Estimation of the frequency of the recessive gene of acatalasemia in Japan

The frequency of recessive gene, heterozygotes and homozygotes in Japanese acatalasemia were estimated as 0.0038, 7.5 X 10-3 and 3.0 X 10-5 by DAHLBERG'S formula, and estimated as 0.00087, 1.73 xl 0-3 and 4.23 X 10-6 by KIMURA'S formula. The frequency of recessive gene was calcu. lated from the frequency of hypocatalasemia obtained by the screening method as 0.00083, and it was almost identical with that calculated 1:'>y KIMURA'S formula. The number of acatalasemia was estimated as about 423 by KIMURA'S formula.