| ID | 13717 |
| Eprint ID | 13717
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| FullText URL | |
| Title Alternative | Immobilization stress affected free radicals, superoxide dismutase activity and thiobarbituric acid reactive substances in the rat brain
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| Author |
Okamura, Youko
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| Abstract | Immobilization stress for 6 hours induced hemorrhagic erosion in the rat stomach. Hydroxyl radicals singnificantly increased in the pons-medulla oblongata in stressed rats. Mitochondrial superoxide dismutase (SOD) activity was enhanced in the midbrain but was lowered in the cortex, hippocampus and cerebellum in stressed rats. Thiobarbituric acid reactive substances increased by stress in the cortex and midbrain. These finding suggested that immobilization stress generated hydroxyl radicals and accelerated lipid peroxidation, and affected mitocho-drial SOD activity which may lead to neuronal damage in stressed rats.
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| Keywords | 拘束ストレス
ヒドロキシルラジカル
スーパーオキシドジスムターゼ活性
チオバルビツール酸反応物質
脳
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| Note | 原著
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| Published Date | 1995-08-31
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume107
|
| Issue | issue7-8
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
|
| Start Page | 91
|
| End Page | 98
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/107/7-8/107_7-8_91/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
|
| language |
Japanese
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| Copyright Holders | 岡山医学会
|
| File Version | publisher
|
| Refereed |
True
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| Eprints Journal Name | joma
|
