| ID | 65155 |
| JaLCDOI | |
| FullText URL | |
| Author |
Obayashi, Atsuto
Department of Otorhinolaryngology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Aoki, Kazuma
Department of Otorhinolaryngology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Wada, Tadayoshi
Department of Otorhinolaryngology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Furuie, Hiromi
Department of Otorhinolaryngology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Kuraoka, Kazuya
Department of Diagnostic Pathology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Hamamoto, Takao
Department of Otorhinolaryngology, Head and Neck Surgery, Hiroshima University Hospital
Tatsukawa, Takaharu
Department of Otorhinolaryngology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center
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| Abstract | We describe the use of the tyrosine kinase inhibitor lenvatinib in a patient with brain tumor metastases from anaplastic thyroid carcinoma (ATC). A 52-year-old Japanese male presented with consciousness loss. Imaging revealed a thyroid tumor and multiple brain lesions. After the brain tumor’s resection, pathology results provided the diagnosis of ATC. Total thyroidectomy was performed, followed by whole-brain irradiation. Additional brain lesions later developed, and lenvatinib therapy was initiated with no remarkable complications. However, the treatment effects were limited, and the patient died 2 months after starting lenvatinib, 202 days after the initial brain surgery. Relevant literature is discussed.
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| Keywords | anaplastic thyroid carcinoma
brain metastasis
lenvatinib
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| Amo Type | Case Report
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2023-04
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| Volume | volume77
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| Issue | issue2
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| Publisher | Okayama University Medical School
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| Start Page | 227
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| End Page | 232
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID | |
| Web of Science KeyUT |
