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Author Izawa, Yositame|
Published Date 1923-03-31
Publication Title 岡山医学会雑誌
Volume volume35
Issue issue398
Content Type Journal Article
Author Izawa, Y.|
Published Date 1923-03-31
Publication Title 岡山医学会雑誌
Volume volume35
Issue issue398
Content Type Journal Article
Author Oïnuma, Sôroku|
Published Date 1924-12-31
Publication Title 岡山医学会雑誌
Volume volume36
Issue issue419
Content Type Journal Article
Author Ito, Koken|
Published Date 1924-08-31
Publication Title 岡山医学会雑誌
Volume volume36
Issue issue415
Content Type Journal Article
Author Ito, Koken|
Published Date 1924-05-31
Publication Title 岡山医学会雑誌
Volume volume36
Issue issue412
Content Type Journal Article
Author Matsumi, Junya| Morimatsu, Hiroshi| Matsusaki, Takashi| Kaku, Ryuji| Shimizu, Hiroko| Takahashi, Toru| Yagi, Takahito| Matsumi, Masaki| Morita, Kiyoshi|
Published Date 2012-02
Publication Title International Journal of Molecular Medicine
Volume volume29
Issue issue2
Content Type Journal Article
Author Hamazaki, Yukio|
Published Date 1925-11-30
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue430
Content Type Journal Article
Author Fujihara, Masao|
Published Date 1925-11-30
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue430
Content Type Journal Article
Author Hamazaki, Yukio|
Published Date 1925-10-31
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue429
Content Type Journal Article
Author Fujihara, Masao| Ito, Koken|
Published Date 1925-06-30
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue425
Content Type Journal Article
Author Ito, Koken| Fujihara, Masao|
Published Date 1925-04-30
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue423
Content Type Journal Article
FullText URL 37_411.pdf
Author Fujihara, Masao|
Note 原著|
Published Date 1925-04-30
Publication Title 岡山医学会雑誌
Volume volume37
Issue issue423
Publisher 岡山医学会
Start Page 411
End Page 422
ISSN 0030-1558
NCID AN00032489
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright© 岡山医学会
File Version publisher
DOI 10.4044/joma1889.37.423_411
Official Url https://www.jstage.jst.go.jp/article/joma1889/37/423/37_423_411/_article/-char/ja/|
Related Url http://www.okayama-u.ac.jp/user/oma/
Author Umena, Yasufumi| Kawakami, Keisuke| Shen, Jian-Ren| Kamiya, Nobuo|
Published Date 2011-05-05
Publication Title Nature
Volume volume473
Issue issue7345
Content Type Journal Article
Author 岡山大学法学会|
Published Date 2011-12-27
Publication Title 岡山大學法學會雜誌
Volume volume61
Issue issue2
Content Type Others
JaLCDOI 10.18926/AMO/47267
FullText URL 65_6_407.pdf
Author Shiota, Yutaro| Imai, Shigeo| Sasaki, Naomi| Tahara, Koo| Noma, Bunjiro| Horita, Naokatsu| Taniguchi, Akihiko| Ono, Tetsuya|
Abstract Mediastinal lymph node carcinoma of unknown primary site is rare and may have a better prognosis if extensive treatment is performed. Case, A 69-year-old-male presented with a persistent cough. Chest computed tomography (CT) demonstrated a large tumor 9.5×8.2cm, in the mediastinum, compressing the right main bronchus, the right pulmonary artery, and the superior vena cava. Because fiberoptic bronchoscopy was insufficient for diagnosis, mediastinoscopic tumor biopsy under general anesthesia was undertaken. Histological examination revealed adenocarcinoma. Extensive examinations revealed no other neoplastic lesion except in the mediastinum. Mediastinal lymph node carcinoma of unknown primary site was diagnosed. The patient was treated with docetaxel and cisplatin with concurrent thoracic radiation therapy. A month after the start of chemoradiotherapy, the mediastinal tumor regressed markedly. The patient remained free of symptoms without regrowth of the primary site. Exploration of the body showed no further abnormalities 20 months after disease onset.
Keywords mediastinal lymph node unknown primary site chemoradiation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 407
End Page 411
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189482
Web of Science KeyUT 000298516900008
JaLCDOI 10.18926/AMO/47266
FullText URL 65_6_403.pdf
Author Waseda, Koichi| Tanimoto, Yasushi| Ichiba, Shingo| Miyahara, Nobuaki| Murakami, Toshi| Ochi, Nobuaki| Terado, Michihisa| Nagano, Osamu| Maeda, Yoshinobu| Kanehiro, Arihiko| Ujike, Yoshihito| Tanimoto, Mitsune|
Abstract Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT). We here report a case of a 31-year woman with acute lymphatic leukemia, which was treated by chemotherapy and HSCT, and consequently developed BO 2 years after HSCT. A non-tuberculous mycobacterial infection occurred and showed gradual exacerbation. She started taking anti-mycobacterial drugs, but lost appetite, felt tired and finally lost consciousness one month after beginning medication. Arterial blood gas revealed marked hypercapnia. Using extracorporeal life support (ECLS), the carbon dioxide concentration was reduced and her consciousness recovered. To our knowledge, this is the first case in which ECLS was successfully used for hypercapnia in a patient with BO.
Keywords extracorporeal life support hypercapnia bronchiolitis obliterans noninvasive positive pressure ventilation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 403
End Page 406
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189481
Web of Science KeyUT 000298516900007
JaLCDOI 10.18926/AMO/47265
FullText URL 65_6_395.pdf
Author Harada, Sosuke| Sato, Shuhei| Suzuki, Etsuji| Okumura, Yoshihiro| Hiraki, Takao| Gobara, Hideo| Mimura, Hidefumi| Kanazawa, Susumu| Kaji, Mitsumasa| Fujiwara, Toshiyoshi|
Abstract The aim of the present study was to assess the diagnostic usefulness of Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in the prediction of local recurrence of malignant lung tumors by analyzing the pre-radiofrequency ablation (RFA) maximal standardized uptake value (SUVmax). We performed a historical cohort study of consecutive malignant lung tumors treated by RFA from January 2007 to May 2008 at Okayama University Hospital. We selected only lung tumors examined by PET/CT within 90 days before RFA and divided them (10 primary and 29 metastatic) into 3 groups according to their tertiles of SUVmax. We calculated recurrence odds ratios in the medium group and the high group compared to the low group using multivariate logistic analysis. After we examined the relationship between SUVmax and recurrence in a crude model, we adjusted for some factors. Tumors with higher SUVmax showed higher recurrence odds ratios (medium group;1.84, high group;4.14, respectively). The tumor size also increased the recurrence odds ratio (2.67);we thought this was mainly due to selection bias because we excluded tumors less than 10mm in diameter. This study demonstrated the pre-RFA SUVmax in PET/CT may be a prognostic factor for local recurrence of malignant lung tumors.
Keywords fluorodeoxyglucose (FDG) positron emission tomography (PET) standardized uptake value (SUV) radiofrequency ablation (RFA) lung
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 395
End Page 402
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189480
Web of Science KeyUT 000298516900006
JaLCDOI 10.18926/AMO/47264
FullText URL 65_6_387.pdf
Author Ohtsu, Tadahiro| Toda, Ryouhei| Shiraishi, Tomonobu| Toyoda, Hirokuni| Toyozawa, Hideyasu| Kamioka, Yasuaki| Ochiai, Hirotaka| Shimada, Naoki| Shirasawa, Takako| Hoshino, Hiromi| Kokaze, Akatsuki|
Abstract Empirical data indicative of the health conditions and medical needs of homeless persons are scarce in Japan. In this study, with the aim of contributing to the formulation of future healthcare strategies for the homeless, we conducted a self-administered questionnaire survey and interviews at a park in Shinjuku Ward, Tokyo, to clarify the living conditions of homeless persons and their health conditions and awareness about the availability of medical treatment. Responses from 55 homeless men were recorded (response rate:36.7%). With the exception of one person, none of them possessed a health insurance certificate. Half of the respondents reported having a current income source, although their modal monthly income was 30,000 yen($1 was approximately 90 yen). The number of individuals who responded "yes" to the questions regarding "Consulting a doctor on the basis of someone's recommendation" and "Being aware of the location of the nearest hospital or clinic" was significantly higher among those who had someone to consult when they were ill than among those who did not (the odds ratios [95% confidence intervals] were 15.00 [3.05-93.57] and 11.45 [1.42-510.68], respectively). This showed that whether or not a homeless person had a person to consult might influence his healthcare-seeking behavior. When queried about the entity they consulted (multiple responses acceptable), respondents mentioned "life support organizations" (61.1%) and "public offices" (33.3%). Overall, 94.5% of the respondents were aware of swine flu (novel influenza A (H1N1)). Their main sources of information were newspapers and magazines. On the basis of these findings, with regard to the aim of formulating healthcare strategies for homeless persons, while life support organizations and public offices play significant roles as conduits to medical institutions, print media should be considered useful for communicating messages to homeless persons.
Keywords homeless persons person to consult seeking medical treatment healthcare swine flu
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 387
End Page 393
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189479
Web of Science KeyUT 000298516900005
JaLCDOI 10.18926/AMO/47263
FullText URL 65_6_379.pdf
Author Shiraki, Teruo| Saito, Daiji|
Abstract The aim of this study was to clarify the prevalence of coronary risk factors in order to characterize the prognostic factors in elderly patients and to also identify any factors beneficial for the prevention of further cardiac events and death. We studied 888 patients with ST-elevation acute myocardial infarction who were admitted within 48h of symptom onset. The patients were divided into 3 groups according to age for comparison of variables:a younger group (n=99) aged<50, a middle-aged group (n=435)>51 years but<70 years and an elderly group (n=354) aged>71 years. The elderly group had higher rates of female gender, pulmonary congestion, in-hospital mortality, and atrial fibrillation and a higher plasma concentration of high-sensitivity CRP (hs-CRP) (p<0.05). Hypertension, diabetes mellitus, and dyslipidemia were more common in the middle-aged group (p<0.05). The prevalence of smokers and the plasma level of total cholesterol, LDL-cholesterol and triglycerides were lower in the elderly group (p<0.05). The grade of collateral circulation was highest in the elderly group, but the success rate of reperfusion therapy was lowest. Multiple regression analysis showed that age, pulmonary congestion, CKD and hs-CRP were predictors of in-hospital mortality.This investigation indicated that elderly patients with acute myocardial infarction have different clinical characteristics than younger patients. A specific algorithm might be needed in elderly patients, and could use hs-CRP, eGFR and atrial fibrillation as factors.
Keywords acute myocardial infarction coronary risk factor elderly
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 379
End Page 385
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189478
Web of Science KeyUT 000298516900004
JaLCDOI 10.18926/AMO/47262
FullText URL 65_6_369.pdf
Author Terada, Chuji| Yoshida, Aki| Nasu, Yoshihisa| Mori, Shuji| Tomono, Yasuko| Tanaka, Masato| Takahashi, Hideo K.| Nishibori, Masahiro| Ozaki, Toshifumi| Nishida, Keiichiro|
Abstract We investigated the expression and localization of high-mobility group box chromosomal protein-1 (HMGB-1) in human osteoarthritic (OA) cartilage in relation to the histopathological grade of cartilage destruction, and examined the role of HMGB-1 in the regulation of proinflammatory cytokine expression in chondrocytes. An immunohistochemical study demonstrated that total HMGB-1-positive cell ratios increase as the Osteoarthritis Research Society International (OARSI) histological grade increased. The population of cytoplasmic HMGB-1-positive chondrocytes was especially increased in the deep layers of higher-grade cartilage. The ratios and localization of receptors for advanced glycation end products (RAGE) expression by chondrocytes in Grade 2, 3, and 4 were significantly higher than those in Grade 1. In vitro stimulation with IL-1β, but not TNFα, significantly upregulated the expression of HMGB-1 mRNA by human OA chondrocytes. Both IL-1β and TNFα promoted the translocation of HMGB-1 from nuclei to cytoplasm. IL-1β and TNFα secretions were stimulated at higher levels of HMGB-1. The results of our study suggest the involvement of HMGB-1 in the pathogenesis of cartilage destruction in OA.
Keywords HMGB-1 RAGE chondrocyte osteoarthritis cartilage
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-12
Volume volume65
Issue issue6
Publisher Okayama University Medical School
Start Page 369
End Page 377
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22189477
Web of Science KeyUT 000298516900003