histological findings were glial cell proliferation and scattered rosettes consisting of synaptophysin-positive and NeuN-positive cells, leading to the diagnosis of GNTNI. Target sequencing revealed a genetic alteration similar to glioblastoma, IDH-wild type, which suggested adjuvant therapies. There are few previous reports on the treatment of this disease, and the patient should be followed carefully.
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| Keywords | glioneuronal tumor with neuropil-like islands
genomic profiling
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| Amo Type | Case Report
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2022-08
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| Volume | volume76
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| Issue | issue4
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| Publisher | Okayama University Medical School
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| Start Page | 473
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| End Page | 477
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID |
