| ID | 17113 |
| Eprint ID | 17113
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| FullText URL | |
| Title Alternative | The change of pulmonary surfactant during cardiopulmonary bypass
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| Author |
Yoshikawa, Naotaka
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| Abstract | It has been showed that the degeneration and disappearance of pulmonary surfactant is one of the causes of post-perfusion lung syndrome which occurs after cardiopulmonary bypass. An experimental study was undertaken to reveal the change of the osmiophilic body (a precursor of pulmonary surfactant) during cardiopulmonary bypass. Dogs were divided in 5 groups: I Control group II Group with whole blood III. Group with 20 % hemodilution IV. Group with no blood V Group with 20 % hemodilution and CDP-choline Results The following results were obtained: 1) Increase of osmiophilic bodies as ratio of the blood was increased in priming solution. 2) Increase of osmiophilic bodies in groups II, III and IV as cardiopulmonary bypass time was prolonged. 3) Osmiophilic bodies was markedly reduced by adding CDP-choline.
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| Published Date | 1977-04-30
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume89
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| Issue | issue3-4
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 469
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| End Page | 483
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/89/3-4/89_3-4_469/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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| language |
Japanese
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
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