result 19106 件
| FullText URL | K0005389_abstract_review.pdf K0005389_fulltext.pdf |
|---|---|
| Author | Izushi, Yasuhisa| |
| Published Date | 2016-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5389号 |
| Granted Date | 2016-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | CurrOpinStructBiol_39_46.pdf |
|---|---|
| Author | Suga, Michihiro| Qin, Xiaochun| Kuang, Tingyun| Shen, Jian-Ren| |
| Note | © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/| |
| Published Date | 2016-08 |
| Publication Title | Current Opinion in Structural Biology |
| Volume | volume39 |
| Publisher | CURRENT BIOLOGY LTD |
| Start Page | 46 |
| End Page | 53 |
| ISSN | 0959-440X |
| NCID | AA10836185 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| File Version | author |
| PubMed ID | 27131043 |
| DOI | 10.1016/j.sbi.2016.04.004 |
| Web of Science KeyUT | 000386411000008 |
| Related Url | https://doi.org/10.1016/j.sbi.2016.04.004 |
| Author | Ohtsuki, Takashi| Miki, Shunya| Kobayashi, Shouhei| Haraguchi, Tokuko| Nakata, Eiji| Hirakawa, Kazutaka| Sumita, Kensuke| Watanabe, Kazunori| Okazaki, Shigetoshi| |
|---|---|
| Published Date | 2015-12 |
| Publication Title | Scientific Reports |
| Volume | volume5 |
| Content Type | Journal Article |
| Author | Ohtsuki, Takashi| Kanzaki, Shigeto| Nishimura, Sae| Kunihiro, Yoshio| Sisido, Masahiko| Watanabe, Kazunori| |
|---|---|
| Published Date | 2016-08 |
| Publication Title | Nature Communications |
| Volume | volume7 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/54545 |
|---|---|
| Title Alternative | A Practical Study on the Services for New International Students |
| FullText URL | bhe_011_183_198.pdf |
| Author | Uzuka, Mariko| Oka, Masumi| |
| Abstract | 岡山大学において全学的な立場で新入留学生に対する受入支援を実施してきたのは、グローバル・パートナーズ（旧国際センター、留学生センター）の受入担当教員及び事務職員である。本稿では、主として、受入担当教員＝留学生相談指導担当教員がこれまでに実施してきた、新入留学生に対する来日後の受入支援の実態を明らかにした上で、2014 年度における新たな支援策の試みを検証し、それらの成果と課題について分析する。水野（2005）が指摘しているように、全ての留学生に対する「一次的援助サービス」及び一部の留学生に対する「二次的援助サービス」は、新入留学生が直面しがちな諸問題の発生を予防し、回避するのに有効である。本稿では、2014 年度に受入担当教員が交代したのを好機と捉え、「一次的援助サービス」の典型である「生活オリエンテーション」の実施方法改善の試みを検証し、「二次的援助サービス」の充実を目的として打ち出した新機軸と従来型の支援内容を整理分析し、新入留学生に対する支援のあり方を提言する。 |
| Publication Title | Bulletin of Higher Education Okayama University |
| Published Date | 2015-12-30 |
| Volume | volume11 |
| Start Page | 183 |
| End Page | 198 |
| ISSN | 1881-5952 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005838023 |
| JaLCDOI | 10.18926/54542 |
|---|---|
| Title Alternative | The Possibility of Japanese Language Teaching as a Support for International Students |
| FullText URL | bhe_011_139_150.pdf |
| Author | Moriya, Tomomi| |
| Abstract | 本稿では、近年、日本国内において受け入れが急増している留学生のための支援として、日本語教育にはどのようなことが期待され、どのような役割を果たすべきであるのか検討を行った。留学生の問題や支援に関わる先行研究の外観を通して、日本で学ぶ留学生が抱えやすい問題は多岐にわたっており、その支援のためのアプローチとして予防が重視されていることが示された。また、このような中で、日本語教育には留学生の対人接触の向上を支援することが求められるとともに、日本語教育に携わる者が異文化における留学生の心理に関する知識と理解をより一層深めていく必要性が確認された。 |
| Keywords | 留学生 問題 支援 日本語教育 予防的・教育的アプローチ |
| Publication Title | Bulletin of Higher Education Okayama University |
| Published Date | 2015-12-30 |
| Volume | volume11 |
| Start Page | 139 |
| End Page | 150 |
| ISSN | 1881-5952 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005838020 |
| JaLCDOI | 10.18926/54541 |
|---|---|
| FullText URL | bhe_011_127_138.pdf |
| Author | Prichard, Caleb| Fast, Thomas| |
| Abstract | Finnish education may be a model for Japanese universities as they look to promote active learning pedagogies. Based on observations and interviews with influential educators from several Finnish institutions, this article overviews key aspects of education in Finland, especially those related to deep learning. The role of faculty development, learning spaces, and co-teaching are also examined. Finally, a pilot course implemented at Okayama University in which the authors aimed to apply key ideas learned in Finland will be described. |
| Keywords | active learning deep learning Finnish education faculty development |
| Publication Title | Bulletin of Higher Education Okayama University |
| Published Date | 2015-12-30 |
| Volume | volume11 |
| Start Page | 127 |
| End Page | 138 |
| ISSN | 1881-5952 |
| language | English |
| File Version | publisher |
| NAID | 120005838019 |
| Author | Hanaya, Tadashi| Sato, Nobuaki| Yamamoto, Hiroshi| |
|---|---|
| Published Date | 2007-04 |
| Publication Title | Heterocycles |
| Volume | volume71 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54514 |
|---|---|
| FullText URL | 70_4_327.pdf |
| Author | Watanabe, Mototsugu| Yamamoto, Hiromasa| Eikawa, Shingo| Shien, Kazuhiko| Shien, Tadahiko| Soh, Junichi| Hotta, Katsuyuki| Wada, Jun| Hinotsu, Shiro| Fujiwara, Toshiyoshi| Kiura, Katsuyuki| Doihara, Hiroyoshi| Miyoshi, Shinichiro| Udono, Heiichiro| Toyooka, Shinichi| |
| Abstract | A study to evaluate the effect of metformin on the immune system was commenced in July 2014. Metformin is one of the most commonly prescribed drugs for type 2 diabetes, and previous studies have reported that metformin has an anti-tumor effect. The aim of this study is to evaluate the efficacy of metformin on the immune system in human cancer patients in vivo. The primary outcome parameter will be the rate change in the population of CD8＋ T cells, which produce multiple cytokines. |
| Keywords | metformin CD8＋ T cells cancer immunology |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 327 |
| End Page | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549683 |
| Web of Science KeyUT | 000384748600018 |
| JaLCDOI | 10.18926/AMO/54513 |
|---|---|
| FullText URL | 70_4_323.pdf |
| Author | Yamamoto, Naoki| Kato, Hironari| Mizukawa, Sho| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS. |
| Keywords | CH-EUS pancreatic tumor TIC |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 323 |
| End Page | 325 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549682 |
| Web of Science KeyUT | 000384748600017 |
| JaLCDOI | 10.18926/AMO/54511 |
|---|---|
| FullText URL | 70_4_313.pdf |
| Author | Matsumoto, Kazuyuki| Kato, Hironari| Tsutsumi, Koichiro| Mizukawa, Sho| Yabe, Syuntaro| Seki, Hiroyuki| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Yamamoto, Naoki| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Abstract | Recently, endoscopic ultrasonography (EUS)-guided ethanol ablation for small pancreatic neuroendocrine tumors (p-NETs) has been reported. However, the efficacy and safety of the technique remain unclear. We have launched a prospective pilot study of EUS-guided ethanol ablation for p-NETs. The major eligibility criteria are the presence of a pathologically diagnosed grade (G) 1 or G2 p-NET, a tumor size of 2cm, and being a poor candidate for surgery. A total of 5 patients will be treated. The primary endpoint will be the complete ablation rate at 1 month after treatment. |
| Keywords | pancreatic neuroendocrine tumor ethanol ablation EUS-guided |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 313 |
| End Page | 316 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549680 |
| Web of Science KeyUT | 000384748600015 |
| JaLCDOI | 10.18926/AMO/54510 |
|---|---|
| FullText URL | 70_4_307.pdf |
| Author | Fujiwara, Masaki| Inagaki, Masatoshi| Higuchi, Yuji| Uchitomi, Yosuke| Terada, Seishi| Kodama, Masafumi| Kishi, Yoshiki| Yamada, Norihito| |
| Abstract | Repetitive transcranial magnetic stimulation (rTMS) has been reported to be a new treatment option for treatment-resistant depression. In Japan, there has been limited research into its feasibility, efficacy, and tolerability. We have launched a trial of rTMS for treating medication-resistant major depressive disorder and bipolar depression. We are investigating low-frequency rTMS to the right dorsolateral prefrontal cortex and traditional high-frequency rTMS to the left dorsolateral prefrontal cortex, in 20 patients. The primary outcome of the study is the treatment completion rate. This study will provide new data on the usefulness of rTMS for treatment-resistant depression in Japan. |
| Keywords | repetitive transcranial magnetic stimulation depression treatment resistance low frequency |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 311 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549679 |
| Web of Science KeyUT | 000384748600014 |
| JaLCDOI | 10.18926/AMO/54509 |
|---|---|
| FullText URL | 70_4_303.pdf |
| Author | Iguchi, Toshihiro| Sakurai, Jun| Hiraki, Takao| Gobara, Hideo| Fujiwara, Hiroyasu| Matsui, Yusuke| Masaoka, Yoshihisa| Kanazawa, Susumu| |
| Abstract | This single center prospective study is being conducted to evaluate the safety of the cryoablation for patients with pathologically diagnosed painful bone and soft tissue tumors. Enrollment of 10 patients is planned over the 3-year recruitment period. Patients have related local pain after receiving medications or external radiation therapies will be included in this study. Cryoablation will be percutaneously performed under imaging guidance, and a temperature sensor will be used during treatment as necessary. The primary endpoint is prevalence of severe adverse events within 4 weeks after therapy. The secondary endpoint is effectiveness 4 weeks after the procedure. |
| Keywords | cryoablation soft tissue and bone tumor pain safety |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 303 |
| End Page | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549678 |
| Web of Science KeyUT | 000384748600013 |
| JaLCDOI | 10.18926/AMO/54508 |
|---|---|
| FullText URL | 70_4_299.pdf |
| Author | Wada, Koichiro| Uehara, Shinya| Ishii, Ayano| Sadahira, Takuya| Yamamoto, Masumi| Mitsuhata, Ritsuko| Takamoto , Atsushi| Araki, Motoo| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| Abstract | Urinary tract infections (UTIs) are the most common bacterial infections in women, and many patients experience frequent recurrence. The aim of this report is to introduce an on-going prospective phase II clinical trial performed to evaluate the preventive effectiveness of Lactobacillus vaginal suppositories for prevention of recurrent cystitis. Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322 strain of Lactobacillus crispatus every 2 days or 3 times a week for one year. The primary endpoint is recurrence of cystitis and the secondary endpoints are adverse events. Recruitment began in December 2013 and target sample size is 20 participants. |
| Keywords | probiotics lactobacilli Lactobacillus crispatus urinary tract infection vaginal suppository |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 299 |
| End Page | 302 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549677 |
| Web of Science KeyUT | 000384748600012 |
| JaLCDOI | 10.18926/AMO/54507 |
|---|---|
| FullText URL | 70_4_295.pdf |
| Author | Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Kubota, Risa| Yoshioka, Takashi| Ariyoshi, Yuichi| Kobayashi, Yasuyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hiroshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| Abstract | Although graft survival following renal transplantation (RTx) has improved, outcomes following highrisk RTx are variable. Preexisting antibodies, including donor-specific antibodies (DSA), play an important role in graft dysfunction and survival. We have designed a study to investigate the safety and efficacy of anti-CD20 monoclonal antibodies (rituximab) in high-risk RTx recipients. Major eligibility criteria include: 1) major and minor ABO blood group mismatch, 2) positive DSA. Thirty-five patients will receive 200 mg/body of rituximab. The primary endpoint is the incidence of B cell depletion. This study will clarify whether rituximab is efficacious in improving graft survival in high-risk RTx recipients. |
| Keywords | end-stage renal disease immunosuppression kidney transplantation |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 295 |
| End Page | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549676 |
| Web of Science KeyUT | 000384748600011 |
| JaLCDOI | 10.18926/AMO/54506 |
|---|---|
| FullText URL | 70_4_291.pdf |
| Author | Yoshioka, Norie| Shimo, Tsuyoshi| Ibaragi, Soichiro| Sasaki, Akira| |
| Abstract | Temporomandibular joint (TMJ) dislocation can occur during daily activities and negatively affect a patientʼs quality of life. Although both nonsurgical and surgical techniques have been used to treat recurrent TMJ dislocation, the former is not always successful and the latter, although having a high success rate, is invasive and requires hospitalization. Recently, autologous blood injection has been used to treat recurrent TMJ dislocation. However, this technique is not yet widely used in clinical practice. We designed this study to obtain further information as to efficacy, safety and stability of autologous blood injection for recurrent TMJ dislocation. |
| Keywords | autologous blood injection recurrent temporomandibular joint dislocation |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 294 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549675 |
| Web of Science KeyUT | 000384748600010 |
| JaLCDOI | 10.18926/AMO/54505 |
|---|---|
| FullText URL | 70_4_285.pdf |
| Author | Tanaka, Takashi| Gobara, Hideo| Inai, Ryota| Iguchi, Toshihiro| Tada, Akihiro| Sato, Shuhei| Yanai, Hiroyuki| Kanazawa, Susumu| |
| Abstract | We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion. |
| Keywords | 111Indium chloride scintigraphy SPECT/CT bone marrow reconversion 18F-FDG PET/CT bone metastasis |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 285 |
| End Page | 289 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549674 |
| Web of Science KeyUT | 000384748600009 |
| JaLCDOI | 10.18926/AMO/54504 |
|---|---|
| FullText URL | 70_4_279.pdf |
| Author | Nishimura, Yoshito| Iwamuro, Masaya| Ocho, Kazuki| Hasegawa, Kou| Kimura, Kosuke| Hanayama, Yoshihisa| Kondo, Eisei| Tanaka, Takehiro| Otsuka, Fumio| |
| Abstract | A 61-year-old Japanese man with IgG4-related autoimmune pancreatitis was referred to our hospital because of perspiration during food intake. Abdominal computed tomography (CT) with contrast media revealed multiple mesenteric lymphadenopathies. An open surgical abdominal biopsy and subsequent histopathological analysis revealed abnormally large lymphoid cells that were negative for CD3, CD5, and c-myc and positive for CD20 and bcl-2, leading to a diagnosis of diffuse large B-cell lymphoma. Here, we discuss the risk of malignancies, particularly malignant lymphoma in patients with IgG4-related disease. The importance of pathological analysis to reach the appropriate diagnosis in such cases should be emphasized. |
| Keywords | IgG4-related disease autoimmune pancreatitis immunophenotyping diffuse large B-cell lymphoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 283 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549673 |
| Web of Science KeyUT | 000384748600008 |
| JaLCDOI | 10.18926/AMO/54503 |
|---|---|
| FullText URL | 70_4_273.pdf |
| Author | Makimoto, Go| Miyahara, Nobuaki| Yoshikawa, Mao| Taniguchi, Akihiko| Kanehiro, Arihiko| Tanimoto, Mitsune| Kiura, Katsuyuki| |
| Abstract | Heerfordtʼs syndrome is a rare manifestation of sarcoidosis and is defined as a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. We report a case of Heerfordtʼs syndrome presenting with a high fever and increased serum tumor necrosis factor alpha (TNF-α) levels. The patient had facial palsy, parotid swelling, uveitis, and swelling of the right supraclavicular and hilar lymph nodes. Corticosteroid therapy was initiated, and her symptoms soon resolved completely, in tandem with a decrease in TNF-α serum levels. |
| Keywords | Heerfordtʼs syndrome sarcoidosis TNF-α |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 273 |
| End Page | 277 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549672 |
| Web of Science KeyUT | 000384748600007 |
| JaLCDOI | 10.18926/AMO/54502 |
|---|---|
| FullText URL | 70_4_269.pdf |
| Author | Takeuchi, Miharu| Maruyama, Hidehiko| Oura, Naoko| Kanazawa, Akane| Nakata, Yusei| Minami, Susumu| Kikkawa, Kiyoshi| |
| Abstract | Twin anemia-polycythemia sequence (TAPS) is a group of disorders in monochorionic twins characterized by a large intertwin hemoglobin difference without amniotic fluid discordance. Reticulocyte count is used to diagnose this condition, but little is known about the role of erythroblasts, which are the prior stage of reticulocytes. In the present case of TAPS, the 25-yr-old Japanese mother showed no signs of oligohydramnios or polyhydramnios throughout gestation. The twins were born at 36 weeks and 6 days, weighing 2,648g and 1,994g. The intertwin hemoglobin difference in umbilical cord blood was (21.1－5.0＝) 16.1g/dL and the donor twin showed signs of chronic anemia, including myocardial hypertrophy and pericardial effusion. Erythroblastosis of the donor twin was prolonged (53,088.5, 42,114.8 and 44,217.9/μL on days 0, 1 and 2, respectively). Erythroblastosis, which indicates chronic anemia, is also a good diagnostic indicator of TAPS. |
| Keywords | anastomosis erythroblast monochorionic diamniotic twin reticulocyte twin anemia-polycythemia sequence |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 269 |
| End Page | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549671 |
| Web of Science KeyUT | 000384748600006 |
