result 1721 件
| JaLCDOI | 10.18926/AMO/60797 |
|---|---|
| FullText URL | 74_5_381.pdf |
| Author | Yamamoto, Koichiro| Hanayama, Yoshihisa| Hasegawa, Kou| Tokumasu, Kazuki| Miyoshi, Tomoko| Hagiya, Hideharu| Ogawa, Hiroko| Obika, Mikako| Itoshima, Koichi| Otsuka, Fumio| |
| Abstract | To clarify the relevance of prolactin (PRL) to clinical parameters in patients who visited our general medicine department, medical records of 353 patients in whom serum PRL levels were measured during the period from 2016 to 2018 were retrospectively reviewed. Data for 140 patients (M/F: 42/98) were analyzed after excluding patients lacking detailed records and patients taking dopaminergic agents. Median serum PRL levels were significantly lower in males than females: 6.5 ng/ml (IQR: 4.2-10.3) versus 8.1 ng/ml (5.9-12.9), respectively. Pain and general fatigue were the major symptoms at the first visit, and past histories of hypertension and dyslipidemia were frequent. Male patients with relatively high PRL levels (≥ 10 ng/ml) had significantly lower levels of serum albumin and significantly higher levels of serum LDH than those with low PRL (< 10 ng/ml). There were significant correlations of male PRL level with the erythrocyte sedimentation rate (R=0.62), serum LDH level (R=0.39) and serum albumin level (R=−0.52), while the level of serum CRP (R=0.33) showed an insignificant but weak positive correlation with PRL level. Collectively, these results show that PRL levels had gender-specific relevance to various clinical factors, with PRL levels in males being significantly related to inflammatory status. |
| Keywords | hormones hyperprolactinemia inflammation pituitary prolactin |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 381 |
| End Page | 389 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106693 |
| Web of Science KeyUT | 000581970100002 |
| NAID | 120006892923 |
| JaLCDOI | 10.18926/AMO/60796 |
|---|---|
| FullText URL | 74_5_371.pdf |
| Author | Makimoto, Go| Ohashi, Kadoaki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Abstract | The prognosis of advanced non-small cell lung cancer (NSCLC) patients has improved in recent decades, especially for patients with an oncogenic driver mutation. Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are effective for patients with the echinoderm microtubule-associated protein-like 4-ALK fusion gene. Several ALK-TKIs have been established: the first-generation ALK-TKI, crizotinib; second-generation ALK-TKIs, alectinib and ceritinib; and third-generation ALK-TKI, lorlatinib. Some ALK-TKIs are effective for tumors that are resistant to other ALK-TKIs; however, as is known in epidermal growth factor receptormutant lung cancer, tumor resistance is inevitable. ALK-positive NSCLCs acquire resistance via various mechanisms, making it a heterogeneous disease. Therefore, it is necessary to develop next-generation treatment strategies, such as the use of next-generation ALK-TKIs for secondary mutations, or combination therapies with ALK-TKIs and other TKIs. In this review, we summarize the development and use of ALK-TKIs, prior pivotal clinical trials, and resistance mechanisms. |
| Keywords | lung cancer anaplastic lymphoma kinase tyrosine kinase inhibitors resistance mechanism |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 371 |
| End Page | 379 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106692 |
| Web of Science KeyUT | 000581970100001 |
| NAID | 120006892922 |
| FullText URL | oer_052_2_contents_eng.pdf |
|---|---|
| Publication Title | Okayama Economic Review |
| Published Date | 2020-11-06 |
| Volume | volume52 |
| Issue | issue2 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2020 岡山大学経済学会 |
| File Version | publisher |
| JaLCDOI | 10.18926/OER/60794 |
|---|---|
| Title Alternative | Recent Trends in Currency Investment |
| FullText URL | oer_052_2_025_032.pdf |
| Author | Sakemoto, Ryuta| |
| Abstract | This paper surveys the recent trends in currency investment. In particular, this paper focuses upon strategies which employ cross-sectional information across countries. First, I introduce a carry trade that is the most popular investment strategy. Next, I explain developments of momentum and value strategies. Then, the other strategies are classifi ed into two groups. The former group exploits macroeconomic information such external debts and output growth. The latter group employs information in fi nancial markets such as term spreads and cross-sectional spot exchange rate return correlations. Finally, I describe two future research directions. |
| Publication Title | Okayama Economic Review |
| Published Date | 2020-11-06 |
| Volume | volume52 |
| Issue | issue2 |
| Start Page | 25 |
| End Page | 32 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2020 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120006892921 |
| JaLCDOI | 10.18926/OER/60793 |
|---|---|
| FullText URL | oer_052_2_013_024.pdf |
| Author | 津守 貴之| |
| Publication Title | Okayama Economic Review |
| Published Date | 2020-11-06 |
| Volume | volume52 |
| Issue | issue2 |
| Start Page | 13 |
| End Page | 24 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2020 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120006892920 |
| JaLCDOI | 10.18926/OER/60792 |
|---|---|
| Title Alternative | Input pricing under strategic delegation: Application of Cournot-Ikema curve |
| FullText URL | oer_052_2_001_011.pdf |
| Author | 大越 裕史| |
| Abstract | Once a fi rm is vertically integrated, it is well-known that such a firm has an incentive to delegate quantity decision to its downstream affiliate to increase its total profits by manipulating its input price. This kind of analysis has been analytically done but this note applies Ikema's diagrammatic demonstration to the model with a vertically integrated fi rm to show how to derive the market equilibrium in "quantity-price" plane diagrammatically. First, we derive the locus that firms' optimal supplies at any price level, which is called "Cournot-Ikema curve" and derive the equilibrium point which is identifi ed with the intersection of a demand curve and the Cournot-Ikema curve. This paper fi nds that strategic delegation rotates the curve clockwise with a fixed point at a price level equal to marginal cost. Finally, our model is extended to the case that a multinational enterprise manipulates transfer price, and shows that such a tax motivated transfer price further rotates the curve. |
| Publication Title | Okayama Economic Review |
| Published Date | 2020-11-06 |
| Volume | volume52 |
| Issue | issue2 |
| Start Page | 1 |
| End Page | 11 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2020 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120006892919 |
| FullText URL | oer_052_2_contents.pdf |
|---|---|
| Publication Title | Okayama Economic Review |
| Published Date | 2020-11-06 |
| Volume | volume52 |
| Issue | issue2 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2020 岡山大学経済学会 |
| File Version | publisher |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Adachi, Yuji| Koga, Kenichiro| |
| Note | This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Yuji Adachi and Kenichiro Koga Structure and phase behavior of highdensity ice from molecular-dynamics simulations with the ReaxFF potential. J. Chem. Phys. 153, 114501 (2020) and may be found at https://doi.org/10.1063/5.0016565.| |
| Published Date | 2020-09-16 |
| Publication Title | Journal of Chemical Physics |
| Volume | volume153 |
| Issue | issue11 |
| Publisher | American Institute of Physics |
| Start Page | 114501 |
| ISSN | 0021-9606 |
| NCID | AA00694991 |
| Content Type | Journal Article |
| Copyright Holders | © 2020 Author(s) |
| File Version | publisher |
| PubMed ID | 32962394 |
| DOI | 10.1063/5.0016565 |
| Web of Science KeyUT | 000574657400001 |
| Related Url | isVersionOf https://doi.org/10.1063/5.0016565 |
| Author | Kodama, Hiroyuki| Okazaki, Shingo| Jiang, Yifan| Yoden, Hiroyuki| Ohashi, Kazuhito| |
|---|---|
| Keywords | Carbon fiber reinforced plastic (CFRP) Grinding Grinding heat Heat-affected layer Heat condition analysis |
| Published Date | 2020-09 |
| Publication Title | Precision Engineering |
| Volume | volume65 |
| Publisher | Elsevier |
| Start Page | 53 |
| End Page | 63 |
| ISSN | 0141-6359 |
| NCID | AA00363145 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1016/j.precisioneng.2020.04.005 |
| Web of Science KeyUT | 000573306600006 |
| Related Url | isVersionOf https://doi.org/10.1016/j.precisioneng.2020.04.005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Xu, Naijin| Lin, Wenfeng| Sun, Jingkai| Sadahira, Takuya| Xu, Abai| Watanabe, Masami| Guo, Kai| Araki, Motoo| Li, Gonghui| Liu, Chunxiao| Nasu, Yasutomo| Huang, Peng| |
| Keywords | Nitroxoline Bladder cancer EMT immunotherapy preclinical model |
| Published Date | 2020-09-23 |
| Publication Title | Journal of Cancer |
| Volume | volume11 |
| Issue | issue22 |
| Publisher | Ivyspring International Publisher |
| Start Page | 6633 |
| End Page | 6641 |
| ISSN | 1837-9664 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The author(s). |
| File Version | publisher |
| PubMed ID | 33046984 |
| DOI | 10.7150/jca.47025 |
| Web of Science KeyUT | 000575099000017 |
| Related Url | isVersionOf https://doi.org/10.7150/jca.47025 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishimura, Yoshito| Harada, Ko| Koyama, Toshihiro| Hagiya, Hideharu| Otsuka, Fumio| |
| Keywords | Epidemiology Health policy Neurological disorders |
| Published Date | 2020-09-23 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 15509 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 32968173 |
| DOI | 10.1038/s41598-020-72519-0 |
| Web of Science KeyUT | 000573849300037 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-72519-0 |
| FullText URL | APL_117_101103.pdf |
|---|---|
| Author | Iida, Takumi | Ishikawa, Atsushi| Tanaka, Takuo| Muranaka, Atsuya| Uchiyama, Masanobu| Hayashi, Yasuhiko| Tsuruta, Kenji| |
| Note | This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Takumi Iida et. al. Super-chiral vibrational spectroscopy with metasurfaces for high-sensitive identification of alanine enantiomers. Appl. Phys. Lett. 117, 101103 (2020) and may be found at https://doi.org/10.1063/5.0012331.| |
| Published Date | 2020-09-09 |
| Publication Title | Applied Physics Letters |
| Volume | volume117 |
| Issue | issue10 |
| Publisher | American Institute of Physics |
| Start Page | 101103 |
| ISSN | 0003-6951 |
| NCID | AA00543431 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1063/5.0012331 |
| Web of Science KeyUT | 000571581400002 |
| Related Url | isVersionOf https://doi.org/10.1063/5.0012331 |
| FullText URL | RSC_Adv_10.pdf |
|---|---|
| Author | Guo, Yuxin| Yoshioka, Kaito| Hamao, Shino| Kubozono, Yoshihiro| Tani, Fumito| Goto, Kenta| Okamoto, Hideki| |
| Published Date | 2020-08-26 |
| Publication Title | RSC Advances |
| Volume | volume10 |
| Issue | issue52 |
| Publisher | Royal Society of Chemistry |
| Start Page | 31547 |
| End Page | 31552 |
| ISSN | 2046-2069 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry |
| File Version | publisher |
| DOI | 10.1039/D0RA06629J |
| Web of Science KeyUT | 000566579400055 |
| Related Url | isVersionOf https://doi.org/10.1039/D0RA06629J |
| FullText URL | Synlett_fulltext.pdf |
|---|---|
| Author | Mitsudo, Koichi| Habara, Nanae| Kobashi, Yoshiak| Kurimoto, Yuji| Mandai, Hiroki| Suga, Seiji| |
| Keywords | thienyl thioethers thioetherification one-pot synthesis metal-free halide-free thienoacenes |
| Note | This is an Accepted Manuscript of an article published by Thieme Gruppe.| |
| Published Date | 2020-09-21 |
| Publication Title | Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry |
| Volume | volume31 |
| Issue | issue19 |
| Publisher | Thieme Gruppe |
| Start Page | 1947 |
| End Page | 1952 |
| ISSN | 0936-5214 |
| NCID | AA10731110 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1055/s-0040-1707280 |
| Web of Science KeyUT | 000571827200001 |
| Related Url | isVersionOf https://www.doi.org/10.1055/s-0040-1707280 |
| FullText URL | AC_Int_ed_59_20.pdf |
|---|---|
| Author | Mitsudo, Koichi| Matsuo, Ren| Yonezawa, Toki| Inoue, Haruka| Mandai, Hiroki| Suga, Seiji| |
| Keywords | cross-coupling cyclization electrochemistry heterocycles synthetic methods |
| Note | This is the peer reviewed version of the following article: Mitsudo Koichi et. al. Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator. Angewandte Chemie International Edition 59(20) 7803-7807(2020), which has been published in final form at https://doi.org/10.1002/anie.202001149. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions This fulltext is available in Feb. 2021.| |
| Published Date | 2020-02-20 |
| Publication Title | Angewandte Chemie International Edition |
| Volume | volume59 |
| Issue | issue20 |
| Publisher | Wiley |
| Start Page | 7803 |
| End Page | 7807 |
| ISSN | 1433-7851 |
| NCID | AA11614189 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32077555 |
| DOI | 10.1002/anie.202001149 |
| Web of Science KeyUT | 000520531700001 |
| Related Url | isVersionOf https://doi.org/10.1002/anie.202001149 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nojima, Ichiro| Eikawa, Shingo| Tomonobu, Nahoko| Hada, Yoshiko| Kajitani, Nobuo| Teshigawara, Sanae| Miyamoto, Satoshi| Tone, Atsuhito| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Shikata, Kenichi| Udono, Heiichiro| Wada, Jun| |
| Keywords | Cytokines Diabetes Endocrine system and metabolic diseases Immunology Tumour immunology |
| Published Date | 2020-09-10 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 14928 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 32913271 |
| DOI | 10.1038/s41598-020-71946-3 |
| Web of Science KeyUT | 000571915100049 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-71946-3 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kojima, Toru| Umeda, Yuzo| Fuji, Tomokazu| Niguma, Takefumi| Satoh, Daisuke| Endo, Yoshikatsu| Sui, Kenta| Inagaki, Masaru| Oishi, Masahiro| Ota, Tetsuya| Hioki, Katsuyoshi| Matsuda, Tadakazu| Aoki, Hideki| Hirai, Ryuji| Kimura, Masashi| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Published Date | 2020-09-03 |
| Publication Title | PLOS ONE |
| Volume | volume15 |
| Issue | issue9 |
| Publisher | PUBLIC LIBRARY SCIENCE |
| Start Page | e0238392 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 Kojima et al. |
| File Version | publisher |
| PubMed ID | 32881910 |
| DOI | 10.1371/journal.pone.0238392 |
| Web of Science KeyUT | 000571063300054 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0238392 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sato, Yukiyo| Shamsi, Wajeeha| Jamal, Atif| Bhatti, Muhammad Faraz| Kondo, Hideki| Suzuki, Nobuhiro| |
| Keywords | fungal virus polymycovirus Fusarium oxysporum multisegmented RNA virus capsidless neo-virus lifestyle |
| Published Date | 2020-05-26 |
| Publication Title | mBio |
| Volume | volume11 |
| Issue | issue3 |
| Publisher | American Society for Microbiology |
| Start Page | e00450-20 |
| ISSN | 2150-7511 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 Sato et al. |
| File Version | publisher |
| PubMed ID | 32457242 |
| DOI | 10.1128/mBio.00450-20 |
| Web of Science KeyUT | 000572051800015 |
| Related Url | isVersionOf https://doi.org/10.1128/mBio.00450-20 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Abdelsalam, Sobhy S. H.| Kouzai, Yusuke| Watanabe, Megumi| Inoue, Komaki| Matsui, Hidenori| Yamamoto, Mikihiro| Ichinose, Yuki| Toyoda, Kazuhiro| Tsuge, Seiji| Mochida, Keiichi| Noutoshi, Yoshiteru| |
| Keywords | Fungi Microbiology Pathogens Plant immunity Plant sciences Transcription |
| Published Date | 2020-09-10 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 14889 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 32913311 |
| DOI | 10.1038/s41598-020-71968-x |
| Web of Science KeyUT | 000571915100010 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-71968-x |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitalo, Oscar W.| Otsuki, Takumi| Okada, Rui| Obitsu, Saeka| Masuda, Kanae| Hojo, Yuko| Matsuura, Takakazu| Mori, Izumi C.| Abe, Daigo| Asiche, William O.| Akagi, Takashi| Kubo, Yasutaka| Ushijima, Koichiro| |
| Keywords | 1-methylcyclopropene carotenoids chlorophyll Citrus limon ethylene low temperature peel degreening phytohormones transcriptome |
| Published Date | 2020-05-06 |
| Publication Title | Journal of Experimental Botany |
| Volume | volume71 |
| Issue | issue16 |
| Publisher | Oxford University Press |
| Start Page | 4778 |
| End Page | 4796 |
| ISSN | 0022-0957 |
| NCID | AA00697526 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020. |
| File Version | publisher |
| PubMed ID | 32374848 |
| DOI | 10.1093/jxb/eraa206 |
| Web of Science KeyUT | 000573250000015 |
| Related Url | isVersionOf https://doi.org/10.1093/jxb/eraa206 |
