| ID | 31261 |
| JaLCDOI | |
| FullText URL | |
| Author |
Obata, Takahiro
Watanabe, Akiharu
Hayashi, Shosaku
Takei, Nobuyuki
Sakata, Tatsuro
Shiota, Tetsuya
Higashi, Toshihiro
Itoshima, Tatsuya
Nagashima, Hideo
|
| Abstract | Cholestasis with hyperbilirubinemia was induced in female, but not male, Sprague-Dawley rats by daily treatment with phalloidin for 7 days. Increases in serum direct bilirubin level and alkaline phosphatase (Al-Pase) activity were observed concomitantly with diminished bile flow and a decreased output of bile acid and cholesterol. Light microscope findings of the liver revealed proliferated bile ductules and enhanced mitosis of hepatocytes. |
| Keywords | phalloidin
cholestasis
hyperbilirubinemia
mitosis
bile ductule.
|
| Amo Type | Article
|
| Publication Title |
Acta Medica Okayama
|
| Published Date | 1981-12
|
| Volume | volume35
|
| Issue | issue6
|
| Publisher | Okayama University Medical School
|
| Start Page | 411
|
| End Page | 415
|
| ISSN | 0386-300X
|
| NCID | AA00508441
|
| Content Type |
Journal Article
|
| language |
English
|
| File Version | publisher
|
| Refereed |
True
|
| PubMed ID | |
| Web of Science KeyUT |
