result 722 件
| JaLCDOI | 10.18926/AMO/67873 |
|---|---|
| FullText URL | 78_6_465.pdf |
| Author | Ocho, Kazuki| Hagiya, Hideharu| Ishikawa, Hisashi| Otsuka, Fumio| |
| Abstract | An 81-year-old Japanese man with a medical history of diabetes mellitus and hypertension was diagnosed with the novel coronavirus disease 2019 (COVID-19). The patient developed pain in the bilateral shoulders and hips 3 days after the disease onset and presented to our outpatient clinic after 1 month. Referring to diagnostic criteria, we diagnosed him with polymyalgia rheumatica (PMR). We initiated prednisolone at 15 mg per day and his symptoms improved immediately. The clinical course of the patient indicated that the SARS-CoV-2 infection triggered the onset of autoimmune disease, PMR in this case. |
| Keywords | COVID-19 SARS-CoV-2 polymyalgia rheumatica autoimmune diseases human leukocyte antigen |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-12 |
| Volume | volume78 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 465 |
| End Page | 468 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39719320 |
| Web of Science KeyUT | 001397269500002 |
| JaLCDOI | 10.18926/AMO/67872 |
|---|---|
| FullText URL | 78_6_459.pdf |
| Author | Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| Abstract | Traumatic neuroma is an abnormal proliferation of injured nerves resulting from trauma or surgery. We present a case of traumatic neuroma arising in the cystic duct after cholecystectomy. A 66-year-old man was referred to our department due to a biliary tumor. He had undergone cholecystectomy 20 years prior. Cholangioscopy showed an elevated lesion covered with smooth mucosa. Histological examination revealed normal bile duct mucosa. Although benign disease was suspected, the possibilities of malignant disease could not be excluded. Extrahepatic bile duct resection was planned to include intraoperative rapid-freezing of a biopsy specimen followed by histopathological examination. These intraoperative histology results showed proliferation of nerve and fibrous tissue only, resulting in the diagnosis of traumatic neuroma, so no lymph nodes were removed. To avoid excessive surgical intervention, histopathological examination of an intraoperative rapid-frozen biopsy specimen may be important for diagnosing traumatic neuroma. |
| Keywords | traumatic neuroma biliary stricture cholecystectomy cholangiography intraoperative rapid-frozen biopsy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-12 |
| Volume | volume78 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 459 |
| End Page | 464 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39719319 |
| Web of Science KeyUT | 001397269500001 |
| JaLCDOI | 10.18926/AMO/67871 |
|---|---|
| FullText URL | 78_6_453.pdf |
| Author | Kawata, Yujiro| Watanabe, Kenta| Tokiya, Ryoji| Matsuno, Takeshi| Tanaka, Ryo| Taira, Naruto| Katsui, Kuniaki| |
| Abstract | Radiation-induced angiosarcoma (RIAS) is a rare, late adverse event of radiotherapy comprising approximately half of all radiation-induced sarcomas. It has a relatively short latency period and generally unfavorable prognosis. This study presents a case of RIAS that developed 5 years and 11 months after the completion of hypofractionated radiotherapy (42.56 Gy/16 fractions) following partial mastectomy. The patient was diagnosed with RIAS 10 months after the onset of skin redness. She underwent skin tumor resection, followed by paclitaxel, then pazopanib administration, but no radiotherapy. At 6 years and 2 months after surgery, no RIAS recurrence has been detected. |
| Keywords | breast cancer hypofractionated radiotherapy radiation-induced angiosarcoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-12 |
| Volume | volume78 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 453 |
| End Page | 458 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39719318 |
| Web of Science KeyUT | 001397808000001 |
| JaLCDOI | 10.18926/AMO/67870 |
|---|---|
| FullText URL | 78_6_449.pdf |
| Author | Kato, Gentaro| Ogawa, Tatsuya| Hayashida, Tomohiro| Shimizu, Shuji| Yamamoto, Shu| Shichijo, Takeshi| |
| Abstract | A 73-year-old man who had undergone esophagectomy and retrosternal gastric tube reconstruction for esophageal cancer 8 years prior was transferred to our hospital for the treatment of an acute myocardial infarction. Emergent percutaneous coronary intervention for the left anterior descending artery (#7) was successfully performed. However, echocardiography revealed a ventricular septal rupture (25×27 mm). Seventeen days after admission, the rupture was successfully treated with a double-patch closure via a left anterolateral thoracotomy to avoid a surgical injury to his retrosternal gastric tube. Determining the best surgical approach to the heart is important for safe cardiac surgery in patients after esophageal reconstruction. |
| Keywords | acute myocardial infarction ventricular septal rupture retrosternal gastric tube reconstruction esophageal cancer left anterolateral thoracotomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-12 |
| Volume | volume78 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 449 |
| End Page | 452 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39719317 |
| Web of Science KeyUT | 001397799300003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Inukai-Motokura, Yumi| Ninomiya, Kiichiro| Baba, Takahiro| Omori, Hiroki| Takeguchi, Tetsuya| Uno, Mari| Ayada, Yoshiyuki| Tanaka, Takehiro| Maeda, Yoshinobu| Ohashi, Kadoaki| |
| Keywords | Pulmonary sclerosing pneumocytoma Ipilimumab Nivolumab Programmed cell death ligand 1 Case report |
| Published Date | 2024-11-29 |
| Publication Title | International Cancer Conference Journal |
| Volume | volume14 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 60 |
| End Page | 63 |
| ISSN | 2192-3183 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| DOI | 10.1007/s13691-024-00737-8 |
| Web of Science KeyUT | 001366705400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s13691-024-00737-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuo, Toshihiko| Iwamoto, Yoshitaka| Okamoto, Hironori| Iguchi, Daisuke| |
| Keywords | infective endocarditis maxillary sinusitis ocular proptosis orbital vascular malformation streptococcus anginosus |
| Published Date | 2024-11-30 |
| Publication Title | Cureus |
| Volume | volume16 |
| Issue | issue11 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | e74873 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Copyright 2024 Matsuo et al. |
| File Version | publisher |
| DOI | 10.7759/cureus.74873 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.74873 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kanemoto, Hideka| Obata, Kyoichi| Kadoya, Koichi| Ono, Kisho| Kawai, Hotaka| Kunisada, Yuki| Yao, Mayumi| Ibaragi, Soichiro| |
| Published Date | 2024-10-28 |
| Publication Title | Case Reports in Dentistry |
| Volume | volume2024 |
| Publisher | Wiley |
| Start Page | 8836103 |
| ISSN | 2090-6447 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Hideka Kanemoto et al. |
| File Version | publisher |
| PubMed ID | 39503010 |
| DOI | 10.1155/2024/8836103 |
| Web of Science KeyUT | 001352105100001 |
| Related Url | isVersionOf https://doi.org/10.1155/2024/8836103 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishimura, Seitaro| Noma, Kazuhiro| Kawasaki, Kento| Hashimoto, Masashi| Kato, Takuya| Maeda, Naoaki| Tanabe, Shunsuke| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi| |
| Keywords | Gastro-tracheal fistula Esophageal cancer Retrosternal route Esophageal surgery |
| Note | The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-02052-z| |
| Published Date | 2024-11-04 |
| Publication Title | Surgical Case Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 252 |
| ISSN | 2198-7793 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024. |
| File Version | publisher |
| PubMed ID | 39489816 |
| DOI | 10.1186/s40792-024-02052-z |
| Web of Science KeyUT | 001347685400001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40792-024-02052-z |
| JaLCDOI | 10.18926/AMO/67667 |
|---|---|
| FullText URL | 78_5_423.pdf |
| Author | Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Hishida, Ai| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| Abstract | Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital’s emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases. |
| Keywords | 111In-pentetreotide nesidioblastosis single-photon emission computed tomography hyperinsulinemic hypoglycemia |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 423 |
| End Page | 428 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467661 |
| Web of Science KeyUT | 001343346400009 |
| JaLCDOI | 10.18926/AMO/67666 |
|---|---|
| FullText URL | 78_5_413.pdf |
| Author | Kashihara, Kenichi| Irisawa, Minoru| Takao, Wataru| |
| Abstract | We investigated patients with migraine or migraine variants who exhibited focal cerebral hypoperfusion on arterial spin-labeled (ASL) magnetic resonance (MR) imaging along with neurological symptoms. Fourteen patients with migraine demonstrated focal cerebral hypoperfusion. Three other patients did not have a history of recurrent headaches but exhibited comparable cerebral hypoperfusion to migraine patients on ASL-MRI in addition to neurological symptoms. Patients with migraine may present with neurological symptoms associated with cortical spreading depression during, after, or even without a headache phase. Additionally, the isolated neurological symptoms may be caused by a pathophysiology identical to that of migraine but without presenting with recurrent headaches. |
| Keywords | arterial spin-labeled magnetic resonance imaging cortical spreading depression migraine complex migraine without headache vertigo |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 413 |
| End Page | 421 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467660 |
| JaLCDOI | 10.18926/AMO/67665 |
|---|---|
| FullText URL | 78_5_407.pdf |
| Author | Shimoyama, Kyoko| Nakajima, Atsushi| Minari, Yoshimitsu| |
| Abstract | Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but they have been known to cause immune-related adverse events (irAEs) by promoting T-cell activation. Neurological irAEs are rare (1%) but have a high fatality rate (11.5%). Here we report the first case of Bickerstaff brainstem encephalitis (BBE) induced by an ICI. A woman in her 60s with metastatic breast cancer was treated with atezolizumab plus nab-paclitaxel once intravenously. Eighteen days later, she lost consciousness with ophthalmoplegia and was diagnosed with a neurological irAE. She recovered consciousness immediately with the administration of intravenous immunoglobulin (IVIG) but suffered severe permanent peripheral neuropathy. Although it is just one case, this experience shows that BBE occurring as a neurological irAE of ICI cancer treatment may be associated with more severe outcomes than conventional BBE in metastatic cancer. Creating a system for multidisciplinary treatment is essential for ICI therapy. |
| Keywords | Bickerstaff brainstem encephalitis immune checkpoint inhibitor atezolizumab neurological immune-related adverse event breast cancer |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 407 |
| End Page | 412 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467659 |
| Web of Science KeyUT | 001343346400007 |
| JaLCDOI | 10.18926/AMO/67664 |
|---|---|
| FullText URL | 78_5_401.pdf |
| Author | Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi| |
| Abstract | Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas. |
| Keywords | child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 401 |
| End Page | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467658 |
| Author | Ninomiya, Kiichiro| Ennishi, Daisuke| Okamoto, Kunio| Ando, Midori| Nakamura, Satoko| Tomida, Shuta| Ayada, Yoshiyuki| Makimoto, Go| Ichihara, Eiki| Okita, Natsuko| Toyooka, Shinichi| Maeda, Yoshinobu| Tabata, Masahiro| |
|---|---|
| Note | This is an Accepted Manuscript of an article published by American Society of Clinical Oncology (ASCO).| This fulltext file will be available in Sep. 2025.| |
| Published Date | 2024-09-19 |
| Publication Title | JCO Precision Oncology |
| Volume | volume8 |
| Publisher | American Society of Clinical Oncology (ASCO) |
| Start Page | e2400228 |
| ISSN | 2473-4284 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by American Society of Clinical Oncology. |
| File Version | author |
| PubMed ID | 39298692 |
| DOI | 10.1200/po.24.00228 |
| Web of Science KeyUT | 001328214400001 |
| Related Url | isVersionOf https://doi.org/10.1200/po.24.00228 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Minagi, Hitoshi| Kanaya, Nobuhiko| Kondo, Yoshitaka| Kakiuchi, Yoshihiko| Kuroda, Shinji| Shoji, Ryohei| Kashima, Hajime| Matsumi, Yuki| Kikuchi, Satoru| Shigeyasu, Kunitoshi| Teraishi, Fuminori| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Keywords | Myeloid sarcoma Chloroma Granulocytic sarcoma Bowel obstruction Abdominal pain |
| Note | The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-02030-5| |
| Published Date | 2024-10-04 |
| Publication Title | Surgical Case Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 229 |
| ISSN | 2198-7793 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024. |
| File Version | publisher |
| PubMed ID | 39365540 |
| DOI | 10.1186/s40792-024-02030-5 |
| Web of Science KeyUT | 001326038200001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40792-024-02030-5 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuo, Toshihiko| Kobayashi, Yasuyuki| Nishimura, Shingo| Yoshioka, Naoko| Takahashi, Yasushi| Iguchi, Yasutaka| |
| Keywords | Fungal endophthalmitis Intravitreal injection Fluconazole Nephrostomy Urinary tract infection Ureterolithiasis |
| Published Date | 2024-11 |
| Publication Title | Journal of Medical Cases |
| Volume | volume15 |
| Issue | issue11 |
| Publisher | Elmer Press, Inc. |
| Start Page | 359 |
| End Page | 366 |
| ISSN | 1923-4155 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The authors |
| File Version | publisher |
| PubMed ID | 39421221 |
| DOI | 10.14740/jmc4302 |
| Web of Science KeyUT | 001408599800009 |
| Related Url | isVersionOf https://doi.org/10.14740/jmc4302 |
| Author | Shimizu, Aiko| Makihara, Seiichiro| Imoto, Ryoji| Hirashita, Koji| Ando, Mizuo| |
|---|---|
| Keywords | Cerebrospinal fluid leakage Meningocele Transpterygoid approach Ipsilateral nasoseptal flap Bath-plug technique |
| Note | © 2024 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Aug. 2025.| |
| Published Date | 2024-10 |
| Publication Title | Auris Nasus Larynx |
| Volume | volume51 |
| Issue | issue5 |
| Publisher | Elsevier BV |
| Start Page | 875 |
| End Page | 879 |
| ISSN | 0385-8146 |
| NCID | AA00061157 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. |
| File Version | author |
| PubMed ID | 39163824 |
| DOI | 10.1016/j.anl.2024.08.003 |
| Web of Science KeyUT | 001313505100001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.anl.2024.08.003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hirono, Kinji| Takagi, Kosei| Yamada, Motohiko| Kimura, Jiro| Fuji, Tomokazu| Yasui, Kazuya| Nishiyama, Takeyoshi| Nagai, Yasuo| Kanehira, Noriyuki| Fujiwara, Toshiyoshi| |
| Keywords | Central pancreatectomy Pancreatoduodenectomy No reconstruction Glucose tolerance |
| Note | The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-02018-1| |
| Published Date | 2024-09-11 |
| Publication Title | Surgical Case Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 214 |
| ISSN | 2198-7793 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024. |
| File Version | publisher |
| PubMed ID | 39256230 |
| DOI | 10.1186/s40792-024-02018-1 |
| Web of Science KeyUT | 001309390800002 |
| Related Url | isVersionOf https://doi.org/10.1186/s40792-024-02018-1 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamashita, Masahiro| Higo, Hisao| Fujii, Nobuharu| Matsumoto, Chiaki| Makimoto, Go| Ninomiya, Kiichiro| Fujii, Masanori| Rai, Kammei| Ichihara, Eiki| Ohashi, Kadoaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Miyahara, Nobuaki| |
| Keywords | Chimeric antigen receptor-T cell therapy Coronavirus disease 2019 Multidrug therapy Organizing pneumonia |
| Published Date | 2024 |
| Publication Title | Respiratory Medicine Case Reports |
| Volume | volume51 |
| Publisher | Elsevier |
| Start Page | 102104 |
| ISSN | 2213-0071 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Authors. |
| File Version | publisher |
| DOI | 10.1016/j.rmcr.2024.102104 |
| Web of Science KeyUT | 001307936800001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.rmcr.2024.102104 |
| Title Alternative | A case of immune checkpoint inhibitor-associated colitis treated with infliximab |
|---|---|
| Author | Iwamuro, Masaya| Hiraoka, Sakiko| Otsuka, Motoyuki| |
| Abstract | A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary. |
| Keywords | インフリキシマブ（infliximab） 免疫関連有害事象（immune-related adverse events） 大腸炎（colitis） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2024-08-01 |
| Volume | volume136 |
| Issue | issue2 |
| Start Page | 69 |
| End Page | 73 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.136.69 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2024 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.136.69 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu| |
| Keywords | anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia |
| Published Date | 2024-08-22 |
| Publication Title | Psychiatry and Clinical Neurosciences Reports |
| Volume | volume3 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | e70003 |
| ISSN | 2769-2558 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The authors. |
| File Version | publisher |
| PubMed ID | 39184058 |
| DOI | 10.1002/pcn5.70003 |
| Web of Science KeyUT | 001295703300001 |
| Related Url | isVersionOf https://doi.org/10.1002/pcn5.70003 |
